Identification of phospholipid scramblase 1 as a biomarker and determination of its prognostic value for colorectal cancer

Molecular Medicine

Volumn 17, Issue 1-2, 2011, Pages 41-47

  Kuo, Yung Bin ^a   Chan, Chung Chuan ^b   Chang, C Allen ^a,c   Fan, Chung Wei ^d   Hung, Ray Ping ^e   Hung, Ya Shu ^e   Chen, Kuei Tien ^e   Yu, Jau Song ^e   Chang, Yu Sun ^e   Chan, Err Cheng ^e  

^a NATIONAL CHIAO TUNG UNIVERSITY   (Taiwan)

^b CATHAY GENERAL HOSPITAL   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

^d CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^e CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; PHOSPHOLIPID SCRAMBLASE 1; SCRAMBLASE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CANCER STAGING; COLON ADENOCARCINOMA; COLON MUCOSA; COLORECTAL CANCER; COLORECTAL CARCINOMA; CONTROLLED STUDY; DIAGNOSTIC VALUE; ENZYME ANALYSIS; ENZYME BLOOD LEVEL; FEMALE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; RECEIVER OPERATING CHARACTERISTIC; RECTUM MUCOSA; SENSITIVITY AND SPECIFICITY; SEROLOGY; TISSUE LEVEL; TISSUE SECTION;

ADENOCARCINOMA; COLORECTAL NEOPLASMS; FEMALE; HUMANS; MALE; PHOSPHOLIPID TRANSFER PROTEINS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; ROC CURVE; SENSITIVITY AND SPECIFICITY; TUMOR MARKERS, BIOLOGICAL;

EID: 78651469650     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.2119/molmed.2010.00115     Document Type: Article

References (45)

