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Volumn 461, Issue 1, 2011, Pages 153-164

Uncoupling protein 3 expression levels influence insulin sensitivity, fatty acid oxidation, and related signaling pathways

Author keywords

Akt PKB; AMPK; GLUT4; Insulin; Uncoupling protein 3

Indexed keywords

ENZYME; GLUCOSE; GLUCOSE TRANSPORTER 4; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN KINASE B; PROTEIN PEPCK; SERINE; THREONINE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 3;

EID: 78751646635     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-010-0892-3     Document Type: Article
Times cited : (41)

References (39)
  • 1
    • 0031560941 scopus 로고    scopus 로고
    • UCP3: An uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue
    • DOI 10.1006/bbrc.1997.6740
    • A Vidal-Puig G Solanes D Grujic JS Flier BB Lowell 1997 UCP-3, an uncoupling protein homolog expressed preferentially and abundantly in skeletal muscle and brown adipose tissue Biochem Biophys Res Commun 235 79 82 1:CAS:528:DyaK2sXjvFSktb4%3D 10.1006/bbrc.1997.6740 9196039 (Pubitemid 27302688)
    • (1997) Biochemical and Biophysical Research Communications , vol.235 , Issue.1 , pp. 79-82
    • Vidal-Puig, A.1    Solanes, G.2    Grujic, D.3    Flier, J.S.4    Lowell, B.B.5
  • 2
    • 0027731309 scopus 로고
    • Development of obesity in transgenic mice after genetic ablation of brown adipose tissue
    • DOI 10.1038/366740a0
    • BB Lowell VS Susulic A Hamann JA Lawitts J Himms-Hagen BB Boyer LP Kozak JS Flier 1993 Development of obesity in transgenic mice after genetic ablation of brown adipose tissue Nature 366 740 742 1:CAS:528:DyaK2cXhtVCjsLs%3D 10.1038/366740a0 8264795 (Pubitemid 24038513)
    • (1993) Nature , vol.366 , Issue.6457 , pp. 740-742
    • Lowell, B.B.1    S-Susulic, V.2    Hamann, A.3    Lawitts, J.A.4    Himms-Hagen, J.5    Boyer, B.B.6    Kozak, L.P.7    Flier, J.S.8
  • 3
    • 14844307015 scopus 로고    scopus 로고
    • Thyroid-hormone effects on putative biochemical pathways involved in UCP3 activation in rat skeletal muscle mitochondria
    • DOI 10.1016/j.febslet.2005.02.022
    • E Silvestri M Moreno A Lombardi M Ragni P de Lange SE Alexson A Lanni F Goglia 2005 Thyroid hormone effects on putative biochemical pathways involved in UCP3 activation in rat skeletal muscle mitochondria FEBS Lett 579 1639 1645 1:CAS:528:DC%2BD2MXitFChsrs%3D 10.1016/j.febslet.2005.02.022 15757654 (Pubitemid 40341536)
    • (2005) FEBS Letters , vol.579 , Issue.7 , pp. 1639-1645
    • Silvestri, E.1    Moreno, M.2    Lombardi, A.3    Ragni, M.4    De Lange, P.5    Alexson, S.E.H.6    Lanni, A.7    Goglia, F.8
  • 4
    • 0030869755 scopus 로고    scopus 로고
    • Uncoupling protein-3 is a mediator of thermogenesis regulated by thyroid hormone, β3-adrenergic agonists, and leptin
    • DOI 10.1074/jbc.272.39.24129
    • DW Gong Y He M Karas M Reitman 1997 Uncoupling protein-3 is a mediator of thermogenesis regulated by thyroid hormone, beta3-adrenergic agonists, and leptin J Biol Chem 272 24129 24132 1:CAS:528:DyaK2sXmsFanur0%3D 10.1074/jbc.272.39.24129 9305858 (Pubitemid 27418606)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.39 , pp. 24129-24132
