메뉴 건너뛰기




Volumn 56, Issue 1, 2005, Pages 61-68

Heat shock protein antibody titers are reduced by statin therapy in dyslipidemic subjects: A pilot study

Author keywords

[No Author keywords available]

Indexed keywords

ATORVASTATIN; C REACTIVE PROTEIN; HEAT SHOCK PROTEIN 60; HEAT SHOCK PROTEIN 65; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN ANTIBODY; LIPOPROTEIN; PROTEIN ANTIBODY; SIMVASTATIN; STATINE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 12944270424     PISSN: 00033197     EISSN: None     Source Type: Journal    
DOI: 10.1177/000331970505600108     Document Type: Article
Times cited : (23)

References (41)
  • 1
    • 0038124386 scopus 로고    scopus 로고
    • Molecular mimicry in atherosclerosis: A role for heat shock proteins in immunisation
    • Lamb DJ, El Sankary W, Ferns GAA: Molecular mimicry in atherosclerosis: A role for heat shock proteins in immunisation. Atherosclerosis 167:177-185, 2003.
    • (2003) Atherosclerosis , vol.167 , pp. 177-185
    • Lamb, D.J.1    El Sankary, W.2    Ferns, G.A.A.3
  • 2
    • 0033616886 scopus 로고    scopus 로고
    • Endothelial cytotoxicity mediated by serum antibodies to heat shock proteins of Escherichia coli and Chlamydia pneumoniae. Immune reactions to heat shock proteins as a possible link between infection and atherosclerosis
    • Mayr M, Metzler B, Kiechl S, et al: Endothelial cytotoxicity mediated by serum antibodies to heat shock proteins of Escherichia coli and Chlamydia pneumoniae. Immune reactions to heat shock proteins as a possible link between infection and atherosclerosis. Circulation 99:1560-1566, 1999.
    • (1999) Circulation , vol.99 , pp. 1560-1566
    • Mayr, M.1    Metzler, B.2    Kiechl, S.3
  • 3
    • 0034052160 scopus 로고    scopus 로고
    • Atherosclerosis - An autoimmune disease due to an immune reaction against heat-shock protein 60
    • Wick G: Atherosclerosis - an autoimmune disease due to an immune reaction against heat-shock protein 60. Herz 25:87-90, 2000.
    • (2000) Herz , vol.25 , pp. 87-90
    • Wick, G.1
  • 4
    • 0042334472 scopus 로고    scopus 로고
    • Serum heat shock protein 70 levels predict the development of atherosclerosis in subjects with established hypertension
    • Pockley AG, Georgiades A, Thulin T, et al: Serum heat shock protein 70 levels predict the development of atherosclerosis in subjects with established hypertension. Hypertension 42:235-238, 2003.
    • (2003) Hypertension , vol.42 , pp. 235-238
    • Pockley, A.G.1    Georgiades, A.2    Thulin, T.3
  • 5
    • 0030729601 scopus 로고    scopus 로고
    • Anti-heat shock protein (hsp)72 antibodies are present in patients with Graves' disease (GD) and in smoking control subjects
    • Prummel MF, VanPareren Y, Bakker O, et al: Anti-heat shock protein (hsp)72 antibodies are present in patients with Graves' disease (GD) and in smoking control subjects. Clin Exp Immunol 110:292-295, 1997.
    • (1997) Clin Exp Immunol , vol.110 , pp. 292-295
    • Prummel, M.F.1    VanPareren, Y.2    Bakker, O.3
  • 6
    • 0033554448 scopus 로고    scopus 로고
    • Association of serum antibodies to heat-shock protein 65 with carotid atherosclerosis. Clinical significance determined in a follow-up study
    • Xu QB, Kiechl S, Mayr M, et al: Association of serum antibodies to heat-shock protein 65 with carotid atherosclerosis. Clinical significance determined in a follow-up study. Circulation 100:1169-1174, 1999.
    • (1999) Circulation , vol.100 , pp. 1169-1174
    • Xu, Q.B.1    Kiechl, S.2    Mayr, M.3
  • 7
    • 0034447972 scopus 로고    scopus 로고
    • Prognostic value of antibody titre to heat-shock protein 65 on cardiovascular events
    • Hoppichler F, Koch T, Dzien A, et al: Prognostic value of antibody titre to heat-shock protein 65 on cardiovascular events. Cardiology 94:220-223, 2000.
