-
1
-
-
28544442309
-
Random chemistry as a new tool for the generation of small compound libraries: development of a new acetylcholinesterase inhibitor
-
Kapkovà P., Heller E., Unger M., Folkers G., Holzgrabe U. Random chemistry as a new tool for the generation of small compound libraries: development of a new acetylcholinesterase inhibitor. J. Med. Chem. 2005, 48:7496-7499.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 7496-7499
-
-
Kapkovà, P.1
Heller, E.2
Unger, M.3
Folkers, G.4
Holzgrabe, U.5
-
3
-
-
33749576309
-
Random chemistry as a new tool for the generation of small-compound libraries
-
Kapkovà P., Heller E., Kugelmann E., Faber J., Bringmann G., Kessler U., Folkers G., Holzgrabe U. Random chemistry as a new tool for the generation of small-compound libraries. Arch. Pharm. (Weinheim) 2006, 339:489-497.
-
(2006)
Arch. Pharm. (Weinheim)
, vol.339
, pp. 489-497
-
-
Kapkovà, P.1
Heller, E.2
Kugelmann, E.3
Faber, J.4
Bringmann, G.5
Kessler, U.6
Folkers, G.7
Holzgrabe, U.8
-
4
-
-
46249123437
-
Generation of small-compound libraries via random chemistry by Fenton's reagent
-
Kugelmann E., Holzgrabe U. Generation of small-compound libraries via random chemistry by Fenton's reagent. Arkivoc 2008, 11:247-255.
-
(2008)
Arkivoc
, vol.11
, pp. 247-255
-
-
Kugelmann, E.1
Holzgrabe, U.2
-
5
-
-
0025019482
-
On the structure of the dioncophyllaceae alkaloids dioncophylline A " triphyophylline" and " O-methyl-triphyophylline"
-
Bringmann G., Rübenacker M., Jansen J.R., Scheutzow D. On the structure of the dioncophyllaceae alkaloids dioncophylline A " triphyophylline" and " O-methyl-triphyophylline" Tetrahedron Lett. 1990, 31:639-642.
-
(1990)
Tetrahedron Lett.
, vol.31
, pp. 639-642
-
-
Bringmann, G.1
Rübenacker, M.2
Jansen, J.R.3
Scheutzow, D.4
-
6
-
-
0027950656
-
Activity of extracts and naphthylisoquinoline alkaloids from Triphyophyllum peltatum, Ancistrocladus abbreviatus and A. barteri against Plasmodium falciparum in vitro
-
Francois G., Bringmann G., Phillipson J.D., Aké Assi L., Dochez C., Rübenacker M., Schneider C., Wéry M., Warhust D.C., Kirby G.C. Activity of extracts and naphthylisoquinoline alkaloids from Triphyophyllum peltatum, Ancistrocladus abbreviatus and A. barteri against Plasmodium falciparum in vitro. Phytochemistry 1994, 35:1461-1464.
-
(1994)
Phytochemistry
, vol.35
, pp. 1461-1464
-
-
Francois, G.1
Bringmann, G.2
Phillipson, J.D.3
Aké Assi, L.4
Dochez, C.5
Rübenacker, M.6
Schneider, C.7
Wéry, M.8
Warhust, D.C.9
Kirby, G.C.10
-
7
-
-
0040299136
-
Naphthylisoquinoline alkaloids against malaria: evaluation of the curative potentials of dioncophylline C and dioncopeltine A against Plasmodium berghei in vivo
-
Francois G., Timperman G., Eling W., Aké Assi L., Holenz J., Bringmann G. Naphthylisoquinoline alkaloids against malaria: evaluation of the curative potentials of dioncophylline C and dioncopeltine A against Plasmodium berghei in vivo. Antimicrob. Agents Chemother. 1997, 41:2533-2539.
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 2533-2539
-
-
Francois, G.1
Timperman, G.2
Eling, W.3
Aké Assi, L.4
Holenz, J.5
Bringmann, G.6
-
8
-
-
77952919960
-
-
Council of Europe, Strasbourg, C. Europe (Ed.), European Directorate for Quality of Medicines
-
European Directorate for Quality of Medicines European Pharmacopoeia 2008, Council of Europe, Strasbourg. C. Europe (Ed.).
-
(2008)
European Pharmacopoeia
-
-
-
9
-
-
0003806519
-
-
Springer Medizin Verlag, Heidelberg
-
Blaschek W., Ebel S., Hackenthal E., Holzgrabe U., Keller K., Reichling J., Schulz V. Hagers Handbuch der Pharmazeutischen Praxis 2009, Springer Medizin Verlag, Heidelberg.