    • Gong, D.-W.1    He, Y.2    Karas, M.3    Reitman, M.4
  • 5
    • 0033040742 scopus 로고    scopus 로고
    • Expression of uncoupling protein-3 and mitochondrial activity in the transition from hypothyroid to hyperthyroid state in rat skeletal muscle
    • DOI 10.1016/S0014-5793(99)00061-7, PII S0014579399000617
    • A Lanni L Beneduce A Lombardi M Moreno O Boss P Muzzin JP Giacobino F Goglia 1999 Expression of uncoupling protein-3 and mitochondrial activity in the transition from hypothyroid to hyperthyroid state in rat skeletal muscle FEBS Lett 444 250 254 1:CAS:528:DyaK1MXhtFaqsbY%3D 10.1016/S0014-5793(99)00061-7 10050769 (Pubitemid 29092812)
    • (1999) FEBS Letters , vol.444 , Issue.2-3 , pp. 250-254
    • Lanni, A.1    Beneduce, L.2    Lombardi, A.3    Moreno, M.4    Boss, O.5    Muzzin, P.6    Giacobino, J.P.7    Goglia, F.8
  • 6
    • 0034925407 scopus 로고    scopus 로고
    • Uncoupling protein-3 is a molecular determinant for the regulation of resting metabolic rate by thyroid hormone
    • DOI 10.1210/en.142.8.3414
    • P De Lange A Lanni L Beneduce M Moreno A Lombardi E Silvestri F Goglia 2001 Uncoupling protein-3 is a molecular determinant for the regulation of resting metabolic rate by thyroid hormone Endocrinology 142 3414 3420 10.1210/en.142.8.3414 11459785 (Pubitemid 32681747)
    • (2001) Endocrinology , vol.142 , Issue.8 , pp. 3414-3420
    • De Lange, P.1    Lanni, A.2    Beneduce, L.3    Moreno, M.4    Lombardi, A.5    Silvestri, E.6    Goglia, F.7
  • 7
    • 0031748933 scopus 로고    scopus 로고
    • Chronic central leptin infusion enhances insulin-stimulated glucose metabolism and favors the expression of uncoupling proteins
    • DOI 10.2337/diabetes.47.7.1014
    • I Cusin KE Zakrzewska O Boss P Muzzin JP Giacobino D Ricquier B Jeanrenaud F Rohner-Jeanrenaud 1998 Chronic central leptin infusion enhances insulin-stimulated glucose metabolism and favors the expression of uncoupling proteins Diabetes 47 1014 1019 1:CAS:528:DyaK1cXkt1ajt78%3D 10.2337/diabetes.47. 7.1014 9648822 (Pubitemid 28294541)
    • (1998) Diabetes , vol.47 , Issue.7 , pp. 1014-1019
    • Cusin, I.1    Zakrzewska, K.E.2    Boss, O.3    Muzzin, P.4    Giacobino, J.-P.5    Ricquier, D.6    Jeanrenaud, B.7    Rohner-Jeanrenaud, F.8
  • 8
    • 0035371770 scopus 로고    scopus 로고
    • Cold-induced changes in the energy coupling and the UCP3 level in rodent skeletal muscles
    • DOI 10.1016/S0005-2728(01)00168-2, PII S0005272801001682
    • RA Simonyan M Jimenez RB Ceddia JP Giacobino P Muzzin VP Skulachev 2001 Cold-induced changes in the energy coupling and the UCP3 level in rodent skeletal muscles Biochim Biophys Acta 1505 271 279 1:CAS:528: DC%2BD3MXjtFGitbo%3D 10.1016/S0005-2728(01)00168-2 11334791 (Pubitemid 32378777)
    • (2001) Biochimica et Biophysica Acta - Bioenergetics , vol.1505 , Issue.2-3 , pp. 271-279
    • Simonyan, R.A.1    Jimenez, M.2    Ceddia, R.B.3    Giacobino, J.-P.4    Muzzin, P.5    Skulachev, V.P.6
