Low dose CT of the heart: A quantum leap into a new era of cardiovascular imaging;La TC del cuore a bassa dose: un salto epocale nella nuova era dell'imaging cardiovascolare

Radiologia Medica

Volumn 115, Issue 8, 2010, Pages 1179-1207

  Maffei, E ^a   Martini, C ^a,b   De Crescenzo, S ^c   Arcadi, T ^a   Clemente, A ^a   Capuano, E ^a,b   Rossi, A ^b   Malago R ^d   Mollet, N ^b   Weustink, A ^b   Tedeschi, C ^e   La Grutta, L ^f   Seitun, S ^g   Igoren Guaricci, A ^h   Cademartiri, F ^a,b  

^a UNIVERSITY HOSPITAL OF PARMA   (Italy)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c OSPEDALE NIGUARDA CA GRANDA   (Italy)

^d UNIVERSITY OF VERONA   (Italy)

^e San Gennaro Hospital   (Italy)

^f UNIVERSITY OF PALERMO   (Italy)

^g UNIVERSITY OF GENOA   (Italy)

^h UNIVERSITY OF FOGGIA   (Italy)

Author keywords

Computed tomography coronary angiography; Conventional coronary angiography; Coronary artery disease; Radiation dose; Training

Indexed keywords

ANGIOCARDIOGRAPHY; CARDIOLOGY; COMPUTER ASSISTED TOMOGRAPHY; CORONARY ARTERY DISEASE; DEVICE SAFETY; EDUCATION; HUMAN; RADIATION DOSE; RADIOGRAPHY; RADIOLOGY; REVIEW;

CARDIOLOGY; CORONARY ANGIOGRAPHY; CORONARY DISEASE; EQUIPMENT SAFETY; HUMANS; RADIATION DOSAGE; RADIOLOGY; TOMOGRAPHY, X-RAY COMPUTED;

EID: 78751706539     PISSN: 00338362     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11547-010-0566-4     Document Type: Article

References (79)

