Rocaglamide breaks TRAIL resistance in HTLV-1-associated adult T-cell leukemia/lymphoma by translational suppression of c-FLIP expression

Cell Death and Differentiation

Volumn 18, Issue 2, 2011, Pages 362-370

  Bleumink, M ^a   Kohler R ^a   Giaisi, M ^a   Proksch, P ^b   Krammer, P H ^a   Li Weber, M ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

anticancer drug; apoptosis; ATL; c FLIP; TRAIL

Indexed keywords

FAS LIGAND; FLICE INHIBITORY PROTEIN; HERBACEOUS AGENT; INITIATION FACTOR 4E; MITOGEN ACTIVATED PROTEIN KINASE; ROCAGLAMIDE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; HUMAN; HUMAN CELL; HUMAN T CELL LEUKEMIA VIRUS 1; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; T CELL LEUKEMIA; T CELL LYMPHOMA; TRANSLATION REGULATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BENZOFURANS; CARRIER PROTEINS; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CELL LINE, TUMOR; DOWN-REGULATION; EUKARYOTIC INITIATION FACTOR-4E; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FAS LIGAND PROTEIN; HUMAN T-LYMPHOTROPIC VIRUS 1; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEUKEMIA-LYMPHOMA, ADULT T-CELL; MAP KINASE KINASE KINASES; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

HUMAN T-LYMPHOTROPIC VIRUS 1;

EID: 78651323082     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2010.99     Document Type: Article

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