Mucoadhesive microspheres of propranolol hydrochloride for nasal delivery

Indian Journal of Pharmaceutical Sciences

Volumn 69, Issue 3, 2007, Pages 402-407

  Dandagi, P ^a   Mastiholimath, V ^a   Gadad, A ^a   Iliger, S ^a  

^a K L E S S COLLEGE OF PHARMACY   (India)

Author keywords

Gelatin A; Microspheres; Propranolol HCl and chitosan

Indexed keywords

BUFFER; CHITOSAN; COPOLYMER; GELATINASE A; GLUTARALDEHYDE; MICROSPHERE; PHOSPHATE; POLYMER; PROPRANOLOL;

ANALYTIC METHOD; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM; DRUG EFFICACY; DRUG METABOLISM; DRUG RELEASE; EMULSION; MALE; MIGRAINE; NONHUMAN; PARTICLE SIZE; RAT; SUSTAINED DRUG RELEASE;

EID: 34548505050     PISSN: 0250474X     EISSN: None     Source Type: Journal    
DOI: 10.4103/0250-474X.34550     Document Type: Article

References (19)

1. th ed. London (UK); Churchill Livingstone: 1999.
2. Huang CH, Kimura R, Nassar RB. Hussain A. Mechanism of nasal absorption of drugs I: Physicochemical parameters influencing the rate of in situ nasal absorption of drugs in rats. J Pharm Sci 1985;74:608-11.
3. Rao PR, Reddy MN, Ramakrishna S, Prakash V. Comparative in vivo evaluation of propranolol hydrochloride after oral and transdermal administration in rabbits. Eur J Pharm Biopharm 2003;56:81-5.
4. Ugwoke MI, Verbeke N, Kinget R. The biopharmaceutical aspects of nasal mucoadhesive drug delivery. J Pharm Pharmacol 2001;53:3-21.
5. Pisal S, Shelke V, Mahadik K, Kadam S. Effect of organogel components on in vitro nasal delivery of propranolol hydrochloride. AAPS Pharm Sci Tech 2004;5:63.
6. Chein YW, Su KS, Chang SF. Nasal systemic drug delivery. Marcel Dekker Inc: New York; 1989.
7. th ed. European directorate for the quality of medicine. London; 2001. p. 1236.
8. Morimoto K, Katsumata H, Toshiyuki Y, Iwanaga K, Kakemi M, Tabata Y, et al. Evaluation of gelatin microspheres for nasal and intramuscular administration of solmon calcitonin. Eur J Pharm. Sci 2001;13:179-85.
9. Sankar C, Mishra B. Development and in vitro evaluation of gelatin A microspheres of Ketorolac tromethamine for intranasal administration. Acta Pharm 2003;53:101-10.
10. Kasper FK, Kushibiki T, Kimura Y, Antonios G, Tabata Y. In vivo release of plasmid DNA from composites of oligo (poly (ethylene glycol) fumarate) and cationized gelatin microspheres. J Control Release 2005;107:547-61.
11. Shirui M, Chen J, Wei Z, Liu H, Bi D. Intranasal administration of melatonin starch microspheres. Int J Pharm 2004;272:37-43.
12. th ed. New Delhi; BI Waverly Pvt Ltd: 1996.
13. Huang YC, Yen MK, Chiang CH. Formulation factors in preparing BTM-chitosan microspheres by spray drying method. Int J Pharm 2000;242:239-42.
14. Tabassi SA, Razavi N. Preparation and characterization of albumin microspheres encapsulated with propranolol hydrochloride. DARU 2003;11:137-41.
15. Patel JK, Patel RP, Amin AF, Patel MM. Formulation and evaluation of mucoadhesive glipizide microspheres. AAPS Pharm Sci Tech 2005;6:E49-55.
16. Soppimath KS, Aminbhavi TM. Water transport and drug release study from cross linked polyacrylamide grafted guar gum hydrogel microspheres for the controlled release application. Eur J Pharm Biopharm 2002;53:87-9.
17. Fandueanu G, Constantin M, Dalpiaz A, Bortolotti F, Cortesi R, Ascenzi P, et al. Preparation and characterization of starch/ cyclodextrin bioadhesive microspheres as platform for nasal administration of Gabexate Mesylate (Foy®) in allergic rhinitis treatment. Biomaterial 2004;25:159-70.
18. Rao YM, Devi KM, Rameshachary B. Stability study of Refampicin mucoadhesive nasal drops. Indian J Pharm Sci 1999;61:366-70.
19. Kulkarni GT, Gosthamarajan K, Suresh B. Stability testing of pharmaceutical products: An overview. Indian J Pharm Edu 2004;38:194-202-20.