Impacts of bicyclo-monoterpene enhancers on transdermal delivery of ligustrazine

Yaoxue Xuebao

Volumn 45, Issue 11, 2010, Pages 1452-1458

  Zhang, Chun Feng ^a   Zhan, Wei ^b   Yang, Zhong Lin ^a   Wang, Ye Li ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b Qingdao Growful Medicine Co Ltd   (China)

Author keywords

Bicyclo monoterpene enhancer; Ligustrazine; Percutaneous absorption; Permeation mechanism

Indexed keywords

BICYCLO COMPOUND; BORNEOL; CAMPHOR; KETONE; PENETRATION ENHANCING AGENT; TERPENE; TETRAMETHYLPYRAZINE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DESQUAMATION; DRUG PENETRATION; HYDROGEN BOND; IN VITRO STUDY; INFRARED SPECTROSCOPY; NONHUMAN; SCANNING ELECTRON MICROSCOPY; SKIN ABSORPTION; STRATUM CORNEUM; SWINE; TRANSDERMAL DRUG ADMINISTRATION;

ADMINISTRATION, CUTANEOUS; ANIMALS; BORNANES; CAMPHOR; DRUG CARRIERS; LIGUSTICUM; MICROSCOPY, ELECTRON, SCANNING; MONOTERPENES; PLANTS, MEDICINAL; PYRAZINES; SKIN; SKIN ABSORPTION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SWINE; VASODILATOR AGENTS;