  • 10
    • 1442339215 scopus 로고    scopus 로고
    • Combined cDNA/RT-PCR analysis of gene expression profile in rat gastrocnemius muscle: Relation to its adaptative function in energy metabolism during fasting
    • 14656997
    • P De Lange M Ragni E Silvestri M Moreno L Schiavo A Lombardi P Farina A Feola F Goglia A Lanni 2004 Combined cDNA/RT-PCR analysis of gene expression profile in rat gastrocnemius muscle: relation to its adaptative function in energy metabolism during fasting FASEB J 18 350 352 14656997
    • (2004) FASEB J , vol.18 , pp. 350-352
    • De Lange, P.1    Ragni, M.2    Silvestri, E.3    Moreno, M.4    Schiavo, L.5    Lombardi, A.6    Farina, P.7    Feola, A.8    Goglia, F.9    Lanni, A.10
  • 11
    • 33845655927 scopus 로고    scopus 로고
    • Sequential changes in the signal transduction responses of skeletal muscle following food deprivation
    • DOI 10.1096/fj.06-6025fje
    • P De Lange P Farina M Moreno M Ragni A Lombardi E Silvestri L Burrone A Lanni F Goglia 2006 Sequential changes in the signal transduction responses of skeletal muscle following food deprivation FASEB J 20 2579 2581 10.1096/fj.06-6025fje 17065218 (Pubitemid 44953786)
    • (2006) FASEB Journal , vol.20 , Issue.14
    • De Lange, P.1    Farina, P.2    Moreno, M.3    Ragni, M.4    Lombardi, A.5    Silvestri, E.6    Burrone, L.7    Lanni, A.8    Goglia, F.9
  • 12
    • 0032742372 scopus 로고    scopus 로고
    • UCP2 and UCP3 rise in starved rat skeletal muscle but mitochondrial proton conductance is unchanged
    • 1:CAS:528:DyaK1MXnslGktL4%3D 10.1016/S0014-5793(99)01540-9 10622707
    • S Cadenas JA Buckingham S Samec J Seydoux N Din AG Dulloo MD Brand 1999 UCP2 and UCP3 rise in starved rat skeletal muscle but mitochondrial proton conductance is unchanged FEBS Lett 462 257 260 1:CAS:528:DyaK1MXnslGktL4%3D 10.1016/S0014-5793(99)01540-9 10622707
    • (1999) FEBS Lett , vol.462 , pp. 257-260
    • Cadenas, S.1    Buckingham, J.A.2    Samec, S.3    Seydoux, J.4    Din, N.5    Dulloo, A.G.6    Brand, M.D.7
  • 14
    • 0042415622 scopus 로고    scopus 로고
    • A function for novel uncoupling proteins: Antioxidant defense of mitochondrial matrix by translocating fatty acid peroxides from the inner to the outer membrane leaflet
    • DOI 10.1096/fj.03-0159hyp
    • F Goglia VP Skulachev 2003 A function for novel uncoupling proteins: antioxidant defense of mitochondrial matrix by translocating fatty acid peroxides from the inner to the outer membrane leaflet FASEB J 17 1585 1591 1:CAS:528:DC%2BD3sXntlSrs70%3D 10.1096/fj.03-0159hyp 12958165 (Pubitemid 37100060)
    • (2003) FASEB Journal , vol.17 , Issue.12 , pp. 1585-1591
    • Goglia, F.1    Skulachev, V.P.2
  • 15
    • 77952759283 scopus 로고    scopus 로고
    • Uncoupling protein-3 (UCP3) translocates lipid hydroperoxide and mediates lipid hydroperoxide-dependent mitochondrial uncoupling
    • 1:CAS:528:DC%2BC3cXmtlygsL0%3D 10.1074/jbc.M110.102699 20363757
