메뉴 건너뛰기




Volumn 41, Issue 2, 2011, Pages 537-548

Serum and organ-associated anti-hemoglobin humoral autoreactivity: Association with anti-Sm responses and inflammation

Author keywords

Anti hemoglobin autoantibodies; Autoimmunity; Systemic lupus erythematosus

Indexed keywords

AUTOANTIBODY; EPITOPE; HEMOGLOBIN; HEMOGLOBIN ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; METHEMOGLOBIN; MONOCLONAL ANTIBODY; PROTEIN SM; UNCLASSIFIED DRUG;

EID: 78851471285     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201040989     Document Type: Article
Times cited : (19)

References (48)
  • 1
    • 37649002483 scopus 로고    scopus 로고
    • Microvascular and microangiopathic antiphospholipid-associated syndromes ("MAPS"): semantic or antisemantic?
    • Asherson, R. A. and Cervera, R., Microvascular and microangiopathic antiphospholipid-associated syndromes ("MAPS"): semantic or antisemantic? Autoimmun. Rev. 2008. 7: 164-167.
    • (2008) Autoimmun. Rev. , vol.7 , pp. 164-167
    • Asherson, R.A.1    Cervera, R.2
  • 3
    • 0015056178 scopus 로고
    • Specificity and immunoglobulin characteristics of autoantibodies in acquired hemolytic anemia
    • Vos, G. H., Petz, L. D. and Fundenberg, H. H., Specificity and immunoglobulin characteristics of autoantibodies in acquired hemolytic anemia. J. Immunol. 1971. 106: 1172-1176.
    • (1971) J. Immunol. , vol.106 , pp. 1172-1176
    • Vos, G.H.1    Petz, L.D.2    Fundenberg, H.H.3
  • 4
    • 0027252129 scopus 로고
    • Erythrocyte membrane proteins reactive with human (warm-reacting) anti-red cell autoantibodies
    • Leddy, J. P., Falany, J. L., Kissel, G. E., Passador, S. T. and Rosenfeld, S. I., Erythrocyte membrane proteins reactive with human (warm-reacting) anti-red cell autoantibodies. J. Clin. Invest. 1993. 91: 1672-1680.
    • (1993) J. Clin. Invest. , vol.91 , pp. 1672-1680
    • Leddy, J.P.1    Falany, J.L.2    Kissel, G.E.3    Passador, S.T.4    Rosenfeld, S.I.5
  • 5
    • 0029134692 scopus 로고
    • Cytotoxic antibodies trigger inflammation through Fc receptors
    • Clynes, R. and Ravetch, J. V., Cytotoxic antibodies trigger inflammation through Fc receptors. Immunity 1995. 3: 21-26.
    • (1995) Immunity , vol.3 , pp. 21-26
    • Clynes, R.1    Ravetch, J.V.2
  • 6
    • 15944398355 scopus 로고    scopus 로고
    • The clinical sequelae of intravascular hemolysis and extravascular plasma hemoglobin: a novel mechanism of human disease
    • Rother, R. P., Bell, L., Hillmen, P. and Gladwin, M. T., The clinical sequelae of intravascular hemolysis and extravascular plasma hemoglobin: a novel mechanism of human disease. J. Am. Med. Ass. 2005. 293: 1653-1662.
    • (2005) J. Am. Med. Ass. , vol.293 , pp. 1653-1662
    • Rother, R.P.1    Bell, L.2    Hillmen, P.3    Gladwin, M.T.4
  • 7
    • 33846513576 scopus 로고    scopus 로고
    • Autoantibodies closely relate to the elevation level of in vivo hydrogen peroxide and tissue damage in systemic lupus erythematosus
    • Wang, Y., Qiao, B., Wang, Y., Han, X., Chu, Y. and Xiong, S., Autoantibodies closely relate to the elevation level of in vivo hydrogen peroxide and tissue damage in systemic lupus erythematosus. DNA Cell Biol. 2006. 25: 563-570.
