The improvement of aqueous chemical stability of a model basic drug by ion pairing with acid groups of polyelectrolytes

International Journal of Pharmaceutics

Volumn 269, Issue 1, 2004, Pages 149-156

  Jimenez Kairuz, A F ^a   Allemandi, D A ^a   Manzo, R H ^a  

^a UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

Author keywords

Carbomer hydrogels; Chemical stability improvement; Polyelectrolyte stabilizing effect; Polyelectrolyte drug interaction; Procaine stability improvement

Indexed keywords

CARBOMER; CARBOXYLIC ACID DERIVATIVE; POLYELECTROLYTE; PROCAINE;

ACIDITY; AQUEOUS SOLUTION; ARTICLE; BIOASSAY; CATALYSIS; CATALYST; CHEMICAL COMPOSITION; DRUG STABILITY; ELECTRIC POTENTIAL; FRACTIONATION; KINETICS; MICROENVIRONMENT; PH; PRIORITY JOURNAL; PROTEIN DEGRADATION;

EID: 0347418193     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2003.09.008     Document Type: Article

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