Effect of treadmill exercise on blood glucose, serum corticosterone levels and glucocorticoid receptor immunoreactivity in the hippocampus in chronic diabetic rats

Neurochemical Research

Volumn 36, Issue 2, 2011, Pages 281-287

  Hwang, In Koo ^a   Yi, Sun Shin ^a,b   Yoo, Ki Yeon ^c   Park, Ok Kyu ^c   Yan, Bingchun ^c   Song, Wook ^a   Won, Moo Ho ^d   Yoon, Yeo Sung ^a   Seong, Je Kyung ^a  

^a Seoul National University   (South Korea)

^b MARQUETTE UNIVERSITY   (United States)

^c Hallym University   (South Korea)

^d Kangwon National University   (South Korea)

Author keywords

Corticosteroid; Glucocorticoid receptor; Hippocampus; Immunohistochemistry; Treadmill exercise; Type 2 diabetes

Indexed keywords

CORTICOSTERONE; GLUCOCORTICOID RECEPTOR; GLUCOSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC DISEASE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DENTATE GYRUS; GLUCOSE BLOOD LEVEL; GRANULE CELL; HIPPOCAMPAL CA1 REGION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; TREADMILL EXERCISE; ZUCKER DIABETIC FATTY RAT;

ANIMALS; BLOOD GLUCOSE; CORTICOSTERONE; DIABETES MELLITUS, TYPE 2; FEMALE; HIPPOCAMPUS; HUMANS; MALE; PHYSICAL CONDITIONING, ANIMAL; RANDOM ALLOCATION; RATS; RATS, ZUCKER; RECEPTORS, GLUCOCORTICOID;

RATTUS;

EID: 78751604820     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-010-0315-z     Document Type: Article

References (48)