    • A Lombardi RA Busiello L Napolitano F Cioffi M Moreno P de Lange E Silvestri A Lanni F Goglia 2010 Uncoupling protein-3 (UCP3) translocates lipid hydroperoxide and mediates lipid hydroperoxide-dependent mitochondrial uncoupling J Biol Chem 285 16599 16605 1:CAS:528:DC%2BC3cXmtlygsL0%3D 10.1074/jbc.M110.102699 20363757
    • (2010) J Biol Chem , vol.285 , pp. 16599-16605
    • Lombardi, A.1    Busiello, R.A.2    Napolitano, L.3    Cioffi, F.4    Moreno, M.5    De Lange, P.6    Silvestri, E.7    Lanni, A.8    Goglia, F.9
  • 16
    • 54449089267 scopus 로고    scopus 로고
    • Essential role for uncoupling protein-3 in mitochondrial adaptation to fasting but not in fatty acid oxidation or fatty acid anion export
    • EL Seifert V Bezaire C Estay ME Harper 2008 Essential role for uncoupling protein-3 in mitochondrial adaptation to fasting but not in fatty acid oxidation or fatty acid anion export J Biol Chem 283 25134 25131
    • (2008) J Biol Chem , vol.283 , pp. 25134-25131
    • Seifert, E.L.1    Bezaire, V.2    Estay, C.3    Harper, M.E.4
  • 17
    • 33846813359 scopus 로고    scopus 로고
    • Uncoupling protein-3: Clues in an ongoing mitochondrial mystery
    • DOI 10.1096/fj.06-6966rev
    • V Bezaire EL Seifert ME Harper 2007 Uncoupling protein-3: clues in an ongoing mitochondrial mystery FASEB J 21 312 324 1:CAS:528:DC%2BD2sXhslGqsb8%3D 10.1096/fj.06-6966rev 17202247 (Pubitemid 46213479)
    • (2007) FASEB Journal , vol.21 , Issue.2 , pp. 312-324
    • Bezaire, V.1    Seifert, E.L.2    Harper, M.-E.3
  • 18
    • 0031832185 scopus 로고    scopus 로고
    • Role of UCP homologues in skeletal muscles and brown adipose tissue: Mediators of thermogenesis or regulators of lipids as fuel substrate?
    • 1:CAS:528:DyaK1cXjsVymsbs%3D 9619450
    • S Samec J Seydoux AG Dulloo 1998 Role of UCP homologues in skeletal muscles and brown adipose tissue: mediators of thermogenesis or regulators of lipids as fuel substrate? FASEB J 12 715 724 1:CAS:528:DyaK1cXjsVymsbs%3D 9619450
    • (1998) FASEB J , vol.12 , pp. 715-724
    • Samec, S.1    Seydoux, J.2    Dulloo, A.G.3
  • 19
    • 0005989232 scopus 로고    scopus 로고
    • Downregulation of skeletal muscle UCP-3 gene expression during refeeding is prevented by cold exposure
    • DOI 10.1007/s004240050998
    • S Samec J Seydoux AG Dulloo 2000 Downregulation of skeletal muscle UCP-3 gene expression during refeeding is prevented by cold exposure Pflugers Arch 439 723 729 1:CAS:528:DC%2BD3cXis1Glur4%3D 10.1007/s004240050998 10784346 (Pubitemid 30191146)
    • (2000) Pflugers Archiv European Journal of Physiology , vol.439 , Issue.6 , pp. 723-729
    • Samec, S.1    Seydoux, J.2    Dulloo, A.G.3
  • 20
    • 35948975126 scopus 로고    scopus 로고
    • Fuel economy in food-deprived skeletal muscle: Signaling pathways and regulatory mechanisms
    • DOI 10.1096/fj.07-8527rev
    • P De Lange M Moreno E Silvestri A Lombardi F Goglia A Lanni 2007 Fuel economy in food-deprived skeletal muscle: signalling pathways and regulatory mechanisms [review] FASEB J 21 3431 3441 10.1096/fj.07-8527rev 17595346 (Pubitemid 350075134)
    • (2007) FASEB Journal , vol.21 , Issue.13 , pp. 3431-3441