1. Parkin DM, Bray F, Ferlay J, Pisani P. (2005) Global cancer statistics, 2002. CA Cancer J. Clin. 55:74-108.
2. Kinzler KW, Vogelstein B. (1996) Lessons from hereditary colorectal cancer. Cell. 87:159-70.
3. Hardcastle JD, et al. (1996) Randomised controlled trial of faecal-occult-blood screening for colorectal cancer. Lancet. 348:1472-7.
4. Kronborg O, Fenger C, Olsen J, Jorgensen OD, Sondergaard O. (1996) Randomised study of screening for colorectal cancer with faecal-occultblood test. Lancet. 348:1467-71.
5. Walsh JM, Terdiman JP. (2003) Colorectal cancer screening: scientific review. JAMA. 289:1288-96.
6. Winawer S, et al. (2003) Colorectal cancer screening and surveillance: clinical guidelines and rationale-update based on new evidence. Gastroenterology. 124:544-60.
7. Inger DB. (1999) Colorectal cancer screening. Prim. Care. 26:179-87.
8. Ahlquist DA. (1997) Fecal occult blood testing for colorectal cancer: can we afford to do this? Gastroenterol. Clin. North Am. 26:41-55.
9. Collins JF, Lieberman DA, Durbin TE, Weiss DG. (2005) Accuracy of screening for fecal occult blood on a single stool sample obtained by digital rectal examination: a comparison with recommended sampling practice. Ann. Intern. Med. 142:81-5.
10. Duffy MJ, et al. (2007) Tumour markers in colorectal cancer: European Group on Tumour Markers (EGTM) guidelines for clinical use. Eur. J. Cancer. 43:1348-60.
11. Levy M, Visokai V, Lipska L, Topolcan O. (2008) Tumor markers in staging and prognosis of colorectal carcinoma. Neoplasma. 55:138-42.
12. Thomson DM, Krupey J, Freedman SO, Gold P. (1969) The radioimmunoassay of circulating carcinoembryonic antigen of the human digestive system. Proc. Natl. Acad. Sci. U. S. A. 64:161-7.
13. Hundt S, Haug U, Brenner H. (2007) Blood markers for early detection of colorectal cancer: a systematic review. Cancer Epidemiol. Biomarkers Prev. 16:1935-53.
14. Basse F, Stout JG, Sims PJ, Wiedmer T. (1996) Isolation of an erythrocyte membrane protein that mediates Ca2+-dependent transbilayer movement of phospholipid. J. Biol. Chem. 271:17205-10.
15. Zhao J, Zhou Q, Wiedmer T, Sims PJ. (1998) Level of expression of phospholipid scramblase regulates induced movement of phosphatidylserine to the cell surface. J. Biol. Chem. 273:6603-6.
16. Zhou Q, et al. (1997) Molecular cloning of human plasma membrane phospholipid scramblase: a protein mediating transbilayer movement of plasma membrane phospholipids. J. Biol. Chem. 272:18240-4.
17. Frasch SC, et al. (2000) Regulation of phospholipid scramblase activity during apoptosis and cell activation by protein kinase Cdelta. J. Biol. Chem. 275:23065-73.
18. Sims PJ, Wiedmer T. (2001) Unraveling the mysteries of phospholipid scrambling. Thromb. Haemost. 86:266-75.
19. Kasukabe T, Okabe-Kado J, Honma Y. (1997) TRA1, a novel mRNA highly expressed in leukemogenic mouse monocytic sublines but not in nonleukemogenic sublines. Blood. 89:2975-85.
20. Silverman RH, et al. (2002) Suppression of ovarian carcinoma cell growth in vivo by the interferon- inducible plasma membrane protein, phospholipid scramblase 1. Cancer Res. 62:397-402.
21. Chen JS, et al. (2010) Comparison of membrane fraction proteomic profiles of normal and cancerous human colorectal tissues with gel-assisted digestion and iTRAQ labeling mass spectrometry. FEBS J. 277:3028-38
22. Cattoretti G, et al. (1993) Antigen unmasking on formalin-fixed, paraffin-embedded tissue sections. J. Pathol. 171:83-98.
23. Cao WF, et al. (2007) Prognostic significance of stomatin-like protein 2 overexpression in laryngeal squamous cell carcinoma: clinical, histologic, and immunohistochemistry analyses with tissue microarray. Hum. Pathol. 38:747-52.
24. Feng Han Q, et al. (2006) Expression of sFRP-4 and beta-catenin in human colorectal carcinoma. Cancer Lett. 231:129-37.
25. Zwaal RF, Comfurius P, Bevers EM. (2005) Surface exposure of phosphatidylserine in pathological cells. Cell Mol. Life Sci. 62:971-88.
26. Huang Y, et al. (2006) Antileukemic roles of human phospholipid scramblase 1 gene, evidence from inducible PLSCR1-expressing leukemic cells. Oncogene. 25:6618-27.
27. Pastorelli C, et al. (2001) IgE receptor type I-dependent tyrosine phosphorylation of phospholipid scramblase. J. Biol. Chem. 276:20407-12.
28. Sun J, et al. (2001) c-Abl tyrosine kinase binds and phosphorylates phospholipid scramblase 1. J. Biol. Chem. 276:28984-90.
29. Dong B, et al. (2004) Phospholipid scramblase 1 potentiates the antiviral activity of interferon. J. Virol. 78:8983-93.
30. Nakamaki T, et al. (2002) Role of MmTRA1b/phospholipid scramblase1 gene expression in the induction of differentiation of human myeloid leukemia cells into granulocytes. Exp. Hematol. 30:421-9.
31. Kim H, et al. (2006) Suppression of human selenium- binding protein 1 is a late event in colorectal carcinogenesis and is associated with poor survival. Proteomics. 6:3466-76.
32. Alfonso P, et al. (2005) Proteomic expression analysis of colorectal cancer by two-dimensional differential gel electrophoresis. Proteomics. 5:2602-11.
33. Friedman DB, et al. (2004) Proteome analysis of human colon cancer by two-dimensional difference gel electrophoresis and mass spectrometry. Proteomics. 4:793-811.
34. Roessler M, et al. (2005) Identification of nicotinamide N-methyltransferase as a novel serum tumor marker for colorectal cancer. Clin. Cancer Res. 11:6550-7.
35. Stulik J, et al. (2001) Proteome study of colorectal carcinogenesis. Electrophoresis. 22:3019-25.
36. Roessler M, et al. (2006) Identification of PSME3 as a novel serum tumor marker for colorectal cancer by combining two-dimensional polyacrylamide gel electrophoresis with a strictly mass spectrometry-based approach for data analysis. Mol. Cell. Proteomics. 5:2092-101.
37. Huber K, et al. (1993) Clinical value of determination of urokinase-type plasminogen activator antigen in plasma for detection of colorectal cancer: comparison with circulating tumor-associated antigens CA 19-9 and carcinoembryonic antigen. Cancer Res. 53:1788-93.
38. Bast RC Jr, et al. (2001) 2000 update of recommendations for the use of tumor markers in breast and colorectal cancer: clinical practice guidelines of the American Society of Clinical Oncology. J. Clin. Oncol. 19:1865-78.
39. Kim HJ, Yu MH, Kim H, Byun J, Lee C. (2008) Noninvasive molecular biomarkers for the detection of colorectal cancer. BMB Rep. 41:685-92.
40. Huang Y, Zhao Q, Chen GQ. (2006) Phospholipid scramblase 1. Acta Physiol. Sin. 58:501-10.
41. Sahu SK, Gummadi SN, Manoj N, Aradhyam GK. (2007) Phospholipid scramblases: an overview. Arch. Biochem. Biophys. 462:103-14.
42. Lu B. et al. (2007) Expression of the phospholipid scramblase (PLSCR) gene family during the acute phase response. Biochim. Biophys. Acta. 1771:1177-85.
43. Mor G, et al. (2005) Serum protein markers for early detection of ovarian cancer. Proc. Natl. Acad. Sci. U.S.A. 102:7677-82.
44. Schneider J, Bitterlich N, Schulze G. (2005) Improved sensitivity in the diagnosis of gastro-intestinal tumors by fuzzy logic-based tumor marker profiles including the tumor M2-PK. Anticancer Res. 25:1507-15.
45. Yokoyama A, et al. (2004) MmTRA1b/phospholipid scramblase 1 gene expression is a new prognostic factor for acute myelogenous leukemia. Leuk. Res. 28:149-57.