A linguistic model for the rational design of antimicrobial peptides

Nature

Volumn 443, Issue 7113, 2006, Pages 867-869

  Loose, Christopher ^a   Jensen, Kyle ^a,b,c   Rigoutsos, Isidore ^a,d   Stephanopoulos, Gregory ^a  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

^c Agrivida Inc   (United States)

^d IBM T J WATSON RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; COMPUTATIONAL GRAMMARS; FORMAL LANGUAGES; IMMUNOLOGY;

AMINO ACID SEQUENCES; ANTIMICROBIAL PEPTIDES; BACTERIOSTATIC ACTIVITY;

AMINO ACIDS;

PHENYLALANYLLEUCYLGLYCYLVALYLVALYLPHENYLALANYLLYSYLLEUCYLALANYLSERYL LYSYLVALYLPHENYLALANYLPROLYLALANYLVALYLPHENYLALANYLGLYCYLLYSYLVALINE; PHENYLALANYLLEUCYLPHENYLALANYLARGINYLVALYLALANYLSERYLLYSYLVALYLPHENYL ALANYLPROLYLALANYLLEUCYLISOLEUCYLGLYCYLLYSYLPHENYLALANYLLYSYLLYSYLLYSINE; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; BACTERIAL DISEASE; EUKARYOTE; HOMOLOGY; IMMUNE SYSTEM; PEPTIDE; PROTEIN;

AMINO ACID SEQUENCE; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS ANTHRACIS; BACTERIAL INFECTION; DRUG DESIGN; DRUG DETERMINATION; DRUG IDENTIFICATION; INNATE IMMUNITY; MINIMUM INHIBITORY CONCENTRATION; MODEL; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION;

BACILLUS ANTHRACIS; BACTERIA (MICROORGANISMS); EUKARYOTA; STAPHYLOCOCCUS AUREUS;

EID: 33750304297     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature05233     Document Type: Article

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