Advance in the study of poly(lactide-co-glycolide) nano/microparticles as gene vector

Yaoxue Xuebao

Volumn 45, Issue 11, 2010, Pages 1346-1353

  Zeng, Ping ^a   Peng, Ming Li ^b   Xu, Yi ^a  

^a CHONGQING UNIVERSITY   (China)

^b CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Gene delivery system; Gene therapy; Poly(lactide co glycolide); Surface modification

Indexed keywords

NANOPARTICLE; PLASMID DNA; POLYGLACTIN; VACCINE;

BIODEGRADABILITY; GENE DELIVERY SYSTEM; GENE THERAPY; GENE VECTOR; IMMUNOGENICITY; NONVIRAL GENE DELIVERY SYSTEM; REVIEW; SAFETY;

DRUG CARRIERS; DRUG DELIVERY SYSTEMS; EMULSIONS; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; LACTIC ACID; MICROSPHERES; NANOPARTICLES; PARTICLE SIZE; PLASMIDS; POLYGLYCOLIC ACID; POLYMERS;

EID: 78651237684     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (48)

1. Gary DJ, Puri N, Won YY. Polymer-based siRNA delivery: perspectives on the fundamental and phenomenological distinctions from polymer-based DNA delivery [J]. J Control Release, 2007, 121: 64-73. (Pubitemid 47126065)
2. Lee YK, So IS, Lee SC, et al. Suppression of distant pulmonary metastasis of MDA2-MB 435 human breast carcinoma established in mammary fat pads of nude mice by retroviral-mediated TMP-2 gene transfer [J]. J Gene Med, 2005, 7: 145-157.
3. Kenneth R, Rogulshki MS, Wing DL, et al. Double suicide gene therapy augments the antitumor activity of a replication-competent lytic adenovirus through enhanced cytotoxicity and radiosensitization [J]. Hum Gene Ther, 2000, 1: 67-76.
4. Wang Z, Zhu T, Qiao C, et al. Adeno-associated virus serotype 8 efficiently delivers genes to muscle and heart [J]. Nat Biotechnol, 2005, 23: 321-328. (Pubitemid 41094420)
5. Zimmermann TS, Lee AC, Akinc A, et al. RNAi-mediated gene silencing in non-human primates [J]. Nature, 2006, 441: 111-114.
6. Herweijer H, Wolff JA. Progress and prospects: naked DNA genetransfer and therapy [J]. Gene Ther, 2003, 10: 453-458.
7. Mundargi RC, Babu VR, Rangaswamy V, et al. Nano/micro technologies for delivering macromolecular therapeutics using poly(D,L-lactide-co-glycolide) and its derivatives [J]. J Control Release, 2008, 125: 193-209.
8. Panyam J, Labhasetwar V. Biodegradable nanoparticles for drug and gene delivery to cells and tissue [J]. Adv Drug Deliv Rev, 2003, 55: 329-347.
9. Prabha S, Labhasetwar V. Critical determinants in PLGA/PLA nanoparticle-mediated gene expression [J]. Pharm Res, 2004, 21: 354-364.
10. Luten J, van Nostrum CF, De Smedt SC, et al. Biodegradable polymers as non-viral carriers for plasmid DNA delivery [J]. J Control Release, 2008, 126: 97-110.
11. Bala I, Hariharan S, Kumar M, et al. PLGA nanoparticles in drug delivery: the state of the art [J]. Crit Rev Ther Drug Carrier Syst, 2004, 21: 387-422.
12. Jilek S, Merkle HP, Walter E. DNA-loaded biodegradablemicroparticles as vaccine delivery systems and their interaction with dendritic cells [J]. Adv Drug Deliv Rev, 2005, 57: 377-390.
13. Singh M, Briones M, Ott G, et al. Cationic microparticles: a potent delivery system for DNA vaccines [J]. Proc Natl Acad Sci USA, 2000, 97: 811-816.
14. Jeremy S, Blum, W, Saltzman M. High loading efficiency and tunable release of plasmid DNA encapsulated in submicron particles fabricated from PLGA conjugated with poly-L-lysine [J]. J Control Release, 2008, 129: 66-72.
