Targeted inactivation of Kinesin-1 in pancreatic β-cells in vivo leads to insulin secretory deficiency

Diabetes

Volumn 60, Issue 1, 2011, Pages 320-330

  Cui, Ju ^a   Wang, Zai ^a   Cheng, Qianni ^b   Lin, Raozhou ^a   Zhang, Xin Mei ^a   Leung, Po Sing ^b   Copeland, Neal G ^c   Jenkins, Nancy A ^c   Yao, Kwok Ming ^a   Huang, Jian Dong ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; GLUCOSE; INSULIN; KINESIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL COMPOSITION; CELL COUNT; CELL LEVEL; CELL ORGANELLE; CELL PROLIFERATION; CELL SIZE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DIET RESTRICTION; ENZYME INACTIVATION; GENE; GENE INACTIVATION; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; GROWTH RETARDATION; HYPERGLYCEMIA; INSULIN BLOOD LEVEL; INSULIN DEFICIENCY; INSULIN RELEASE; INSULIN SENSITIVITY; INSULIN VESICLE; KIF5B GENE; KNOCKOUT MOUSE; MALE; MOUSE; NEWBORN; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TRANSGENIC MOUSE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; DNA PRIMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENOTYPE; HUMANS; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; KINESIN; MALE; MICE; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES, ANTISENSE; PEPTIDE FRAGMENTS;

EID: 78751513648     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db09-1078     Document Type: Article

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