Formulation optimization of metronidazole loaded chitosan microspheres for wound management by 3-factor, 3-level box-behnken design

Micro and Nanosystems

Volumn 2, Issue 2, 2010, Pages 70-77

  Singh, Deependra ^a   Singh, Manju Rawat ^a   Saraf, Swarnlata ^a   Dixit, V K ^b   Saraf, S ^a  

^a PT RAVISHANKAR SHUKLA UNIVERSITY   (India)

^b DR H S GOUR UNIVERSITY   (India)

Author keywords

Box behnken design; Chitosan; Metronidazole; Microspheres; Wound healing

Indexed keywords

3D SURFACE; ANTI-MICROBIAL ACTIVITY; BOX-BEHNKEN DESIGN; CHITOSAN MICROSPHERES; CONTROLLED RELEASE; CROSS LINKING AGENTS; DEPENDENT VARIABLES; DRUG RELEASE; ENTRAPMENT EFFICIENCY; FORMULATION OPTIMIZATION; INDEPENDENT VARIABLES; KINETIC MODELS; MEAN DIAMETER; METRONIDAZOLE; MULTIPLE RESPONSE OPTIMIZATION; NON-FICKIAN; OPTIMAL FORMULATION; RELEASE KINETICS; RELEASE PATTERN; RESPONSE SURFACE METHODOLOGY; RSM OPTIMIZATION; SECOND-ORDER POLYNOMIAL EQUATIONS; SIZE RANGES; TRIPOLYPHOSPHATES; WOUND HEALING; WOUND MANAGEMENT;

CHITOSAN; DESIGN; DRUG PRODUCTS; MICROSPHERES; OPTIMIZATION; POLYNOMIALS; SCANNING ELECTRON MICROSCOPY; THREE DIMENSIONAL;

CHITIN;

EID: 78651524020     PISSN: 18764029     EISSN: 18764037     Source Type: Journal    
DOI: 10.2174/1876402911002020070     Document Type: Article

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