-
2
-
-
34547828796
-
Drug metabolism in the paediatric population and in the elderly
-
Benedetti, M.S., Whomsley, R. & Canning, M. (2007) Drug metabolism in the paediatric population and in the elderly. Drug Discovery Today, 12, 599-610.
-
(2007)
Drug Discovery Today
, vol.12
, pp. 599-610
-
-
Benedetti, M.S.1
Whomsley, R.2
Canning, M.3
-
3
-
-
0036218554
-
Changes in plasma protein binding have little clinical relevance
-
Benet, L.Z. & Hoener, B.A. (2002) Changes in plasma protein binding have little clinical relevance. Clinical Pharmacology and Therapeutics, 71, 115-121.
-
(2002)
Clinical Pharmacology and Therapeutics
, vol.71
, pp. 115-121
-
-
Benet, L.Z.1
Hoener, B.A.2
-
4
-
-
78651251794
-
-
A comparison of methods for handling of data below the limit of quantification in NONMEM., Abstr. 1201, Available at: Accessed 19 March 2010
-
Bergstrand, M., Plan, E., Kjellsson, M. & Karlsson, M. (2007) A comparison of methods for handling of data below the limit of quantification in NONMEM. Abstr. 1201, p. 16. Available at: Accessed 19 March 2010.
-
(2007)
, pp. 16
-
-
Bergstrand, M.1
Plan, E.2
Kjellsson, M.3
Karlsson, M.4
-
5
-
-
84919953597
-
Pharmacokinetic-Pharmacodynamic Modeling and Simulation
-
Springer Science+Business Median, Inc., New York.
-
Bonate, P. (2006) Pharmacokinetic-Pharmacodynamic Modeling and Simulation. Springer Science+Business Median, Inc., New York.
-
(2006)
-
-
Bonate, P.1
-
6
-
-
77956624392
-
The pharmacokinetics of mavacoxib, a long-acting Cox-2 inhibitor, in young adult laboratory Beagles
-
DOI: 10.1111/j.1365-2885.2010.01165.x.
-
Cox, S.R., Lesman, S.P., Boucher, J.F., Krautmann, M.J., Hummel, B.D., Michels, G., Marsh, S., Fielder, A. & Stegemann, M.R. (2010) The pharmacokinetics of mavacoxib, a long-acting Cox-2 inhibitor, in young adult laboratory Beagles. Journal of Veterinary Pharmacology and Therapeutics; DOI: 10.1111/j.1365-2885.2010.01165.x.
-
(2010)
Journal of Veterinary Pharmacology and Therapeutics
-
-
Cox, S.R.1
Lesman, S.P.2
Boucher, J.F.3
Krautmann, M.J.4
Hummel, B.D.5
Michels, G.6
Marsh, S.7
Fielder, A.8
Stegemann, M.R.9
-
8
-
-
78651242796
-
-
EMEA European Medicines Agency, Trocoxil - European Public Assessment Report. Available at: Accessed 19 March 2010.
-
EMEA (2008) European Medicines Agency, Trocoxil - European Public Assessment Report. Available at: Accessed 19 March 2010.
-
(2008)
-
-
-
9
-
-
78651244811
-
-
Manuscript in preparation.
-
Hummel, B.D., Locuson, C.W., Benner, C.P., Zaya, M.J., Cox, T.D., Cox, S.R. & Stegemann, M.R. (2010) Manuscript in preparation.
-
(2010)
-
-
Hummel, B.D.1
Locuson, C.W.2
Benner, C.P.3
Zaya, M.J.4
Cox, T.D.5
Cox, S.R.6
Stegemann, M.R.7
-
10
-
-
84889420924
-
Pharmacometrics: The Science of Quantitative Pharmacology
-
Eds, Ette, E. &, Williams, P. John Wiley and Sons, Hoboken, NJ.
-
Jonsson, E., Karlsson, M. & Milligan, P. (2007) Graphical displays for modeling population data. In Pharmacometrics: The Science of Quantitative Pharmacology. Eds Ette, E. & Williams, P., pp. 183-222. John Wiley and Sons, Hoboken, NJ.
-
(2007)
Graphical displays for modeling population data
, pp. 183-222
-
-
Jonsson, E.1
Karlsson, M.2
Milligan, P.3
-
12
-
-
68149091172
-
Target animal safety studies of mavacoxib in dogs. 11th International Congress of the European Association for Veterinary Pharmacology and Toxicology, Leipzig, Germany
-
Krautmann, M.J., Boucher, J.F., Cox, S.R., Savides, M.C. & Stegemann, M.R. (2009) Target animal safety studies of mavacoxib in dogs. 11th International Congress of the European Association for Veterinary Pharmacology and Toxicology, Leipzig, Germany, Journal of Veterinary Pharmacology and Therapeutics, 32(Suppl. 1), 104-105.