    • (2006) DNA Cell Biol. , vol.25 , pp. 563-570
    • Wang, Y.1    Qiao, B.2    Wang, Y.3    Han, X.4    Chu, Y.5    Xiong, S.6
  • 8
    • 46049111412 scopus 로고    scopus 로고
    • Haptoglobin, inflammation and disease
    • Quaye, I. K., Haptoglobin, inflammation and disease. Trans. Royal Soc. Trop. Med. Hyg. 2008. 102: 735-742.
    • (2008) Trans. Royal Soc. Trop. Med. Hyg. , vol.102 , pp. 735-742
    • Quaye, I.K.1
  • 11
    • 0027298460 scopus 로고
    • Neurotoxicity of hemoglobin in cortical cell culture
    • Regan, R. F. and Panter, S. S., Neurotoxicity of hemoglobin in cortical cell culture. Neurosci. Lett. 1993. 153: 219-222.
    • (1993) Neurosci. Lett. , vol.153 , pp. 219-222
    • Regan, R.F.1    Panter, S.S.2
  • 12
    • 0030219945 scopus 로고    scopus 로고
    • Differences between normal and autoimmune T cell responses to autologous erythrocytes and haemoglobin: impairment of haptoglobin-mediated inhibition in NZB spleen cells
    • Calkins, C. E. and Esposito, M., Differences between normal and autoimmune T cell responses to autologous erythrocytes and haemoglobin: impairment of haptoglobin-mediated inhibition in NZB spleen cells. J. Autoimm. 1996. 9: 453-462.
    • (1996) J. Autoimm. , vol.9 , pp. 453-462
    • Calkins, C.E.1    Esposito, M.2
  • 13
    • 1842607674 scopus 로고    scopus 로고
    • Variable degree of alternative complement pathway-mediated hemolysis in Indian visceral leishmaniasis induced by differential expression of 9-O-acetylated sialoglycans
    • Chava, A. K., Chatterjee, M., Sharma, V., Sundar, S. and Mandal, C., Variable degree of alternative complement pathway-mediated hemolysis in Indian visceral leishmaniasis induced by differential expression of 9-O-acetylated sialoglycans. J. Infect. Dis. 2004. 189: 1257-1264.
    • (2004) J. Infect. Dis. , vol.189 , pp. 1257-1264
    • Chava, A.K.1    Chatterjee, M.2    Sharma, V.3    Sundar, S.4    Mandal, C.5
  • 14
    • 0041305806 scopus 로고    scopus 로고
    • A retrospective examination of anemia during infection of humans with Plasmodium vivax
    • Collins, W. E., Jeffery, G. M. and Roberts, J. M., A retrospective examination of anemia during infection of humans with Plasmodium vivax. Am. J. Trop. Med. Hyg. 2003. 68: 410-412.
    • (2003) Am. J. Trop. Med. Hyg. , vol.68 , pp. 410-412
    • Collins, W.E.1    Jeffery, G.M.2    Roberts, J.M.3
  • 15
    • 0024400358 scopus 로고
    • Autoantibody production by patients infected with Leishmania
    • Argov, S., Jaffe, C. L., Krupp, M., Slor, H. and Shoenfeld, Y., Autoantibody production by patients infected with Leishmania. Clin. Exp. Med. 1989. 76: 190-197.
    • (1989) Clin. Exp. Med. , vol.76 , pp. 190-197
    • Argov, S.1    Jaffe, C.L.2    Krupp, M.3    Slor, H.4    Shoenfeld, Y.5
  • 17
    • 0019956435 scopus 로고
    • Immunopathogenesis of systemic lupus erythematosus
    • Koffler, D., Biesecker, G. and Katz, S. M., Immunopathogenesis of systemic lupus erythematosus. Arthritis Rheum. 1982. 25: 858-861.
    • (1982) Arthritis Rheum. , vol.25 , pp. 858-861
    • Koffler, D.1    Biesecker, G.2    Katz, S.M.3
  • 18
    • 0020045904 scopus 로고
    • Neutrophil-mediated methemoglobin formation in the erythrocyte. The role of superoxide and hydrogen peroxide
    • Weiss, S. J., Neutrophil-mediated methemoglobin formation in the erythrocyte. The role of superoxide and hydrogen peroxide. J. Biol. Chem. 1982. 257: 2947-2953.
