Painful heat reveals hyperexcitability of the temporal pole in interictal and ictal migraine states

Cerebral Cortex

Volumn 21, Issue 2, 2011, Pages 435-448

  Moulton, E A ^a   Becerra, L ^a,b   Maleki, N ^a   Pendse, G ^a   Tully, S ^a   Hargreaves, R ^c   Burstein, R ^d   Borsook, D ^a,b  

^a MCLEAN HOSPITAL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

DTI; fMRI; headache; pain; temporal lobe

Indexed keywords

ADULT; ARTICLE; BRAIN CORTEX; BRAIN REGION; CLINICAL ARTICLE; CONTROLLED STUDY; DIFFUSION TENSOR IMAGING; DISEASE EXACERBATION; EXCITABILITY; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HEAT; HUMAN; MALE; MIGRAINE; PHYSIOLOGICAL PROCESS; PRIORITY JOURNAL; TEMPORAL LOBE; WHITE MATTER;

ADULT; BRAIN MAPPING; DIFFUSION MAGNETIC RESONANCE IMAGING; FEMALE; HOT TEMPERATURE; HUMANS; HYPERALGESIA; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MIGRAINE DISORDERS; OXYGEN; PAIN THRESHOLD; TEMPORAL LOBE;

EID: 78651516735     PISSN: 10473211     EISSN: 14602199     Source Type: Journal    
DOI: 10.1093/cercor/bhq109     Document Type: Article

References (114)

