Involvement of murine β-1,4-galactosyltransferase v in lactosylceramide biosynthesis

Glycoconjugate Journal

Volumn 27, Issue 7-9, 2010, Pages 685-695

  Kumagai, Tadahiro ^a   Sato, Takeshi ^a   Natsuka, Shunji ^b   Kobayashi, Yukito ^a   Zhou, Dapeng ^c   Shinkai, Tadashi ^d   Hayakawa, Satoru ^d   Furukawa, Kiyoshi ^a  

^a NAGAOKA UNIVERSITY OF TECHNOLOGY   (Japan)

^b NIIGATA UNIVERSITY   (Japan)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^d TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

Author keywords

1,4 GalT V; B4galt5 mice; Lactosylceramide; MEF cells

Indexed keywords

BETA 1,4 GALACTOSYLTRANSFERASE I; BETA 1,4 GALACTOSYLTRANSFERASE II; BETA 1,4 GALACTOSYLTRANSFERASE III; BETA 1,4 GALACTOSYLTRANSFERASE IV; BETA 1,4 GALACTOSYLTRANSFERASE V; CERAMIDE GLUCOSYLTRANSFERASE; GALACTOSYLTRANSFERASE; LACTOSYLCERAMIDE; LACTOSYLCERAMIDE SYNTHETASE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE GALACTOSE;

ANIMAL CELL; ARTICLE; BIOSYNTHESIS; CARBOHYDRATE ANALYSIS; CELL GROWTH; CONTROLLED STUDY; EMBRYO CELL; ENZYME ACTIVITY; ENZYME SPECIFICITY; FIBROBLAST; GENE EXPRESSION; MOUSE; NONHUMAN; NULL ALLELE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CARBOHYDRATE INTERACTION;

ANIMALS; ANTIGENS, CD; CELL LINE; CELL PROLIFERATION; FIBROBLASTS; GALACTOSYLTRANSFERASES; GLYCOLIPIDS; GLYCOSYLATION; LACTOSYLCERAMIDES; MEMBRANE GLYCOPROTEINS; MICE; MICE, MUTANT STRAINS; SUBSTRATE SPECIFICITY;

MURINAE; MUS;

EID: 78651234929     PISSN: 02820080     EISSN: 15734986     Source Type: Journal    
DOI: 10.1007/s10719-010-9313-2     Document Type: Article

References (61)

