Production of human metabolites of the anti-cancer drug flutamide via biotransformation in Cunninghamella species

Biotechnology Letters

Volumn 33, Issue 2, 2011, Pages 321-326

  Amadio, Jessica ^a   Murphy, Cormac D ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Biotransformation; Cytochrome P450; Fluorine 19 NMR; Sulfotransferase

Indexed keywords

ANTICANCER DRUG; BIOTRANSFORMATION; CYTOCHROME P450; DRUG METABOLISMS; DRUG METABOLITES; FLUORINE-19 NMR; HUMAN METABOLITES; PHASE I; PHASE II; SULFOTRANSFERASE; TRIFLUOROMETHYL;

BIOCHEMISTRY; BIOCONVERSION; BIOMOLECULES; DETOXIFICATION; FLUORINE; MAMMALS; METABOLITES;

METABOLISM;

ANILINE DERIVATIVE; ANTINEOPLASTIC AGENT; DRUG DERIVATIVE; FLUTAMIDE; HYDROXYFLUTAMIDE;

ARTICLE; BIOTRANSFORMATION; CUNNINGHAMELLA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MASS FRAGMENTOGRAPHY; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ANILINE COMPOUNDS; ANTINEOPLASTIC AGENTS; BIOTRANSFORMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CUNNINGHAMELLA; FLUTAMIDE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY;

CUNNINGHAMELLA; FUNGI; MAMMALIA;

EID: 78651414253     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-010-0425-3     Document Type: Article

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