1. Afra J, Mascia A, Gerard P, Maertens de Noordhout A, Schoenen J. 1998. Interictal cortical excitability in migraine: a study using transcranial magnetic stimulation of motor and visual cortices. Ann Neurol. 44:209-215.
2. Afra J, Proietti Cecchini A, Sandor PS, Schoenen J. 2000. Comparison of visual and auditory evoked cortical potentials in migraine patients between attacks. Clin Neurophysiol. 111:1124-1129.
3. Afridi SK, Giffin NJ, Kaube H, Friston KJ, Ward NS, Frackowiak RS, Goadsby PJ. 2005. A positron emission tomographic study in spontaneous migraine. Arch Neurol. 62:1270-1275.
4. Afridi SK, Matharu MS, Lee L, Kaube H, Friston KJ, Frackowiak RS, Goadsby PJ. 2005. A PET study exploring the laterality of brainstem activation in migraine using glyceryl trinitrate. Brain. 128:932-939.
5. Ambrosini A, Rossi P, De Pasqua V, Pierelli F, Schoenen J. 2003. Lack of habituation causes high intensity dependence of auditory evoked cortical potentials in migraine. Brain. 126:2009-2015.
6. Anderson WS, Sheth RN, Bencherif B, Frost JJ, Campbell JN. 2002. Naloxone increases pain induced by topical capsaicin in healthy human volunteers. Pain. 99:207-216.
7. Antal A, Temme J, Nitsche MA, Varga ET, Lang N, Paulus W. 2005. Altered motion perception in migraineurs: evidence for interictal cortical hyperexcitability. Cephalalgia. 25:788-794.
8. Apkarian AV, Hodge CJ. 1989. Primate spinothalamic pathways: iII. Thalamic terminations of the dorsolateral and ventral spinothalamic pathways. J Comp Neurol. 288:493-511.
9. Asari T, Konishi S, Jimura K, Chikazoe J, Nakamura N, Miyashita Y. 2008. Right temporopolar activation associated with unique perception. Neuroimage. 41:145-152.
10. Aurora SK, Kori SH, Barrodale P, McDonald SA, Haseley D. 2006. Gastric stasis in migraine: more than just a paroxysmal abnormality during a migraine attack. Headache. 46:57-63.
11. Backer M, Sander D, Hammes MG, Funke D, Deppe M, Conrad B, Tolle TR. 2001. Altered cerebrovascular response pattern in interictal migraine during visual stimulation. Cephalalgia. 21:611-616.
12. Bahra A, Matharu MS, Buchel C, Frackowiak RS, Goadsby PJ. 2001. Brainstem activation specific to migraine headache. Lancet. 357:1016-1017.
13. Bartolomei F, Barbeau E, Gavaret M, Guye M, McGonigal A, Regis J, Chauvel P. 2004. Cortical stimulation study of the role of rhinal cortex in deja vu and reminiscence of memories. Neurology. 63:858-864.
14. Becerra L, Breiter HC, Wise R, Gonzalez RG, Borsook D. 2001. Reward circuitry activation by noxious thermal stimuli. Neuron. 32: 927-946.
15. Becerra L, Morris S, Bazes S, Gostic R, Sherman S, Gostic J, Pendse G, Moulton E, Scrivani S, Keith D, et al. 2006. Trigeminal neuropathic pain alters responses in CNS circuits to mechanical (brush) and thermal (cold and heat) stimuli. J Neurosci. 26:10646-10657.
16. Bencherif B, Fuchs PN, Sheth R, Dannals RF, Campbell JN, Frost JJ. 2002. Pain activation of human supraspinal opioid pathways as demonstrated by [11C]-carfentanil and positron emission tomography (PET). Pain. 99:589-598.
17. Bigal ME, Lipton RB, Cohen J, Silberstein SD. 2003. Epilepsy and migraine. Epilepsy Behav. 4(Suppl 2):S13-S24.
18. Bingel U, Quante M, Knab R, Bromm B, Weiller C, Buchel C. 2002. Subcortical structures involved in pain processing: evidence from single-trial fMRI. Pain. 99:313-321.
19. Bolay H, Reuter U, Dunn AK, Huang Z, Boas DA, Moskowitz MA. 2002. Intrinsic brain activity triggers trigeminal meningeal afferents in a migraine model. Nat Med. 8:136-142.
20. Borsook D, DaSilva AF, Ploghaus A, Becerra L. 2003. Specific and somatotopic functional magnetic resonance imaging activation in the trigeminal ganglion by brush and noxious heat. J Neurosci. 23:7897-7903.
21. Bougeard R, Fischer C. 2002. The role of the temporal pole in auditory processing. Epileptic Disord. 4(Suppl 1):S29-S32.
22. Boyle R, Behan PO, Sutton JA. 1990. A correlation between severity of migraine and delayed gastric emptying measured by an epigastric impedance method. Br J Clin Pharmacol. 30:405-409.
23. Burstein R, Jakubowski M, Garcia-Nicas E, Kainz V, Bajwa Z, Hargreaves R, Becerra L, Borsook D. Forthcoming. Thalamic sensitization transforms localized pain into widespread allodynia and hyperalgesia. Ann Neurol.