1. L Svennerholm 1994 Designation and schematic structure of gangliosides and allied glycosphingolipids Prog Brain Res 101 11 14
2. MA Surani 1979 Glycoprotein synthesis and inhibition of glycosylation by tunicamycin in preimplantation mouse embryos and compaction and trophoblast adhesion Cell 18 217 227 1:STN:280:DyaL3c%2FmslajsQ%3D%3D 10.1016/0092-8674(79) 90370-2 509524
3. HC Gooi T Feizi A Kapadia BB Knowles D Solter MJ Evans 1981 Stage-specific embryonic antigen involves α1→3 fucosylated type 2 blood group chains Nature 292 156 158 1:CAS:528:DyaL3MXmtFylurw%3D 10.1038/292156a0 6165896 (Pubitemid 11050742)
4. RL Schnaar 1991 Glycosphingolipids in cell surface recognition Glycobiology 1 477 485 1:CAS:528:DyaK38XotV2jsQ%3D%3D 10.1093/glycob/1.5.477 1822229
5. A Varki 1993 Biological roles of oligosaccharides: all of the theories are correct Glycobiology 3 97 130 1:CAS:528:DyaK3sXlsFCju7k%3D 10.1093/glycob/3.2.97 8490246
6. 2+-dependent cell-to-cell adhesion in the Xenopus blastula Dev Genes Evol 208 9 18 1:CAS:528:DyaK1cXislWhsb4%3D 10.1007/s004270050148 9518520 (Pubitemid 28167531)
7. M Metzler A Gertz M Sarkar H Schachter JW Schrader JD Marth 1994 Complex asparagine-linked oligosaccharides are required for morphogenic events during post-implantation development EMBO J 13 2056 2065 1:CAS:528:DyaK2cXksFCmsrg%3D 8187759
8. E Ioffe P Stanley 1994 Mice lacking N-acetylglucosaminyltransferase I activity die at mid-gestation, revealing an essential role for complex or hybrid N-linked carbohydrates Proc Natl Acad Sci USA 91 728 732 1:CAS:528: DyaK2cXhtlWnsLY%3D 10.1073/pnas.91.2.728 8290590
9. M Asano K Furukawa M Kido S Matsumoto Y Umesaki N Kochibe Y Iwakura 1997 Growth retardation and early death of β-1, 4-galactosyltransferase knockout mice with augmented proliferation and abnormal differentiation of epithelial cells EMBO J 16 1850 1857 1:CAS:528:DyaK2sXjt1Wmu78%3D 10.1093/emboj/16.8.1850 9155011 (Pubitemid 27170946)
10. Q Lu P Hasty BD Shur 1997 Targeted mutation in β1, 4-galactosyltransferase leads to pituitary insufficiency and neonatal lethality Dev Biol 181 257 267 1:CAS:528:DyaK2sXpt1OmsA%3D%3D 10.1006/dbio.1996.8444 9013935 (Pubitemid 27089077)
11. T Yamashita R Wada T Sasaki C Deng U Bierfreund K Sandhoff RL Proia 1999 A vital role for glycosphingolipid synthesis during development and differentiation Proc Natl Acad Sci USA 96 9142 9147 1:CAS:528:DyaK1MXltVeqtb8%3D 10.1073/pnas.96.16.9142 10430909 (Pubitemid 29374721)
12. L Xia T Ju A Westmuckett G An L Ivanciu JM McDaniel F Lupu RD Cummings RP McEver 2004 Defective angiogenesis and fatal embryonic hemorrhage in mice lacking core 1-derived O-glycans J Cell Biol 164 451 459 1:CAS:528: DC%2BD2cXhtVahsrk%3D 10.1083/jcb.200311112 14745002 (Pubitemid 38174772)
13. H Habuchi N Nagai N Sugaya F Atsumi RL Stevens K Kimata 2007 Mice deficient in heparan sulfate 6-O-sulfotransferase-1 exhibit defective heparan sulfate biosynthesis, abnormal placentation, and late embryonic lethality J Biol Chem 282 15578 15588 1:CAS:528:DC%2BD2sXltl2gu7g%3D 10.1074/jbc.M607434200 17405882 (Pubitemid 47093285)
14. T Kumagai M Tanaka M Yokoyama T Sato T Shinkai K Furukawa 2009 Early letharity of β-1,4-galactosyltransferase V-mutant mice by growth retardation Biochem Biophys Res Commun 379 456 459 1:CAS:528: DC%2BD1MXotl2iug%3D%3D 10.1016/j.bbrc.2008.12.078 19114028
15. T Yoshihara K Sugihara Y Kizuka S Oka M Asano 2009 Learning/memory impairment and reduced expression of the HNK-1 carbohydrate in β4-galactosyltransferase-II-deficient mice J Biol Chem 284 12550 12561 1:CAS:528:DC%2BD1MXltVClsLw%3D 10.1074/jbc.M809188200 19265195
