Hemoglobin stimulates the release of proinflammatory cytokines from leukocytes in whole blood

Journal of Laboratory and Clinical Medicine

Volumn 135, Issue 3, 2000, Pages 263-269

  McFaul, Steve J ^a,b   Bowman, Phil D ^a,b   Villa, Vilmar M ^a,b  

^a WALTER REED ARMY MEDICAL CENTER   (United States)

^b US ARMY INSTITUTE OF SURGICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0034161712     PISSN: 00222143     EISSN: None     Source Type: Journal    
DOI: 10.1067/mlc.2000.105180     Document Type: Article

References (65)

1. 1. Amberson WR, Mulder AG, Stegerds FR, et al. Mammalian life without blood corpuscles. Science 1933;78:106-7.
2. 2. Hamilton PB, Killer A, Van Slyke DD. Renal effects of hemoglobin infusions in dogs in hemorrhagic shock. J Exp Med 1948;86:477-87.
3. 3. Amberson WR, Jennings JJ, Rhode CM. Clinical experience with hemoglobin-saline solutions. J Appl Physiol 1949;1: 469-89.
4. 4. Rabiner SF, Helbert JR, Lopas H, Friedman LH. Evaluation of a stroma-free hemoglobin solution for use as a plasma expander. J Exp Med 1967;126:1127.
5. 5. Vandergriff KD. Blood substitutes: engineering the haemoglobin molecule. In: Tombs MP, editor. Biotechnology and genetic engineering reviews. Andover, England: Intercept Limited; 1992. p. 403-53.
6. 6. Winslow RM, editor. Hemoglobin-based red cell substitutes. Baltimore: Johns Hopkins University, 1992.
7. 7. Horowitz B, Mazur A. Oxygen equilibrium and structural studies of amidinated human hemoglobin. In: Jamieson GA, Greenwalt TJ, editors. Blood substitutes and plasma expanders. New York: Alan R. Liss; 1978. p. 149-65.
8. 8. Somers M, Piqueras AI, Strange K, Zeidel ML, Pfaller W, Gawryl M, et al. Interactions of ultrapure bovine hemoglobin with renal epithelial cells in vivo and in vitro. Am J Physiol 1997;279:F38-52.
9. 9. Smith CD, Schuschereba ST, Hess JR, McKinney L, Bunch D, Bowman PD. Liver and kidney injury after administration of hemoglobin cross-linked with (bis)3,5-dibromosalicyl fumarate. Biomat Artif Cells Artif Organs 1990;18:251-61.
10. 10. Regan RF, Panter SS. Neurotoxicity of hemoglobin in cortical cell culture. Neurosci Lett 1993;153:219-22.
11. 11. White CT, Murray AJ, Greene JR, Smith DJ, Medina F, Makovec GT, et al. Toxicity of human hemoglobin solution infused into rabbits. J Lab Clin Med 1986;108:121-31.
12. 12. Smith DJ, Winslow RM. Effects of extraerythrocytic hemoglobin and its components on mononuclear cell procoagulant activity. J Lab Clin Med 1992;119:176-82.
13. 13. McFaul SJ, Bowman PD, Villa VM, Gutierrez-Ibanez MJ, Johnson M, Smith D. Hemoglobin stimulates mononuclear leukocytes to release interleukin-8 and tumor necrosis factor-α. Blood 1994;84:3175-81.
14. 14. Hess JR, Macdonald VW, Brinkley WW. Systemic and pulmonary hypertension after resuscitation with cell-free hemoglobin. J Appl Physiol 1993;74:1769-78.
15. 15. Kasper SM, Walter M, Grune F, Bischoff A, Erasmi H, Buzello W. Effects of a hemoglobin-based oxygen carrier (HBOC-201) on hemodynamics and oxygen transport in patients undergoing preoperative hemodilution for elective abdominal aortic surgery. Cardiovasc Anesth 1996;83:921-7.
16. 16. Beny JL, Brunet PC, Van der Bent V. Hemoglobin causes both endothelium-dependent and endothelium-independent contraction of the pig coronary ateries, independently of an inhibition of EDRF effects. Experientia 1989;45:132-4.
17. 17. Krishnamurti C, Carter AJ, Maglawsang P, Hess JR, Cutting MA, Alving BM. Cardiovascular toxicity of human cross-linked hemoglobin in a rabbit endotoxemia model. Crit Care Med 1997;25:1874-80.
18. 18. Su D, Roth RI, Yoshida M, Levin J. Hemoglobin increases mortality from bacterial endotoxin. Infect Immun 1997;65:1258-66.
19. 19. Benesch RE, Benesch R, Renthal RD, Maeda N. Affinity labeling of the polyphosphate binding site of hemoglobin. Biochemistry 1972;11:3576-82.
20. 20. Benesch R, Benesch RE. Preparation and properties of hemoglobin modified with derivatives of pyridoxal. Methods Enzymol 1981;76:147-59.