    • De Lange, P.1    Moreno, M.2    Silvestri, E.3    Lombardi, A.4    Goglia, F.5    Lanni, A.6
  • 23
    • 0035918162 scopus 로고    scopus 로고
    • Uncoupling protein 3 (UCP3) stimulates glucose uptake in muscle cells through a phosphoinositide 3-kinase-dependent mechanism
    • 1:CAS:528:DC%2BD3MXjtFyntrg%3D 10.1074/jbc.M011708200 11278970
    • C Huppertz BM Fischer YB Kim K Kotani A Vidal-Puig LJ Slieker KW Sloop BB Lowell BB Kahn 2001 Uncoupling protein 3 (UCP3) stimulates glucose uptake in muscle cells through a phosphoinositide 3-kinase-dependent mechanism J Biol Chem 276 12520 12529 1:CAS:528:DC%2BD3MXjtFyntrg%3D 10.1074/jbc.M011708200 11278970
    • (2001) J Biol Chem , vol.276 , pp. 12520-12529
    • Huppertz, C.1    Fischer, B.M.2    Kim, Y.B.3    Kotani, K.4    Vidal-Puig, A.5    Slieker, L.J.6    Sloop, K.W.7    Lowell, B.B.8    Kahn, B.B.9
  • 24
    • 33744945764 scopus 로고    scopus 로고
    • Effects of the presence, absence, and overexpression of uncoupling protein-3 on adiposity and fuel metabolism in congenic mice
    • DOI 10.1152/ajpendo.00401.2005
    • SR Costford SN Chaudhry M Salkhordeh ME Harper 2006 Effects of the presence, absence, and overexpression of uncoupling protein-3 on adiposity and fuel metabolism in congenic mice Am J Physiol Endocrinol Metab 290 E1304 E1312 1:CAS:528:DC%2BD28XlvVeisrg%3D 10.1152/ajpendo.00401.2005 16434555 (Pubitemid 43847916)
    • (2006) American Journal of Physiology - Endocrinology and Metabolism , vol.290 , Issue.6
    • Costford, S.R.1    Chaudhry, S.N.2    Salkhordeh, M.3    Harper, M.-E.4
  • 25
    • 57049114918 scopus 로고    scopus 로고
    • Long-term high-fat feeding induces greater fat storage in mice lacking UCP3
    • 1:CAS:528:DC%2BD1cXhsVWkurbL 10.1152/ajpendo.00779.2007 18713955
    • SR Costford SN Chaudry SA Crawford M Salkhordeh ME Harper 2008 Long-term high-fat feeding induces greater fat storage in mice lacking UCP3 Am J Physiol Endocrinol Metab 295 E1018 E1021 1:CAS:528:DC%2BD1cXhsVWkurbL 10.1152/ajpendo.00779.2007 18713955
    • (2008) Am J Physiol Endocrinol Metab , vol.295
    • Costford, S.R.1    Chaudry, S.N.2    Crawford, S.A.3    Salkhordeh, M.4    Harper, M.E.5
  • 26
    • 0035654002 scopus 로고    scopus 로고
    • Uncoupling protein 3 content is decreased in skeletal muscle of patients with type 2 diabetes
    • 1:CAS:528:DC%2BD3MXovVOhs7k%3D 10.2337/diabetes.50.12.2870 11723073
    • P Schrauwen MKC Hesselink EE Blaak LB Borghouts G Schaart WHM Saris HA Keizer 2001 Uncoupling protein 3 content is decreased in skeletal muscle of patients with type 2 diabetes Diabetes 50 2870 2873 1:CAS:528: DC%2BD3MXovVOhs7k%3D 10.2337/diabetes.50.12.2870 11723073
    • (2001) Diabetes , vol.50 , pp. 2870-2873
    • Schrauwen, P.1    Hesselink, M.K.C.2    Blaak, E.E.3    Borghouts, L.B.4    Schaart, G.5    Saris, W.H.M.6    Keizer, H.A.7
  • 27
    • 66749094133 scopus 로고    scopus 로고
    • Plasma acylcarnitine profiles suggest incomplete long-chain fatty acid (beta) oxidation and altered tricarboxylic acid cycle activity in type 2 diabetic African-American women