1. F. Cademartiri G. Runza M. Belgrano, et al. 2005 Introduction to coronary imaging with 64-slice computed tomography Radiol Med (Torino) 110 16 41 (Pubitemid 41415967)
2. K. Nieman M. Oudkerk B.J. Rensig, et al. 2001 Coronary angiography with multislice computed tomography Lancet 357 599 603 1:STN:280: DC%2BD3MrhtV2mtw%3D%3D 10.1016/S0140-6736(00)04058-7 11558487 (Pubitemid 32179614)
3. W.P. Shuman K.R. Branch J.M. May, et al. 2008 Prospective versus retrospective ECG gating for 64-detector CT of the coronary arteries: comparison of image quality and patient radiation dose Radiology 248 431 437 10.1148/radiol.2482072192 18552312
4. F. Pugliese N.R. Mollet M.G. Hunink, et al. 2008 Diagnostic performance of coronary CT angiography by using different generations of multisection scanners: single-center experience Radiology 246 384 393 10.1148/radiol. 2462070113 18180337
5. R.C. Hendel M.R. Patel C.M. Kramer, et al. 2006 ACCF/ACR/SCCT/SCMR/ASNC/ NAS CI/SCAI/SIR 2006 appropriateness criteria for cardiac computed tomography and cardiac magnetic resonance imaging: a report of the American College of Cardiology Foundation Quality Strategic Directions Committee Appropriateness Criteria Working Group, American College of Radiology, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, American Society of Nuclear Cardiology, North American Society for Cardiac Imaging, Society for Cardiovascular Angiography and Interventions, and Society of Interventional Radiology J Am Coll Cardiol 48 1475 1497 10.1016/j.jacc.2006.07. 003 17010819
6. D.A. Bluemke S. Achenbach M. Budoff, et al. 2008 Noninvasive coronary artery imaging: magnetic resonance angiography and multidetector computed tomography angiography: a scientific statement from the american heart association committee on cardiovascular imaging and intervention of the council on cardiovascular radiology and intervention, and the councils on clinical cardiology and cardiovascular disease in the young Circulation 118 586 606 10.1161/CIRCULATIONAHA.108.189695 18586979
7. S. Schroeder S. Achenbach F. Bengel, et al. 2008 Cardiac computed tomography: indications, applications, limitations, and training requirements: report of a Writing Group deployed by the Working Group Nuclear Cardiology and Cardiac CT of the European Society of Cardiology and the European Council of Nuclear Cardiology Eur Heart J 29 531 556 10.1093/eurheartj/ehm544 18084017 (Pubitemid 351264173)
8. K. Fox M.A. Garcia D. Ardissino, et al. 2006 Guidelines on the management of stable angina pectoris: executive summary: the Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology Eur Heart J 27 1341 1381 10.1093/eurheartj/ehl001 16735367 (Pubitemid 43998110)
9. G.L. Di Tanna E. Berti E. Stivanello, et al. 2008 Informative value of clinical research on multislice computed tomography in the diagnosis of coronary artery disease: a systematic review Int J Cardiol 130 386 404 10.1016/j.ijcard.2008.06.032 18760849
10. G. Mowatt J.A. Cook G.S. Hillis, et al. 2008 64-Slice computed tomography angiography in the diagnosis and assessment of coronary artery disease: systematic review and meta-analysis Heart 94 1386 1393 1:STN:280: DC%2BD1cnmvVyisw%3D%3D 10.1136/hrt.2008.145292 18669550
11. G. Mowatt E. Cummins N. Waugh, et al. 2008 Systematic review of the clinical effectiveness and cost-effectiveness of 64-slice or higher computed tomography angiography as an alternative to invasive coronary angiography in the investigation of coronary artery disease Health Technol Assess 12 iii iv 1:STN:280:DC%2BD1czgtVOmtw%3D%3D
12. J.M. Miller C.E. Rochitte M. Dewey, et al. 2008 Diagnostic performance of coronary angiography by 64-row CT N Engl J Med 359 2324 2336 1:CAS:528:DC%2BD1cXhsVehtbjN 10.1056/NEJMoa0806576 19038879
13. J.M. Miller M. Dewey A.L. Vavere, et al. 2008 Coronary CT angiography using 64 detector rows: methods and design of the multi-centre trial CORE-64 Eur Radiol 19 816 828 10.1007/s00330-008-1203-7 18998142
