In vitro modulatory effects of Andrographis paniculata, Centella asiatica and Orthosiphon stamineus on cytochrome P450 2C19 (CYP2C19)

Journal of Ethnopharmacology

Volumn 133, Issue 2, 2011, Pages 881-887

  Pan, Yan ^a   Abd Rashid, Badrul Amini ^b   Ismail, Zakiah ^b   Ismail, Rusli ^c   Mak, Joon Wah ^a   Pook, Peter C K ^a   Er, Hui Meng ^a   Ong, Chin Eng ^d  

^a INTERNATIONAL MEDICAL UNIVERSITY   (Malaysia)

^b INSTITUTE FOR MEDICAL RESEARCH   (Malaysia)

^c INSTITUTE FOR RESEARCH IN MOLECULAR MEDICINE INFORMM   (Malaysia)

^d MONASH UNIVERSITY MALAYSIA   (Malaysia)

Author keywords

Andrographis paniculata; Centella asiatica; CYP2C19; Drug herb interactions; Orthosiphon stamineus

Indexed keywords

ALCOHOL; ANDROGRAPHIS PANICULATA EXTRACT; CENTELLA ASIATICA EXTRACT; CYTOCHROME P450 2C19; DICHLOROMETHANE; EUPATORIN; HEXANE; MEPHENYTOIN; METHANOL; ORTHOSIPHON EXTRACT; PETROLEUM ETHER; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANDROGRAPHIS PANICULATA; ARTICLE; CENTELLA ASIATICA; DRUG ANTAGONISM; DRUG ISOLATION; DRUG SYNTHESIS; ENZYME INHIBITION; HERBAL MEDICINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; ORTHOSIPHON; SOLVENT EXTRACTION;

ANDROGRAPHIS; ARYL HYDROCARBON HYDROXYLASES; CENTELLA; ENZYME INHIBITORS; ETHNOPHARMACOLOGY; FLAVONOIDS; HERB-DRUG INTERACTIONS; HUMANS; KINETICS; ORTHOSIPHON; PLANT EXTRACTS; PLANTS, MEDICINAL; RECOMBINANT PROTEINS; TRITERPENES;

ANDROGRAPHIS PANICULATA; CENTELLA ASIATICA; ORTHOSIPHON STAMINEUS;

EID: 78651387216     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.11.026     Document Type: Article

References (28)