    • (1982) J. Biol. Chem. , vol.257 , pp. 2947-2953
    • Weiss, S.J.1
  • 19
    • 0014690279 scopus 로고
    • Circular dichroism of hemoglobin and its subunits in the Soret region
    • Nagai, M., Sugita, Y. and Yoneyama, Y., Circular dichroism of hemoglobin and its subunits in the Soret region. J. Biol. Chem. 1969. 244: 1651-1653.
    • (1969) J. Biol. Chem. , vol.244 , pp. 1651-1653
    • Nagai, M.1    Sugita, Y.2    Yoneyama, Y.3
  • 20
    • 63849094585 scopus 로고    scopus 로고
    • Haptoglobin preserves the CD163 hemoglobin scavenger pathway by shielding hemoglobin from peroxidative modification
    • Buehler, P. W., Abraham, B., Vallelian, F., Linnemayr, C., Pereira, C. P., Cipollo, J. F., Jia, Y. et al., Haptoglobin preserves the CD163 hemoglobin scavenger pathway by shielding hemoglobin from peroxidative modification. Blood 2009. 113: 2578-2586.
    • (2009) Blood , vol.113 , pp. 2578-2586
    • Buehler, P.W.1    Abraham, B.2    Vallelian, F.3    Linnemayr, C.4    Pereira, C.P.5    Cipollo, J.F.6    Jia, Y.7
  • 21
    • 59749086598 scopus 로고    scopus 로고
    • Endogenous humoral autoreactive immune responses to apoptotic cells: effects on phagocytic uptake, chemotactic migration and antigenic spread
    • Das, J., Arora, P., Gracias, D., Praveen, A., Raj, B. P., Martin, E. and Pal, R., Endogenous humoral autoreactive immune responses to apoptotic cells: effects on phagocytic uptake, chemotactic migration and antigenic spread. Eur. J. Immunol. 2008. 38: 3561-3574.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 3561-3574
    • Das, J.1    Arora, P.2    Gracias, D.3    Praveen, A.4    Raj, B.P.5    Martin, E.6    Pal, R.7
  • 22
    • 0017337322 scopus 로고
    • Avidity of anti-DNA antibodies in serum and IgG glomerular eluates from patients with systemic lupus erythematosus. Association of high avidity anti-native DNA antibody with glomerulonephritis
    • Winfield, J. B., Faiferman, I. and Koffler, D., Avidity of anti-DNA antibodies in serum and IgG glomerular eluates from patients with systemic lupus erythematosus. Association of high avidity anti-native DNA antibody with glomerulonephritis. J. Clin. Invest. 1977. 59: 90-96.
    • (1977) J. Clin. Invest. , vol.59 , pp. 90-96
    • Winfield, J.B.1    Faiferman, I.2    Koffler, D.3
  • 23
    • 0032490679 scopus 로고    scopus 로고
    • Immunization with a peptide surrogate for double-stranded DNA (dsDNA) induces autoantibody production and renal immunoglobulin deposition
    • Putterman, C. and Diamond, B., Immunization with a peptide surrogate for double-stranded DNA (dsDNA) induces autoantibody production and renal immunoglobulin deposition. J. Exp. Med. 1998. 188: 29-38.
    • (1998) J. Exp. Med. , vol.188 , pp. 29-38
    • Putterman, C.1    Diamond, B.2
  • 25
    • 33750322856 scopus 로고    scopus 로고
    • Specificity and effector mechanisms of autoantibodies in congenital heart block
    • Wahren-Herlenius, M. and Sonesson, S. E., Specificity and effector mechanisms of autoantibodies in congenital heart block. Curr. Opin. Immunol. 2006. 18: 690-696.
    • (2006) Curr. Opin. Immunol. , vol.18 , pp. 690-696
    • Wahren-Herlenius, M.1    Sonesson, S.E.2
  • 26
    • 67349140906 scopus 로고    scopus 로고
    • Oxidized haemoglobin as antigenic target of cell-mediated immune reactions in patients with carotid atherosclerosis
    • Profumo, E., Buttari, B. and Riganò, R., Oxidized haemoglobin as antigenic target of cell-mediated immune reactions in patients with carotid atherosclerosis. Autoimmun Rev. 2009. 8: 558-562.