-
(2009)
Hagers Handbuch der Pharmazeutischen Praxis
-
-
Blaschek, W.1
Ebel, S.2
Hackenthal, E.3
Holzgrabe, U.4
Keller, K.5
Reichling, J.6
Schulz, V.7
-
10
-
-
78751701373
-
-
Purification of 1-ethyl-6,7-methylenedioxy-4(1H)-oxocinnoline-3-carboxylic acid, a urinary tract antibacterial, DD 1983-249852 ed., Deutschland, 1987.
-
G. Kammann, G. Dietz, H. Schmidt, J. Franke, R. Scheffler, H. Toenjes, Purification of 1-ethyl-6,7-methylenedioxy-4(1H)-oxocinnoline-3-carboxylic acid, a urinary tract antibacterial, DD 1983-249852 ed., Deutschland, 1987.
-
-
-
Kammann, G.1
Dietz, G.2
Schmidt, H.3
Franke, J.4
Scheffler, R.5
Toenjes, H.6
-
11
-
-
33746952940
-
High-performance liquid chromatographic method for simple and rapid determination of linezolid in human plasma
-
Boak L.M., Li J., Nation R.L., Rayner C.R. High-performance liquid chromatographic method for simple and rapid determination of linezolid in human plasma. Biomed. Chromatogr. 2006, 20:782-786.
-
(2006)
Biomed. Chromatogr.
, vol.20
, pp. 782-786
-
-
Boak, L.M.1
Li, J.2
Nation, R.L.3
Rayner, C.R.4
-
12
-
-
0034781264
-
Determination of linezolid in human serum and urine by high-performance liquid chromatography
-
Borner K., Borner E., Lode H. Determination of linezolid in human serum and urine by high-performance liquid chromatography. Int. J. Antimicrob. Agents 2001, 18:253-258.
-
(2001)
Int. J. Antimicrob. Agents
, vol.18
, pp. 253-258
-
-
Borner, K.1
Borner, E.2
Lode, H.3
-
13
-
-
0037023371
-
Multiresidue determination of (fluoro)quinolone antibiotics in swine kidney using liquid chromatography-tandem mass spectrometry
-
van Vyncht G., Jànosi A., Bordin G., Toussaint B., Maghuin-Rogister G., De Pauw E., Rodriguez A.R. Multiresidue determination of (fluoro)quinolone antibiotics in swine kidney using liquid chromatography-tandem mass spectrometry. J. Chromatogr. A 2002, 952:121-129.
-
(2002)
J. Chromatogr. A
, vol.952
, pp. 121-129
-
-
van Vyncht, G.1
Jànosi, A.2
Bordin, G.3
Toussaint, B.4
Maghuin-Rogister, G.5
De Pauw, E.6
Rodriguez, A.R.7
-
14
-
-
0022450259
-
Isolation and structural elucidation of urinary metabolites of ciprofloxacin
-
Gau W., Kurz J., Petersen U., Ploschke H.J., Wuensche C. Isolation and structural elucidation of urinary metabolites of ciprofloxacin. Arzneim. Forsch. 1986, 36:1545-1549.
-
(1986)
Arzneim. Forsch.
, vol.36
, pp. 1545-1549
-
-
Gau, W.1
Kurz, J.2
Petersen, U.3
Ploschke, H.J.4
Wuensche, C.5
-
15
-
-
0030820527
-
Study of 4-quinolone antibiotics in biological samples by short-column liquid chromatography coupled with electrospray ionization tandem mass spectrometry
-
Volmer D.A., Mansoori B., Locke S.J. Study of 4-quinolone antibiotics in biological samples by short-column liquid chromatography coupled with electrospray ionization tandem mass spectrometry. Anal. Chem. 1997, 69:4143-4155.
-
(1997)
Anal. Chem.
, vol.69
, pp. 4143-4155
-
-
Volmer, D.A.1
Mansoori, B.2
Locke, S.J.3
-
16
-
-
0029550446
-
HPLC analysis of ciprofloxacin and ciprofloxacin metabolites in body fluids
-
Krol G.J., Beck G.W., Benham T. HPLC analysis of ciprofloxacin and ciprofloxacin metabolites in body fluids. J. Pharm. Biomed. Anal. 1995, 14:181-190.
-
(1995)
J. Pharm. Biomed. Anal.
, vol.14
, pp. 181-190
-
-
Krol, G.J.1
Beck, G.W.2
Benham, T.3
-
17
-
-
0035189149
-
Pharmacokinetics and residues of ciprofloxacin and its metabolites in broiler chickens
-
Anadón A., Martinez-Larranga M.R., Iturbe J., Martinez M.A., Diaz M.J., Frejo M.T., Martinez M. Pharmacokinetics and residues of ciprofloxacin and its metabolites in broiler chickens. Res. Vet. Sci. 2001, 71:101-109.
-
(2001)
Res. Vet. Sci.
