메뉴 건너뛰기




Volumn 22, Issue 5, 2010, Pages 328-334

Enhanced bacterial uptake and bactericidal properties of ofloxacin loaded on bioadhesive hydrogels against Pseudomonas aeruginosa

Author keywords

Bacterial uptake; Bactericidal index; Bactericidal profiles; Bioahesive hydrogels; Carbomer; Fluoroquinolones

Indexed keywords

CARBOMER; CIPROFLOXACIN; GLYCINE; LEVOFLOXACIN; NORFLOXACIN; OFLOXACIN;

EID: 78651405897     PISSN: 1120009X     EISSN: 19739478     Source Type: Journal    
DOI: 10.1179/joc.2010.22.5.328     Document Type: Article
Times cited : (7)

References (29)
  • 2
    • 77953422828 scopus 로고    scopus 로고
    • Impact of antibiotic resistance in the management of ocular infections: The role of current and future antibiotics
    • Bertino JS (Jr) Impact of antibiotic resistance in the management of ocular infections: the role of current and future antibiotics. Clinical Ophthalmol 2009; 3: 507-521
    • (2009) Clinical Ophthalmol , vol.3 , pp. 507-521
    • Bertino Jr., J.S.1
  • 3
    • 0042828942 scopus 로고    scopus 로고
    • Gatifloxacin and moxifloxacin: An in vitro susceptibility comparison to levofloxacin, ciprofloxacin, and ofloxacin using bacterial keratitis isolates
    • Kowalski RP, Dhaliwal DK, Karenchak LM, Romanowski E, Mah F, Ritterband D et al. Gatifloxacin and moxifloxacin: an in vitro susceptibility comparison to levofloxacin, ciprofloxacin, and ofloxacin using bacterial keratitis isolates. Am J Ophthalmol 2003; 136: 500-505.
    • (2003) Am J Ophthalmol , vol.136 , pp. 500-505
    • Kowalski, R.P.1    Dhaliwal, D.K.2    Karenchak, L.M.3    Romanowski, E.4    Mah, F.5    Ritterband, D.6
  • 4
    • 0036206726 scopus 로고    scopus 로고
    • Fourth generation fluoroquinolones: New weapons in the arsenal of ophthalmic antibiotics
    • Mather R, Karenchak LM, Romanowski EG, Kowalski RP. Fourth generation fluoroquinolones: New weapons in the arsenal of ophthalmic antibiotics. Am J Ophthalmol 2002; 133: 463-466.
    • (2002) Am J Ophthalmol , vol.133 , pp. 463-466
    • Mather, R.1    Karenchak, L.M.2    Romanowski, E.G.3    Kowalski, R.P.4
  • 5
    • 35448958082 scopus 로고    scopus 로고
    • The increasing problem of antibiotic resistance
    • Mamalis N. The increasing problem of antibiotic resistance. J Cataract Refract Surg 2007; 33: 1831-1832
    • (2007) J Cataract Refract Surg , vol.33 , pp. 1831-1832
    • Mamalis, N.1
  • 6
    • 33646475165 scopus 로고    scopus 로고
    • Fourth-generation fluoroquinolone- Resistant bacterial keratitis after refractive surgery
    • Moshirfar M, Mirzaian G, Feiz V, Kang PC. Fourth-generation fluoroquinolone- resistant bacterial keratitis after refractive surgery. J Cataract Refract Surg 2006; 32: 515-518.
    • (2006) J Cataract Refract Surg , vol.32 , pp. 515-518
    • Moshirfar, M.1    Mirzaian, G.2    Feiz, V.3    Kang, P.C.4
  • 7
    • 85036704346 scopus 로고    scopus 로고
    • Department of Health and Human Services. USA. Access: December 2008. Available from
    • Food and Drug Administration. Department of Health and Human Services. USA. Access: December 2008. Available from: http://www.fda.gov/OHRMS/DOCKETS/ 98fr/E8-20938.htm
  • 8
    • 85036707575 scopus 로고    scopus 로고
    • Committee for Medicinal Products for Human Use (CHMP). UK. Access: august 2008. Available from
    • European Medicines Agency. Committee for Medicinal Products for Human Use (CHMP). UK. Access: august 2008. Available from: http://www.emea.europa.eu/ pdfs/human/press/pr/38292708en.pdf
  • 9
    • 42949168882 scopus 로고    scopus 로고