24. Burstein R, Yarnitsky D, Goor-Aryeh I, Ransil BJ, Bajwa ZH. 2000. An association between migraine and cutaneous allodynia. Ann Neurol. 47:614-624.
25. Calandre EP, Bembibre J, Arnedo ML, Becerra D. 2002. Cognitive disturbances and regional cerebral blood flow abnormalities in migraine patients: their relationship with the clinical manifestations of the illness. Cephalalgia. 22:291-302.
26. Casey KL, Tran TD. 2006. Cortical mechanisms mediating acute and chronic pain in humans. In: Cervero F, Jensen TS, editors. Handbook of clinical neurology. Edinburgh, New York: Elsevier. p. 159-177.
27. Castro MJ, Stam AH, Lemos C, de Vries B, Vanmolkot KR, Barros J, Terwindt GM, Frants RR, Sequeiros J, Ferrari MD, et al. 2009. First mutation in the voltage-gated Nav1.1 subunit gene SCN1A with co-occurring familial hemiplegic migraine and epilepsy. Cephalalgia. 29:308-313.
28. Charles A. 2009. Advances in the basic and clinical science of migraine. Ann Neurol. 65:491-498.
29. Chow KL. 1950. A retrograde cell degeneration study of the cortical projection field of the pulvinar in the monkey. J Comp Neurol. 93:313-340.
30. Clarke S, Bellmann Thiran A, Maeder P, Adriani M, Vernet O, Regli L, Cuisenaire O, Thiran JP. 2002. What and where in human audition: selective deficits following focal hemispheric lesions. Exp Brain Res. 147:8-15.
31. Coppola G, Ambrosini A, Di Clemente L, Magis D, Fumal A, Gerard P, Pierelli F, Schoenen J. 2007. Interictal abnormalities of gamma band activity in visual evoked responses in migraine: an indication of thalamocortical dysrhythmia? Cephalalgia. 27:1360-1367.
32. DaSilva AF, Granziera C, Snyder J, Hadjikhani N. 2007. Thickening in the somatosensory cortex of patients with migraine. Neurology. 69:1990-1995.
33. De Felice M, Ossipov MH, Wang R, Lai J, Chichorro J, Meng I, Dodick DW, Vanderah TW, Dussor G, Porreca F. 2010. Triptan-induced latent sensitization: a possible basis for medication overuse headache. Ann Neurol. 67:325-337.
34. de Hoon JN, Willigers JM, Troost J, Struijker-Boudier HA, van Bortel LM. 2003. Cranial and peripheral interictal vascular changes in migraine patients. Cephalalgia. 23:96-104.
35. Demarquay G, Royet JP, Giraud P, Chazot G, Valade D, Ryvlin P. 2006. Rating of olfactory judgements in migraine patients. Cephalalgia. 26:1123-1130.
36. Demarquay G, Royet JP, Mick G, Ryvlin P. 2008. Olfactory hypersen-sitivity in migraineurs: a H(2)(15)OPET study. Cephalalgia. 28: 1069-1080.
37. Deprez L, Peeters K, Van Paesschen W, Claeys KG, Claes LR, Suls A, Audenaert D, Van Dyck T, Goossens D, Del-Favero J, et al. 2007. Familial occipitotemporal lobe epilepsy and migraine with visual aura: linkage to chromosome 9q. Neurology. 68:1995-2002.
38. Derbyshire SW, Jones AK, Gyulai F, Clark S, Townsend D, Firestone LL. 1997. Pain processing during three levels of noxious stimulation produces differential patterns of central activity. Pain. 73:431-445.
39. De Simone R, Ranieri A, Marano E, Beneduce L, Ripa P, Bilo L, Meo R, Bonavita V. 2007. Migraine and epilepsy: clinical and pathophysio-logical relations. Neurol Sci. 28(Suppl 2):S150-S155.
40. De Tommaso M, Difruscolo O, Sardaro M, Libro G, Pecoraro C, Serpino C, Lamberti P, Livrea P. 2007. Effects of remote cutaneous pain on trigeminal laser-evoked potentials in migraine patients. J Headache Pain. 8:167-174.
41. De Tommaso M, Libro G, Guido M, Losito L, Lamberti P, Livrea P. 2005. Habituation of single CO2 laser-evoked responses during interictal phase of migraine. J Headache Pain. 6:195-198.
42. Di Clemente L, Coppola G, Magis D, Fumal A, De Pasqua V, Di Piero V, Schoenen J. 2007. Interictal habituation deficit of the nociceptive blink reflex: an endophenotypic marker for presymptomatic migraine? Brain. 130:765-770.
43. Diedrichsen J, Balsters JH, Flavell J, Cussans E, Ramnani N. 2009. A probabilistic MR atlas of the human cerebellum. Neuroimage. 46:39-46.
44. Eichenbaum H, Lipton PA. 2008. Towards a functional organization of the medial temporal lobe memory system: role of the para-hippocampal and medial entorhinal cortical areas. Hippocampus. 18:1314-1324.