    • (2000) Cardiology , vol.94 , pp. 220-223
    • Hoppichler, F.1    Koch, T.2    Dzien, A.3
  • 8
    • 0035957031 scopus 로고    scopus 로고
    • Antibodies to human heat-shock protein 60 are associated with the presence and severity of coronary artery disease. Evidence for an autoimmune component of atherogenesis
    • Zhu JH, Quyyumi AA, Rott D, et al: Antibodies to human heat-shock protein 60 are associated with the presence and severity of coronary artery disease. Evidence for an autoimmune component of atherogenesis. Circulation 103:1071-1075, 2001.
    • (2001) Circulation , vol.103 , pp. 1071-1075
    • Zhu, J.H.1    Quyyumi, A.A.2    Rott, D.3
  • 9
    • 0035570685 scopus 로고    scopus 로고
    • Temporal expression of heat shock proteins 60 and 70 at lesion-prone sites during atherogenesis in ApoE-deficient mice
    • Kanwar RK, Kanwar JR, Wang DM, et al: Temporal expression of heat shock proteins 60 and 70 at lesion-prone sites during atherogenesis in ApoE-deficient mice. Arterioscler Thromb Vasc Biol 21:1991-1997, 2001.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1991-1997
    • Kanwar, R.K.1    Kanwar, J.R.2    Wang, D.M.3
  • 10
    • 0032976306 scopus 로고    scopus 로고
    • Enhanced fatty streak formation in C57BL/6J mice by immunization with heat shock protein-65
    • George J, Shoenfeld Y, Afek A, et al: Enhanced fatty streak formation in C57BL/6J mice by immunization with heat shock protein-65. Arterioscler Thromb Vasc Biol 19:505-510, 1999.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 505-510
    • George, J.1    Shoenfeld, Y.2    Afek, A.3
  • 11
    • 0033848123 scopus 로고    scopus 로고
    • Immunization of low-density lipoprotein receptor-deficient (LDL-RD) mice with heat shock protein 65 (HSP-65) promotes early atherosclerosis
    • Afek A, George J, Gilburd B, et al: Immunization of low-density lipoprotein receptor-deficient (LDL-RD) mice with heat shock protein 65 (HSP-65) promotes early atherosclerosis. J Autoimmun 14:115-121, 2000.
    • (2000) J Autoimmun , vol.14 , pp. 115-121
    • Afek, A.1    George, J.2    Gilburd, B.3
  • 12
    • 0035499399 scopus 로고    scopus 로고
    • Accelerated intimal thickening in carotid arteries of balloon-injured rats after immunization against heat shock protein 70
    • George J, Greenberg S, Barshack I, et al: Accelerated intimal thickening in carotid arteries of balloon-injured rats after immunization against heat shock protein 70. J Am Coll Cardiol 38:1564-1569, 2001.
    • (2001) J Am Coll Cardiol , vol.38 , pp. 1564-1569
    • George, J.1    Greenberg, S.2    Barshack, I.3
  • 13
    • 0027987849 scopus 로고
    • Randomized trial of cholesterol-lowering in 4,444 patients with coronary-heart-disease - The Scandinavian Simvastatin Survival Study (4S)
    • Pedersen TR, Kjekshus J, Berg K, et al: Randomized trial of cholesterol-lowering in 4,444 patients with coronary-heart-disease - the Scandinavian Simvastatin Survival Study (4S). Lancet 344:1383-1389, 1994.
    • (1994) Lancet , vol.344 , pp. 1383-1389
    • Pedersen, T.R.1    Kjekshus, J.2    Berg, K.3
  • 14
    • 0028883828 scopus 로고
    • Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia
    • Shepherd J, Cobbe SM, Ford I, et al: Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. N Engl J Med 333:1301-1307, 1995.
    • (1995) N Engl J Med , vol.333 , pp. 1301-1307
    • Shepherd, J.1    Cobbe, S.M.2    Ford, I.3
  • 15
    • 0037840242 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5,963 people with diabetes: A randomised placebo-controlled trial
    • Collins R, Armitage J, Parish S, et al: MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5,963 people with diabetes: A randomised placebo-controlled trial. Lancet 361:2005-2016, 2003.
    • (2003) Lancet , vol.361 , pp. 2005-2016
    • Collins, R.1    Armitage, J.2    Parish, S.3
  • 16
    • 12944336041 scopus 로고    scopus 로고
    • Pleiotropic effects of statins may benefit cardiovascular system
    • [Anon]: Pleiotropic effects of statins may benefit cardiovascular system. Can J Cardiol 14:777, 1998.
