Kinsenoside isolated from anoectochilus formosanus suppresses LPS-stimulated inflammatory reactions in macrophages and endotoxin shock in mice

Shock

Volumn 35, Issue 2, 2011, Pages 184-190

  Hsiao, Hung Bo ^a   Wu, Jin Bin ^b   Lin, Ho ^a   Lin, Wen Chuan ^c  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^b Graduate Institute of Pharmaceutical Chemistry   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Cytokine; inflammation; kinsenoside; LPS

Indexed keywords

DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; KINSENOSIDE; LIPOPOLYSACCHARIDE; MACROPHAGE MIGRATION INHIBITION FACTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; NITRIC OXIDE; PLANT EXTRACT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANOECTOCHILUS FORMOSANUS; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA PROTEIN COMPLEX; DRUG EFFECT; DRUG STRUCTURE; INFLAMMATION; MACROPHAGE; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; PERITONEUM LAVAGE; PROTEIN EXPRESSION; SEPTIC SHOCK; SURVIVAL RATE;

ANGIOSPERMS; ANIMALS; CYTOKINES; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; MACROPHAGES, PERITONEAL; MALE; MICE; MICE, INBRED ICR; MONOSACCHARIDES; NF-KAPPA B; SHOCK, SEPTIC;

EID: 78751632879     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e3181f0e7a3     Document Type: Article

References (25)

1. Fujiwara N, Kobayashi K: Macrophages in inflammation. Curr Drug Targets Inflamm Allergy 4:281-286, 2005.
2. Li Q, Verma IM: NF-.B regulation in the immune system. Nat Rev Immunol 2:725-734, 2002.
3. Du XM, Irino N, Furusho N, Hayashi J, Shoyama Y: Pharmacologically active compounds in the Anoectochilus and Goodyera species. J Nat Med 62:132-148, 2008.
4. Wu JB, Chuang HR, Yang LC, Lin WC: A Standardized aqueous extract of Anoectochilus formosanus ameliorated thioacetamide-induced liver fibrosis in mice: the role of Kupffer Cells. Biosci Biotechnol Biochem 74:781-787, 2010.
5. Wu JB, Lin WL, Hsieh CC, Ho HY, Tsay HS, Lin WC: The hepatoprotective activity of kinsenoside from Anoectochilus formosanus. Phytother Res 21: 58-61, 2007.
6. Chen CC, Wang JK, Lin SB: Antisense oligonucleotides targeting protein kinase C-alpha, -beta I, or -delta but not -eta inhibit lipopolysaccharide- induced nitric oxide synthase expression in RAW 264.7 macrophages: involvement of a nuclear factor kappa BYdependent mechanism. J Immunol 161:6206-6214, 1998.
7. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid gua-nidium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159, 1987.
8. Lee CJ, Tai YT, Lin YL, Chen RM: Molecular mechanisms of propofol-involved suppression of NO biosynthesis and inducible iNOS gene expression in LPS-stimulated macrophage-like RAW 264.7 cells. Shock 33:93-100, 2010.
9. Natherns AB, Bitar R, Marshall JC, Watson RW, Dackiw AP, Fan J, Hiscott J, Rotstein OD: Antioxidant increase lipopolysaccharide-stimulated TNF! increase in murine macrophages: role for altered TNF! mRNA stability. Shock 16:361-367, 2001.
10. Li S, Ni Z, Cong B, Gao W, Xu S, Wang C, Yao Y, Ma C, Ling Y: CCK-8 inhibits LPS-induced IL-1" production in pulmonary interstitial macrophages by modulating PKA, p38, and NF-.B pathway. Shock 27:678-686, 2007.
11. Boonstra A, Rajsbaum R, Holman M, Marques R, Asselin-Paturel C, Pereira JP, bates EEM, Akira S, Vieira P, Liu YJ, et al.: Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals. J Immunol 177:7551-7558, 2006.
12. Ghosh S: Regulation of inducible gene expression by the transcription factor NF-.B. Immunol Res 19:183-189, 1999.
13. Sakurai H, Chiba H, Miyoshi H, Sugita T, Yoriumi W: I.B kinases phos-phorylated NF0.B p65 subunit on serine 536 in the transactivation domain. J Biol Chem 274:30353-30356, 1999.
14. O'Garra A, Barrat FJ, Castro AG, Vicari A, Hawrylowicz C: Strategies for use of IL-10 or its antagonists in human disease. Immunol Rev 223:114-131, 2008.
15. Liu YW, Chen CC, Tseng HP, Chang WC: Lipopolysaccharide-induced tran-scriptional activation of interleukin-10 is mediated by MAPK- and NF-.BY induced CCAAT/enhancer-binding protein delta in mouse macrophages. Cell Signal 18:1492-1450, 2006.
16. Dong Q, Fan R, Zhao S, Wang Y: Over-expression of SOCS-3 gene promoters IL-10 production by JEG-3 trophoblast cells. Placenta 30:11-14, 2008.
17. Yoshimura A: Regulation of cytokine signaling by the SOCS and Spred family proteins. Keio J Med 58:73-83, 2009.
18. Berlato C, Cassatella MA, Kinjyo I, Gatto L, Yoshimura A, Bazzoni F: Involvement of suppressor of cytokine signaling-3 as a mediator of the inhibitory effect of IL-10 on lipopolysaccharide-induced macrophage activation. J Immunol 168:6404-6411, 2002.
19. Cavaillon JM, Adib-Conquy M: Monocytes/macrophages and sepsis. Crit Care Med 33:S506YS509, 2005.
20. Borovikova LV, Ivanova S, Zhang M, Yang H, Botchkina GI, Watkins LR, Wang H, Abumrad N, Eaton JW, Tracey KJ: Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature 405:458-462, 2000.
21. Sundy JS, Patel DD, Haynes BF: Cytokines in normal and pathogenic inflammatory response. In: Gallin JI, Synderman R, eds.: Inflammation: Basic Principles and Clinical Correlates. Philadelphia, PA: Lippincott Williams & Wilkins, pp 433-441, 1999.
22. Calandra T, Spiegel LA, metz CN, Bucala R: Macrophage migration inhibitory factor is a critical mediator of the activation of immune cells by endotoxins of gram-positive bacteria. Proc Natl Acad Sci USA 95:1183-1188, 1998.
23. Kolios G, Valatas V, manousou P, Xidakis C, Notas G, Kouroumalis E: Nitric oxide and MCP-1 regulation in LPS activated rat Kupffer cells. Mol Cell Biochem 319:91-98, 2008.
24. Calandra T, Echtenacher B, Roy DL, Pugin J, Metz CN, Hultner L, Heumann D, Mannel D, Bucala R, Glauser MP: Protection from septic shock by neutralization of macrophage migration inhibitory factor. Nat Med 6:164-170, 2000. (Pubitemid 30082360)
25. Ramnath RD, Ng SW, Guglielmotti A, Bhatia M: Role of MCP-1 in endotox-emia and sepsis. Int Immunopharmacol 8:810-818, 2008.