45. Eickhoff SB, Paus T, Caspers S, Grosbras MH, Evans AC, Zilles K, Amunts K. 2007. Assignment of functional activations to probabilistic cytoarchitectonic areas revisited. Neuroimage. 36:511-521.
46. Flitney D, Webster M, Patenaude B, Seidman L, Goldstein J, Tordesillas Gutierrez D, Eickhoff S, Amunts K, Zilles K, Lancaster J, et al. 2007. Anatomical brain atlases and their application in the FSLView visualisation tool. 13th Annual Meeting of the Organization for Human Brain Mapping, Chicago, IL.
47. Friston KJ. 1994. Functional and effective connectivity in neuroimaging: a synthesis. Hum Brain Mapp. 2:56-78.
48. Gear RW, Aley KO, Levine JD. 1999. Pain-induced analgesia mediated by mesolimbic reward circuits. J Neurosci. 19:7175-7181.
49. Godinho F, Magnin M, Frot M, Perchet C, Garcia-Larrea L. 2006. Emotional modulation of pain: is it the sensation or what we recall? J Neurosci. 26:11454-11461.
50. Grant AC. 2005. Interictal perceptual function in epilepsy. Epilepsy Behav. 6:511-519.
51. Granziera C, DaSilva AF, Snyder J, Tuch DS, Hadjikhani N. 2006. Anatomical alterations of the visual motion processing network in migraine with and without aura. PLoS Med. 3:e402.
52. Hall SD, Barnes GR, Hillebrand A, Furlong PL, Singh KD, Holliday IE. 2004. Spatio-temporal imaging of cortical desynchronization in migraine visual aura: a magnetoencephalography case study. Headache. 44:204-208.
53. Hamelsky SW, Lipton RB. 2006. Psychiatric comorbidity of migraine. Headache. 46:1327-1333.
54. Harle DE, Shepherd AJ, Evans BJ. 2006. Visual stimuli are common triggers of migraine and are associated with pattern glare. Headache. 46:1431-1440.
55. Hebb DO. 2002. The organization of behavior: a neuropsychological theory. Mahwah, NJ: Lawrence Erlbaum Associates, 378 p.
56. Hein G, Knight RT. 2008. Superior temporal sulcus-it's my area: or is it? J Cogn Neurosci. 20:2125-2136.
57. Iadarola MJ, Berman KF, Zeffiro TA, Byas-Smith MG, Gracely RH, Max MB, Bennett GJ. 1998. Neural activation during acute capsaicin-evoked pain and allodynia assessed with PET. Brain. 121(Pt 5): 931-947.
58. Ito M, Adachi N, Nakamura F, Koyama T, Okamura T, Kato M, Kanemoto K, Nakano T, Matsuura M, Hara S. 2003. Multi-center study on post-ictal headache in patients with localization-related epilepsy. Psychiatry Clin Neurosci. 57:385-389.
59. Jeffery KJ. 2007. Self-localization and the entorhinal-hippocampal system. Curr Opin Neurobiol. 17:684-691.
60. Katsarava Z, Giffin N, Diener HC, Kaube H. 2003. Abnormal habituation of 'nociceptive' blink reflex in migraine-evidence for increased excitability of trigeminal nociception. Cephalalgia. 23:814-819.
61. Kim J, Kim S, Suh SI, Koh SB, Park KW, Oh K. 2009. Interictal metabolic changes in episodic migraine: a voxel-based FDG-PET study. Cephalalgia. 30:53-61.
62. Kors EE, Melberg A, Vanmolkot KR, Kumlien E, Haan J, Raininko R, Flink R, Ginjaar HB, Frants RR, Ferrari MD, et al. 2004. Childhood epilepsy, familial hemiplegic migraine, cerebellar ataxia, and a new CACNA1A mutation. Neurology. 63:1136-1137.
63. Kwan P, Man CB, Leung H, Yu E, Wong KS. 2008. Headache in patients with epilepsy: a prospective incidence study. Epilepsia. 49: 1099-1102.
64. Lang E, Kaltenhauser M, Neundorfer B, Seidler S. 2004. Hyperexcitabil-ity of the primary somatosensory cortex in migraine-a magnetoencephalographic study. Brain. 127:2459-2469.
65. Lanteri-Minet M, Radat F, Chautard MH, Lucas C. 2005. Anxiety and depression associated with migraine: influence on migraine subjects' disability and quality of life, and acute migraine management. Pain. 118:319-326.
66. Lipton RB, Ottman R, Ehrenberg BL, Hauser WA. 1994. Comorbidity of migraine: the connection between migraine and epilepsy. Neurology. 44:S28-S32.
67. Lorenz J, Minoshima S, Casey KL. 2003. Keeping pain out of mind: the role of the dorsolateral prefrontal cortex in pain modulation. Brain. 126:1079-1091.
68. Lothe A, Merlet I, Demarquay G, Costes N, Ryvlin P, Mauguiere F. 2008. Interictal brain 5-HT1A receptors binding in migraine without aura: a 18F-MPPF-PET study. Cephalalgia. 28:1282-1291.