, vol.71
, pp. 101-109
-
-
Anadón, A.1
Martinez-Larranga, M.R.2
Iturbe, J.3
Martinez, M.A.4
Diaz, M.J.5
Frejo, M.T.6
Martinez, M.7
-
18
-
-
45149089342
-
Characterization of intermediate compounds formed upon photoinduced degradation of quinolones by high-performance liquid chromatography/high-resolution multiple-stage mass spectrometry
-
Calza P., Medana C., Carbone F., Giancotti V., Baiocchi C. Characterization of intermediate compounds formed upon photoinduced degradation of quinolones by high-performance liquid chromatography/high-resolution multiple-stage mass spectrometry. Rapid Commun. Mass Spectrom. 2008, 22:1533-1552.
-
(2008)
Rapid Commun. Mass Spectrom.
, vol.22
, pp. 1533-1552
-
-
Calza, P.1
Medana, C.2
Carbone, F.3
Giancotti, V.4
Baiocchi, C.5
-
19
-
-
0032957077
-
Degradation of ciprofloxacin by basidiomycetes and identification of metabolites generated by the brown rot fungus Gloeophyllum striatum
-
Wetzstein H.G., Stadler M., Tichy H.V., Dalhoff A., Karl W. Degradation of ciprofloxacin by basidiomycetes and identification of metabolites generated by the brown rot fungus Gloeophyllum striatum. Appl. Environ. Microbiol. 1999, 65:1556-1563.
-
(1999)
Appl. Environ. Microbiol.
, vol.65
, pp. 1556-1563
-
-
Wetzstein, H.G.1
Stadler, M.2
Tichy, H.V.3
Dalhoff, A.4
Karl, W.5
-
21
-
-
4243609259
-
Chemie pharmakokinetik und pharmakodynamik von linezolid
-
Socio-medico Verlag, Wessobrunn, C. von Eiff (Ed.)
-
Sörgel F., Bulitta J., Kinzig-Schippers M. Chemie pharmakokinetik und pharmakodynamik von linezolid. Oxazolidinone-Aktuelle Erkenntnisse zu einer neuen Klasse von Antibiotika 2001, 59-96. Socio-medico Verlag, Wessobrunn. C. von Eiff (Ed.).
-
(2001)
Oxazolidinone-Aktuelle Erkenntnisse zu einer neuen Klasse von Antibiotika
, pp. 59-96
-
-
Sörgel, F.1
Bulitta, J.2
Kinzig-Schippers, M.3
-
22
-
-
0035015349
-
Determination of linezolid in human plasma by LC-MS-MS
-
Phillips O.A., Abdel-Hamid M., Al-Hassawi N.A. Determination of linezolid in human plasma by LC-MS-MS. Analyst 2001, 126:609-614.
-
(2001)
Analyst
, vol.126
, pp. 609-614
-
-
Phillips, O.A.1
Abdel-Hamid, M.2
Al-Hassawi, N.A.3
-
23
-
-
1842503152
-
Liquid chromatography-tandem mass spectrometry for the determination of a new oxazolidinone antibiotic DA-7867 in human plasma
-
Ji H.Y., Lee H.W., Chang S.G., Lee J.J., Rhee J.K., Kim W.B., Lee H.S. Liquid chromatography-tandem mass spectrometry for the determination of a new oxazolidinone antibiotic DA-7867 in human plasma. Biomed. Chromatogr. 2004, 18:86-89.
-
(2004)
Biomed. Chromatogr.
, vol.18
, pp. 86-89
-
-
Ji, H.Y.1
Lee, H.W.2
Chang, S.G.3
Lee, J.J.4
Rhee, J.K.5
Kim, W.B.6
Lee, H.S.7
-
24
-
-
59049090171
-
Liquid chromatography-tandem mass spectrometry for the determination of jaceosidin in rat plasma
-
Song W.Y., Kim N.J., Kim S.Y., Lee H.S. Liquid chromatography-tandem mass spectrometry for the determination of jaceosidin in rat plasma. J. Pharm. Biomed. Anal. 2009, 49:381-386.
-
(2009)
J. Pharm. Biomed. Anal.
, vol.49
, pp. 381-386
-
-
Song, W.Y.1
Kim, N.J.2
Kim, S.Y.3
Lee, H.S.4
-
25
-
-
34547671034
-
Determination of a selective Na+/H+ exchanger inhibitor, 4-cyano(benzo[b]thiophene-2-carbonyl)guanidine (KR-33028) in rat plasma by liquid chromatography-tandem mass spectrometry
-
Kim Y.H., Ji H.Y., Lee S., Yi K.Y., Kim Y.S., Lee K.H., Lee H.S. Determination of a selective Na+/H+ exchanger inhibitor, 4-cyano(benzo[b]thiophene-2-carbonyl)guanidine (KR-33028) in rat plasma by liquid chromatography-tandem mass spectrometry. Biomed. Chromatogr. 2007, 21:810-815.
