Characterization of focal liver lesions using contrast-enhanced sonography with a low mechanical index mode and a sulfur hexafluoride-filled microbubble contrast agent

Journal of Clinical Ultrasound

Volumn 34, Issue 6, 2006, Pages 261-272

  Xu, Hui Xiong ^a   Liu, Guang Jian ^a   Lu, Ming De ^a   Xie, Xiao Yan ^a   Xu, Zuo Feng ^a   Zheng, Yan Ling ^a   Liang, Jin Yu ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Characterization; Cholangiocarcinoma; Contrast agent; Contrast enhanced ultrasound; Focal nodular hyperplasia; Hemangioma; Hepatocellular carcinoma; Liver metastasis; Liver neoplasm; Vascularity

Indexed keywords

CONTRAST MEDIUM; SONOVUE; SULFUR HEXAFLUORIDE;

ADULT; AGED; ARTERY BLOOD FLOW; ARTICLE; BILE DUCT CARCINOMA; CONTRAST ENHANCEMENT; CONTRAST RADIOGRAPHY; FEMALE; HEMANGIOMA; HUMAN; LIPOMA; LIVER CELL CARCINOMA; LIVER HEMANGIOMA; LIVER HYPERPLASIA; LIVER INJURY; LIVER METASTASIS; LIVER REGENERATION; MAJOR CLINICAL STUDY; MALE; PREDICTION; REAL TIME ECHOGRAPHY; SENSITIVITY AND SPECIFICITY;

ADULT; AGED; CONTRAST MEDIA; FEMALE; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; NEOVASCULARIZATION, PATHOLOGIC; PHOSPHOLIPIDS; PREDICTIVE VALUE OF TESTS; SENSITIVITY AND SPECIFICITY; SULFUR HEXAFLUORIDE;

EID: 33745758087     PISSN: 00912751     EISSN: 10970096     Source Type: Journal    
DOI: 10.1002/jcu.20234     Document Type: Article

References (26)

1. Kim TK, Choi BI, Han JK, et al. Hepatic tumors: contrast agent-enhancement patterns with pulse-inversion harmonic US. Radiology 2000;216:411.
2. Brannigan M, Burns PN, Wilson SR. Blood flow patterns in focal liver lesions at microbubble-enhanced US. Radiographics 2004;24:921.
3. Youk JH, Kim CS, Lee JM. Contrast-enhanced agent detection imaging: value in the characterization of focal hepatic lesions. J Ultrasound Med 2003; 22:897.
4. Wilson SR, Burns PN, Muradali D, et al. Harmonic hepatic US with microbubble contrast agent: initial experience showing improved characterization of hemangioma, hepatocellular carcinoma, and metastasis. Radiology 2000;215:153.
5. Giorgio A, Ferraioli G, Tarantino L, et al. Contrast-enhanced sonographic appearance of hepatocellular carcinoma in patients with cirrhosis: comparison with contrast-enhanced helical CT appearance. AJR Am J Roentgenol 2004;183:1319.
6. Quaia E, Calliada F, Bertolotto M, et al. Characterization of focal liver lesions with contrast-specific US modes and a sulfur hexafluoride-filled microbubble contrast agent: diagnostic performance and confidence. Radiology 2004;232:420.
7. Phillips P, Gardner E. Contrast-agent detection and quantification. Eur Radiol 2004;14(Suppl 8):P4.
8. Correas JM, Bridal L, Lesavre A, et al. Ultrasound contrast agents: properties, principles of action, tolerance, and artifacts. Eur Radiol 2001;11: 1316.
9. Schneider M. SonoVue, a new ultrasound contrast agent. Eur Radiol 1999;9(Suppl 3):S347.
10. Albrecht T, Blomley M, Bolondi L, et al. Guidelines for the use of contrast agents in ultrasound. January 2004. Ultraschall Med 2004;25:249.
11. Isozaki T, Numata K, Kiba T, et al. Differential diagnosis of hepatic tumors by using contrast enhancement patterns at US. Radiology 2003;229:798.
12. Nicolau C, Catala V, Bru C. Characterization of focal liver lesions with contrast-enhanced ultrasound. Eur Radiol 2003;13(Suppl 3):N70.
13. Morel DR, Schwieger I, Hohn L, et al. Human pharmacokinetics and safety evaluation of SonoVue, a new contrast agent for ultrasound imaging. Invest Radiol 2000;35:80.
14. Correas JM, Burns PN, Lai X, et al. Infusion versus bolus of an ultrasound contrast agent: in vivo dose-response measurements of BR1. Invest Radiol 2000;35:72.
15. Solbiati L, Tonolini M, Cova L. Hepatocellular carcinoma and dysplastic lesions. In: Solbiati L, Martegani A, Leen E, et al, editors. Contrast-enhanced ultrasound of liver diseases. Milan: Springer-Verlag; 2003. p 66.
16. Nicolau C, Bru C. Focal liver lesions: evaluation with contrast-enhanced ultrasonography. Abdom Imaging 2004;29:348.
17. Nicolau C, Catala V, Vilana R, et al. Evaluation of hepatocellular carcinoma using SonoVue, a second generation ultrasound contrast agent: correlation with cellular differentiation. Eur Radiol 2004;14:1092.
18. Choi BI, Lee JM, Han JK. Imaging of intrahepatic and hilar cholangiocarcinoma. Abdom Imaging 2004;29:548.
19. Lim JH. Cholangiocarcinoma: morphologic classification according to growth pattern and imaging findings. AJR Am J Roentgenol 2003;181:819.
20. Dill-Macky M, Burns P, Khalili K, et al. Focal hepatic masses: enhancement patterns with SHU 508A and pulse-inversion US. Radiology 2002;222:95.
21. Tanaka S, Ioka T, Oshikawa O, et al. Dynamic sonography of hepatic tumors. AJR Am J Roentgenol 2001;177:799.
22. Jang HJ, Choi BI, Kim TK, et al. Atypical small hemangiomas of the liver: "bright dot" sign at two-phase spiral CT. Radiology 1998;208:543.
23. Lee JY, Choi BI, Han JK, et al. Improved sonographic imaging of hepatic hemangioma with contrast-enhanced coded harmonic angiography: comparison with MR imaging. Ultrasound Med Biol 2002;28:287.
24. Ding H, Wang WP, Huang BJ, et al. Imaging of focal liver lesions: low-mechanical-index real-time ultrasonography with SonoVue. J Ultrasound Med 2005;24:285.
25. Bleuzen A, Tranquart F. Incident liver lesions: diagnostic value of cadence contrast pulse sequencing (CPS) and SonoVue. Eur Radiol 2004;14(Suppl 8):P53.
26. Ricci P, Cantisani V, Biancari F, et al. Contrast-enhanced color Doppler US in malignant portal vein thrombosis. Acta Radiol 2000;41:470.