Antagonism of 5-HT 2A receptors inhibits the expression of pronociceptive mediator and enhances endogenous opioid mechanism in carrageenan-induced inflammation in rats

European Journal of Pharmacology

Volumn 654, Issue 1, 2011, Pages 33-41

  Huang, Jian ^a   Fan, Yanmei ^a   Jia, Yue ^a   Hong, Yanguo ^a  

^a FUJIAN NORMAL UNIVERSITY   (China)

Author keywords

5 HT 2A receptor; CGRP (Calcitonin gene related peptide); DRG (Dorsal root ganglia); Endogenous opioid mechanism; Inflammatory pain; Spinal dorsal horn

Indexed keywords

BETA ENDORPHIN; CALCITONIN GENE RELATED PEPTIDE; CARRAGEENAN; ENDORPHIN; KETANSERIN; MU OPIATE RECEPTOR; SEROTONIN 2A RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG TARGETING; IMMUNOCOMPETENT CELL; INFLAMMATION; LUMBAR SPINAL CORD; MALE; NOCICEPTION; NONHUMAN; PAIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL GANGLION;

ANIMALS; BETA-ENDORPHIN; CALCITONIN GENE-RELATED PEPTIDE; CARRAGEENAN; GANGLIA, SPINAL; INFLAMMATION; KETANSERIN; MALE; PAIN; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTORS, OPIOID, MU; SEROTONIN; SEROTONIN 5-HT2 RECEPTOR ANTAGONISTS; SPINAL CORD;

EID: 78951477699     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.12.007     Document Type: Article

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