69. Maihofner C, Handwerker HO, Birklein F. 2006. Functional imaging of allodynia in complex regional pain syndrome. Neurology. 66: 711-717.
70. Melek IM, Seyfeli E, Duru M, Duman T, Akgul F, Yalcin F. 2007. Autonomic dysfunction and cardiac repolarization abnormalities in patients with migraine attacks. Med Sci Monit. 13:RA47-R49.
71. Moran MA, Mufson EJ, Mesulam MM. 1987. Neural inputs into the temporopolar cortex of the rhesus monkey. J Comp Neurol. 256:88-103.
72. Moulton EA, Becerra L, Borsook D. 2009. An fMRI case report of photophobia: activation of the trigeminal nociceptive pathway. Pain. 145:358-363.
73. Moulton EA, Burstein R, Tully S, Hargreaves R, Becerra L, Borsook D. 2008. Interictal dysfunction of a brainstem descending modulatory center in migraine patients. PLoS One. 3:e3799.
74. Moulton EA, Pendse G, Morris S, Aiello-Lammens M, Becerra L, Borsook D. 2009. Segmentally arranged somatotopy within the face representation of human primary somatosensory cortex. Hum brain mapp. 30:757-765.
75. Moulton EA, Pendse G, Morris S, Strassman A, Aiello-Lammens M, Becerra L, Borsook D. 2007. Capsaicin-induced thermal hyperalgesia and sensitization in the human trigeminal nociceptive pathway: an fMRI study. Neuroimage. 35:1586-1600.
76. Naidich TP, Duvernoy HM, Delman BN, Sorensen AG, Kollias SS, Haacke EM. 2009. Duvernoy's Atlas of the human brain stem and cerebellum. New York: Springer Wien, 876 p.
77. Obermann M, Pleger B, de Greiff A, Stude P, Kaube H, Diener HC, Katsarava Z. 2009. Temporal summation of trigeminal pain in human anterior cingulate cortex. Neuroimage. 46:193-200.
78. Olesen J. 2004. The international classification of headache disorders. 2nd ed. Cephalalgia. 24(Suppl 1):9-160.
79. Olson IR, Plotzker A, Ezzyat Y. 2007. The enigmatic temporal pole: a review of findings on social and emotional processing. Brain. 130:1718-1731.
80. Pendse G, Borsook D, Becerra L. 2009. Enhanced false discovery rate using Gaussian mixture models for thresholding fMRI statistical maps. Neuroimage. 47:231-261.
81. Peroutka SJ. 2004. Migraine: a chronic sympathetic nervous system disorder. Headache. 44:53-64.
82. Pleger B, Ragert P, Schwenkreis P, Forster AF, Wilimzig C, Dinse H, Nicolas V, Maier C, Tegenthoff M. 2006. Patterns of cortical reorganization parallel impaired tactile discrimination and pain intensity in complex regional pain syndrome. Neuroimage. 32: 503-510.
83. Ploghaus A, Narain C, Beckmann CF, Clare S, Bantick S, Wise R, Matthews PM, Rawlins JN, Tracey I. 2001. Exacerbation of pain by anxiety is associated with activity in a hippocampal network. J Neurosci. 21:9896-9903.
84. Ploghaus A, Tracey I, Clare S, Gati JS, Rawlins JN, Matthews PM. 2000. Learning about pain: the neural substrate of the prediction error for aversive events. Proc Natl Acad Sci USA. 97: 9281-9286.
85. Prescot A, Becerra L, Pendse G, Tully S, Jensen E, Hargreaves R, Renshaw P, Burstein R, Borsook D. 2009. Excitatory neuro-transmitters in brain regions in interictal migraine patients. Mol Pain. 5:34.
86. Radat F, Lanteri-Minet M, Nachit-Ouinekh F, Massiou H, Lucas C, Pradalier A, Mercier F, El Hasnaoui A. 2009. The GRIM2005 study of migraine consultation in France. III: psychological features of subjects with migraine. Cephalalgia. 29:338-350.
87. Rausell E, Bae CS, Vinuela A, Huntley GW, Jones EG. 1992. Calbindin and parvalbumin cells in monkey VPL thalamic nucleus: distribution, laminar cortical projections, and relations to spinothalamic terminations. J Neurosci. 12:4088-4111.
88. Rocca MA, Ceccarelli A, Falini A, Colombo B, Tortorella P, Bernasconi L, Comi G, Scotti G, Filippi M. 2006. Brain gray matter changes in migraine patients with T2-visible lesions: a 3-T MRI study. Stroke. 37:1765-1770.
89. Rosen SD, Paulesu E, Nihoyannopoulos P, Tousoulis D, Frackowiak RS, Frith CD, Jones T, Camici PG. 1996. Silent ischemia as a central problem: regional brain activation compared in silent and painful myocardial ischemia. Ann Intern Med. 124:939-949.
90. Rosenberg DS, Mauguiere F, Catenoix H, Faillenot I, Magnin M. 2009. Reciprocal thalamocortical connectivity of the medial pulvinar: a depth stimulation and evoked potential study in human brain. Cereb Cortex. 19:1462-1473.