16. F Biellmann AJ Hulsmeier D Zhou P Cinelli T Hennet 2008 The Lc3-synthase gene B3gnt5 is essential to pre-implantation development of the murine embryo BMC Dev Biol 8 109 10.1186/1471-213X-8-109 19014510
17. K Furukawa K Takamiya M Okada M Inoue S Fukumoto K Furukawa 2001 Novel functions of complex carbohydrates elucidated by the mutant mice of glycosyltransferase genes Biochim Biophys Acta 1525 1 12 1:CAS:528: DC%2BD3MXhtFSrsrw%3D 11342247
18. Furukawa, K., Kobata, A.: Cell surface carbohydrates-their involvement in cell adhesion. In: Ogura, H., Hasegawa, A., Suami, T. (eds.) Carbohydrates Synthetic Methods and Application in Medicinal Chemistry, pp. 369-384. Kodansha, Tokyo (1992)
19. S Chatterjee A Pandey 2008 The Yin and Yang of lactosylceramide metabolism: implications in cell function Biochim Biophys Acta 1780 370 382 1:CAS:528:DC%2BD1cXjsVSisLo%3D 18077097
20. K Furukawa T Sato 1999 β-1,4-galactosylation of N-glycans is a complex process Biochim Biophys Acta 1473 54 66 1:CAS:528:DyaK1MXnsVKmt7Y%3D 10580129
21. T Sato K Furukawa H Bakker DH Van den Eijnden I Van Die 1998 Molecular cloning of a human cDNA encoding β-1,4-galactosyltransferase with 37% identity to mammalian UDP-Gal:GlcNAc β-1,4-galactosyltransferase Proc Natl Acad Sci USA 95 472 477 1:CAS:528:DyaK1cXmtFWktQ%3D%3D 10.1073/pnas.95.2.472 9435216 (Pubitemid 28083767)
22. I Van Die A Van Tetering WECM Schiphorst T Sato K Furukawa DH Van den Eijnden 1999 The acceptor substrate specificity of human β4- galactosyltransferase V indicates its potential function in O-glycosylation FEBS Lett 450 52 56 10.1016/S0014-5793(99)00462-7 10350056 (Pubitemid 29206711)
23. R Almeida M Amado L David SB Levery EH Holmes G Merkx AG van Kessel E Rygaard H Hassan E Bennett H Clausen 1997 A family of human β4- galactosyltransferases J Biol Chem 272 31979 31991 1:CAS:528: DyaK1cXis1Clsw%3D%3D 10.1074/jbc.272.51.31979 9405390 (Pubitemid 28011864)
24. T Schwientek R Almeida SB Levery EH Holmes E Bennett H Clausen 1998 Cloning of a novel member of the UDP-galactose:β-N-acetylglucosamine β1, 4-galactosyltransferase family, β4Gal-T4, involved in glycosphingolipid biosynthesis J Biol Chem 273 29331 29340 1:CAS:528: DyaK1cXntlKqsLk%3D 10.1074/jbc.273.45.29331 9792633 (Pubitemid 28509932)
25. T Nomura M Takizawa J Aoki H Arai K Inoue E Wakisaka N Yoshizuka G Imokawa N Dohmae K Takio M Hattori N Matsuo 1998 Purification, cDNA cloning, and expression of UDP-Gal:glucosylceramide β-1,4-galactosyltransferase from rat brain J Biol Chem 273 13570 13577 1:CAS:528:DyaK1cXjvVejt7g%3D 10.1074/jbc.273.22.13570 9593693 (Pubitemid 28268399)
26. Y Yoshimi T Sato M Ikekita S Guo K Furukawa 2000 Presence of monoantennary complex-type and hybrid-type oligosaccharides terminated with β-N-acetylglucosamine in lepidopteran insect Sf-9 cells Res Commun Biochem Cell Molec Biol 4 163 170 1:CAS:528:DC%2BD3MXmt1Wjs7s%3D
27. JU Baenziger D Fiete 1979 Structural determination of Ricinus communis agglutinin and toxin specificity for oligosaccharides J Biol Chem 254 9795 9799 1:CAS:528:DyaE1MXmtV2juro%3D 489569
28. S Guo T Sato K Shirane K Furukawa 2001 Galactosylation of N-linked oligosaccharides by human β-1,4-galactosyltransferases I, II, III, IV, V, and VI expressed in Sf-9 cells Glycobiology 11 813 820 1:CAS:528: DC%2BD3MXns1Gitr4%3D 10.1093/glycob/11.10.813 11588157
