Mutant human β4 subunit identified in amyotrophic lateral sclerosis patients impairs nicotinic receptor function

Pflugers Archiv European Journal of Physiology

Volumn 461, Issue 2, 2011, Pages 225-233

  Moriconi, Claudia ^a   Di Angelantonio, Silvia ^a   Piccioni, Alessio ^a   Trettel, Flavia ^a   Sabatelli, Mario ^b   Grassi, Francesca ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b CATHOLIC UNIVERSITY   (Italy)

Author keywords

Amyotrophic lateral sclerosis; Desensitization; Nicotinic receptor; Receptor expression; Whole cell recording

Indexed keywords

COMPLEMENTARY DNA; NICOTINE; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA4; NICOTINIC RECEPTOR ALPHA4BETA4; NICOTINIC RECEPTOR BETA4 SUBUNIT; UNCLASSIFIED DRUG;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ARTICLE; CELL CULTURE; CIGARETTE SMOKING; CONTROLLED STUDY; DESENSITIZATION; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; GENE EXPRESSION; GENE MUTATION; GENETIC TRANSFECTION; INTRACELLULAR RECORDING; INTRACELLULAR SIGNALING; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; WILD TYPE;

ACETYLCHOLINE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; CELL LINE; HUMANS; PATCH-CLAMP TECHNIQUES; RATS; RECEPTORS, NICOTINIC;

EID: 78751649910     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-010-0905-2     Document Type: Article

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