Modeling basal ganglia for understanding parkinsonian reaching movements

Neural Computation

Volumn 23, Issue 2, 2011, Pages 477-516

  Magdoom, K N ^a   Subramanian, D ^a   Chakravarthy, V S ^a   Ravindran, B ^a   Amari, Shun Ichi ^b   Meenakshisundaram, N ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY MADRAS   (India)

^b RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BASAL GANGLION; BIOLOGICAL MODEL; HUMAN; LETTER; MOVEMENT (PHYSIOLOGY); PARKINSON DISEASE; PATHOPHYSIOLOGY; PHYSIOLOGY;

BASAL GANGLIA; HUMANS; MODELS, NEUROLOGICAL; MOVEMENT; PARKINSON DISEASE;

EID: 78651485805     PISSN: 08997667     EISSN: 1530888X     Source Type: Journal    
DOI: 10.1162/NECO_a_00073     Document Type: Letter

References (56)

1. Albin, R. L., Reiner, A., Anderson, K. D., Penney, J. B., & Young, A. B. (1990). Striatal and nigral neuron subpopulations in rigid Huntington's disease: implications for the functional anatomy of chorea and rigidity-akinesia. Ann. Neurol., 27, 357-365.
2. Alexander, G. E. (1987). Selective neuronal discharge in monkey putamen reflects intended direction of planned limb movements. Experimental Brain Research, 67, 623-634.
3. Berardelli, A., Noth, J., Thompson, P. D., Bollen, E. L. E. M, Curra, A., & Deuschl, G., et al. (1999). Pathophysiology of chorea and bradykinesia in Huntington's disease. Movement Disorders, 14, 398-403.
4. Berardelli, A., Rothwell, J. C., Thompson, P. D., & Hallett, M. (2001). Pathophysiology of bradykinesia in Parkinson's disease. Brain, 124, 2131-2146.
5. Bergman, H., Wichmann, T., Karmon, B., & DeLong, M. R. (1994). The primate subthalamic nucleus. II. Neuronal activity in the MPTP model of Parkinsonism. Journal of Neurophysiology, 72, 507-520.
6. Beuter, A., & Vasilakos, K. (1995). Is Parkinson's disease a dynamical disease? Chaos, 5, 35-42.
7. Bischoff, A. (1998). Modeling the basal ganglia in the control of arm movements. Unpublished doctoral dissertation, University of Southern California.
8. Brown, R. G., & Jahanshahi, M. (1996). Cognitive-motor function in Parkinson's disease. European J. Neurology., 36, 24-31.
9. Brown, P., Oliviero, A., Mazzone, P., Insola, A., Tonali, P., & Di Lazzaro, V. (2001). Dopamine dependency of oscillations between subthalamic nucleus and pallidum in Parkinson's disease. Journal of Neuroscience, 21, 1033-1038.
10. Buhusi, C. V., & Meck, W. H. (2005). What makes us tick? Functional and neural mechanisms of interval timing. Nature Reviews Neuroscience, 6, 755-756.
11. Chakravarthy, V. S., Joseph, D., & Bapi, S. R. (in press). What do the basal ganglia do? A modeling perspective. Biological Cybernetics.
12. Chaudhuri, A. & Behan, P. O. (2000). Fatigue in neurological disorders, Lancet, 179, 34-42.
13. Clark, D., Boutros, N., & Mendez, M. (2005). The brain and behavior. Cambridge: Cambridge University Press.
14. Cohen, J. D., Braver, T. S., & Brown, J. W. (2002). Computational perspectives on dopamine function in prefrontal cortex. Current Opinion in Neurobiology, 12, 223-229.
15. Cutsuridis, V., & Perantonis, S. (2006). A neural network model of Parkinson's disease bradykinesia. Neural Networks, 19, 354-374.
16. Daw, N. D., O'Doherty, J. P., Seymour, B., Dayan, P., & Dolan R. J. (2006). Cortical substrates for exploratory decisions in humans. Nature, 441, 876-879.