    • (2009) Autoimmun Rev. , vol.8 , pp. 558-562
    • Profumo, E.1    Buttari, B.2    Riganò, R.3
  • 27
    • 0030999757 scopus 로고    scopus 로고
    • Hemoglobin-specific antibody in a multiply transfused patient with sickle cell disease
    • Noronha, P. A., Vida, L. N., Park, C. L. and Honig, G. R., Hemoglobin-specific antibody in a multiply transfused patient with sickle cell disease. Blood 1997. 89: 2155-2158.
    • (1997) Blood , vol.89 , pp. 2155-2158
    • Noronha, P.A.1    Vida, L.N.2    Park, C.L.3    Honig, G.R.4
  • 28
    • 33847343450 scopus 로고    scopus 로고
    • Newborn humans manifest autoantibodies to defined self molecules detected by antigen microarray informatics
    • Merbl, Y., Zucker-Toledano, M., Quintana, F. J. and Cohen, I. R., Newborn humans manifest autoantibodies to defined self molecules detected by antigen microarray informatics. J. Clin. Invest. 2007. 117: 712-718.
    • (2007) J. Clin. Invest. , vol.117 , pp. 712-718
    • Merbl, Y.1    Zucker-Toledano, M.2    Quintana, F.J.3    Cohen, I.R.4
  • 29
    • 0030444204 scopus 로고    scopus 로고
    • Genetic basis of systemic lupus erythematosus
    • Vyse, T. J. and Kotzin, B. L., Genetic basis of systemic lupus erythematosus. Curr. Opin. Immunol. 1996. 8: 843-851.
    • (1996) Curr. Opin. Immunol. , vol.8 , pp. 843-851
    • Vyse, T.J.1    Kotzin, B.L.2
  • 31
    • 0037087262 scopus 로고    scopus 로고
    • α-actinin is a cross-reactive renal target for pathogenic anti-DNA antibodies
    • Deocharan, B., Qing, X., Lichauco, J. and Putterman, C., α-actinin is a cross-reactive renal target for pathogenic anti-DNA antibodies. J. Immunol. 2002. 168: 3072-3078.
    • (2002) J. Immunol. , vol.168 , pp. 3072-3078
    • Deocharan, B.1    Qing, X.2    Lichauco, J.3    Putterman, C.4
  • 32
    • 0034536586 scopus 로고    scopus 로고
    • Hemoglobin binding sites on renal brush-border membranes
    • Gburek, J. and Osada, J., Hemoglobin binding sites on renal brush-border membranes. Biochimie 2000. 82: 1135-1142.
    • (2000) Biochimie , vol.82 , pp. 1135-1142
    • Gburek, J.1    Osada, J.2
  • 33
    • 0035525528 scopus 로고    scopus 로고
    • From T to B and back again: positive feedback in systemic autoimmune disease
    • Shlomchik, M. J., Craft, J. E. and Mamula, M. J., From T to B and back again: positive feedback in systemic autoimmune disease. Nat. Rev. Immunol. 2001. 1: 147-153.
    • (2001) Nat. Rev. Immunol. , vol.1 , pp. 147-153
    • Shlomchik, M.J.1    Craft, J.E.2    Mamula, M.J.3
  • 34
    • 17644404469 scopus 로고    scopus 로고
    • New therapies for systemic lupus erythematosus
    • Goldblatt, F. and Isenberg, D. A., New therapies for systemic lupus erythematosus. Clin. Exp. Immunol. 2005. 140: 205-212.
    • (2005) Clin. Exp. Immunol. , vol.140 , pp. 205-212
    • Goldblatt, F.1    Isenberg, D.A.2
  • 35
    • 34447099218 scopus 로고    scopus 로고
    • Systemic lupus erythematosus: Multiple immunological phenotypes in a complex genetic disease
    • Fairhurst, A.-M., Wandstrat, A. E. and Wakeland, E. K., Systemic lupus erythematosus: Multiple immunological phenotypes in a complex genetic disease. Adv. Immunol. 2006. 92: 1-69.