14. M.J. Budoff D. Dowe J.G. Jollis, et al. 2008 Diagnostic performance of 64- multidetector row coronary computed tomographic angiography for evaluation of coronary artery stenosis in individuals without known coronary artery disease: results from the prospective multicenter ACCURACY (Assessment by Coronary Computed Tomographic Angiography of Individuals Undergoing Invasive Coronary Angiography) trial J Am Coll Cardiol 52 1724 1732 10.1016/j.jacc.2008. 07.031 19007693
15. R. Marano F. De Cobelli I. Floriani, et al. 2009 Italian multicenter, prospective study to evaluate the negative predictive value of 16- and 64-slice MDCT imaging in patients scheduled for coronary angiography (NIMISCAD-Non Invasive Multicenter Italian Study for Coronary Artery Disease) Eur Radiol 19 1114 1123 10.1007/s00330-008-1239-8 19089430
16. R. Malago M. D'Onofrio I. Baglio, et al. 2009 Choice strategy of different dose-saving protocols in 64-slice MDCT coronary angiography Radiol Med 114 1196 1213 1:STN:280:DC%2BC3c%2FjsVCqtg%3D%3D 10.1007/s11547-009-0432-4 19669112
17. Maffei E, Palumbo AA, Martini C et al (2009) "In-house" pharmacological management for computed tomography coronary angiography: heart rate reduction, timing and safety of different drugs used during patient preparation. Eur Radiol, in press
18. A.A. Palumbo E. Maffei C. Martini, et al. 2009 Coronary calcium score as gatekeeper for 64-slice computed tomography coronary angiography in patients with chest pain: per-segment and per-patient analysis Eur Radiol 19 2127 2135 10.1007/s00330-009-1398-2 19387651
19. R.F. Redberg J. Walsh 2008 Pay now, benefits may follow-the case of cardiac computed tomographic angiography N Engl J Med 359 2309 2311 1:CAS:528:DC%2BD1cXhsVehtbzI 10.1056/NEJMp0805920 19038877
20. P.S. Douglas R.F. Redberg R.S. Blumenthal, et al. 2008 Imaging for coronary risk assessment: ready for prime time? JACC Cardiovasc Imaging 1 263 265 10.1016/j.jcmg.2008.01.003 19356436 (Pubitemid 351445404)
21. P. Stolzmann S. Leschka H. Scheffel, et al. 2008 Dual-source CT in step-andshoot mode: noninvasive coronary angiography with low radiation dose Radiology 249 71 80 10.1148/radiol.2483072032 18796669
22. A.C. Weustink N.R. Mollet L.A. Neefjes, et al. 2009 Preserved diagnostic performance of dual-source CT coronary angiography with reduced radiation exposure and cancer risk Radiology 252 53 60 10.1148/radiol.2521082023 19451542
23. A.C. Weustink N.R. Mollet F. Pugliese, et al. 2008 Optimal electrocardiographic pulsing windows and heart rate: effect on image quality and radiation exposure at dual-source coronary CT angiography Radiology 248 792 798 10.1148/radiol.2483072098 18710975
24. J.K. Min R.V. Swaminathan M. Vass, et al. 2009 High-definition multidetector computed tomography for evaluation of coronary artery stents: comparison to standard-definition 64-detector row computed tomography J Cardiovasc Comput Tomogr 3 246 251 10.1016/j.jcct.2009.06.006 19577213
25. P.A. Hein V.C. Romano A. Lembcke, et al. 2009 Initial experience with a chest pain protocol using 320-slice volume MDCT Eur Radiol 19 1148 1155 10.1007/s00330-008-1255-8 19137311
26. A. Lembcke P.A. Hein A.C. Borges, et al. 2009 One-stop-shop cardiac diagnosis in a single heart beat using 320-slice computed tomography: ascending aortic aneurysm, hypertrophic cardiomyopathy and mixed valvular heart disease Eur J Cardiothorac Surg 35 726 10.1016/j.ejcts.2008.12.012 19233680
27. M.L. Steigner H.J. Otero T. Cai, et al. 2009 Narrowing the phase window width in prospectively ECG-gated single heart beat 320-detector row coronary CT angiography Int J Cardiovasc Imaging 25 85 90 10.1007/s10554-008-9347-8 18663599
28. F.J. Rybicki H.J. Otero M.L. Steigner, et al. 2008 Initial evaluation of coronary images from 320-detector row computed tomography Int J Cardiovasc Imaging 24 535 546 10.1007/s10554-008-9308-2 18368512