17. Desmurget, M., Grafton, S.T., Vindras, P., Gréa, H., & Turner, R. S. (2003). Basal ganglia network mediates the control of movement amplitude. Exp. Brain Res., 153, 197-209.
18. Dounskaia, N., Fradet, L., Lee, G., Leis, B. C., & Adler, C. H. (2009). Submovements during pointing movements in Parkinson's disease. Exp Brain Res., 193, 529-544.
19. Dreher, J. C., & Burnod, Y. (2002). An integrative theory of the phasic and tonic modes of dopamine modulation in the prefrontal cortex. Neural Networks, 15, 583-602.
20. Edwards, R., Beuter, A., & Glass, L. (1999). Parkinsonian tremor and simplification in network dynamics. Bulletin of Mathematical Biology, 61, 157-177.
21. Flowers, K. A. (1976). Visual "closed-loop" and "open-loop" characteristics of voluntary movement in patients with Parkinsonism and intention tremor. Brain, 104, 167-186.
22. Frank, M. J. (2005). Dynamic dopamine modulation in the basal ganglia: A neurocomputational account of cognitive deficits in medicated and non-medicated Parkinsonism. Journal of Cognitive Neuroscience, 17, 51-72.
23. Gangadhar, G., Joseph, D.,&Chakravarthy,V.S.(2008). Understanding Parkinsonian handwriting using a computational model of basal ganglia. Neural Computation, 20, 1-35.
24. Georgopoulos, A. P., Kalaska, J. F., & Massey, J. T. (1981). Spatial trajectories and reaction times of aimed movements: Effects of practice, uncertainty, and change in target location. J. Neurophysiology, 46, 725-743.
25. Goldberger, A. L., Rigney, D. R., & West, B. J. (1990, February). Chaos and fractals in human Physiology. Scientific American, p. 34.
26. Grace A. A. (1991). Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: A hypothesis for the etiology of schizophrenia. Neuroscience, 41, 1-24.
27. Gurney, K., Redgrave, P., & Prescott, T. J. (2001). A computational model of action selection in the basal ganglia II. Analysis and simulation of behaviour. Biological Cybernetics, 84, 411-423.
28. Hamani, C., Saint-Cyr, J. A., Fraser, J., Kaplitt, M., & Lozano, A. M. (2004). The subthalamic nucleus in the context of movement disorders. Brain, 127, 4-20.
29. Hikosaka, O., Takikawa, Y., & Kawagoe, R. (2000). Role of the basal ganglia in the control of purposive saccadic eye movements. Physiol. Rev., 80, 953-978.
30. Hurtado, J. M., Graym, C. M., Tamas, L.B., & Sigvardt, K. A. (1999). Dynamics of tremor-related oscillations in the human globus pallidus: A single case study. Neurobiology, 96, 1674-1679.
31. Isoda, M., & Hikosaka, O. (2008). Role for subthalamic nucleus neurons in switching from automatic to controlled eye movement. Journal of Neuroscience, 28, 7209-7218.
32. Joel, D., Niv, Y., & Ruppin, E. (2002). Actor-critic models of the basal ganglia: New anatomical and computational perspectives. Neural Networks, 15, 535-547.
33. Kuhl, P. K., & Meltzoff, A. N. (1996). Infant vocalizations in response to speech: Vocal imitation and developmental change. Journal of the Acoustical Society of America, 100, 2425-2438.
34. Levy, R., & Dubois, B. (2005). Apathy and the functional anatomy of the prefrontal cortex: Basal ganglia circuits. Cerebral Cortex, 16, 916-928.
35. Magnin, M., Morel, A., & Jeanmonod, D. (2000). Single-unit analysis of the pallidum, thalamus and subthalamic nucleus in Parkinsonian patients. Neuroscience, 96, 549-564.
36. May, R. M. (1976). Simple mathematical models with very complicated dynamics. Nature, 261, 459.
