Drug release from PLGA microspheres attached to solids using supercritical CO2

Journal of Biomaterials Applications

Volumn 25, Issue 5, 2011, Pages 401-412

  Mulia, Kamarza ^a,b   Witkamp, Geert Jan ^b   Dawes, Gwen J S ^c   Fratila Apachitei, Lidy Elena ^c   Apachitei, Iulian ^c   Duszczyk, Jurek ^c   Pellikaan, Hubert ^d  

^a UNIVERSITY OF INDONESIA   (Indonesia)

^b DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^c DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^d Nextstep Pharma BV   (Netherlands)

Author keywords

continuous release; dexamethasone; drug delivery system; microspheres; orthopedic implant; PLGA; supercritical CO2

Indexed keywords

CONTINUOUS RELEASE; DEXAMETHASONES; DRUG DELIVERY SYSTEM; ORTHOPEDIC IMPLANT; PLGA; SUPERCRITICAL CO2;

ALLOYS; BIODEGRADABLE POLYMERS; CARBON DIOXIDE; CYTOTOXICITY; DRUG DELIVERY; DRUG PRODUCTS; FUNCTIONAL POLYMERS; GLASS; POLYMER BLENDS; POROUS PLATES; SUPERCRITICAL FLUID EXTRACTION;

MICROSPHERES;

BIOMATERIAL; CARBON DIOXIDE; CHROMIUM DERIVATIVE; DEXAMETHASONE; GLASS; LACTIC ACID; MICROSPHERE; POLYGLYCOLIC ACID; POLYLACTIC ACID POLYGLYCOLIC ACID COPOLYMER; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ARTICLE; DRUG DELIVERY SYSTEM; HUMAN; IN VITRO STUDY; MATERIALS TESTING; PROSTHESES AND ORTHOSES; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY;

BIOCOMPATIBLE MATERIALS; CARBON DIOXIDE; CHROMIUM ALLOYS; COATED MATERIALS, BIOCOMPATIBLE; DEXAMETHASONE; DRUG DELIVERY SYSTEMS; GLASS; HUMANS; LACTIC ACID; MATERIALS TESTING; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; POLYGLYCOLIC ACID; PROSTHESES AND IMPLANTS; SURFACE PROPERTIES;

EID: 78651520460     PISSN: 08853282     EISSN: 15308022     Source Type: Journal    
DOI: 10.1177/0885328209354365     Document Type: Article

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