15. Tahara K, Sakai T, Yamamoto H, et al. Establishing chitosan coated PLGA nanosphere platform loaded with wide variety of nucleic acid by complexation with cationic compound for gene delivery [J]. Int J Pharm, 2008, 354: 210-216.
16. Katas H, Cevher E, Alpar HO. Preparation of polyethyleneimineincorporatedpoly(D,L-lactide-co-glycolide) nanoparticles by spontaneous emulsion diffusion method for small interfering RNA delivery [J]. Int J Pharm, 2009, 369: 144-154.
17. Zhuang FF, Liang R, Zou CT, et al. High efficient encapsulation of plasmid DNA in PLGA microparticles by organic phase selfe-mulsification [J]. J Biochem Biophys Methods, 2002, 52: 169-178.
18. Takashima Y, Saito R, Nakajima A, et al. Spray-drying preparation of microparticles containing cationic PLGA nanospheres as gene carriers for avoiding aggregation of nanospheres [J]. Int J Pharm, 2007, 343: 262-269.
19. Mayo AS, Ambati BK, Kompella UB. Gene delivery nanoparticles fabricated by supercritical fluid extraction of emulsions [J]. Int J Pharm, 2010, 387: 278-285.
20. Zhang XQ, Dahle CE, Baman NK, et al. Potent antigen-specific immune responses stimulated by co-delivery of CpG ODN and antigens in degradable microparticles [J]. J Immunother, 2007, 30: 469-478.
21. Walter E, Moelling K, Pavlovic J, et al. Microencapsulation of DNA using poly/(D, L-lactic-co-glycolide) stability issues and release characteristics [J]. J Control Release, 1999, 61: 361-374.
22. Lane ME, Brennan FS, Corrigan OI. Comparison of post-emulsification freeze drying or spray drying processes for the microencapsulation of plasmid DNA [J]. J Pharm Pharmacol, 2005, 57: 831-838.
23. Maczurek A, Hager K, Kenklies M, et al. Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer's disease [J]. Adv Drug Deliv Rev, 2008, 60: 1463-1470.
24. Nie H, Lee LY, Tong H, et al. PLGA/chitosan composites from a combination of spray drying and supercritical fluid foaming techniques: new carriers for DNA delivery [J]. J Control Release, 2008, 129: 207-214.
25. Singh M, Ugozzoli M, Briones M, et al. The effect of CTAB concentration in cationic PLGA microparticles on DNA adsorption and in vivo performance [J]. Pharm Res, 2003, 20: 247-251. (Pubitemid 36269731)
26. Fischer S, Foerg C, Merkle HP, et al. One-step preparation of polyelectrolyte-coated PLGA microparticles and their functionalization with model ligands [J]. J Control Release, 2006, 111: 135-144. (Pubitemid 43290002)
27. Kasturi SP, Sachaphibulkij K, Roy K. Covalent conjugation of polyethyleneimine on biodegradable microparticles for delivery of plasmid DNA vaccines [J]. Biomaterials, 2005, 26: 6375-6385. (Pubitemid 40828393)
28. Andersen M, Lichawska A, Arpanaei A, et al. Surface functionalisation of PLGA nanoparticles for gene silencing [J]. Biomaterials, 2010, 31: 5671-5677.
29. Green JJ, Langer R, Anderson DG. A combinatorial polymer library approach yields insight into nonviral gene delivery [J]. Acc Chem Res, 2008, 41: 749-759.
30. Mok H, Park JW, Park TG. Microencapsulation of PEGylated adenovirus within PLGA microspheres for enhanced stability and gene transfection efficiency [J]. Pharm Res, 2007, 24: 2263-2269. (Pubitemid 350060718)
31. Csaba N, Sánchez A, Alonso MJ. PLGA:poloxamer and PLGA: poloxamine blend nanostructures as carriers for nasal gene delivery [J]. J Control Release, 2006, 113: 164-172. (Pubitemid 43928142)
32. Sun X, Duan YR, He Q, et al. PELGE nanoparticles as new carriers for the delivery of plasmid DNA [J]. Chem Pharm Bull, 2005, 53: 599-603. (Pubitemid 40880246)