-
(2009)
Journal of Veterinary Pharmacology and Therapeutics
, vol.32
, Issue.SUPPL. 1
, pp. 104-105
-
-
Krautmann, M.J.1
Boucher, J.F.2
Cox, S.R.3
Savides, M.C.4
Stegemann, M.R.5
-
13
-
-
68149142254
-
Pharmacokinetics and pharmacodynamics of mavacoxib in the dog. 11th International Congress of the European Association for Veterinary Pharmacology and Toxicology, Leipzig, Germany, 12-16 July
-
Lees, P., Alexander-Bowman, S., Hummel, B., Kubiak, T., Michels, G., Krautmann, M., Cox, S., Toutain, P. & Stegemann, M. (2009) Pharmacokinetics and pharmacodynamics of mavacoxib in the dog. 11th International Congress of the European Association for Veterinary Pharmacology and Toxicology, Leipzig, Germany, 12-16 July. Journal of Veterinary Pharmacology and Therapeutics, 32(Suppl. 1), 105-106.
-
(2009)
Journal of Veterinary Pharmacology and Therapeutics
, vol.32
, Issue.SUPPL. 1
, pp. 105-106
-
-
Lees, P.1
Alexander-Bowman, S.2
Hummel, B.3
Kubiak, T.4
Michels, G.5
Krautmann, M.6
Cox, S.7
Toutain, P.8
Stegemann, M.9
-
14
-
-
61449142646
-
Regulation of drug transporter expression in human hepatocytes exposed to the proinflammatory cytokines tumor necrosis factor-alpha or interleukin-6
-
Lee Vee, M., Lecureur, V., Stieger, B. & Fardel, O. (2009) Regulation of drug transporter expression in human hepatocytes exposed to the proinflammatory cytokines tumor necrosis factor-alpha or interleukin-6. Drug Metabolism and Disposition, 37, 685-693.
-
(2009)
Drug Metabolism and Disposition
, vol.37
, pp. 685-693
-
-
Lee Vee, M.1
Lecureur, V.2
Stieger, B.3
Fardel, O.4
-
15
-
-
34548257223
-
The impact of advancing age on P-glycoprotein expression and activity: current knowledge and future directions
-
Mangoni, A.A. (2007) The impact of advancing age on P-glycoprotein expression and activity: current knowledge and future directions. Expert Opinion on Drug Metabolism & Toxicology, 3, 315-320.
-
(2007)
Expert Opinion on Drug Metabolism & Toxicology
, vol.3
, pp. 315-320
-
-
Mangoni, A.A.1
-
16
-
-
0033120135
-
A procedure for generating bootstrap samples for the validation of nonlinear mixed-effects population models
-
Parke, J., Holford, N.H. & Charles, B.G. (1999) A procedure for generating bootstrap samples for the validation of nonlinear mixed-effects population models. Computer Methods and Programs in Biomedicine, 59, 19-29.
-
(1999)
Computer Methods and Programs in Biomedicine
, vol.59
, pp. 19-29
-
-
Parke, J.1
Holford, N.H.2
Charles, B.G.3
-
17
-
-
68149136190
-
Efficacy and safety of mavacoxib in the treatment of pain and inflammation associated with degenerative joint disease in dogs presented as veterinary patients. 11th Interational Congress of the European Association for Veterinary Pharmacology and Toxicology, Leipzig, Germany, 12-16 July
-
Payne-Johnson, M., Boucher, J.F. & Stegemann, M.R. (2009) Efficacy and safety of mavacoxib in the treatment of pain and inflammation associated with degenerative joint disease in dogs presented as veterinary patients. 11th Interational Congress of the European Association for Veterinary Pharmacology and Toxicology, Leipzig, Germany, 12-16 July. Journal of Veterinary Pharmacology and Therapeutics, 32(Suppl. 1), 106-107.
-
(2009)
Journal of Veterinary Pharmacology and Therapeutics
, vol.32
, Issue.SUPPL. 1
, pp. 106-107
-
-
Payne-Johnson, M.1
Boucher, J.F.2
Stegemann, M.R.3
-
18
-
-
33747114409
-
Regulation of drug metabolism and disposition during inflammation and infection
-
Renton, K.W. (2005) Regulation of drug metabolism and disposition during inflammation and infection. Expert Opinion on Drug Metabolism & Toxicology, 1, 629-640.
-
(2005)
Expert Opinion on Drug Metabolism & Toxicology
, vol.1
, pp. 629-640
-
-
Renton, K.W.1
-
19
-
-
78651240343
-
-
VICH International Co-operation on Harmonisation of Technical Requirements for Registration of Veterinary Medicinal Products, Good Clinical Practice, June 2000 effective 1 July, VICH, Bruxelles, Belgium. Available at Accessed 19 March 2007.
-
VICH (2000) International Co-operation on Harmonisation of Technical Requirements for Registration of Veterinary Medicinal Products, Good Clinical Practice, June 2000 effective 1 July, VICH, Bruxelles, Belgium. Available at Accessed 19 March 2007.
-
(2000)
-
-
-
20
-
-
33947611171
-
The effect of ageing on cytochrome p450 enzymes: consequences for drug biotransformation in the elderly
-
Wauthier, V., Verbeeck, R.K. & Calderon, P.B. (2007) The effect of ageing on cytochrome p450 enzymes: consequences for drug biotransformation in the elderly. Current Medicinal Chemistry, 14, 745-757.
-
(2007)
Current Medicinal Chemistry
, vol.14
, pp. 745-757
-
-
Wauthier, V.1
Verbeeck, R.K.2
Calderon, P.B.3
|