    • Synergy between polyethylenimine and different families of antibiotics against a resistant clinical isolate of Pseudomonas aeruginosa
    • Khalil H, Chen T, Riffon R, Wang R, Wang Z. Synergy between polyethylenimine and different families of antibiotics against a resistant clinical isolate of Pseudomonas aeruginosa. Antimicrob Agents Chemother 2008; 52: 1635-1641.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 1635-1641
    • Khalil, H.1    Chen, T.2    Riffon, R.3    Wang, R.4    Wang, Z.5
  • 10
    • 26644471255 scopus 로고    scopus 로고
    • Preface mucoadhesive polymers: Strategies, achievements and future challenges
    • Theme Editor
    • Bernkkop-Schnürch A (Theme Editor). Preface mucoadhesive polymers: strategies, achievements and future challenges. Adv Drug Deliv Rev 2005; 57:1553-1555.
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 1553-1555
    • Bernkkop-Schnürch, A.1
  • 11
    • 0002544264 scopus 로고    scopus 로고
    • Definitions, mechanisms and theories of bioadhesion
    • Mathiowitz E, Chickering III D, Lehr C-M, eds. New York: Marcel Dekker, Inc.
    • Chickering III D E, Mathiowitz E. Definitions, mechanisms and theories of bioadhesion. In: Mathiowitz E, Chickering III D, Lehr C-M, eds. Bioadhesive Drug Delivery Systems. New York: Marcel Dekker, Inc. 1999; 1-11.
    • (1999) Bioadhesive Drug Delivery Systems , pp. 1-11
    • Chickering III, D.E.1    Mathiowitz, E.2
  • 12
    • 0028810099 scopus 로고
    • An investigation into the rheological, dielectric and bioadhesive properties of poly (acrylic acid) gel systems
    • Tamburic S, Craig DQM. An investigation into the rheological, dielectric and bioadhesive properties of poly (acrylic acid) gel systems. J Controlled Rel 1995; 37: 59-68.
    • (1995) J Controlled Rel , vol.37 , pp. 59-68
    • Tamburic, S.1    Craig, D.Q.M.2
  • 13
    • 26644437438 scopus 로고    scopus 로고
    • The use of mucoadhesive polymers in ocular drug delivery
    • Ludwig A. The use of mucoadhesive polymers in ocular drug delivery. Advanced Drug Delivery Reviews 2005; 57: 1595-1639
    • (2005) Advanced Drug Delivery Reviews , vol.57 , pp. 1595-1639
    • Ludwig, A.1
  • 15
    • 0347418193 scopus 로고    scopus 로고
    • The improvement of aqueous chemical stability of a model basic drug by ion pairing with acid groups of poly electrolytes
    • Jimenez-Kairuz AF, Allemandi DA, Manzo RH. The improvement of aqueous chemical stability of a model basic drug by ion pairing with acid groups of poly electrolytes. Int J Pharm 2004; 269: 149-156
    • (2004) Int J Pharm , vol.269 , pp. 149-156
    • Jimenez-Kairuz, A.F.1    Allemandi, D.A.2    Manzo, R.H.3
  • 16
    • 58049217429 scopus 로고    scopus 로고
    • Azithromycin loaded on hydrogels of carbomer. Chemical stability and delivery properties
    • Esteban SL, Manzo RH, Alovero FL. Azithromycin loaded on hydrogels of carbomer. Chemical stability and delivery properties. Int J Pharm 2009; 366: 53-57.
    • (2009) Int J Pharm , vol.366 , pp. 53-57
    • Esteban, S.L.1    Manzo, R.H.2    Alovero, F.L.3
  • 18
    • 84869233580 scopus 로고    scopus 로고
    • Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically
    • th edition - approved standard. Wayne, PA
    • th edition - approved standard. CLSI publication M7-A7. Wayne, PA: 2006.
    • (2006) CLSI Publication M7-A7
  • 19
    • 0030748277 scopus 로고    scopus 로고
    • Bactericidal Index: A new way to assess quinolone bactericidal activity in vitro
    • Morrisey I. Bactericidal Index: a new way to assess quinolone bactericidal activity in vitro. J Antimicrob Chemother 1997; 39: 713-717