-
(2007)
Biomed. Chromatogr.
, vol.21
, pp. 810-815
-
-
Kim, Y.H.1
Ji, H.Y.2
Lee, S.3
Yi, K.Y.4
Kim, Y.S.5
Lee, K.H.6
Lee, H.S.7
-
26
-
-
0034932457
-
Pharmakokinetics, metabolism, and excretion of linezolid following an oral dose of [14C]linezolid to healthy human subjects
-
Slatter J.G., Stalker D.J., Feenstra K.L., Welshman I.R., Bruss J.B., Sams J.P., Johnson M.G., Sanders P.E., Hauer M.J., Fagerness P.E., Stryd R.P., Peng G.W., Shobe E.M. Pharmakokinetics, metabolism, and excretion of linezolid following an oral dose of [14C]linezolid to healthy human subjects. Drug Metab. Dispos. 2001, 29:1136-1145.
-
(2001)
Drug Metab. Dispos.
, vol.29
, pp. 1136-1145
-
-
Slatter, J.G.1
Stalker, D.J.2
Feenstra, K.L.3
Welshman, I.R.4
Bruss, J.B.5
Sams, J.P.6
Johnson, M.G.7
Sanders, P.E.8
Hauer, M.J.9
Fagerness, P.E.10
Stryd, R.P.11
Peng, G.W.12
Shobe, E.M.13
-
27
-
-
0027104930
-
Enzymatic biotransformation of naphthylisoquinoline alkaloids: first hints at the metabolism of dioncophylline A
-
Bringmann G, Gramatzki S., God R., Proksch P. Enzymatic biotransformation of naphthylisoquinoline alkaloids: first hints at the metabolism of dioncophylline A. Planta Med. 1992, 58:577-578.
-
(1992)
Planta Med.
, vol.58
, pp. 577-578
-
-
Bringmann, G.1
Gramatzki, S.2
God, R.3
Proksch, P.4
-
28
-
-
33748699324
-
Biotransformation and pharmacokinetics of the antiplasmodial naphthylisoquinoline alkaloid dioncophylline A
-
Sieber M., Dekant W., Faber J.H., Bringmann G. Biotransformation and pharmacokinetics of the antiplasmodial naphthylisoquinoline alkaloid dioncophylline A. Xenobiotica 2006, 36:750-762.
-
(2006)
Xenobiotica
, vol.36
, pp. 750-762
-
-
Sieber, M.1
Dekant, W.2
Faber, J.H.3
Bringmann, G.4
-
29
-
-
0000511961
-
Atrop-diastereomer separation by racemate resolution techniques: N-methyl-dioncophylline A and its 7-epimer from Ancistrocladus abbreviatus
-
Bringmann G., Lisch D., Reuscher H., Aké Assi L., Günther K. Atrop-diastereomer separation by racemate resolution techniques: N-methyl-dioncophylline A and its 7-epimer from Ancistrocladus abbreviatus. Phytochemistry 1991, 30:1307-1310.
-
(1991)
Phytochemistry
, vol.30
, pp. 1307-1310
-
-
Bringmann, G.1
Lisch, D.2
Reuscher, H.3
Aké Assi, L.4
Günther, K.5
-
30
-
-
0037310714
-
Habropetaline A, an antimalarial naphthylisoquinoline alkaloid from Triphyophyllum peltatum
-
Bringmann G., Messer K., Schwöbel B., Brun R., Aké Assi L. Habropetaline A, an antimalarial naphthylisoquinoline alkaloid from Triphyophyllum peltatum. Phytochemistry 2003, 62:345-349.
-
(2003)
Phytochemistry
, vol.62
, pp. 345-349
-
-
Bringmann, G.1
Messer, K.2
Schwöbel, B.3
Brun, R.4
Aké Assi, L.5
-
31
-
-
0037272197
-
Strategies and molecular probes to investigate the role of cytochrome P450 in drug metabolism
-
Donato M.T, Castell J.V. Strategies and molecular probes to investigate the role of cytochrome P450 in drug metabolism. Clin. Pharmacokinet. 2003, 42:153-178.
-
(2003)
Clin. Pharmacokinet.
, vol.42
, pp. 153-178
-
-
Donato, M.T.1
Castell, J.V.2
-
32
-
-
0034488711
-
In vitro methoden zur untersuchung des phase-I metabolismus
-
Härtter S. In vitro methoden zur untersuchung des phase-I metabolismus. Pharm. Unserer Zeit 2000, 29:365-371.
-
(2000)
Pharm. Unserer Zeit
, vol.29
, pp. 365-371
-
-
Härtter, S.1
|