    • 1:CAS:528:DC%2BD1MXhtlWrtrfN 10.3945/jn.108.103754 19369366
    • SH Adams CL Hoppel KH Lok L Zhao SW Wong PE Minkler DH Hwang JW Newman WT Garvey 2009 Plasma acylcarnitine profiles suggest incomplete long-chain fatty acid (beta) oxidation and altered tricarboxylic acid cycle activity in type 2 diabetic African-American women J Nutr 139 1073 1081 1:CAS:528: DC%2BD1MXhtlWrtrfN 10.3945/jn.108.103754 19369366
    • (2009) J Nutr , vol.139 , pp. 1073-1081
    • Adams, S.H.1    Hoppel, C.L.2    Lok, K.H.3    Zhao, L.4    Wong, S.W.5    Minkler, P.E.6    Hwang, D.H.7    Newman, J.W.8    Garvey, W.T.9
  • 28
    • 69449089547 scopus 로고    scopus 로고
    • The polymorphisms of UCP2 and UCP3 genes associated with fat metabolism, obesity and diabetes
    • 1:CAS:528:DC%2BD1MXht1WqsbbN 10.1111/j.1467-789X.2009.00569.x 19413708
    • J-J Jia X Zhang CR Ge M Jois 2009 The polymorphisms of UCP2 and UCP3 genes associated with fat metabolism, obesity and diabetes Obes Rev 10 519 526 1:CAS:528:DC%2BD1MXht1WqsbbN 10.1111/j.1467-789X.2009.00569.x 19413708
    • (2009) Obes Rev , vol.10 , pp. 519-526
    • Jia, J.-J.1    Zhang, X.2    Ge, C.R.3    Jois, M.4
  • 30
    • 34548486232 scopus 로고    scopus 로고
    • Resistance to high-fat-diet-induced obesity and sexual dimorphism in the metabolic responses of transgenic mice with moderate uncoupling protein 3 overexpression in glycolytic skeletal muscles
    • DOI 10.1007/s00125-007-0765-2
    • C Tiraby G Tavernier F Capel A Mairal F Crampes J Rami C Pujol LD Boutin 2007 Resistance to high-fat-diet-induced obesity and sexual dimorphism in the metabolic responses of transgenic mice with moderate uncoupling protein 3 overexpression in glycolytic skeletal muscles Diabetologia 50 2190 2199 1:CAS:528:DC%2BD2sXpvF2lsL4%3D 10.1007/s00125-007-0765-2 17676309 (Pubitemid 47373849)
    • (2007) Diabetologia , vol.50 , Issue.10 , pp. 2190-2199
    • Tiraby, C.1    Tavernier, G.2    Capel, F.3    Mairal, A.4    Crampes, F.5    Rami, J.6    Pujol, C.7    Boutin, J.A.8    Langin, D.9
  • 31
    • 0035204656 scopus 로고    scopus 로고
    • Aging skeletal muscle mitochondria in the rat: Decreased uncoupling protein-3 content
    • 1:CAS:528:DC%2BD3MXos1ahurk%3D
    • J Kerner PJ Turkaly PE Minkler CL Hoppel 2001 Aging skeletal muscle mitochondria in the rat: decreased uncoupling protein-3 content Am J Physiol Metab 281 E1054 E1062 1:CAS:528:DC%2BD3MXos1ahurk%3D
    • (2001) Am J Physiol Metab , vol.281
    • Kerner, J.1    Turkaly, P.J.2    Minkler, P.E.3    Hoppel, C.L.4
  • 32
    • 0023790275 scopus 로고
    • A novel type of short- and medium-chain acyl-CoA hydrolases in brown adipose tissue mitochondria
    • 1:CAS:528:DyaL1cXmt1Oiu7o%3D 2901416
    • SEH Alexson J Nedergaard 1988 A novel type of short- and medium-chain acyl-CoA hydrolases in brown adipose tissue mitochondria J Biol Chem 263 13564 13571 1:CAS:528:DyaL1cXmt1Oiu7o%3D 2901416
    • (1988) J Biol Chem , vol.263 , pp. 13564-13571
    • Alexson, S.E.H.1    Nedergaard, J.2
  • 34