21. 21. Benesch RE, Kwong S. The stability of the heme-globin linkage in some normal, mutant, and chemically modified hemoglobins. J Biol Chem 1990;265:881-5.
22. 2). J Biol Chem 1986;261:929-37.
23. 23. Hess JR, Winslow RM. Red cell substitutes. In: Anderson KC, Nelss PM, editors. Scientific basis of transfusion medicine: implications for clinical practice. Philadelphia: WB Saunders; 1994. p. 815-29.
24. 24. Sehgal LR, Rosen AL, Gould SA, Sehgal HL, Moss GS. Preparation and in vitro chacteristics of polymerized pyridoxylated hemoglobin. Transfusion 1983;23:158-62.
25. 25. Keipert PE, Verosky M, Triner L. Plasma retention and metabolic fate of hemoglobin modified with an interdimeric covalent cross link. ASAIO Trans 1989;35:153-9.
26. 26. Keipert PE, Gomez CL, Gonzales A, Macdonald VW, Hess JR, Winslow RM. Diaspirin cross-linked hemoglobin: tissue distribution and long-term excretion after exchange transfusion. J Lab Clin Med 1994;123:701-11.
27. 27. Kim HW, Greenburg AG. Ferrous hemoglobin scavenging of endothelium derived nitric oxide is a principal mechanism for hemoglobin mediated vasoactivities in isolated rat thoracic aorta. Artif Cells Blood Substit Immobil Biotechnol 1997;25:121-33.
28. 28. Loscalzo J. Nitric oxide binding and the adverse effects of cell-free hemoglobins: what makes us different from earthworms. J Lab Clin Med 1997;129:580-3.
29. 29. Sanders KE, Ackers G, Sligor S. Engineering and design of blood substitutes. Curr Opin Struct Biol 1996;6:534-40.
30. 30. Vollrath BAM, Weir BKA, Macdonald RL, Cook DA. Intracellular mechanism involved in the responses of cerebrovascular smooth muscle cells to hemoglobin. J Neurosurg 1994;80:261-8.
31. 31. Macdonald RL, Weir KA. A review of hemoglobin and the pathogenesis of cerebral vasospasm. Stroke 1991;22:971-82.
32. 32. Vollrath B, Weir KA, Cook DA. Hemoglobin causes release of inositol trisphosphate from vascular smooth muscle. Biochem Biophys Res Commun 1990;171:506-11.
33. 33. Darbonne WC, Rice GC, Mohler MA, Apple T, Hebert CA, Valente AJ, et al. Red blood cells are a sink for interleukin-8, a leukocyte chemotaxin. J Clin Invest 1991;88:1362-9.
34. 34. DeForge LE, Preston AM, Takeuchi E, Kenney J, Boxer LA, Remick DG. Regulation of interleukin-8 gene expression by oxidant stress. J Biol Chem 1993;268:568-76.
35. 35. DeForge LE, Fantone JC, Kenney JS, Remick DG. Oxygen radical scavengers selectively inhibit interleukin-8 production in human whole blood. J Clin Invest 1990;90:123-9.
36. 36. Winslow RM, Chapman KW. Pilot-scale preparation of hemoglobin solutions. In: Everse J, Vandegriff KD, Winslow RM, editors. Methods in enzymology (vol 231). San Diego: Academic Press; 1994. p. 3-16.
37. 37. McFaul SJ, Bowman PD. Quantitation of polymorphonuclear leukocyte adherence to endothelial cells by electronic particle size discrimination. J Immunol Methods 1990;130: 171-6.
38. 38. Valles J, Santos MT, Marcus AJ, Safier LB, Broekman MJ, Islam N, et al. Downregulation of human platelet reactivity by neutrophils. J Clin Invest 1993;92:1357-65.
39. 39. Marcus AJ. Thrombosis and inflammation as multicellular processes: significance of cell-cell interactions. Semin Hematol 1994;31:261-9.
40. 40. Lorenzet R, Niemetz J, Marcus AJ, Broekman MJ. Enhancement of mononuclear procoagulant activity by platelet 12-hydroxyeicosatetraenoic acid. J Clin Invest 1986;78:418-23.
41. 41. Lukacs NW, Strieter RM, Elner V, Evanoff HL, Burdick MD, Kunkel SL. Production of chemokines, interleukin-8 and moncyte chemoattractant protein-1, during monocyte: endothelial cell interactions. Blood 1995;86:2767-73.
42. 42. Steinhauser ML, Kunkel SL, Hogaboam CM, Evanoff H, Strieter RM, Lukacs NW. Macrophage/fibroblast coculture induces macrophage inflammatory protein-1 α production mediated by intercellular adhesion molecule-1 and oxygen radicals. J Leukoc Biol 1998;64:636-41.
43. 43. Forslid J, Hallden G, Hed J. The inhibition of CR1 mobilization of human granulocytes by the presence of erythrocytes. A possible mechanism for intravascular regulation of granulocyte modulation. Immunol 1991;74:685-8.