    • (1998) Can J Cardiol , vol.14 , pp. 777
  • 17
    • 0033393022 scopus 로고    scopus 로고
    • Low-density lipoprotein-independent effects of statins
    • Davignon J, Laaksonen R: Low-density lipoprotein-independent effects of statins. Curr Opin Lipidol 10:543-559, 1999.
    • (1999) Curr Opin Lipidol , vol.10 , pp. 543-559
    • Davignon, J.1    Laaksonen, R.2
  • 18
    • 0036736742 scopus 로고    scopus 로고
    • Statins reduce inflammation in atheroma of nonhuman primates independent of effects on serum cholesterol
    • Sukhova GK, Williams JK, Libby P: Statins reduce inflammation in atheroma of nonhuman primates independent of effects on serum cholesterol. Arterioscler Thromb Vasc Biol 22:1452-1458, 2002.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1452-1458
    • Sukhova, G.K.1    Williams, J.K.2    Libby, P.3
  • 19
    • 0242349750 scopus 로고    scopus 로고
    • Direct anti-inflammatory mechanisms contribute to attenuation of experimental allograft arteriosclerosis by statins
    • Shimizu K, Aikawa M, Takayama K, et al: Direct anti-inflammatory mechanisms contribute to attenuation of experimental allograft arteriosclerosis by statins. Circulation 108:2113-2120, 2003.
    • (2003) Circulation , vol.108 , pp. 2113-2120
    • Shimizu, K.1    Aikawa, M.2    Takayama, K.3
  • 20
    • 0142124353 scopus 로고    scopus 로고
    • Differential effects of statins on serum CRP levels: Implications of recent clinical trials
    • Ferns GAA: Differential effects of statins on serum CRP levels: Implications of recent clinical trials. Atherosclerosis 169:349-351, 2003.
    • (2003) Atherosclerosis , vol.169 , pp. 349-351
    • Ferns, G.A.A.1
  • 21
    • 0035192759 scopus 로고    scopus 로고
    • Anti-oxidative properties of fluvastatin, an HMG-CoA reductase inhibitor, contribute to prevention of atherosclerosis in cholesterol-fed rabbits
    • Rikitake Y, Kawashima S, Takeshita S, et al: Anti-oxidative properties of fluvastatin, an HMG-CoA reductase inhibitor, contribute to prevention of atherosclerosis in cholesterol-fed rabbits. Atherosclerosis 154:87-96, 2001.
    • (2001) Atherosclerosis , vol.154 , pp. 87-96
    • Rikitake, Y.1    Kawashima, S.2    Takeshita, S.3
  • 22
    • 0036162113 scopus 로고    scopus 로고
    • Cellular antioxidant effects of atorvastatin in vitro and in vivo
    • Wassmann S, Laufs U, Muller K, et al: Cellular antioxidant effects of atorvastatin in vitro and in vivo. Arterioscler Thromb Vasc Biol 22:300-305, 2002.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 300-305
    • Wassmann, S.1    Laufs, U.2    Muller, K.3
  • 23
    • 0036034385 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors as immunomodulators. Potential use in transplant rejection
    • Raggatt LJ, Partridge NC: HMG-CoA reductase inhibitors as immunomodulators. Potential use in transplant rejection. Drugs 62:2185-2191, 2002.
    • (2002) Drugs , vol.62 , pp. 2185-2191
    • Raggatt, L.J.1    Partridge, N.C.2
  • 24
    • 0037230935 scopus 로고    scopus 로고
    • Lymphocyte function-associated antigen-1 blockade by statins: Molecular basis and biological relevance
    • Weitz-Schmidt G: Lymphocyte function-associated antigen-1 blockade by statins: Molecular basis and biological relevance. Endothelium 10:43-47, 2003.
    • (2003) Endothelium , vol.10 , pp. 43-47
    • Weitz-Schmidt, G.1
  • 25
    • 0015348189 scopus 로고
    • Estimation of low-density lipoprotein cholesterol in plasma without the use of preparative ultracentrifugation
    • Friedewald WT, Levy RJ, Fredrickson DS: Estimation of low-density lipoprotein cholesterol in plasma without the use of preparative ultracentrifugation. Clin Chim Acta 18:499-502, 1972.