29. J. Hausleiter B. Bischoff F. Hein, et al. 2009 Feasibility of dual-source cardiac CT angiography with high-pitch scan protocols J Cardiovasc Comput Tomogr 3 236 242 10.1016/j.jcct.2009.05.012 19577211
30. S. Achenbach M. Marwan T. Schepis, et al. 2009 High-pitch spiral acquisition: a new scan mode for coronary CT angiography J Cardiovasc Comput Tomogr 3 117 121 10.1016/j.jcct.2009.02.008 19332343
31. F. Cademartiri 2009 Cardiac CT: the missing piece of the puzzle Eur Radiol 19 2584 2585 1:STN:280:DC%2BD1MjgtFSqsg%3D%3D 10.1007/s00330-009-1564-6 19760419
32. M. Lell M. Marwan T. Schepis, et al. 2009 Prospectively ECG-triggered high-pitch spiral acquisition for coronary CT angiography using dual source CT: technique and initial experience Eur Radiol 19 2576 2583 10.1007/s00330-009- 1558-4 19760421
33. E.P. Efstathopoulos N.L. Kelekis I. Pantos, et al. 2009 Reduction of the estimated radiation dose and associated patient risk with prospective ECG-gated 256-slice CT coronary angiography Phys Med Biol 54 5209 5222 1:STN:280:DC%2BD1MrmtVehtg%3D%3D 10.1088/0031-9155/54/17/009 19671974
34. D.M. Bardo J. Asamato C.S. Mackay, et al. 2009 Low-dose coronary artery computed tomography angiogram of an infant with tetralogy of fallot using a 256-slice multidetector computed tomography scanner Pediatr Cardiol 30 824 826 10.1007/s00246-009-9389-2 19214622
35. J. Hausleiter T. Meyer F. Hermann, et al. 2009 Estimated radiation dose associated with cardiac CT angiography Jama 301 500 507 1:CAS:528: DC%2BD1MXhtlyksbk%3D 10.1001/jama.2009.54 19190314
36. T.F. Jakobs C.R. Becker B. Ohnesorge, et al. 2002 Multislice helical CT of the heart with retrospective ECG gating: reduction of radiation exposure by ECG-controlled tube current modulation Eur Radiol 12 1081 1086 10.1007/s00330-001-1278-x 11976849 (Pubitemid 36940173)
37. M. Francone A. Napoli I. Carbone, et al. 2007 Noninvasive imaging of the coronary arteries using a 64-row multidetector CT scanner: initial clinical experience and radiation dose concerns Radiol Med 112 31 46 1:STN:280: DC%2BD2s7lsVCjtg%3D%3D 10.1007/s11547-007-0118-8 17310293 (Pubitemid 46360871)
38. Feuchtner GM, Jodocy D, Klauser A et al (2009) Radiation dose reduction by using 100-kV tube voltage in cardiac 64-slice computed tomography: a comparative study. Eur J Radiol, in press
39. B. Bischoff F. Hein T. Meyer, et al. 2009 Impact of a reduced tube voltage on CT angiography and radiation dose: results of the PROTECTION I study JACC Cardiovasc Imaging 2 940 946 10.1016/j.jcmg.2009.02.015 19679281
40. H. Scheffel H. Alkadhi S. Leschka, et al. 2008 Low-dose CT coronary angiography in the step-and-shoot mode: diagnostic performance Heart 94 1132 1137 1:STN:280:DC%2BD1crhvVersA%3D%3D 10.1136/hrt.2008.149971 18519548
41. N. Hirai J. Horiguchi C. Fujioka, et al. 2008 Prospective versus retrospective ECG-gated 64-detector coronary CT angiography: assessment of image quality, stenosis, and radiation dose Radiology 248 424 430 10.1148/radiol.2482071804 18574140
42. G. Pontone D. Andreini A.L. Bartorelli, et al. 2009 Diagnostic accuracy of coronary computed tomography angiography: a comparison between prospective and retrospective electrocardiogram triggering J Am Coll Cardiol 54 346 355 10.1016/j.jacc.2009.04.027 19608033
43. D. Ertel M.M. Lell F. Harig, et al. 2009 Cardiac spiral dual-source CT with high pitch: a feasibility study Eur Radiol 19 2357 2362 10.1007/s00330-009-1503-6 19565245
44. S.N. Penfold A.B. Rosenfeld R.W. Schulte, et al. 2009 A more accurate reconstruction system matrix for quantitative proton computed tomography Med Phys 36 4511 4518 1:CAS:528:DC%2BD1MXht1WhsrzK 10.1118/1.3218759 19928082
45. A.J. Einstein J. Sanz S. Dellegrottaglie, et al. 2008 Radiation dose and cancer risk estimates in 16-slice computed tomography coronary angiography J Nucl Cardiol 15 232 240 10.1016/j.nuclcard.2007.09.028 18371595 (Pubitemid 351396314)