1. H.M. Amzad, and I. Zhari Hydroxy betulinic acid from the leaves of Orthosiphon stamineus Asian Coordinating Group for Chemistry 16 2003 69 73
2. M.V.R. Appa Rao, K. Srinivas, and T. Koteshwar Rao The effect of Mandookaparni (Centella asiatica) on the general mental ability (medhya) of mentally retarded children Indian Journal of Medical Research 8 1973 9 16
3. S. Awale, Y. Tezuka, A.H. Banskota, K. Kouda, K.M. Tun, and S. Kadota Five novel highly oxygenated diterpenes of Orthosiphon stamineus from Myanmar Journal of Natural Products 64 2001 592 596
4. P.B. Danielson The cytochrome P450 superfamily: biochemistry, evolution and drug metabolism in humans Current Drug Metabolism 3 2002 561 597
5. E.M. Gillam, Z. Guo, and F.P. Guengerich Expression of modified human cytochrome P450 2E1 in Escherichia coli, purification, and spectral and catalytic prosperities Archives of Biochemistry and Biophysics 312 1994 59 66
6. S. Gupta, M.A. Choudhry, J.N.S. Yadava, V. Srivastava, J.S. Tandon, and M. Eichelbaum Antidiarrheal activity of diterpenes of Andrographis paniculata (Kalmegh) against Escherichia coli enterotoxin in in vivo models International Journal of Crude Drug Research 28 1990 273 283
7. F.J. Gonzalez The molecular biology of cytochrome P450s Pharmacological Reviews 40 1988 243 288
8. F.P. Guengerich Cytochrome P450 and chemical toxicology Chemical Research in Toxicology 21 2008 70 83
9. G.L. Henderson, M.R. Harkey, M.E. Gershwin, R.M. Hackman, J.S. Stern, and D.M. Stresser Effects of ginseng components on cDNA-expressed cytochrome P450 enzyme catalytic activity Life Sciences 65 1999 PL209 214
10. P.C. Hollman, and M.B. Katan Dietary flavonoids: intake, health effects and bioavailability Food and Chemical Toxicology 37 1999 937 942
11. E.K. Inamdar, R.D. Yeole, A.B. Ghogare, and N.J. de Souza Determination of biologically active constituents in Centella asiatica Journal of Chromatography A 742 1996 127 130
12. K. Jarukamjorn, K. Don-in, C. Makejaruskul, T. Laha, S. Daodee, P. Pearaksa, and B.O. Sripanidkulchai Impact of Andrographis paniculata crude extract on mouse hepatic cytochrome P450 enzymes Journal of Ethnopharmacology 105 2006 464 467
13. A. Kupfer, and R. Preisig Pharmacogenetics of mephenytoin: a new drug hydroxylation polymorphism in man European Journal of Clinical Pharmacology 26 1984 753 759
14. J.M. Mathews, A.S. Etheridge, and S.R. Black Inhibition of human cytochrome P450 activities by kava extract and kavalactones Drug Metabolism and Disposition 30 2002 1153 1157
15. Y. Miyako, F. Masahiro, N. Tsuneatsu, O. Hikaru, M. Kazuhisa, T. Jiro, K. Yoshiharu, T. Ryota, K. Junei, M. Kunihide, and F. Toshihiro Antiproliferative constituents from umbelliferae plants VII. Active triterpenes and rosmarinic acid from Centella asiatica Biological & Pharmaceutical Bulletin 28 2005 173 175
16. K. Nakamura, F. Goto, W.A. Ray, C.B. McAllister, E. Jacqz, G.R. Wilkinson, and R.A. Branch Interethnic differences in genetic polymorphism of debrisoquin and mephenytoin hydroxylation between Japanese and Caucasian populations Clinical Pharmacology and Therapeutics 38 1985 402 408
17. Y. Pan, B.A. Abd-Rashid, Z. Ismail, R. Ismail, J.W. Mak, P.C. Pook, H.M. Er, and C.E. Ong In vitro modulatory effects on three major human cytochrome P450 enzymes by multiple active constituents and extracts of Centella asiatica Journal of Ethnopharmacology 130 2010 275 283
18. D. Pekthong, H. Martin, C. Abadie, A. Bonet, B. Heyd, G. Mantion, and L. Richert Differential inhibition of rat and human hepatic cytochrome P450 by Andrographis paniculata extract and andrographolide Journal of Ethnopharmacology 115 2008 432 440
19. D. Pekthong, N. Blanchard, C. Abadie, A. Bonet, B. Heyd, G. Mantion, A. Berthelot, L. Richert, and H. Martin Effects of Andrographis paniculata extract and andrographolide on hepatic cytochrome P450 mRNA expression and monooxygenase activities after in vivo administration to rats and in vitro in rat and human hepatocyte cultures Chemico-Biological Interactions 179 2009 247 255
20. A. Sharma, L. Krishan, and S.S. Handa Standardization of the Indian crude drug Kalmegh by high pressure liquid chromatographic determination of andrographolide Phytochemical Analysis 3 1992 129 131
21. Y. Tezuka, P. Stampoulis, A.H. Banskota, S. Awale, K.Q. Tran, I. Saiki, and S. Kadota Constituents of the Vietnamese medicinal plant Orthosiphon stamineus Chemical and Pharmaceutical Bulletin 48 2000 1711 1719
22. T. Usia, T. Watabe, S. Kadota, and Y. Tezuka Cytochrome P450 2D6 (CYP2D6) inhibitory constituents of Catharanthus roseus Biological and Pharmaceutical Bulletin 28 2005 1021 1024
23. L.S. Wang, G. Zhou, B. Zhu, J. Wu, J.G. Wang, A.M. Abd El-Aty, T. Li, J. Liu, T.L. Yang, D. Wang, X.Y. Zhong, and H.H. Zhou St John's wort induces both cytochrome P450 3A4-catalyzed sulfoxidation and 2C19-dependent hydroxylation of omeprazole Clinical Pharmacology and Therapeutics 75 2004 191 197
24. P.J. Wedlund, W.S. Aslanian, C.B. McAllister, G.R. Wilkinson, and R.A. Branch Mephenytoin hydroxylation deficiency in Caucasians: frequency of a new oxidative drug metabolism polymorphism Clinical Pharmacology and Therapeutics 36 1984 773 780
25. P.J. Wedlund The CYP2C19 enzyme polymorphism Pharmacology 61 2000 174 183
26. G.R. Wilkinson, F.P. Guengerich, and R.A. Branch Genetic polymorphism of S-mephenytoin hydroxylation Pharmacology and Therapeutics 43 1989 53 76
27. S.A. Wrighton, J.C. Stevens, G.W. Backer, and M. VandenBranden Isolation and characterization of human liver cytochrome P450 2C19: correlation between 2C19 and S-mephenytoin 4′-hydroxylation Archives of Biochemistry and Biophysics 306 1993 240 245
28. L. Zou, M.R. Harkey, and G.L. Henderson Effects of herbal components on cDNA-expressed cytochrome P450 enzyme catalytic activity Life Sciences 71 2002 1579 1589