    • (1972) Clin Chim Acta , vol.18 , pp. 499-502
    • Friedewald, W.T.1    Levy, R.J.2    Fredrickson, D.S.3
  • 26
    • 0027399854 scopus 로고
    • Association of serum antibodies to heat-shock protein 65 with carotid atherosclerosis
    • Xu Q, Willeit J, Marosi M, et al: Association of serum antibodies to heat-shock protein 65 with carotid atherosclerosis. Lancet 341:255-259, 1993.
    • (1993) Lancet , vol.341 , pp. 255-259
    • Xu, Q.1    Willeit, J.2    Marosi, M.3
  • 27
    • 12944313596 scopus 로고    scopus 로고
    • Antibody titres to heat shock protein 60, 65, and 70 are elevated in dyslipidaemic patients with established CHD
    • Ghayour-Mobarhan M, Lamb DJ, Ferns GAA, et al: Antibody titres to heat shock protein 60, 65, and 70 are elevated in dyslipidaemic patients with established CHD (abstract). Atherosclerosis 5:120, 2004.
    • (2004) Atherosclerosis , vol.5 , pp. 120
    • Ghayour-Mobarhan, M.1    Lamb, D.J.2    Ferns, G.A.A.3
  • 28
    • 0035901619 scopus 로고    scopus 로고
    • Effects of hydroxymethyl glutaryl coenzyme A reductase inhibitor therapy on high-sensitivity C-reactive protein levels
    • Jialal I, Stein D, Balis D, et al: Effects of hydroxymethyl glutaryl coenzyme A reductase inhibitor therapy on high-sensitivity C-reactive protein levels. Circulation 103:1933-1935, 2001.
    • (2001) Circulation , vol.103 , pp. 1933-1935
    • Jialal, I.1    Stein, D.2    Balis, D.3
  • 29
    • 1642405502 scopus 로고    scopus 로고
    • Statins (HMG-CoA reductase inhibitors) reduce CD40 expression in human vascular cells
    • Mulhaupt F, Matter CM, Kwak BR, et al: Statins (HMG-CoA reductase inhibitors) reduce CD40 expression in human vascular cells. Cardiovasc Res 59:755-766, 2003.
    • (2003) Cardiovasc Res , vol.59 , pp. 755-766
    • Mulhaupt, F.1    Matter, C.M.2    Kwak, B.R.3
  • 30
    • 0242661386 scopus 로고    scopus 로고
    • Efficacy of fenofibrate and simvastatin on endothelial function and inflammatory markers in patients with combined hyperlipidemia: Relations with baseline lipid profiles
    • Wang TD, Chen WJ, Lin JW, et al: Efficacy of fenofibrate and simvastatin on endothelial function and inflammatory markers in patients with combined hyperlipidemia: Relations with baseline lipid profiles. Atherosclerosis 170:315-323, 2003.
    • (2003) Atherosclerosis , vol.170 , pp. 315-323
    • Wang, T.D.1    Chen, W.J.2    Lin, J.W.3
  • 31
    • 1642405502 scopus 로고    scopus 로고
    • Statins (HMG-CoA reductase inhibitors) reduce CD40 expression in human vascular cells
    • Mulhaupt F, Matter CM, Kwak BR, et al: Statins (HMG-CoA reductase inhibitors) reduce CD40 expression in human vascular cells. Cardiovasc Res 59:755-766, 2003.
    • (2003) Cardiovasc Res , vol.59 , pp. 755-766
    • Mulhaupt, F.1    Matter, C.M.2    Kwak, B.R.3
  • 32
    • 0038509017 scopus 로고    scopus 로고
    • Effects of fluvastatin on plasma levels of low-density lipoprotein subfractions, oxidized low-density lipoprotein, and soluble adhesion molecules: A twenty-four-week, open-label, dose-increasing study
    • Homma Y, Homma K, Iizuka S, et al: Effects of fluvastatin on plasma levels of low-density lipoprotein subfractions, oxidized low-density lipoprotein, and soluble adhesion molecules: A twenty-four-week, open-label, dose-increasing study. Curr Ther Res Clin Exp 64:236-247, 2003.
    • (2003) Curr Ther Res Clin Exp , vol.64 , pp. 236-247
    • Homma, Y.1    Homma, K.2    Iizuka, S.3
  • 33
    • 0037497392 scopus 로고    scopus 로고
    • Mechanism of simvastatin on induction of heat shock protein in osteoblasts
    • Wang X, Tokuda H, Hatakeyama D, et al: Mechanism of simvastatin on induction of heat shock protein in osteoblasts. Arch Biochem Biophys 415:6-13, 2003.
