Immunohistochemical localization of endomorphin-1 and endomorphin-2 in immune cells and spinal cord in a model of inflammatory pain

Journal of Neuroimmunology

Volumn 126, Issue 1-2, 2002, Pages 5-15

  Mousa, Shaaban A ^a   Machelska, Halina ^a   Schäfer, Michael ^a   Stein, Christoph ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Endomorphin; Immunohistochemistry; Inflammation; Opioid peptides; Opioid receptor

Indexed keywords

ENDOMORPHIN 1; ENDOMORPHIN 2; FREUND ADJUVANT; MU OPIATE RECEPTOR AGONIST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; LYMPH NODE; LYMPHADENITIS; LYMPHOCYTE; MACROPHAGE; MALE; MONOCYTE; MYELITIS; NONHUMAN; PAIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; RECEPTOR UPREGULATION; SPINAL CORD DORSAL HORN; SPINAL CORD NERVE CELL; SUBCUTANEOUS TISSUE;

ANIMALS; FREUND'S ADJUVANT; HINDLIMB; IMMUNOHISTOCHEMISTRY; LYMPH NODES; LYMPHOCYTES; MACROPHAGES; MALE; MONOCYTES; OLIGOPEPTIDES; PAIN; POSTERIOR HORN CELLS; RATS; RATS, WISTAR; SKIN;

EID: 0036094716     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(02)00049-8     Document Type: Article

References (24)

1. Immune cell-derived beta-endorphin
2. Methionine-enkephalin- and dynorphin A-release from immune cells and control of inflammatory pain
3. Increased content and transport of substance P and calcitonin gene-related peptide in sensory nerves innervating inflamed tissue: Evidence for a regulatory function of nerve growth factor in vivo
4. Reorganization of the spinal dorsal horn in models of chronic pain: Correlation with behaviour
5. Endomorphin-1 and endomorphin-2: Pharmacology of the selective endogenous mu-opioid receptor agonists
6. Novel opioid peptides endomorphin-1 and endomorphin-2 are present in mammalian immune tissues
7. Expression of μ-, δ-, and κ-opioid receptor-like immunoreactivities in rat dorsal root ganglia after carrageenan-induced inflammation
8. Pain control in inflammation governed by selectins
9. Expression of mu- and kappa-, but not delta-, opioid receptor mRNAs is enhanced in the spinal dorsal horn of the arthritic rats
10. Localization of endomorphin-2-like immunoreactivity in the rat medulla and spinal cord
11. Differential distribution of endomorphin 1- and endomorphin 2-like immunoreactivities in the CNS of the rodent
12. Beta-Endorphin-containing memory-cells and mu-opioid receptors undergo transport to peripheral inflamed tissue
13. Immunoreactivity for endomorphin-2 occurs in primary afferents in rats and monkey
14. Gene expression and localization of opioid peptides in immune cells of inflamed tissue: Functional role in antinociception
15. Opioid peptide-expressing leukocytes: Identification, recruitment, and simultaneously increasing inhibition of inflammatory pain
16. Immunofluorescent identification of endomorphin-2-containing nerve fibers and terminals in the rat brain and spinal cord
17. What do we know about the expression of proopiomelanocortin transcripts and related peptides in lymphoid tissue?
18. Opioid peptides and opioid receptors in cells of the immune system
19. Decreases in endomorphin-2-like immunoreactivity concomitant with chronic pain after nerve injury
20. The control of pain in peripheral tissue by opioids
21. Opioids from immunocytes interact with receptors on sensory nerves to inhibit nociception in inflammation
22. Peptide neuroanatomy of adjuvant-induced arthritic inflammation in rat
23. A potent and selective endogenous agonist for the mu-opiate receptor
24. Contribution of opioid receptors on primary afferent versus sympathetic neurons to peripheral opioid analgesia