91. Rosenberg DS, Mauguiere F, Demarquay G, Ryvlin P, Isnard J, Fischer C, Guenot M, Magnin M. 2006. Involvement of medial pulvinar thalamic nucleus in human temporal lobe seizures. Epilepsia. 47:98-107.
92. Sakai K. 2003. Reactivation of memory: role of medial temporal lobe and prefrontal cortex. Rev Neurosci. 14:241-252.
93. Sakai K, Passingham RE. 2003. Prefrontal interactions reflect future task operations. Nat Neurosci. 6:75-81.
94. Sandrini G, Rossi P, Milanov I, Serrao M, Cecchini AP, Nappi G. 2006. Abnormal modulatory influence of diffuse noxious inhibitory controls in migraine and chronic tension-type headache patients. Cephalalgia. 26:782-789.
95. Schmahmann JD, Doyon J, Toga AW, Petrides M, Evans AC. 2000. MRI Atlas of the human cerebellum. San Diego, CA: Academic Press, 167 p.
96. Schweinhardt P, Glynn C, Brooks J, McQuay H, Jack T, Chessell I, Bountra C, Tracey I. 2006. An fMRI study of cerebral processing of brush-evoked allodynia in neuropathic pain patients. Neuroimage. 32:256-265.
97. Seifert F, Bschorer K, De Col R, Filitz J, Peltz E, Koppert W, Maihofner C. 2009. Medial prefrontal cortex activity is predictive for hyperalgesia and pharmacological antihyperalgesia. J Neurosci. 29:6167-6175.
98. Simpson DA. 1952. The projection of the pulvinar to the temporal lobe. J Anat. 86:20-28.
99. Siqueira EB. 1965. The temporopulvinar connections in the rhesus monkey. Arch Neurol. 13:321-330.
100. Smith SM, Jenkinson M, Woolrich MW, Beckmann CF, Behrens TE, Johansen-Berg H, Bannister PR, De Luca M, Drobnjak I, Flitney DE, et al. 2004. Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage. 23(Suppl 1):S208-S219.
101. Stankewitz A, May A. 2009. The phenomenon of changes in cortical excitability in migraine is not migraine-specific-a unifying thesis. Pain. 145:14-17.
102. Strassman AM, Raymond SA, Burstein R. 1996. Sensitization of meningeal sensory neurons and the origin of headaches. Nature. 384:560-564.
103. Valeriani M, de Tommaso M, Restuccia D, Le Pera D, Guido M, Iannetti GD, Libro G, Truini A, Di Trapani G, Puca F, et al. 2003. Reduced habituation to experimental pain in migraine patients: a CO(2) laser evoked potential study. Pain. 105:57-64.
104. Valfre W, Rainero I, Bergui M, Pinessi L. 2008. Voxel-based morphom-etry reveals gray matter abnormalities in migraine. Headache. 48:109-117.
105. Vanmolkot KR, Kors EE, Hottenga JJ, Terwindt GM, Haan J, Hoefnagels WA, Black DF, Sandkuijl LA, Frants RR, Ferrari MD, et al. 2003. Novel mutations in the Na+, K+-ATPase pump gene ATP1A2 associated with familial hemiplegic migraine and benign familial infantile convulsions. Ann Neurol. 54:360-366.
106. Vincent MB, Hadjikhani N. 2007. Migraine aura and related phenomena: beyond scotomata and scintillations. Cephalalgia. 27:1368-1377.
107. Wang W, Timsit-Berthier M, Schoenen J. 1996. Intensity dependence of auditory evoked potentials is pronounced in migraine: an indication of cortical potentiation and low serotonergic neurotransmission? Neurology. 46:1404-1409.
108. Weiller C, May A, Limmroth V, Juptner M, Kaube H, Schayck RV, Coenen HH, Diener HC. 1995. Brain stem activation in spontaneous human migraine attacks. Nat Med. 1:658-660.
109. Welch KM, Nagesh V, Aurora SK, Gelman N. 2001. Periaqueductal gray matter dysfunction in migraine: cause or the burden of illness? Headache. 41:629-637.
110. Woolrich MW, Ripley BD, Brady M, Smith SM. 2001. Temporal autocorrelation in univariate linear modeling of FMRI data. Neuroimage. 14:1370-1386.
111. Yankovsky AE, Andermann F, Mercho S, Dubeau F, Bernasconi A. 2005. Preictal headache in partial epilepsy. Neurology. 65:1979-1981.
112. Yeterian EH, Pandya DN. 1989. Thalamic connections of the cortex of the superior temporal sulcus in the rhesus monkey. J Comp Neurol. 282:80-97.
113. Yeterian EH, Pandya DN. 1991. Corticothalamic connections of the superior temporal sulcus in rhesus monkeys. Exp Brain Res. 83: 268-284.
114. Zubieta JK, Smith YR, Bueller JA, Xu Y, Kilbourn MR, Jewett DM, Meyer CR, Koeppe RA, Stohler CS. 2001. Regional mu opioid receptor regulation of sensory and affective dimensions of pain. Science. 293:311-315.