Vasodilatation in the rat dorsal hindpaw induced by activation of sensory neurons is reduced by paclitaxel

NeuroToxicology

Volumn 32, Issue 1, 2011, Pages 140-149

  Gracias, N G ^a   Cummins, T R ^a   Kelley, M R ^a   Basile, D P ^a   Iqbal, T ^a   Vasko, M R ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Calcitonin gene related peptide; Paclitaxel; Peripheral neuropathy; Sensory neurons; Vasodilatation

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CAPSAICIN; METHACHOLINE; PACLITAXEL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; ELECTROSTIMULATION; HINDLIMB; MALE; NERVE CELL PLASTICITY; NERVE CONDUCTION; NERVE FIBER C; NERVE POTENTIAL; NEUROTOXICITY; NEUROTRANSMITTER RELEASE; NONHUMAN; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SENSORY NERVE CELL; TOXICITY TESTING; VASODILATATION;

ANIMALS; CALCITONIN GENE-RELATED PEPTIDE; HINDLIMB; MALE; PACLITAXEL; RATS; RATS, SPRAGUE-DAWLEY; SENSORY RECEPTOR CELLS; VASODILATION;

ANIMALIA; RATTUS;

EID: 78951481493     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2010.09.006     Document Type: Article

References (53)

1. Andre N., Carre M., Brasseur G., Pourroy B., Kovacic H., Briand C., et al. Paclitaxel targets mitochondria upstream of caspase activation in intact human neuroblastoma cells. FEBS Lett 2002, 532:256-260.
2. Apfel S.C., Lipton R.B., Arezzo J.C., Kessler J.A. Nerve growth factor prevents toxic neuropathy in mice. Ann Neurol 1991, 29:87-90.
3. Augusto C., Pietro M., Cinzia M., Sergio C., Sara C., Luca G., et al. Peripheral neuropathy due to paclitaxel: study of the temporal relationships between the therapeutic schedule and the clinical quantitative score (QST) and comparison with neurophysiological findings. J Neurooncol 2008, 86:89-99.
4. Authier N., Gillet J.P., Fialip J., Eschalier A., Coudore F. Description of a short-term Taxol-induced nociceptive neuropathy in rats. Brain Res 2000, 887:239-249.
5. Brain S.D., Tippins J.R., Morris H.R., MacIntyre I., Williams T.J. Potent vasodilator activity of calcitonin gene-related peptide in human skin. J Invest Dermatol 1986, 87:533-536.
6. Brain S.D., Williams T.J., Tippins J.R., Morris H.R., MacIntyre I. Calcitonin gene-related peptide is a potent vasodilator. Nature 1985, 313:54-56.
7. Briasoulis E., Karavasilis V., Tzamakou E., Haidou C., Piperidou C., Pavlidis N. Pharmacodynamics of non-break weekly paclitaxel (Taxol) and pharmacokinetics of Cremophor-EL vehicle: results of a dose-escalation study. Anticancer Drugs 2002, 13:481-489.
8. Bulaj G., Zhang M.M., Green B.R., Fiedler B., Layer R.T., Wei S., et al. Synthetic muO-conotoxin MrVIB blocks TTX-resistant sodium channel NaV1.8 and has a long-lasting analgesic activity. Biochemistry 2006, 45:7404-7414.
9. Campana W.M., Eskeland N., Calcutt N.A., Misasi R., Myers R.R., O'Brien J.S. Prosaptide prevents paclitaxel neurotoxicity. Neurotoxicology 1998, 19:237-244.
10. Cata J.P., Weng H.R., Chen J.H., Dougherty P.M. Altered discharges of spinal wide dynamic range neurons and down-regulation of glutamate transporter expression in rats with paclitaxel-induced hyperalgesia. Neuroscience 2006, 138:329-338.
11. Cavaletti G., Cavalletti E., Montaguti P., Oggioni N., De Negri O., Tredici G. Effect on the peripheral nervous system of the short-term intravenous administration of paclitaxel in the rat. Neurotoxicology 1997, 18:137-145.
12. Cavaletti G., Cavalletti E., Oggioni N., Sottani C., Minoia C., D'Incalci M., et al. Distribution of paclitaxel within the nervous system of the rat after repeated intravenous administration. Neurotoxicolog 2000, 21:389-393.
13. Cavaletti G., Tredici G., Braga M., Tazzari S. Experimental peripheral neuropathy induced in adult rats by repeated intraperitoneal administration of taxol. Exp Neurol 1995, 133:64-72.
14. Chen J.J., Barber L.A., Dymshitz J., Vasko M.R. Peptidase inhibitors improve recovery of substance P and calcitonin gene-related peptide release from rat spinal cord slices. Peptides 1996, 17:31-37.