46. B.A. Herzog C.A. Wyss L. Husmann, et al. 2009 First head-to-head comparison of effective radiation dose from low-dose CT with prospective ECG-triggering versus invasive coronary angiography Heart 95 1656 1661 1:STN:280:DC%2BD1Mnlt1Cksw%3D%3D 10.1136/hrt.2008.162420 19581273
47. G.L. Raff K.M. Chinnaiyan D.A. Share, et al. 2009 Radiation dose from cardiac computed tomography before and after implementation of radiation dosereduction techniques Jama 301 2340 2348 1:CAS:528:DC%2BD1MXntFCms70%3D 10.1001/jama.2009.814 19509381
48. UNSCEAR (2000) United Nations Scientific Committee on the effects of atomic radiation - 2000 Report, Medical radiation exposures. Annex D. UNSCEAR
49. ICRP-103 (2007) The 2007 Recommendations of the International Commission on Radiological Protection. International Commission on Radiological Protection
50. H. von Boetticher J. Lachmund W. Hoffmann 2008 Effective dose estimation in diagnostic radiology with two dosimeters: impact of the 2007 recommendations of the ICRP Health Phys 95 337 340 10.1097/01.HP.0000318877.79131.08
51. Matsubara K, Koshida K, Suzuki M et al (2009) Effective dose evaluation of multidetector CT examinations: influence of the ICRP recommendation in 2007. Eur Radiol, in press
52. o 154
53. M. Tubiana L.E. Feinendegen C. Yang, et al. 2009 The linear no-threshold relationship is inconsistent with radiation biologic and experimental data Radiology 251 13 22 10.1148/radiol.2511080671 19332842
54. M.P. Little R. Wakeford E.J. Tawn, et al. 2009 Risks associated with low doses and low dose rates of ionizing radiation: why linearity may be (almost) the best we can do Radiology 251 6 12 10.1148/radiol.2511081686 19332841
55. M.S. Lauer 2009 Elements of danger - the case of medical imaging N Engl J Med 361 841 843 1:CAS:528:DC%2BD1MXhtVKht7bP 10.1056/NEJMp0904735 19710480
56. R. Fazel H.M. Krumholz Y. Wang, et al. 2009 Exposure to low-dose ionizing radiation from medical imaging procedures N Engl J Med 361 849 857 1:CAS:528:DC%2BD1MXhtVKhtL7M 10.1056/NEJMoa0901249 19710483
57. F. Stacul D. Sironi G. Grisi, et al. 2009 64-Slice CT coronary angiography versus conventional coronary angiography: activity-based cost analysis Radiol Med 114 239 252 1:STN:280:DC%2BD1MzktFOktg%3D%3D 10.1007/s11547-009-0376-8 19266257
58. J.K. Min N. Kang L.J. Shaw, et al. 2008 Costs and clinical outcomes after coronary multidetector CT angiography in patients without known coronary artery disease: comparison to myocardial perfusion SPECT Radiology 249 62 70 10.1148/radiol.2483071453 18796668
59. J.K. Min L.J. Shaw D.S. Berman, et al. 2008 Costs and clinical outcomes in individuals without known coronary artery disease undergoing coronary computed tomographic angiography from an analysis of Medicare category III transaction codes Am J Cardiol 102 672 678 10.1016/j.amjcard.2008.04.045 18773986
60. J.K. Min L.J. Shaw D.S. Berman 2008 Cost-effective applications of cardiac computed tomography in coronary artery disease Expert Rev Cardiovasc Ther 6 43 55 10.1586/14779072.6.1.43 18095906
61. J.K. Min M. Robinson L.J. Shaw, et al. 2008 Differences in episode-based care costs for multidetector computed tomographic coronary angiography versus myocardial perfusion imaging for the diagnosis of coronary artery disease J Med Econ 11 327 340 19450089
62. R.K. Khare D.M. Courtney E.S. Powell, et al. 2008 Sixty-four-slice computed tomography of the coronary arteries: cost-effectiveness analysis of patients presenting to the emergency department with low-risk chest pain Acad Emerg Med 15 623 632 10.1111/j.1553-2712.2008.00161.x 19086322
63. M. Dewey B. Hamm 2007 Cost effectiveness of coronary angiography and calcium scoring using CT and stress MRI for diagnosis of coronary artery disease Eur Radiol 17 1301 1309 10.1007/s00330-006-0439-3 17031453 (Pubitemid 46691961)
64. J.A. Ladapo U. Hoffmann F. Bamberg, et al. 2008 Cost-effectiveness of coronary MDCT in the triage of patients with acute chest pain AJR Am J Roentgenol 191 455 463 10.2214/AJR.07.3611 18647917
