Replacement of the double bond of antitubulin chalcones with triazoles and tetrazoles: Synthesis and biological evaluation

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 2, 2011, Pages 764-768

  Mesenzani, Ornella ^a   Massarotti, Alberto ^a   Giustiniano, Mariateresa ^b   Pirali, Tracey ^a   Bevilacqua, Valentina ^a   Caldarelli, Antonio ^a   Canonico, Pierluigi ^a   Sorba, Giovanni ^a   Novellino, Ettore ^b   Genazzani, Armando A ^a   Tron, Gian Cesare ^a  

^a UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Antiproliferative activity; Chalcone; Tetrazole; Triazole; Tubulin

Indexed keywords

1 ARYL 5 AROYL TETRAZOLE; ANTINEOPLASTIC AGENT; CHALCONE DERIVATIVE; TETRAZOLE DERIVATIVE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; DRUG SYNTHESIS;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CHALCONES; HUMANS; MODELS, MOLECULAR; NEUROBLASTOMA; TETRAZOLES; TRIAZOLES; TUBULIN; TUBULIN MODULATORS;

EID: 78651243098     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.11.113     Document Type: Article

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