15. Chiba T., Yamaguchi A., Yamatani T., Nakamura A., Morishita T., Inui T., et al. Calcitonin gene-related peptide receptor antagonist human CGRP-(8-37). Am J Physiol 1989, 256:E331-E335.
16. Chin S.Y., Hall J.M., Brain S.D., Morton I.K. Vasodilator responses to calcitonin gene-related peptide (CGRP) and amylin in the rat isolated perfused kidney are mediated via CGRP1 receptors. J Pharmacol Exp Ther 1994, 269:989-992.
17. Chu D.Q., Legon S., Smith D.M., Costa S.K., Cuttitta F., Brain S.D. The calcitonin gene-related peptide (CGRP) antagonist CGRP(8-37) blocks vasodilatation in inflamed rat skin: involvement of adrenomedullin in addition to CGRP. Neurosci Lett 2001, 310:169-172.
18. Cliffer K.D., Siuciak J.A., Carson S.R., Radley H.E., Park J.S., Lewis D.R., et al. Physiological characterization of Taxol-induced large-fiber sensory neuropathy in the rat. Ann Neurol 1998, 43:46-55.
19. Dina O.A., Chen X., Reichling D., Levine J.D. Role of protein kinase Cepsilon and protein kinase A in a model of paclitaxel-induced painful peripheral neuropathy in the rat. Neuroscience 2001, 108:507-515.
20. Dougherty P.M., Cata J.P., Cordella J.V., Burton A., Weng H.R. Taxol-induced sensory disturbance is characterized by preferential impairment of myelinated fiber function in cancer patients. Pain 2004, 109:132-142.
21. Flatters S.J., Bennett G.J. Studies of peripheral sensory nerves in paclitaxel-induced painful peripheral neuropathy: evidence for mitochondrial dysfunction. Pain 2006, 122:245-257.
22. Forsyth P.A., Balmaceda C., Peterson K., Seidman A.D., Brasher P., DeAngelis L.M. Prospective study of paclitaxel-induced peripheral neuropathy with quantitative sensory testing. J Neurooncol 1997, 35:47-53.
23. Francis P., Rowinsky E., Schneider J., Hakes T., Hoskins W., Markman M. Phase I feasibility and pharmacologic study of weekly intraperitoneal paclitaxel: a Gynecologic Oncology Group pilot Study. J Clin Oncol 1995, 13:2961-2967.
24. Gracias N., Pu X., Klaunig J., Kelley M., Vasko M Paclitaxel treatment alters release of iCGRP and consequently contributes to decreased cutaneous blood flow 2008, Society for Neuroscience, Washington, DC, 668.14.
25. Howell S.L., Hii C.S., Shaikh S., Tyhurst M. Effects of taxol and nocodazole on insulin secretion from isolated rat islets of Langerhans. Biosci Rep 1982, 2:795-801.
26. Iniguez C., Larrode P., Mayordomo J.I., Gonzalez P., Adelantado S., Yubero A., et al. Reversible peripheral neuropathy induced by a single administration of high-dose paclitaxel. Neurology 1998, 51:868-870.
27. Jansen G., Lundeberg T., Kjartansson J., Samuelson U.E. Acupuncture and sensory neuropeptides increase cutaneous blood flow in rats. Neurosci Lett 1989, 97:305-309.
28. Kimura K., Low D.A., Keller D.M., Davis S.L., Crandall C.G. Cutaneous blood flow and sweat rate responses to exogenous administration of acetylcholine and methacholine. J Appl Physiol 2007, 102:1856-1861.
29. Koltzenburg M., Lewin G., McMahon S. Increase of blood flow in skin and spinal cord following activation of small diameter primary afferents. Brain Res 1990, 509:145-149.
30. Ligon L.A., Steward O. Role of microtubules and actin filaments in the movement of mitochondria in the axons and dendrites of cultured hippocampal neurons. J Comp Neurol 2000, 427:351-361.
31. Lipton R.B., Apfel S.C., Dutcher J.P., Rosenberg R., Kaplan J., Berger A., et al. Taxol produces a predominantly sensory neuropathy. Neurology 1989, 39:368-373.
32. Mielke S., Sparreboom A., Steinberg S.M., Gelderblom H., Unger C., Behringer D., et al. Association of Paclitaxel pharmacokinetics with the development of peripheral neuropathy in patients with advanced cancer. Clin Cancer Res 2005, 11:4843-4850.
33. Morris R.L., Hollenbeck P.J. Axonal transport of mitochondria along microtubules and F-actin in living vertebrate neurons. J Cell Biol 1995, 131:1315-1326.