37. Meltzoff, A. N., & Moore, M. K. (1997). Explaining facial imitation: A theoretical model. Early Development and Parenting, 6, 179-192.
38. Montague, P. R., Dayan, P., & Sejnowski, T. J. (1996). A framework for mesencephalic dopamine systems based on predictive Hebbian learning. Journal of Neuroscience, 16, 1936-1947.
39. Nambu, A. (2008). Seven problems on the basal ganglia. Current Opinion in Neurobiology, 18, 1-10.
40. Nini, A., Feingold, A., Slovin, H., & Bergman, H. (1995). Neurons in the globus pallidus do not show correlated activity in the normal monkey, but phase-locked oscillations appear in the MPTP model of Parkinsonism. Journal of Neurophysiology, 74, 1800-1805.
41. Obeso, J.A., Rodriguez-Oroz, M. C., Blesa, F. J., & Guridi, J. (2006). The globus pallidus pars externa and Parkinson's disease. Ready for prime time? Experimental Neurology, 202, 1-7.
42. Packard, M. G., & Knowlton, B. J. (2002). Learning and memory functions of the basal ganglia. Annu. Rev. Neurosci., 25, 563-593.
43. Palop, J. J., Chin, J., & Mucke, L. (2006). A network dysfunction perspective on neurodegenerative diseases. Nature, 443, 768-773.
44. Pasupathy, A., & Miller, E. K. (2005). Different time courses of learning-related activity in the prefrontal cortex and striatum. Nature, 433, 873-876.
45. Plenz, D., & Kitai, S. T. (1999). A basal ganglia pacemaker formed by the subthalamic nucleus and external globus pallidus. Nature, 400, 677-682.
46. Redgrave, P., Prescott, T.J., & Gurney, K. (1999). The basal ganglia: A vertebrate solution to the selection problem? Neuroscience, 89, 1009-1023.
47. Schultz, W. (1998), Predictive reward signal of dopamine neurons. J. Neurophysiol. 80, 1-27.
48. Sheridan, M. R, Flowers, K. A. (1990). Movement variability and bradykinesia in Parkinson's disease. Brain, 113, 1149-1161.
49. Sridharan, D., Prashanth, P. S., & Chakravarthy, V. S. (2006). The role of the basal ganglia in exploration in a neural model based on reinforcement learning. International Journal of Neural Systems, 16, 111-124.
50. Sutton, R. S. & Barto, A.G. (1998). Reinforcement learning: An introduction. Cambridge, MA: MIT Press.
51. Terman, D., Rubin, J. E., Yew, A. C., & Wilson, C. J. (2002). Activity patterns in a model for the subthalamopallidal network of the basal ganglia. J. Neurosci., 22, 2963-2976.
52. Terry, R. D., Masliah, E., Salmon, D. P., Butters, N., DeTeresa, R., Hill, R., et al. (1991). Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment. Annals of Neurology, 30(4), 572-580.
53. Van Gemmert, A. W. A., Adler, C. H., & Stelmach, G. E. (2003). Parkinson's disease patients undershoot target size in handwriting and similar tasks. Journal of Neurology, Neurosurgery, and Psychiatry, 74, 1502-1508.
54. Walker, M. P., Ayre, G. A., Cummings, J. L., Wesnes, K., Mckeith, G., & O'Brien, J. T., et al. (2000). Quantifying fluctuation in dementia with Lewy bodies, Alzheimer's disease, and vascular dementia. Neurology, 54, 1616-1625.
55. White, O. B., Saint-Cyr, J. A., Tomlinson, R. D., & Sharpe, J. (1983). Ocular motor deficits in Parkinson's disease. II: Control of saccadic and smooth pursuit systems. Brain, 106, 571-587.
56. Yulmetyev, R. M., Demin, S. A., Panischev, O., Yu, P. H., Timashev, S. F., & Vstovsky, G.V. (2006). Regular and stochastic behavior of Parkinsonian pathological tremor signals. Physica A, 369, 655-678.