A mammalian functional-genetic approach to characterizing cancer therapeutics

Nature Chemical Biology

Volumn 7, Issue 2, 2011, Pages 92-100

  Jiang, Hai ^a   Pritchard, Justin R ^a   Williams, Richard T ^b   Lauffenburger, Douglas A ^a,c   Hemann, Michael T ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c USA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 TERT BUTYL 3 [6 (3,5 DIMETHOXYPHENYL) 2 (4 DIETHYLAMINOBUTYLAMINO)PYRIDO[2,3 D]PYRIMIDIN 7 YL]UREA; 2 (1H INDAZOL 4 YL) 6 (4 METHANESULFONYL 1 PIPERAZINYLMETHYL) 4 MORPHOLINOTHIENO[3,2 D]PYRIMIDINE; 2 METHOXYESTRADIOL; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; 6 (1,3 DIOXO 1H,3H BENZO[DE]ISOQUINOLIN 2 YL) N HYDROXYHEXANAMIDE; ANTINEOPLASTIC AGENT; BENDAMUSTINE; BIIB 021; BUSULFAN; CAMPTOTHECIN; CARBOPLATIN; CARMUSTINE; CHLORAMBUCIL; CISPLATIN; CY 190602; DAUNORUBICIN; DOXORUBICIN; ETOPOSIDE; FLUOROURACIL; GEMCITABINE; HYDROXYUREA; MELPHALAN; METHOTREXATE; MITOMYCIN C; MITOXANTRONE; PACLITAXEL; SHORT HAIRPIN RNA; TEMOZOLOMIDE; THIOTEPA; TIOGUANINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VER 50589; VINBLASTINE; VINCRISTINE; ZEBULARINE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG CLASSIFICATION; DRUG MECHANISM; DRUG SCREENING; DRUG SENSITIVITY; DRUG STRUCTURE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RNA INTERFERENCE;

MAMMALIA;

EID: 78751567879     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.503     Document Type: Article

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