1. M Serrano Rios 1998 Relationship between obesity and the increased risk of major complications in non-insulin-dependent diabetes mellitus Eur J Clin Invest 28 Suppl 2 14 17 9777322 10.1046/j.1365-2362.1998.0280s2014.x
2. RB Goldberg 2000 Hyperlipidemia and cardiovascular risk factors in patients with type 2 diabetes Am J Manag Care 6 S682 S691 1:STN:280: DC%2BD3M%2FgvFWhtw%3D%3D 11183421
3. MC Carr JD Brunzell 2004 Abdominal obesity and dyslipidemia in the metabolic syndrome: importance of type 2 diabetes and familial combined hyperlipidemia in coronary artery disease risk J Clin Endocrinol Metab 89 2601 2607 1:CAS:528:DC%2BD2cXmtlGqtL0%3D 15181030 10.1210/jc.2004-0432 (Pubitemid 38766338)
4. LP Kozak M Rossmeisl 2002 Adiposity and the development of diabetes in mouse genetic models Ann N Y Acad Sci 967 80 87 1:CAS:528:DC%2BD38XlvVKqurs%3D 12079838 10.1111/j.1749-6632.2002.tb04266.x
5. EH Leiter PC Reifsnyder 2004 Differential levels of diabetogenic stress in two new mouse models of obesity and type 2 diabetes Diabetes 53 1 S4 S11 1:CAS:528:DC%2BD2cXhtlGqsLo%3D 14749259 10.2337/diabetes.53.2007.S4
6. D Chen MW Wang 2005 Development and application of rodent models for type 2 diabetes Diabetes Obes Metab 7 307 317 15955116 10.1111/j.1463-1326.2004. 00392.x (Pubitemid 40916572)
7. MC Appel BA Schibly JA Kamara RL Sorenson 1979 Adrenal gland involvement in mice with hereditary obesity and diabetes mellitus. Morphological studies Diabetologia 16 391 398 1:CAS:528:DyaE1MXkslaksLc%3D 467849 10.1007/BF01223160 (Pubitemid 10231982)
8. MW Schwartz AM Strack MF Dallman 1997 Evidence that elevated plasma corticosterone levels are the cause of reduced hypothalamic corticotrophin- releasing hormone gene expression in diabetes Regul Pept 72 105 112 1:CAS:528:DyaK1cXmtlGrtg%3D%3D 9652969 10.1016/S0167-0115(97)01043-4 (Pubitemid 28053866)
9. R Pasquali V Vicennati A Gambineri 2002 Adrenal and gonadal function in obesity J Endocrinol Invest 25 893 898 1:CAS:528:DC%2BD3sXmsFOrtQ%3D%3D 12508952
10. S Noguchi Y Ohno N Aoki 2007 Adrenocortical insufficiency in Otsuka Long-Evans Tokushima fatty rats, a type 2 diabetes mellitus model Metabolism 56 1326 1333 1:CAS:528:DC%2BD2sXhtVOgu73M 17884440 10.1016/j.metabol.2007.05.021 (Pubitemid 47404594)
11. A Convit MJ de Leon C Tarshish, et al. 1997 Specific hippocampal volume reductions in individuals at risk for Alzheimer's disease Neurobiol Aging 18 131 138 1:STN:280:DyaK2svgtlGgsQ%3D%3D 9258889 10.1016/S0197-4580(97)00001-8 (Pubitemid 27355930)
12. CL Leibson WA Rocca VA Hanson, et al. 1997 Risk of dementia among persons with diabetes mellitus: a population-based cohort study Am J Epidemiol 145 301 308 1:STN:280:DyaK2s7ovVKkuw%3D%3D 9054233
13. BE Leonard 2007 Inflammation, depression and dementia: are they connected? Neurochem Res 32 1749 1756 1:CAS:528:DC%2BD2sXhtVGmsL3F 17705097 10.1007/s11064-007-9385-y (Pubitemid 47428863)
14. MA Kamal Y Tan JP Seale X Qu 2009 Targeting BuChE-inflammatory pathway by SK0506 to manage type 2 diabetes and Alzheimer disease Neurochem Res 34 2163 2169 1:CAS:528:DC%2BD1MXmvFSgs78%3D 10.1007/s11064-009-0011-z
15. BS McEwen AM Magarinos 1997 Stress effects on morphology and function of the hippocampus Ann N Y Acad Sci 821 271 284 1:STN:280:DyaK2szotVymtg%3D%3D 9238211 10.1111/j.1749-6632.1997.tb48286.x (Pubitemid 27343028)
16. N Sousa OF Almeida 2002 Corticosteroids: sculptors of the hippocampal formation Rev Neurosci 13 59 84 1:CAS:528:DC%2BD38XovVGls74%3D 12013026
17. SM Korte 2001 Corticosteroids in relation to fear, anxiety and psychopathology Neurosci Biobehav Rev 25 117 142 1:CAS:528:DC%2BD3MXivFarur0%3D 11323078 10.1016/S0149-7634(01)00002-1 (Pubitemid 32377167)