44. 44. Alberts B, Bray D, Lewis J, Raff M, Roberts K, Watson JD, editors. Molecular biology of the cell. 2nd ed. New York and London: Garlan Publishing; 1989. p. 976.
45. 45. Lumadue JA, Lanzkron SM, Kennedy SD, Kuhl DT, Kickler TS. Cytokine induction of platelet activation. Am J Clin Pathol 1996;106:795-8.
46. 46. Weyrich AS, Elstad MR, McEver RP, McIntyre TM, Moore KL, Morrissey JH, et al. Activated platelets signal chemokine synthesis by human monocytes. J Clin Invest 1996;97:1525-34.
47. 47. Takeuchi K, Higuchi T, Yamashita T, Koike K. Chemokine production by human megakaryocytes derived from cd34-positive cord blood cells. Cytokine 1999;11:424-34.
48. 48. Piccardoni P, Evangelista V, Piccoli A, de Gaetano G, Walz A, Cerletti C. Thromb Haemost 1996;76:780-5.
49. 49. Silliman CC, Voelkel NF, Allard JD, Elzi DJ, Turder RM, Johnson JL. Plasma and lipids from stored packed red blood cells cause acute lung injury in an animal model. J Clin Invest 1998;101:1458-67.
50. 50. Hess JR. Blood substitutes for surgery and trauma: efficacy and toxicity issues. 1999;12:81-90.
51. 51. Avall A, Hyllner M, Bengtson JP, Carlsson L, Bengtsson A. Postoperative inflammatory response after autologous and allogeneic blood transfusion. Anesthesiology 1997;87:511-6.
52. 52. Heiss MM, Mempel W, Jauch KW, Delanoff C, Mayer G, Mempel M, et al. Beneficial effect of autologous blood transfusion on inffectious complications after colorectal cancer surgery. Lancet 1993;342:1328-33.
53. 53. Mezrow CK, Bergstein I, Tartter PI. Postoperative infections following autologous and homologous blood transfusions. Transfusion 1992;32:27-30.
54. 54. Murphy P, Heal JM, Blumberg N. Infection or suspected infection after hip replacement surgery with autologous or homologous blood transfusions. Transfusion 1991;31:212-7.
55. 55. Blumberg N, Heal JM. Transfusion and recipient immune function. Arch Pathol Lab Med 1989;113:246-53.
56. 56. Sewell WA, Scurr LL, Orphanides H, Kinder S, Ludowyke RT. Induction of interleukin-4 and interleukin-5 expression in mast cells is inhibited by glucocorticoids. Clin Diagn Lab Immunol 1998;5:18-23.
57. 57. Beetz A, Messer G, Oppel T, van Beuningen D, Peter RU, Kind P. Induction of interleukin-6 by ionizing radiation in a human epithelial cell line: control by corticosteroids. Int J Radiat Biol 1997;72:33-43.
58. 58. Chaudhary LR, Avioli LV. Regulation of interleukin-8 gene expression by interleukin-1 beta, osteotropic hormones, and protein kinase inhibitors in normal human bone marrow stromal cells. J Biol Chem 1996;271:591-6.
59. 59. Arzt E, Sauer J, Pollmacher T, Labeur M, Holsboeer F, Reul JM, et al. Glucocorticoids suppress interleukin-1 receptor antagonist synthesis following induction by endotoxin. Endocrinology 1994;134:672-7.
60. 60. Albanesi C, Pastore S, Fanales-Belasio E, Girolomoni G. Cetirizine and hydrocortisone differentially regulate ICAM-1 expression and chemokine release in cultured human keratinocytes. Clin Exp Allergy 1998;28:101-9.
61. 61. Myranasu M, Misake Y, Izumi S, Takaishi T, Morita Y, Nakamura H, et al. Glucocorticoids inhibit chemokine generation by human eosinophils. J Allergy Clin Immunol 1998;101:75-83.
62. 62. Van der Poll T, Lowry SF. Lipopolysaccharide-induced interleukin-8 production by human whole blood is enhanced by epinephrine and inhited by hydrocortisone. 1997;65:378-81.
63. 63. Cunha FQ, Ferreira SH. The release of a neutrophil chemotactic factor from peritoneal macrophages by endotoxin: inhibition by glucocorticoids. Eur J Pharmacol 1986;129:65-76.
64. 64. Deleuran B, Kristensen M, Paludan K, Zachariae C, Larsen CG, Zachariae E, et al. The effect of second-line antirheumatic drugs on interleukin-8 mRNA synthesis and protein secretion in human endothelial cells. Cytokine 1992;4:403-9.
65. 65. Yamada K, Takane-Gyotoku N, Inada C, Nonaka K. Endogenous tumor necrosis factor alpha production by a pancreatic beta-cell line: inhibitory effects of hydrocortisone and nicotinamide. Life Sci 1996;59:423-9.