    • (2006) Adv. Immunol. , vol.92 , pp. 1-69
    • Fairhurst, A.-M.1    Wandstrat, A.E.2    Wakeland, E.K.3
  • 36
    • 0034094660 scopus 로고    scopus 로고
    • Monoclonal anti-double-stranded DNA autoantibody stimulates the expression and release of IL-1β, IL-6, IL-8, IL-10 and TNF-α from normal human mononuclear cells involving in the lupus pathogenesis
    • Sun, K.-H., Yu, C.-L., Tang, S.-J. and Sun, G.-H., Monoclonal anti-double-stranded DNA autoantibody stimulates the expression and release of IL-1β, IL-6, IL-8, IL-10 and TNF-α from normal human mononuclear cells involving in the lupus pathogenesis. Immunology 2000. 99: 352-360.
    • (2000) Immunology , vol.99 , pp. 352-360
    • Sun, K.-H.1    Yu, C.-L.2    Tang, S.-J.3    Sun, G.-H.4
  • 37
    • 85047693371 scopus 로고    scopus 로고
    • Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9
    • Means, T. K., Latz, E., Hayashi, F., Murali, M. R., Golenbock, D. T. and Luster, A. D., Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9. J. Clin. Invest. 2005. 115: 407-417.
    • (2005) J. Clin. Invest. , vol.115 , pp. 407-417
    • Means, T.K.1    Latz, E.2    Hayashi, F.3    Murali, M.R.4    Golenbock, D.T.5    Luster, A.D.6
  • 38
    • 28544449709 scopus 로고    scopus 로고
    • Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8
    • Vollmer, J., Tluk, S., Schmitz, C., Hamm, S., Jurk, M., Forsbach, A., Akira, S. et al., Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8. J. Exp. Med. 2005. 202: 1575-1585.
    • (2005) J. Exp. Med. , vol.202 , pp. 1575-1585
    • Vollmer, J.1    Tluk, S.2    Schmitz, C.3    Hamm, S.4    Jurk, M.5    Forsbach, A.6    Akira, S.7
  • 39
    • 0142116222 scopus 로고    scopus 로고
    • Methemoglobin is a potent activator of endothelial cells by stimulating IL-6 and IL-8 production and E-selectin membrane expression
    • Liu, X. and Spolarics, Z., Methemoglobin is a potent activator of endothelial cells by stimulating IL-6 and IL-8 production and E-selectin membrane expression. Am. J. Physiol. Cell Physiol. 2003. 285: C1036-C1046.
    • (2003) Am. J. Physiol. Cell Physiol. , vol.285
    • Liu, X.1    Spolarics, Z.2
  • 40
    • 0034161712 scopus 로고    scopus 로고
    • Hemoglobin stimulates the release of proinflammatory cytokines from leukocytes in whole blood
    • McFaul, S. J., Bowman, P. D. and Villa, V. M., Hemoglobin stimulates the release of proinflammatory cytokines from leukocytes in whole blood. J. Lab. Clin. Med. 2000. 135: 263-269.
    • (2000) J. Lab. Clin. Med. , vol.135 , pp. 263-269
    • McFaul, S.J.1    Bowman, P.D.2    Villa, V.M.3
  • 41
    • 0030734872 scopus 로고    scopus 로고
    • Heme induces the expression of adhesion molecules ICAM-1, VCAM-1, and E selectin in vascular endothelial cells
    • Wagener, F. A., Feldman, E., de Witte, T. and Abraham, N. G., Heme induces the expression of adhesion molecules ICAM-1, VCAM-1, and E selectin in vascular endothelial cells. Proc. Soc. Exp. Biol. Med. 1997. 216: 456-463.
    • (1997) Proc. Soc. Exp. Biol. Med. , vol.216 , pp. 456-463
    • Wagener, F.A.1    Feldman, E.2    de Witte, T.3    Abraham, N.G.4
  • 42
    • 70249140955 scopus 로고    scopus 로고
    • Regulation of dendritic cells and macrophages by an anti-apoptotic cell natural antibody that suppresses TLR responses and inhibits inflammatory arthritis
    • Chen, Y., Khanna, S., Goodyear, C. S., Park, Y. B., Raz, E., Thiel, S., Grönwall, C. et al., Regulation of dendritic cells and macrophages by an anti-apoptotic cell natural antibody that suppresses TLR responses and inhibits inflammatory arthritis. J. Immunol. 2009. 183: 1346-1359.