    • 0026504451 scopus 로고
    • Effect of diabetes and fasting on GLUT-4 (muscle/fat) glucose transporter expression in insulin-sensitive tissues
    • 1:CAS:528:DyaK38XitFahsLs%3D 1554359
    • M Camps A Castello P Munoz M Monfar X Testar M Palacin A Zorzano 1992 Effect of diabetes and fasting on GLUT-4 (muscle/fat) glucose transporter expression in insulin-sensitive tissues Biochem J 282 765 772 1:CAS:528:DyaK38XitFahsLs%3D 1554359
    • (1992) Biochem J , vol.282 , pp. 765-772
    • Camps, M.1    Castello, A.2    Munoz, P.3    Monfar, M.4    Testar, X.5    Palacin, M.6    Zorzano, A.7
  • 35
    • 33644846005 scopus 로고    scopus 로고
    • Skeletal muscle lipid metabolism in exercise and insulin resistance
    • 1:CAS:528:DC%2BD28XhtlKntr4%3D 10.1152/physrev.00023.2004 16371598
    • B Kiens 2006 Skeletal muscle lipid metabolism in exercise and insulin resistance Physiol Rev 86 205 243 1:CAS:528:DC%2BD28XhtlKntr4%3D 10.1152/physrev.00023.2004 16371598
    • (2006) Physiol Rev , vol.86 , pp. 205-243
    • Kiens, B.1
  • 36
    • 57349181425 scopus 로고    scopus 로고
    • Rapid activation by 3, 5, 3'-L-triiodothyronine of AMPK/ACC and Akt/PKB signaling pathways: Relation to changes in fuel metabolism and myosin heavy chain protein content in rat gastrocnemius muscle in vivo
    • 10.1210/en.2008-0202 18703632
    • P De Lange R Senese F Cioffi M Moreno A Lombardi E Silvestri F Goglia A Lanni 2008 Rapid activation by 3, 5, 3'-L-triiodothyronine of AMPK/ACC and Akt/PKB signaling pathways: relation to changes in fuel metabolism and myosin heavy chain protein content in rat gastrocnemius muscle in vivo Endocrinology 149 6462 6470 10.1210/en.2008-0202 18703632
    • (2008) Endocrinology , vol.149 , pp. 6462-6470
    • De Lange, P.1    Senese, R.2    Cioffi, F.3    Moreno, M.4    Lombardi, A.5    Silvestri, E.6    Goglia, F.7    Lanni, A.8
  • 37
    • 33748954260 scopus 로고    scopus 로고
    • UCP2, UCP3, avUCP, what do they do when proton transport is not stimulated? Possible relevance to pyruvate and glutamine metabolism
    • F Criscuolo J Mozo C Hurtaud T Nubel F Bouillaud 2006 UCP2, UCP3, avUCP, what do they do when proton transport is not stimulated? Possible relevance to pyruvate and glutamine metabolism Biochim Biophys Acta 175 1284 1291
    • (2006) Biochim Biophys Acta , vol.175 , pp. 1284-1291
    • Criscuolo, F.1    Mozo, J.2    Hurtaud, C.3    Nubel, T.4    Bouillaud, F.5
  • 38
  • 39
    • 77949676576 scopus 로고    scopus 로고
    • Transcriptional profiling reveals divergent roles of PPAR alpha and PPAR beta/delta in regulation of gene expression in mouse liver
    • 20009009
    • LM Sanderson MV Boekschoten B Desvergne M Muller S Kersten 2009 Transcriptional profiling reveals divergent roles of PPAR alpha and PPAR beta/delta in regulation of gene expression in mouse liver Physiol Genomics 41 42 52 20009009
    • (2009) Physiol Genomics , vol.41 , pp. 42-52
    • Sanderson, L.M.1    Boekschoten, M.V.2    Desvergne, B.3    Muller, M.4    Kersten, S.5


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