Diagnosis of focal liver lesions in cirrhotic patients: Comparison of contrast-enhanced ultrasound using sulphur hexafluoride (SF6) microbubbles and MRI using Gd-EOB-DTPA;Vergleich der kontrastverstärkten Sonografie und der MRT mit Gd-EOB-DTPA zur Diagnostik fokaler Leberläsionen bei Patienten mit Leberzirrhose

Zeitschrift fur Gastroenterologie

Volumn 49, Issue 1, 2011, Pages 23-29

  Blondin, D ^a   Erhardt, A ^a   Crynen, K ^a   Sagir, A ^a   Scherer, A ^a   Kropil P ^a   Haussinger D ^a   Modder U ^a   Kubitz, R ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

CEUS; hepatocellular carcinoma; liver; liver cirrhosis; MRI

Indexed keywords

GADOXETIC ACID; SONOVUE; SULFUR HEXAFLUORIDE;

ADULT; AGED; ALCOHOL LIVER DISEASE; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTRAST ENHANCEMENT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; ECHOGRAPHY; FEMALE; HUMAN; INTERMETHOD COMPARISON; LIVER CIRRHOSIS; LIVER INJURY; MALE; MICROBUBBLE; NUCLEAR MAGNETIC RESONANCE IMAGING; PREDICTOR VARIABLE; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; VIRUS HEPATITIS;

CONTRAST MEDIA; FEMALE; GADOLINIUM DTPA; HUMANS; IMAGE ENHANCEMENT; LIVER; LIVER CIRRHOSIS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PHOSPHOLIPIDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SULFUR HEXAFLUORIDE;

EID: 78651389675     PISSN: 00442771     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0029-1245781     Document Type: Article

References (34)

