Protein stress? pDCs go Toll-free

Blood

Volumn 117, Issue 2, 2011, Pages 376-377

  Dhodapkar, Madhav V ^a  

^a YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BORTEZOMIB; CELL PROTEIN; INTERFERON; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR;

APOPTOSIS; AUTOIMMUNITY; CANCER CELL; CELL DEATH; CELL FUNCTION; CELL SURVIVAL; ENDOPLASMIC RETICULUM; MYELOMA CELL; NOTE; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL;

EID: 78751475774     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-11-315838     Document Type: Note

References (10)

1. Hirai M, Kadowaki N, Kitawaki T, et al. Bortezomib suppresses function and survival of plasmacytoid dendritic cells by targeting intracellular trafficking of Toll-like receptors and endoplasmic reticulum homeostasis. Blood. 2011;117(2):500-509.
2. Steinman RM, Banchereau J. Taking dendritic cells into medicine. Nature. 2007;449(7161):419-426.
3. Blasius AL, Beutler B. Intracellular toll-like receptors. Immunity. 2010;32(3):305-315.
4. Iwakoshi NN, Pypaert M, Glimcher LH. The transcription factor XBP-1 is essential for the development and survival of dendritic cells. J Exp Med. 2007;204(10):2267-2275. (Pubitemid 47529314)
5. Todd DJ, Lee AH, Glimcher LH. The endoplasmic reticulum stress response in immunity and autoimmunity. Nat Rev Immunol. 2008;8(9):663-674.
6. Richardson PG, Mitsiades C, Hideshima T, Anderson KC. Bortezomib: proteasome inhibition as an effective anticancer therapy. Annu Rev Med. 2006;57:33-47. (Pubitemid 43261977)
7. Lee AH, Iwakoshi NN, Anderson KC, Glimcher LH. Proteasome inhibitors disrupt the unfolded protein response in myeloma cells. Proc Natl Acad Sci U S A. 2003;100(17):9946-9951. (Pubitemid 37087048)
8. Kukreja A, Hutchinson A, Mazumder A, et al. Bortezomib disrupts tumour-dendritic cell interactions in myeloma and lymphoma: therapeutic implications. Br J Haematol. 2007;136(1):106-110.
9. Lande R, Gilliet M. Plasmacytoid dendritic cells: key players in the initiation and regulation of immune responses. Ann N Y Acad Sci. 2010;1183:89-103.
10. Chauhan D, Singh AV, Brahmandam M, et al. Functional interaction of plasmacytoid dendritic cells with multiple myeloma cells: a therapeutic target. Cancer Cell. 2009;16(4):309-323.