65. F. Pugliese M.G. Hunink K. Gruszczynska, et al. 2009 Learning curve for coronary CT angiography: what constitutes sufficient training? Radiology 251 359 368 10.1148/radiol.2512080384 19401570
66. C. van Kuijk J.L. Grashuis J.C. Steenbeek, et al. 1990 Evaluation of postprocessing dual-energy methods in quantitative computed tomography. Part 2. Practical aspects Invest Radiol 25 882 889 10.1097/00004424-199008000-00003 2394570 (Pubitemid 20226822)
67. T. Baks F. Cademartiri A.D. Moelker, et al. 2006 Multislice computed tomography and magnetic resonance imaging for the assessment of reperfused acute myocardial infarction J Am Coll Cardiol 48 144 152 10.1016/j.jacc.2006.02.059 16814660 (Pubitemid 43929221)
68. F. Hyafil J.C. Cornily J.H. Rudd, et al. 2009 Quantification of inflammation within rabbit atherosclerotic plaques using the macrophage-specific CT contrast agent N1177: a comparison with 18F-FDG PET/CT and histology J Nucl Med 50 959 965 1:CAS:528:DC%2BD1MXnvF2ru7o%3D 10.2967/jnumed.108.060749 19443582
69. R.T. George C. Silva M.A. Cordeiro, et al. 2006 Multidetector computed tomography myocardial perfusion imaging during adenosine stress J Am Coll Cardiol 48 153 160 10.1016/j.jacc.2006.04.014 16814661 (Pubitemid 43929222)
70. J.A. Goldstein M.J. Gallagher W.W. O'Neill, et al. 2007 A randomized controlled trial of multi-slice coronary computed tomography for evaluation of acute chest pain J Am Coll Cardiol 49 863 871 10.1016/j.jacc.2006.08.064 17320744 (Pubitemid 46275355)
71. M. Naghavi E. Falk H.S. Hecht, et al. 2006 From vulnerable plaque to vulnerable patient-Part III: Executive summary of the Screening for Heart Attack Prevention and Education (SHAPE) Task Force report Am J Cardiol 98 2H 15H 10.1016/j.amjcard.2006.03.002 16843744 (Pubitemid 44523760)
72. G. Pundziute J.D. Schuijf J.W. Jukema, et al. 2007 Prognostic value of multislice computed tomography coronary angiography in patients with known or suspected coronary artery disease J Am Coll Cardiol 49 62 70 10.1016/j.jacc.2006.07.070 17207724 (Pubitemid 46026899)
73. J.K. Min L.J. Shaw R.B. Devereux, et al. 2007 Prognostic value of multidetector coronary computed tomographic angiography for prediction of all-cause mortality J Am Coll Cardiol 50 1161 1170 10.1016/j.jacc.2007.03.067 17868808 (Pubitemid 47375010)
74. A. Aldrovandi E. Maffei A. Palumbo, et al. 2009 Prognostic value of computed tomography coronary angiography in patients with suspected coronary artery disease: a 24-month follow-up study Eur Radiol 19 1653 1660 10.1007/s00330-009-1344-3 19224218
75. F. Cademartiri S. Seitun M. Romano, et al. 2008 Prognostic value of 64-slice coronary angiography in diabetes mellitus patients with known or suspected coronary artery disease compared with a nondiabetic population Radiol Med 113 627 643 1:STN:280:DC%2BD1critFSitQ%3D%3D 10.1007/s11547-008-0268-3 18478189
76. J.M. van Werkhoven J.D. Schuijf O. Gaemperli, et al. 2009 Incremental prognostic value of multi-slice computed tomography coronary angiography over coronary artery calcium scoring in patients with suspected coronary artery disease Eur Heart J 30 2622 2629 10.1093/eurheartj/ehp272 19567382
77. O. Gaemperli I. Valenta T. Schepis, et al. 2008 Coronary 64-slice CT angiography predicts outcome in patients with known or suspected coronary artery disease Eur Radiol 18 1162 1173 10.1007/s00330-008-0871-7 18286291
78. O. Gaemperli P.A. Kaufmann 2008 Hybrid cardiac imaging: more than the sum of its parts? J Nucl Cardiol 15 123 126 10.1016/j.nuclcard.2007.12.002 18242489 (Pubitemid 351168526)
79. D.S. Berman R. Hachamovitch L.J. Shaw, et al. 2006 Roles of nuclear cardiology, cardiac computed tomography, and cardiac magnetic resonance: Noninvasive risk stratification and a conceptual framework for the selection of noninvasive imaging tests in patients with known or suspected coronary artery disease J Nucl Med 47 1107 1118 16818945