1. Jung E M., Clevert D A., Schreyer A G. et al. Evaluation of quantitative contrast harmonic imaging to assess malignancy of liver tumors: a prospective controlled two-center study. World J Gastroenterol 2007 13 (47) 6356-6364
2. Quaia E, Stacul F, Gaiani S et al. Comparison of diagnostic performance of unenhanced vs. SonoVue - enhanced ultrasonography in focal liver lesions characterization. The experience of three Italian centers. Radiol Med 2004 108 (1 - 2) 71-81
3. Stroszczynski C, Gaffke G, Gnauck M et al. Aktueller Stand der MRT-Diagnostik mit leberspezifischen Kontrastmitteln. Der Radiologe 2004 44 1185-1191
4. Tranquart F, Correas J M., Ladam Marcus V et al. Real-time contrast-enhanced ultrasound in the evaluation of focal liver lesions: diagnostic efficacy and economical issues from a French multicentric study. J Radiol 2009 90 109-122
5. Strunk H, Borner N, Stuckmann G et al. Contrast-enhanced low MI real-time sonography for the assessment of the malignancy of focal liver lesions. Fortschr Röntgenstr 2005 177 (10) 1394-1404
6. Bleuzen A, Huang C, Olar M et al. Diagnostic accuracy of contrast-enhanced ultrasound in focal lesions of the liver using cadence contrast pulse sequencing. Ultraschall in Med 2006 27 40-48
7. Dai Y, Chen M H., Yin S S. et al. Focal liver lesions: can SonoVue-enhanced ultrasound be used to differentiate malignant from benign lesions? Invest Radiol 2007 42 (8) 596-603
8. Herbay A von, Vogt C, Willers R et al. Real-time-Sonographie mit dem Ultraschallkontrastmittel SonoVue: Differenzierung zwischen benignen und malignen Leberläsionen. J Ultrasound Med 2004 23 1557-1568
9. Huppertz A, Balzer T, Blakeborough A et al. European EOB Study Group. üImproved detection of focal liver lesions at MR imaging: multicenter comparison of gadoxetic acid-enhanced MR images with intraoperative findings. Radiology 2004 230 (1) 266-275
10. Nicolau C, Catalá V, Brú C. Characterization of focal liver lesions with contrast-enhanced ultrasound. Eur Radiol 2003 13 70-78
11. Solbiati L, Tonolini M, Cova L et al. The role of contrast-enhanced ultrasound in the detection of focal liver lesions. Eur Radiol 2001 11 E15-E26
12. Dietrich C F., Kratzer W, Strobe D et al. Assessment of metastatic liver versus CT and MRI. World J Gastroenterol 2006 12 (11) 1699-1705
13. Hohmann J, Skrok J, Puls R et al. Characterization of focal liver lesions with contrast-enhanced low MI real time ultrasound and SonoVue. Fortschr Röntgentr 2003 175 (6) 835-843
14. Li R, Guo Y, Hua X et al. Characterization of focal liver lesions: comparison of pulse-inversion harmonic contrast-enhanced sonography with contrast-enhanced CT. J Clin Ultrasound 2007 35 (3) 109-117
15. Quaia E, D'Onofrio M, Palumbo A et al. Comparison of contrast-enhanced ultrasonography versus baseline ultrasound and contrast-enhanced computed tomography in metastatic disease of the liver: diagnostic performance and confidence. Eur Radiol 2006 16 (7) 1599-1609
16. Brancatelli G, Federle M P., Baron R L. et al. Arterially enhancing liver lesions: significance of sustained enhancement on hepatic venous and delayed phase with magnetic resonance imaging. J Comput Assist Tomogr 2007 31 (1) 116-124
17. Brancatelli G, Federle M P., Ambrosini R et al. Cirrhosis: CT and MR imaging evaluation. Eur J Radiol 2007 61 (1) 57-69
18. Grazioli L, Morana G, Kirchin M A. et al. Accurate differentiation of focal nodular hyperplasia from hepatic adenoma at gadobenate dimeglumine-enhanced MR imaging: prospective study. Radiology 2005 236 (1) 166-177
19. Jung G, Breuer J, Poll L W. et al. Imaging characteristics of hepatocellular carcinoma using the hepatobiliary contrast agent Gd-EOB-DTPA. Acta Radiol 2006 47 (1) 15-23
20. Karabulut N, Elmas N. Contrast agents used in MR imaging of the liver. Diagn Interv Radiol 2006 12 (1) 22-30
21. Reimer P, Schneider G, Schima W. Hepatobiliary contrast agents for contrast-enhanced MRI of the liver: properties, clinical development and applications. Eur Radiol 2004 14 559-578
22. Reimer P, Rummeny E J., Daldrup H E. et al. Enhancement characteristics of liver metastasis, hepatocallular carcinomas, and hemangiomas with Gd-EOB-DTPA: preliminary results with dynamic MR imaging. Eur Radiol 1997 7 275-280
23. Schneider G, Reimer P, Mamann A et al. Contrast agents in abdominal imaging: current and future directions. Top Magn Reson Imaging 2005 16 (1) 107-124
24. Xu H X., Liu G J., Lu M D. et al. Characterization of focal liver lesions using contrast-enhanced sonography with a low mechanical index mode and a sulfur hexafluoride-filled microbubble contrast agent. J Clin Ultrasound 2006 34 (6) 261-272
25. Halavaara J, Breuer J, Ayuso C et al. Liver tumor characterization: comparison between liver-specific gadoxetic acid disodium-enhanced MRI and biphasic CT - a multicenter trial. J Comput Assist Tomogr 2006 30 (3) 345-354
26. Strobel D, Seitz K, Blank W et al. Contrast-enhanced ultrasound for the characterization of focal liver lesions -diagnostic accuracy in clinical practice (DEGUM multicenter trial). Ultraschall in Med 2008 29 (5) 499-505
27. Roncalli M, Roz E, Coggi G et al. The vascular profile of regenerative and dysplastic nodules of the cirrhotic liver: implications for diagnosis and classification. Hepatology 1999 30 (5) 1174-1178
28. Terada T, Terasaki S, Nakanuma Y. A clinicopathologic study of adenomatous hyperplasia of the liver in 209 consecutive cirrhotic livers examined by autopsy. Cancer 1993 72 (5) 1551-1556
29. Park Y N., Kim Y B., Yang K M. et al. Increased expression of vascular endothelial growth factor and angiogenesis in the early stage of multistep hepatocarcinogenesis. Arch Pathol Lab Med 2000 124 (7) 1061-1065
30. Giorgio A, De Stefano G, Coppola C et al. Contrast-enhanced Sonography in the Characterization of small Hepatocellular Carcinomas in Cirrhotic Patients: Comparisn with Contrast-enhanced Ultrafast Magnetic Resonance Imaging. Anticancer Research 2007 27 4263-4270
31. Delorme S, Krix M, Albrecht T. Ultraschallkontrastmittel - Grundlagen und klinische Anwendung. Fortschr Röntgenstr 2006 178 155-164
32. Bleuzen A, Tranquart F. Incidental liver lesions: diagnostic value of cadence contrast pulse sequencing (CPS) and SonoVue. Eur Radiol 2004 14 (8) 53-62
33. Bolondi L, Gaiani S, Celli N et al. Characterization of small nodules in cirrhosis by assessment of vascularity: the problem of hypovascular hepatocellular carcinoma. Hepatology 2005 42 27-34
34. Petry W, Heintges T, Hensel F et al. Hepatozelluläres Karzinom in Deutschland. Epidemiologie, Etiologie, klinische Aspekte und Prognose in 100 konsekutiven Patienten einer Universitätsklinik. Z Gastroenterol 1997 35 (12) 1059-1067