    • (1997) J Antimicrob Chemother , vol.39 , pp. 713-717
    • Morrisey, I.1
  • 20
    • 0024490880 scopus 로고
    • Fluorometric assay for fleroxacin accumulation by bacterial cells
    • Chapman JS, Georgopapadakou; NH. Fluorometric assay for fleroxacin accumulation by bacterial cells. Antimicrob Agents Chemother 1989; 33: 27-29.
    • (1989) Antimicrob Agents Chemother , vol.33 , pp. 27-29
    • Chapman, J.S.1    Georgopapadakou, N.H.2
  • 22
    • 0034119084 scopus 로고    scopus 로고
    • Bactericidal activity of gemifloxacin and other quinolones against Streptococcus pneumoniae
    • Morrisey I, George JT. Bactericidal activity of gemifloxacin and other quinolones against Streptococcus pneumoniae. J Antimicrob Chemother 2000; 45: 107-110.
    • (2000) J Antimicrob Chemother , vol.45 , pp. 107-110
    • Morrisey, I.1    George, J.T.2
  • 23
    • 0036743885 scopus 로고    scopus 로고
    • Comparative killing rates of gatifloxacin and ciprofloxacin against 14 clinical isolates: Impact of bacterial strain and antibiotic concentration
    • Pendland SL, Neuhauser MM, Garey KW, Prause JL, Jung R. Comparative killing rates of gatifloxacin and ciprofloxacin against 14 clinical isolates: impact of bacterial strain and antibiotic concentration. Diagn Microbiol Infect Dis 2002; 44: 59-61
    • (2002) Diagn Microbiol Infect Dis , vol.44 , pp. 59-61
    • Pendland, S.L.1    Neuhauser, M.M.2    Garey, K.W.3    Prause, J.L.4    Jung, R.5
  • 25
    • 0036975799 scopus 로고    scopus 로고
    • Combining molecular modelling with experimental methodologies: Mechanism of membrane permeation and accumulation of ofloxacin
    • Fresta M, Guccione S, Beccari AR, Furneri PM, Puglisi, G. Combining molecular modelling with experimental methodologies: mechanism of membrane permeation and accumulation of ofloxacin. Bioorg Med Chem 2002; 10: 3871-3889.
    • (2002) Bioorg Med Chem , vol.10 , pp. 3871-3889
    • Fresta, M.1    Guccione, S.2    Beccari, A.R.3    Furneri, P.M.4    Puglisi, G.5
  • 27
    • 0038440791 scopus 로고    scopus 로고
    • Mechanisms of resistance to quinolones: Target alterations, decreased accumulation and DNA gyrase protection
    • Ruiz J. Mechanisms of resistance to quinolones: target alterations, decreased accumulation and DNA gyrase protection. J Antimicrob Chemother 2003; 51: 1109-1117.
    • (2003) J Antimicrob Chemother , vol.51 , pp. 1109-1117
    • Ruiz, J.1
  • 28
    • 0027201571 scopus 로고
    • Accumulation and killing kinetics of fifteen quinolones for Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa
    • Asuquo A E, Piddock, LJV. Accumulation and killing kinetics of fifteen quinolones for Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa. J Antimicrob Chemother 1993; 31: 865-880.
    • (1993) J Antimicrob Chemother , vol.31 , pp. 865-880
    • Asuquo, A.E.1    Piddock, L.J.V.2
  • 29
    • 0002813177 scopus 로고    scopus 로고
    • A rheological approach to explain the mucoadhesive behavior of polymer hydrogels
    • Mathiowitz E, Chickering III D, Lehr C-M, eds. New York: Marcel Dekker, Inc.
    • Caramella CM, Rossi S, Bonferoni MC. A rheological approach to explain the mucoadhesive behavior of polymer hydrogels. In Mathiowitz E, Chickering III D, Lehr C-M, eds. Bioadhesive Drug Delivery Systems. New York: Marcel Dekker, Inc. 1999; 25-65
    • (1999) Bioadhesive Drug Delivery Systems , pp. 25-65
    • Caramella, C.M.1    Rossi, S.2    Bonferoni, M.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.