18. M Kawata K Matsuda M Nishi H Ogawa I Ochiai 2001 Intracellular dynamics of steroid hormone receptor Neurosci Res 40 197 203 1:CAS:528: DC%2BD3MXltVehsrY%3D 11448510 10.1016/S0168-0102(01)00253-X (Pubitemid 32633831)
19. C Kellendonk P Gass O Kretz G Schutz F Tronche 2002 Corticosteroid receptors in the brain: gene targeting studies Brain Res Bull 57 73 83 1:CAS:528:DC%2BD38XhtVKkt7g%3D 11827739 10.1016/S0361-9230(01)00638-4 (Pubitemid 34097772)
20. MM Sánchez CO Ladd PM Plotsky 2001 Early adverse experience as a developmental risk factor for later psychopathology: evidence from rodent and primate models Dev Psychopathol 13 419 449 11523842 10.1017/S0954579401003029 (Pubitemid 33406337)
21. AL Hevener D Reichart J Olefsky 2000 Exercise and thiazolidinedione therapy normalize insulin action in the obese Zucker fatty rat Diabetes 49 2154 2159 1:CAS:528:DC%2BD3cXos1ejsLg%3D 11118020 10.2337/diabetes.49.12.2154
22. R Pold LS Jensen N Jessen, et al. 2005 Long-term AICAR administration and exercise prevents diabetes in ZDF rats Diabetes 54 928 934 1:CAS:528: DC%2BD2MXjtFWntrc%3D 15793229 10.2337/diabetes.54.4.928 (Pubitemid 40446305)
23. MB Flores MF Fernandes ER Ropelle, et al. 2006 Exercise improves insulin and leptin sensitivity in hypothalamus of Wistar rats Diabetes 55 2554 2561 1:CAS:528:DC%2BD28XpsVOrur0%3D 16936204 10.2337/db05-1622 (Pubitemid 44871156)
24. P Reisi H Alaei S Babri MR Sharifi G Mohaddes E Soleimannejad 2009 Determination of the extracellular basal levels of glutamate and GABA at dentate gyrus of streptozotocin-induced diabetic rats Pathophysiology 16 63 66 1:CAS:528:DC%2BD1MXmtVarur0%3D 19372035 10.1016/j.pathophys.2009.03.003
25. RV Contarteze B Manchado Fde CA Gobatto MA De Mello 2008 Stress biomarkers in rats submitted to swimming and treadmill running exercises Comp Biochem Physiol A Mol Integr Physiol 151 415 422 17428717 10.1016/j.cbpa.2007. 03.005
26. JE Campbell MA Király DJ Atkinson AM D'souza M Vranic MC Riddell 2010 Regular exercise prevents the development of hyperglucocorticoidemia via adaptations in the brain and adrenal glands in male Zucker diabetic fatty rats Am J Physiol Regul Integr Comp Physiol 299 R168 R176 1:CAS:528: DC%2BC3cXpsVOrtrY%3D 20393161
27. IK Hwang SS Yi YN Kim, et al. 2008 Reduced hippocampal cell differentiation in the subgranular zone of the dentate gyrus in a rat model of type II diabetes Neurochem Res 33 394 400 1:CAS:528:DC%2BD1cXhs1ahsro%3D 17712629 10.1007/s11064-007-9440-8 (Pubitemid 351230439)
28. SS Yi IK Hwang KY Yoo, et al. 2009 Effects of treadmill exercise on cell proliferation and differentiation in the subgranular zone of the dentate gyrus in a rat model of type II diabetes Neurochem Res 34 1039 1046 1:CAS:528:DC%2BD1cXhtlansL3M 18982449 10.1007/s11064-008-9870-y
29. Paxinos G, Watson C (2007) The rat brain in stereotaxic coordinates. Elsevier Academic Press, Amsterdam
30. M Colombo S Gregersen M Kruhoeffer, et al. 2005 Prevention of hyperglycemia in Zucker diabetic fatty rats by exercise training: effects on gene expression in insulin-sensitive tissues determined by high-density oligonucleotide microarray analysis Metabolism 54 1571 1581 1:CAS:528: DC%2BD2MXht1Oms7jK 16311088 10.1016/j.metabol.2005.06.003 (Pubitemid 41728147)
31. MA Király HE Bates JT Yue, et al. 2007 Attenuation of type 2 diabetes mellitus in the male Zucker diabetic fatty rat: the effects of stress and non-volitional exercise Metabolism 56 732 744 17512304 10.1016/j.metabol. 2006.12.022 (Pubitemid 46734079)
32. MA Király HE Bates NA Kaniuk, et al. 2008 Swim training prevents hyperglycemia in ZDF rats: mechanisms involved in the partial maintenance of beta-cell function Am J Physiol Endocrinol Metab 294 E271 E283 18029442 10.1152/ajpendo.00476.2007 (Pubitemid 351231453)