EID: 78651237683     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Li P. Pharmacokinetic study and clinical application of ligustrazine hydrochloride [J]. Mod J Integr Tradit Chin West Med, 2005, 14: 1622-1623.
2. Xu R, Li Y, Huang X. Pharmacokinetic developments in ligustrazine [J]. J Anhui Tradit Chin Med Coll, 2002, 21: 58-61.
3. Chen Y, Liu M. Systematic evaluation of security of ligustrazine for treatment of cerebral infarction [J]. Chin J Clin Rehabil, 2004, 8: 1299-1301. (Pubitemid 38637311)
4. Guy RH. Current status and future prospects of transdermal drug delivery [J]. Pharm Res, 1996, 13: 765-1769.
5. Pilgram GS, Van Pelt AM, Spies F, et al. Cryo-electron diffraction as a tool to study local variations in the lipid organization of human stratum corneum [J]. J Microsc, 1998, 189: 71-78. (Pubitemid 28096327)
6. Sweeny TM, Downing DT. The role of the lipids in the epidermal barrier to water diffusion [J]. J Invest Dermato, 1970, 55: 135-140.
7. Moghimi HR, Williams AC, Barrry BW. A lamellar matrix model for stratum corneum intercellular lipids. II. Effect of geometry of the stratum corneum on permeation of model drugs 5-fluorouracil and oestradiol [J]. Int J Pharm, 1996, 131: 117-129.
8. Boddé HE, van den Brink I, Koerte HK, et al. Visualization of in vitro percutaneous penetration of mercuric chloride transport through intercellular space versus cellular uptake through desmosomes [J]. J Control Release, 1991, 15: 227-236.
9. Akithoshi Y, Takayama K, Machida Y, et al. Effect of cycohexanone derivatives on percutaneous absorption of ketoprofen and indomethacin [J]. Drug Design Deliv, 1988, 3: 239-345.
10. Moghimi HR, Williams AC, Barry BW. A lamellar matrix model for stratum corneum intercellular lipids IV. Effects of terpene penetration enhancers on the permeation of 5-fluorouracil and oestradiol through the matrix [J]. Int J Pharm, 1996, 145: 49-59.
11. Williams AC, Barry BW. Terpenes and the lipid-protein-partitioning theory of skin penetration enhancement [J]. Pharm Res, 1991, 8: 17-24.
12. Zhao K, Singh J. In vitro percutaneous absorption enhancement of propranolol hydrochloride through porcine epidermis by terpene/ethanol [J]. J Control Release, 1999, 62: 359-366.
13. Xiao YY, Chen ZP, Ping QN, et al. The enhancing effect of borneol on the absorption of tetramethylpyrazine [J]. Acta Pharm Sin, 2009, 44: 915-921.
14. Zhang CF, Yang ZL, Luo JB. Effects of enantiomer and isomer permeation enhancers on transdermal delivery of ligustrazine hydrochloride [J]. Pharm Dev Tech, 2006, 11: 417-424.
15. Zhang CF, Yang ZL, Luo JB. Effects of D-limonene and L-limonene on transdermal absorption of ligustrazine hydrochloride [J]. Acta Pharm Sin, 2006, 41: 772-777.
16. Zhang CF, Yang ZL, Luo JB, et al. Effects of cinnamene enhancers on transdermal delivery of ligustrazine hydrochloride [J]. Eur J Pharm Biopharm, 2007, 67: 413-419.
17. Monteiro-Riviere NA. Ultrastructural evaluation of porcine integument. Tumbleson ME (Ed.), Swine in Biomedical Research [M]. New York: Plenum Press, 1986: 641-655.
18. Gray GM, Yardley HJ. Lipid composition cells isolated from pig, human and rat epidermis [J]. J Lipid Res, 1975, 16: 434-440.
19. Montagna W, Yun JS. The skin of domestic pig [J]. J Invest Dermatol, 1964, 42: 11-21.
20. Zhao K, Singh J. Mechanisms of percutaneous absorption of tamoxifen by terpenes: eugenol, D-limonene and menthone [J]. J Control Release, 1998, 55: 253-260. (Pubitemid 28477616)
21. Potts RO, Francoeur ML. Infrared spectroscopy of stratum corneum lipids: in vitro results and their relevance to permeability. Walters KA, Hadgraft J (Eds.), Pharmaceutical Skin Permeation Enhancement [M]. New York: Marcel Dekker, 1993: 269-291.
22. Casal HL, Mantsch HH. Polymorphic phase behaviour of phosphlipid membranes studied by infrared spectroscopy [J]. Biochim Biophys Acta, 1984, 779: 381-401.
23. Bhatia KS, Singh J. Mechanism of transport enhancement of LHRH through porcine epidermis by terpenes and iontophoresis: permeability and lipid extraction studies [J]. Pharm Res, 1998, 15: 1857-1862. (Pubitemid 29034834)
24. Takahashi K, Sakano H, Yoshida M, et al. Characterization of the influence of polyol fatty acid esters on the permeation of diclofenac through rat skin [J]. J Control Release, 2001, 73: 351-358. (Pubitemid 32539262)
25. Yokomizo Y, Sagitani H. Effects of phospholipids on the in vitro percutaneous penetration of prednisolone and analysis of mechanism by using attenuated total reflectance-Fourier transform infrared spectroscopy [J]. J Pharm Sci, 1996, 85: 1220-1226.
26. Vaddi HK, Ho PC, Chan YW, et al. Oxide terpenes as human skin penetration enhancers of haloperidol from ethanol and propylene glycol and their modes of action on stratum corneum [J]. Biol Pharm Bull, 2003, 26: 220-228.
27. Scheuplein RJ, Blank IH. Permeability of the skin [J]. Physiol Rev, 1971, 51: 702-747.
28. Arellano A, Santoyo S, Martin C, et al. Enhancing effect of terpenes on the in vitro percutaneous absorption of diclofenac sodium [J]. Int J Pharm, 1996, 130: 141-145. (Pubitemid 26129793)
29. Jain AK, Thomas NS, Panchagnula R. Transdermal drug delivery of Imipramine hydrochloride I. Effect of terpenes [J]. J Control Release, 2002, 79: 93-101. (Pubitemid 34168193)
30. Narishetty STK, Panchagnula R. Transdermal delivery of zidovudine: effect of terpenes and their mechanism of action [J]. J Control Release, 2004, 95: 367-379. (Pubitemid 38340488)