Effective recognition of HIV-1-infected cells by HIV-1 integrase-specific HLA-B*4002-restricted T cells

Microbes and Infection

Volumn 13, Issue 2, 2011, Pages 160-166

  Watanabe, Tamayo ^a,b   Murakoshi, Hayato ^a   Gatanaga, Hiroyuki ^a,b   Koyanagi, Madoka ^a   Oka, Shinichi ^a,b   Takiguchi, Masafumi ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

Author keywords

Cytotoxic T lymphocytes; HIV 1; HLA B*4002; Integrase

Indexed keywords

EPITOPE; GAG PROTEIN; HLA B ANTIGEN; INTEGRASE; NEF PROTEIN; POL PROTEIN; VPR PROTEIN;

ALLELE; ANTIGEN RECOGNITION; ARTICLE; CELL CLONE; CYTOTOXIC T LYMPHOCYTE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; PRIORITY JOURNAL; VIRUS REPLICATION;

ANTIGENS, VIRAL; CELL LINE, TRANSFORMED; EPITOPES, T-LYMPHOCYTE; HIV INFECTIONS; HIV INTEGRASE; HIV-1; HLA-B ANTIGENS; HUMANS; T-LYMPHOCYTES, CYTOTOXIC;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 78651473447     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2010.10.006     Document Type: Article

References (20)

1. Koup R.A., Safrit J.T., Cao Y., Andrews C.A., McLeod G., Borkowsky W., Farthing C., Ho D.D. Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J. Virol. 1994, 68:4650-4655.
2. + T cells with a predominant Vβ usage during the primary immune response to HIV. Nature 1994, 370:463-467.
3. Moss P.A., Rowland-Jones S.L., Frodsham P.M., McAdam S., Giangrande P., McMichael A.J., Bell J.I. Persistent high frequency of human immunodeficiency virus-specific cytotoxic T cells in peripheral blood of infected donors. Proc. Natl. Acad. Sci. U S A 1995, 92:5773-5777.
4. Rowland-Jones S., Sutton J., Ariyoshi K., Dong T., Gotch F., McAdam S., Whitby D., Sabally S., Gallimore A., Corrah T., Takiguchi M., Schultz T., McMichael A., Whittle H. HIV-1 specific cytotoxic T cells in HIV-exposed but uninfected Gambian women. Nat. Med. 1995, 1:59-64.
5. + lymphocytes can control HIV infection in vitro by suppressing virus replication. Science 1986, 234:1563-1566.
6. + cells in human immunodeficiency virus type I pathogenesis: cytolytic and noncytolytic inhibition of viral replication. Adv. Immunol. 1997, 66:273-311.
7. + T-cell cytolytic activity and cytokine production. J. Virol. 2002, 76:7535-7543.
8. Matano T., Shibata R., Siemon C., Connors M., Lane H.C., Martin M.A. Administration of an anti-CD8 monoclonal antibody interferes with the clearance of chimeric simian/human immunodeficiency virus during primary infections of rhesus macaques. J. Virol. 1998, 72:164-169.
9. Kiepiela P., Leslie A.J., Honeyborne I., Ramduth D., Thobakgale C., Chetty S., Rathnavalu P., Moore C., Pfafferott K.J., Hilton L., Zimbwa P., Moore S., Allen T., Brander C., Addo M.M., Altfeld M., James I., Mallal S., Bunce M., Barber L.D., Szinger J., Day C., Klenerman P., Mullins J., Korber B., Coovadia H.M., Walker B.D., Goulder P.J. Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA. Nature 2004, 432:769-775.
10. Itoh Y., Mizuki N., Shimada T., Azuma F., Itakura M., Kashiwase K., Kikkawa E., Kulski J.K., Satake M., Inoko H. High-throughput DNA typing of HLA-A, -B, -C, and -DRB1 loci by a PCR-SSOP-Luminex method in the Japanese population. Immunogenetics 2005, 57:717-729.
11. Altfeld M.A., Trocha A., Eldridge R.L., Rosenberg E.S., Phillips M.N., Addo M.M., Sekaly R.P., Kalams S.A., Burchett S.A., McIntosh K., Walker B.D., Goulder P.J. Identification of dominant optimal HLA-B60- and HLA-B61-restricted cytotoxic T-lymphocyte (CTL) epitopes: rapid characterization of CTL responses by enzyme-linked immunospot assay. J. Virol. 2000, 74:8541-8549.
12. Yu X.G., Shang H., Addo M.M., Eldridge R.L., Phillips M.N., Feeney M.E., Strick D., Brander C., Goulder P.J., Rosenberg E.S., Walker B.D., Altfeld M. Important contribution of p15 Gag-specific responses to the total Gag-specific CTL responses. AIDS 2002, 16:321-328.
13. Draenert R., Allen T.M., Liu Y., Wrin T., Chappey C., Verrill C.L., Sirera G., Eldridge R.L., Lahaie M.P., Ruiz L., Clotet B., Petropoulos C.J., Walker B.D., Martinez-Picado J. Constraints on HIV-1 evolution and immunodominance revealed in monozygotic adult twins infected with the same virus. J. Exp. Med. 2006, 203:529-539.
14. Altfeld M., Addo M.M., Eldridge R.L., Yu X.G., Thomas S., Khatri A., Strick D., Phillips M.N., Cohen G.B., Islam S.A., Kalams S.A., Brander C., Goulder P.J., Rosenberg E.S., Walker B.D. Vpr is preferentially targeted by CTL during HIV-1 infection. J. Immunol. 2001, 167:2743-2752.
15. Sabbaj S., Bansal A., Ritter G.D., Perkins C., Edwards B.H., Gough E., Tang J., Szinger J.J., Korber B., Wilson C.M., Kaslow R.A., Mulligan M.J., Goepfert P.A. Cross-reactive CD8+ T cell epitopes identified in US adolescent minorities. J. Acquir. Immune. Defic. Syndr. 2003, 33:426-438.
16. Bhattacharya T., Daniels M., Heckerman D., Foley B., Frahm N., Kadie C., Carlson J., Yusim K., McMahon B., Gaschen B., Mallal S., Mullins J.I., Nickle D.C., Herbeck J., Rousseau C., Learn G.H., Miura T., Brander C., Walker B., Korber B. Founder effects in the assessment of HIV polymorphisms and HLA allele associations. Science 2007, 315:1583-1586.
17. Murakoshi H., Kitano M., Akahoshi T., Kawashima Y., Dohki S., Oka S., Takiguchi M. Identification and characterization of 2 HIV-1 Gag immunodominant epitopes restricted by Asian HLA allele HLA-B*4801. Hum. Immunol. 2009, 70:170-174.
18. Borghan M.A., Oka S., Takiguchi M. Identification of HLA-A*3101-restricted cytotoxic T-lymphocyte response to human immunodeficiency virus type 1 (HIV-1) in patients with chronic HIV-1 infection. Tissue Antigens 2005, 66:305-313.
19. Akari H., Arold S., Fukumori T., Okazaki T., Strebel K., Adachi A. Nef-induced major histocompatibility complex class I down-regulation is functionally dissociated from its virion incorporation, enhancement of viral infectivity, and CD4 down-regulation. J. Virol. 2000, 74:2907-2912.
20. Falk K., Rotzschke O., Takiguchi M., Gnau V., Stevanovic S., Jung G., Rammensee H.G. Peptide motifs of HLA-B58, B60, B61, and B62 molecules. Immunogenetics 1995, 41:165-168.