Cell-permeable carboxyl-terminal p27Kip1 peptide exhibits anti-tumor activity by inhibiting Pim-1 kinase

Journal of Biological Chemistry

Volumn 286, Issue 4, 2011, Pages 2681-2688

  Morishita, Daisuke ^a,c   Takami, Miho ^a   Yoshikawa, Seiko ^b   Katayama, Ryohei ^a   Sato, Shigeo ^a   Kukimoto Niino, Mutsuko ^b   Umehara, Takashi ^b   Shirouzu, Mikako ^b   Sekimizu, Kazuhisa ^c   Yokoyama, Shigeyuki ^b,c   Fujita, Naoya ^a  

^a CANCER CHEMOTHERAPY CENTER   (Japan)

^b RIKEN   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-TUMOR ACTIVITIES; ANTICANCER DRUG; APOPTOSIS; CARBOXYL-TERMINAL; CELL-PERMEABLE; CHEMOTHERAPEUTIC AGENTS; CLINICAL USE; DEATH RATES; IN-CELL; IN-VITRO; IN-VIVO; LOW SENSITIVITY; PROSTATE CANCERS; TUMOR GROWTH; TUMORIGENESIS;

AMINO ACIDS; CELL DEATH; CHEMOTHERAPY; DISEASES; PHOSPHORYLATION; POPULATION STATISTICS; TUMORS;

PEPTIDES;

ARGININE; ASPARAGINE; CYCLIN DEPENDENT KINASE INHIBITOR 1B; PACLITAXEL; PROTEIN BAD; PROTEIN KINASE PIM 1; THREONINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL DEATH; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; ENZYME INHIBITION; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; WEIGHT REDUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-ASSOCIATED DEATH PROTEIN; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; G1 PHASE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM TRANSPLANTATION; PEPTIDES; PHOSPHORYLATION; PROSTATIC NEOPLASMS; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-PIM-1;

EID: 78951468972     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.092452     Document Type: Article

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