    • (2009) J. Immunol. , vol.183 , pp. 1346-1359
    • Chen, Y.1    Khanna, S.2    Goodyear, C.S.3    Park, Y.B.4    Raz, E.5    Thiel, S.6    Grönwall, C.7
  • 43
    • 34248351967 scopus 로고    scopus 로고
    • Enhancement of macrophage stimulation by lipoteichoic acid and the costimulant hemoglobin is dependent on Toll-like receptors 2 and 4
    • Cox, K. H., Ofek, I. and Hasty, D. L., Enhancement of macrophage stimulation by lipoteichoic acid and the costimulant hemoglobin is dependent on Toll-like receptors 2 and 4. Infect. Immun. 2007. 75: 2638-2641.
    • (2007) Infect. Immun. , vol.75 , pp. 2638-2641
    • Cox, K.H.1    Ofek, I.2    Hasty, D.L.3
  • 44
    • 28244445139 scopus 로고    scopus 로고
    • Evidence for multiple shared antigenic determinants within Ro60 and other lupus-related ribonucleoprotein autoantigens in human autoimmune responses
    • Pal, R., Deshmukh, U. S., Ohyama, Y., Fang, Q., Kannapell, C. C., Gaskin, F. and Fu, S. M., Evidence for multiple shared antigenic determinants within Ro60 and other lupus-related ribonucleoprotein autoantigens in human autoimmune responses. J. Immunol. 2005. 175: 7669-7677.
    • (2005) J. Immunol. , vol.175 , pp. 7669-7677
    • Pal, R.1    Deshmukh, U.S.2    Ohyama, Y.3    Fang, Q.4    Kannapell, C.C.5    Gaskin, F.6    Fu, S.M.7
  • 45
    • 0030881220 scopus 로고    scopus 로고
    • Anti-Ro fine specificity defined by multiple antigenic peptides identifies components of tertiary epitopes
    • Scofield, R. H., Zhang, F-C., Kurien, B. T. and Harley, J. B., Anti-Ro fine specificity defined by multiple antigenic peptides identifies components of tertiary epitopes. Clin. Exp. Immunol. 1997. 109: 480-487.
    • (1997) Clin. Exp. Immunol. , vol.109 , pp. 480-487
    • Scofield, R.H.1    Zhang, F.-C.2    Kurien, B.T.3    Harley, J.B.4
  • 46
    • 0019861546 scopus 로고
    • Haemoglobin binding with haptoglobin. Localization of the haptoglobin-binding site on the alpha-chain of human haemoglobin
    • Kazim, A. L. and Atassi, M. Z., Haemoglobin binding with haptoglobin. Localization of the haptoglobin-binding site on the alpha-chain of human haemoglobin. Biochem. J. 1981. 197: 507-510.
    • (1981) Biochem. J. , vol.197 , pp. 507-510
    • Kazim, A.L.1    Atassi, M.Z.2
  • 47
    • 0019765114 scopus 로고
    • Preparation of blood hemoglobins of vertebrates
    • Riggs, A., Preparation of blood hemoglobins of vertebrates. Methods Enzymol. 1981. 76: 5-29.
    • (1981) Methods Enzymol. , vol.76 , pp. 5-29
    • Riggs, A.1
  • 48
    • 33748295385 scopus 로고    scopus 로고
    • Anti-idiotype-mediated epitope spreading and diminished phagocytosis by a human monoclonal antibody recognizing late-stage apoptotic cells
    • Gandhi, R., Hussain, E., Das, J., Handa, R. and Pal, R., Anti-idiotype-mediated epitope spreading and diminished phagocytosis by a human monoclonal antibody recognizing late-stage apoptotic cells. Cell Death Differ. 2006. 13: 1715-1726.
    • (2006) Cell Death Differ. , vol.13 , pp. 1715-1726
    • Gandhi, R.1    Hussain, E.2    Das, J.3    Handa, R.4    Pal, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.