33. AC Smith KL Mullen KA Junkin, et al. 2007 Metformin and exercise reduce muscle FAT/CD36 and lipid accumulation and blunt the progression of high-fat diet-induced hyperglycemia Am J Physiol Endocrinol Metab 293 E172 E181 1:CAS:528:DC%2BD2sXosV2msb8%3D 17374701 10.1152/ajpendo.00677.2006 (Pubitemid 47105931)
34. B Beck JP Max S Richy A Stricker-Krongrad 2004 Feeding response to a potent prolactin-releasing peptide agonist in lean and obese Zucker rats Brain Res 1016 135 138 1:CAS:528:DC%2BD2cXltl2ht74%3D 15234262 10.1016/j.brainres. 2004.05.002 (Pubitemid 38834282)
35. M van der Graaf SW Janssen JJ van Asten, et al. 2004 Metabolic profile of the hippocampus of Zucker Diabetic Fatty rats assessed by in vivo 1H magnetic resonance spectroscopy NMR Biomed 17 405 410 15386626 10.1002/nbm.896 (Pubitemid 39335179)
36. JP Vora SM Zimsen DC Houghton S Anderson 1996 Evolution of metabolic and renal changes in the ZDF/Drt-fa rat model of type II diabetes J Am Soc Nephrol 7 113 117 1:CAS:528:DyaK28Xhs1Shur4%3D 8808117
37. GJ Etgen BA Oldham 2000 Profiling of Zucker diabetic fatty rats in their progression to the overt diabetic state Metabolism 49 684 688 1:CAS:528:DC%2BD3cXjsVWlu7w%3D 10831184 10.1016/S0026-0495(00)80049-9
38. Riddell MC, Tsiani E, Ruderman NB, Vranic M (2003) The endocrine system: metabolic effects of the pancreatic, adrenal, thyroidal and growth hormones. In: Tripton CM (ed) Exercise Physiology-People and Ideas. Oxford University Press, New York, pp 361-422
39. RS Surwit MS Schneider 1993 Role of stress in the etiology and treatment of diabetes mellitus Psychosom Med 55 380 393 1:STN:280:DyaK2c%2Fit1yisg%3D%3D 8105502
40. B Catargi V Rigalleau A Poussin, et al. 2003 Occult Cushing's syndrome in type-2 diabetes J Clin Endocrinol Metab 88 5808 5813 1:CAS:528: DC%2BD3sXhtVSgsr3P 14671173 10.1210/jc.2003-030254 (Pubitemid 38033055)
41. E Kainuma M Watanabe C Tomiyama-Miyaji, et al. 2009 Association of glucocorticoid with stress-induced modulation of body temperature, blood glucose and innate immunity Psychoneuroendocrinology 34 1459 1468 1:CAS:528: DC%2BD1MXht1Ogtb3P 19493627 10.1016/j.psyneuen.2009.04.021
42. ME Keller-Wood MF Dallman 1984 Corticosteroid inhibition of ACTH secretion Endocr Rev 5 1 24 1:CAS:528:DyaL2cXhvVGrtrg%3D 6323158 10.1210/edrv-5-1-1
43. L Jacobson R Sapolsky 1991 The role of the hippocampus in feedback regulation of the hypothalamic-pituitary-adrenocortical axis Endocr Rev 12 118 134 1:STN:280:DyaK3MzgtFWisw%3D%3D 2070776 10.1210/edrv-12-2-118
44. RM Sapolsky LC Krey BS McEwen 1984 Stress down-regulates corticosterone receptors in a site-specific manner in the brain Endocrinology 114 287 292 1:CAS:528:DyaL2cXksFGqtw%3D%3D 6690273 10.1210/endo-114-1-287
45. HM Chao DC Blanchard RJ Blanchard BS McEwen RR Sakai 1993 The effect of social stress on hippocampal gene expression Mol Cell Neurosci 4 543 548 1:CAS:528:DyaK2cXhsFCjtbY%3D 19912962 10.1006/mcne.1993.1067 (Pubitemid 23340709)
46. BS McEwen H Cameron HM Chao, et al. 1993 Adrenal steroids and plasticity of hippocampal neurons: toward an understanding of underlying cellular and molecular mechanisms Cell Mol Neurobiol 13 457 482 1:CAS:528: DyaK2cXpsF2lsg%3D%3D 8252613 10.1007/BF00711583 (Pubitemid 23311420)
47. BS McEwen RM Sapolsky 1995 Stress and cognitive function Curr Opin Neurobiol 5 205 216 1:CAS:528:DyaK2MXlsVGitL4%3D 7620309 10.1016/0959-4388(95) 80028-X
48. IK Hwang SS Yi W Song MH Won YS Yoon JK Seong 2010 Effects of age and treadmill exercise in chronic diabetic stages on neuroblast differentiation in a rat model of type 2 diabetes Brain Res 1341 63 71 1:CAS:528: DC%2BC3cXntlaks74%3D 20005869 10.1016/j.brainres.2009.12.009