33. Moffatt S, Cristiano RJ. PEGylated J591 mAb loaded in PLGA-PEG-PLGA tri-block copolymer for targeted delivery: in vitro evaluation in human prostate cancer cells [J]. Int J Pharm, 2006, 317: 10-13. (Pubitemid 43866350)
34. Moffatt S, Choi D, Kim WJ, et al. Non-ionic amphiphilic biodegradable PEG-PLGA-PEG copolymer enhances gene delivery efficiency in rat skeletal muscle [J]. J Control Release, 2007, 118: 245-253. (Pubitemid 46331900)
35. Garinot M, Fiévez V, Pourcelle V, et al. PEGylated PLGA-based nanoparticles targeting M cells for oral vaccination [J]. J Control Release, 2007, 120: 195-204.
36. Diez S, Navarro G, de ILarduya CT. In vivo targeted gene delivery by cationic nanoparticles for treatment of hepatocellular carcinoma [J]. J Gene Med, 2009, 11: 38-45.
37. Bivas-Benita M, Romeijn S, Junginger HE, et al. PLGA-PEI nanoparticles for gene delivery to pulmonary epithelium [J]. Eur J Pharm Biopharm, 2004, 58: 1-6. (Pubitemid 38780998)
38. Zou W, Liu C, Chen Z, et al. Studies on bioadhesive PLGA nanoparticles: a promising gene delivery system for efficient gene therapy to lung cancer [J]. Int J Pharm, 2009, 370: 187-195.
39. Pickel L, Matsuzuka T, Doi C, et al. Overexpression of angiotensin II type 2 receptor gene induces cell death in lung adenocarcinoma cells [J]. Cancer Biol Ther, 2010, 9: 277-285.
40. Mayo AS, Ambati BK, Kompella UB. Gene delivery nanoparticles fabricated by supercritical fluid extraction of emulsions [J]. Int J Pharm, 2010, 387: 278-285.
41. Braden AR, Kafka MT, Cunningham L, et al. Polymeric nanoparticles for sustained down-regulation of annexin A2 inhibit prostate tumor growth [J]. J Nanosci Nanotechnol, 2009, 9: 2856-2865.
42. Csaba N, Sánchez A, Alonso MJ. PLGA: poloxamer and PLGA: poloxamine blend nanostructures as carriers for nasal gene delivery [J]. J Control Release, 2006, 113: 164-172. (Pubitemid 43928142)
43. Eratalay A, Coşkun-Ari FF, Oner F, et al. In vitro and in vivo evaluations of PLGA microsphere vaccine formulations containing pDNA coexpressing hepatitis B surface antigen and interleukin-2 [J]. J Microencapsul, 2010, 27: 48-56.
44. Kanazawa T, Takashima Y, Murakoshi M, et al. Enhancement of gene transfection into human dendritic cells using cationic PLGA nanospheres with a synthesized nuclear localization signal [J]. Int J Pharm, 2009, 379: 187-195.
45. Liu S, Danquah MK, Forde GM, et al. Microparticle-mediated gene delivery for the enhanced expression of a 19-kDa fragment of merozoite surface protein of Plasmodium falciparum [J]. Biotechnol Prog, 2009, 26: 257-262.
46. Kasturi SP, Qin H, Thomson KS, et al. Prophy-lactic anti-tumor effects in a B cell lymphoma model with DNA vaccines delivered on polyethylenimine (PEI) functionalized PLGA microparticles [J]. J Control Release, 2006, 113: 261-270. (Pubitemid 43977789)
47. Bivas-Benita M, Lin MY, Bal SM, et al. Pulmonary delivery of DNA encoding Mycobacterium tuberculosis latency antigen Rv1733c associated to PLGA-PEI nanoparticles enhances T cell responses in a DNA prime/protein boost vaccination regimen in mice [J]. Vaccine, 2009, 27: 4010-4017.
48. Zhou X, Liu B, Yu X, et al. Controlled release of PEI/DNA complexes from PLGA microspheres as a potent delivery system to enhance immune response to HIV vaccine DNA prime/MVA boost regime [J]. Eur J Pharm Biopharm, 2008, 68: 589-595.