34. Persohn E., Canta A., Schoepfer S., Traebert M., Mueller L., Gilardini A., et al. Morphological and morphometric analysis of paclitaxel and docetaxel-induced peripheral neuropathy in rats. Eur J Cancer 2005, 41:1460-1466.
35. Peters C.M., Jimenez-Andrade J.M., Jonas B.M., Sevcik M.A., Koewler N.J., Ghilardi J.R., et al. Intravenous paclitaxel administration in the rat induces a peripheral sensory neuropathy characterized by macrophage infiltration and injury to sensory neurons and their supporting cells. Exp Neurol 2007, 203:42-54.
36. Polomano R.C., Mannes A.J., Clark U.S., Bennett G.J. A painful peripheral neuropathy in the rat produced by the chemotherapeutic drug, paclitaxel. Pain 2001, 94:293-304.
37. Rendell M.S., Finnegan M.F., Healy J.C., Lind A., Milliken B.K., Finney D.E., et al. The relationship of laser-Doppler skin blood flow measurements to the cutaneous microvascular anatomy. Microvasc Res 1998, 55:3-13.
38. Richardson J.D., Vasko M.R. Cellular mechanisms of neurogenic inflammation. J Pharmacol Exp Ther 2002, 302:839-845.
39. Sahenk Z., Barohn R., New P., Mendell J.R. Taxol neuropathy. Electrodiagnostic and sural nerve biopsy findings. Arch Neurol 1994, 51:726-729.
40. Sarosy G., Kohn E., Stone D.A., Rothenberg M., Jacob J., Adamo D.O., et al. Phase I study of taxol and granulocyte colony-stimulating factor in patients with refractory ovarian cancer. J Clin Oncol 1992, 10:1165-1170.
41. Sato-Harada R., Okabe S., Umeyama T., Kanai Y., Hirokawa N. Microtubule-associated proteins regulate microtubule function as the track for intracellular membrane organelle transports. Cell Struct Funct 1996, 21:283-295.
42. Schiff P.B., Fant J., Horwitz S.B. Promotion of microtubule assembly in vitro by taxol. Nature 1979, 277:665-667.
43. Schiff P.B., Horwitz S.B. Taxol stabilizes microtubules in mouse fibroblast cells. Proc Natl Acad Sci USA 1980, 77:1561-1565.
44. Schmidt Y., Unger J.W., Bartke I., Reiter R. Effect of nerve growth factor on peptide neurons in dorsal root ganglia after taxol or cisplatin treatment and in diabetic (db/db) mice. Exp Neurol 1995, 132:16-23.
45. Shrestha S., Gracias N.G., Mujenda F., Khodorova A., Vasko M.R., Strichartz G.R. Local antinociception induced by endothelin-1 in the hairy skin of the rat's back. J Pain 2009, 10:702-714.
46. Siau C., Xiao W., Bennett G.J. Paclitaxel- and vincristine-evoked painful peripheral neuropathies: loss of epidermal innervation and activation of Langerhans cells. Exp Neurol 2006, 201:507-514.
47. Soma D., Kitayama J., Ishigami H., Kaisaki S., Nagawa H. Different tissue distribution of paclitaxel with intravenous and intraperitoneal administration. J Surg Res 2009, 155:142-146.
48. Steen K.H., Reeh P.W. Sustained graded pain and hyperalgesia from harmless experimental tissue acidosis in human skin. Neurosci Lett 1993, 154:113-116.
49. Steen K.H., Reeh P.W., Anton F., Handwerker H.O. Protons selectively induce lasting excitation and sensitization to mechanical stimulation of nociceptors in rat skin, in vitro. J Neurosci 1992, 12:86-95.
50. Thuret-Carnahan J., Bossu J.L., Feltz A., Langley K., Aunis D. Effect of taxol on secretory cells: functional, morphological, and electrophysiological correlates. J Cell Biol 1985, 100:1863-1874.
51. Tsui H.T., Lankford K.L., Ris H., Klein W.L. Novel organization of microtubules in cultured central nervous system neurons: formation of hairpin loops at ends of maturing neurites. J Neurosci 1984, 4:3002-3013.
52. Weng H.R., Aravindan N., Cata J.P., Chen J.H., Shaw A.D., Dougherty P.M. Spinal glial glutamate transporters downregulate in rats with taxol-induced hyperalgesia. Neurosci Lett 2005, 386:18-22.
53. Wiernik P.H., Schwartz E.L., Strauman J.J., Dutcher J.P., Lipton R.B., Paietta E., Phase I clinical and pharmacokinetic study of taxol. Cancer Res 1987, 47:2486-2493.