    • (2003) Arch Biochem Biophys , vol.415 , pp. 6-13
    • Wang, X.1    Tokuda, H.2    Hatakeyama, D.3
  • 34
    • 0036597058 scopus 로고    scopus 로고
    • Serum IgG to heat shock proteins and Porphyromonas gingivalis antigens in diabetic patients with periodontitis
    • Sims TJ, Lernmark A, Mancl LA, et al: Serum IgG to heat shock proteins and Porphyromonas gingivalis antigens in diabetic patients with periodontitis. J Clin Periodontol 29:551-562, 2002.
    • (2002) J Clin Periodontol , vol.29 , pp. 551-562
    • Sims, T.J.1    Lernmark, A.2    Mancl, L.A.3
  • 35
    • 0035949749 scopus 로고    scopus 로고
    • Effect of atorvastatin on LDL oxidation and antioxidants in normocholesterolemic type 2 diabetic patients
    • Oranje WA, Sels JP, Rondas-Colbers GJ, et al: Effect of atorvastatin on LDL oxidation and antioxidants in normocholesterolemic type 2 diabetic patients. Clin Chim Acta 311:91-94, 2001.
    • (2001) Clin Chim Acta , vol.311 , pp. 91-94
    • Oranje, W.A.1    Sels, J.P.2    Rondas-Colbers, G.J.3
  • 36
    • 10744225301 scopus 로고    scopus 로고
    • Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: A randomized controlled trial
    • Nissen SE, Tuzcu EM, Schoenhagen P, et al: Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: A randomized controlled trial. JAMA 291:1071-1080, 2004.
    • (2004) JAMA , vol.291 , pp. 1071-1080
    • Nissen, S.E.1    Tuzcu, E.M.2    Schoenhagen, P.3
  • 37
    • 11144355354 scopus 로고    scopus 로고
    • Intensive versus moderate lipid lowering with statins after acute coronary syndromes
    • Cannon CP, Braunwald E, McCabe CH, et al: Intensive versus moderate lipid lowering with statins after acute coronary syndromes. N Engl J Med 350:1495-1504, 2004.
    • (2004) N Engl J Med , vol.350 , pp. 1495-1504
    • Cannon, C.P.1    Braunwald, E.2    McCabe, C.H.3
  • 38
    • 0037313037 scopus 로고    scopus 로고
    • Effect of atorvastatin and pravastatin on serum C-reactive protein
    • Kent SM, Flaherty PJ, Coyle LC, et al: Effect of atorvastatin and pravastatin on serum C-reactive protein. Am Heart J 145:e8, 2003.
    • (2003) Am Heart J , vol.145
    • Kent, S.M.1    Flaherty, P.J.2    Coyle, L.C.3
  • 39
    • 0035806626 scopus 로고    scopus 로고
    • Effect of statin therapy on C-reactive protein levels. The Pravastatin Inflammation/CRP Evaluation (PRINCE): A randomized trial and cohort study
    • Albert MA, Danielson E, Rifai N, et al: Effect of statin therapy on C-reactive protein levels. The Pravastatin Inflammation/CRP Evaluation (PRINCE): A randomized trial and cohort study. JAMA 286:64-70, 2001.
    • (2001) JAMA , vol.286 , pp. 64-70
    • Albert, M.A.1    Danielson, E.2    Rifai, N.3
  • 40
    • 0141888440 scopus 로고    scopus 로고
    • A statin-based inhibitor of lymphocyte function antigen-1 protects against ischemia/reperfusion-induced leukocyte adhesion in the colon
    • Wan MX, Schramm R, Klintman D, et al: A statin-based inhibitor of lymphocyte function antigen-1 protects against ischemia/reperfusion-induced leukocyte adhesion in the colon. Br J Pharmacol 140:395-401, 2003.
    • (2003) Br J Pharmacol , vol.140 , pp. 395-401
    • Wan, M.X.1    Schramm, R.2    Klintman, D.3
  • 41
    • 0028809489 scopus 로고
    • Autoantibodies against heat shock protein 60 mediate endothelial cytotoxicity
    • Schett G, Xu QB, Amberger A, et al: Autoantibodies against heat shock protein 60 mediate endothelial cytotoxicity. J Clin Invest 96:2569-2577, 1995.
    • (1995) J Clin Invest , vol.96 , pp. 2569-2577
    • Schett, G.1    Xu, Q.B.2    Amberger, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.