29. N Nakamura N Yamakawa T Sato H Tojo C Tachi K Furukawa 2001 Differential gene expression of β-1, 4-galactosyltransferases I, II and V during mouse brain development J Neurochem 76 29 38 1:CAS:528:DC%2BD3MXhtVGls7s%3D 10.1046/j.1471-4159.2001.00004.x 11145975 (Pubitemid 32044365)
30. T Sato S Guo K Furukawa 2000 Involvement of recombinant human β-1, 4 galactosyltransferase V in lactosylceramide biosynthesis Res Commun Biochem Cell Molec Biol 4 3 10 1:CAS:528:DC%2BD3cXltVCqsrc%3D
31. S Takasaki T Mizuochi A Kobata 1982 Hydrazinolysis of asparaginelinked sugar chains to produce free oligosaccharides Methods Enzymol 83 263 268 1:CAS:528:DyaL38XltVKmtLo%3D 10.1016/0076-6879(82)83019-X 7098932
32. S Hase T Ikenaka Y Matsushima 1978 Structural analysis of oligosaccharides by tagging of the reducing end sugars with a fluorescent compound Biochem Biophys Res Commun 85 257 263 1:CAS:528:DyaE1MXmvVOitw%3D%3D 10.1016/S0006-291X(78)80037-0 743278
33. K Yanagida H Ogawa K Omichi S Hase 1998 Introduction of new scale into reversed-phase high-performance liquid chromatography of pyridylamino sugar chains for structural assignment J Chromatogr 800 187 198 1:CAS:528: DyaK1cXhs1GhsLc%3D 10.1016/S0021-9673(97)01109-6 (Pubitemid 28164293)
34. T Sato K Furukawa DE Greenwalt A Kobata 1993 Most bovine milk fat globule membrane glycoproteins contain asparagine linked sugar chain with GalNAcβ1→4GlcNAc groups J Biochem (Tokyo) 117 890 900
35. S Ando H Waki K Kon 1987 New solvent system for high-performance thin-layer chromatography and high-performance liquid chromatography of gangliosides J Chromatogr 405 125 134 1:CAS:528:DyaL2sXlsFSmtL0%3D 10.1016/S0021-9673(01)81754-4 3693462
36. Y Li P Thapa D Hawke Y Kondo K Furukawa K Furukawa F-F Hsu D Aldercreutz J Weadge MM Palcic PG Wang SB Levery D Zhou 2009 Immunologic glycoshingolipidomics and NKT cell development in mouse thymus J Proteome Res 8 2740 2751 1:CAS:528:DC%2BD1MXltVCgsb8%3D 10.1021/pr801040h 19284783
37. HB Guo A Nairn K Harris M Randolph G Alvarez-Manilla M Moremen Pierce 2008 Loss of expression of N-acetylglucosaminyltransferase Va results in altered gene expression of glycosyltransferases and galectins FEBS Lett 582 527 535 1:CAS:528:DC%2BD1cXhslejt70%3D 10.1016/j.febslet.2008.01.015 18230362
38. S Natsuka J Adachi M Kawaguchi A Ichikawa K Ikura 2002 Method for purification of fluorescence-labeled oligosaccharides by pyridylamination Biosci Biotechnol Biochem 66 1174 1175 1:CAS:528:DC%2BD38XktlSrsLY%3D 10.1271/bbb.66.1174 12092840
39. N Shibuya IJ Goldstein WF Broekaert M Nshimba-Lubaki B Peeters WJ Peumans 1987 The elderberry (Sambucus nigra) bark lectin recognizes the Neu5Ac(α2-6)Gal/GalNAc sequence J Biol Chem 262 1596 1601 1:CAS:528:DyaL2sXhslWns7s%3D 3805045
40. WC Wang RD Cummings 1988 The immobilized leukoagglutinin from the seeds of Maackia amurensis binds with high affinity to complex-type Asn-linked oligosaccharides containing terminal sialic acid-linked α-2,3 to penultimate galactose residues J Biol Chem 263 4576 4585 1:CAS:528: DyaL1cXktValsLo%3D 3350806
41. S Ogata T Muramatsu A Kobata 1975 Fractionation of glycopeptides by affinity column chromatography on concanavalin A-Sepharose J Biochem (Tokyo) 78 687 696 1:CAS:528:DyaE28XhvVOk
42. RK Merkle RD Cummings 1987 Lectin affinity chromatography of glycoproteins Methods Enzymol 138 232 259 1:CAS:528:DyaL2sXkvFaqsr8%3D 10.1016/0076-6879(87)38020-6 3600324
43. R Lotan E Skutelsky D Danon N Sharon 1975 The purification, composition, and specificity of the anti-T lectin from peanut (Arachis hypogaea) J Biol Chem 250 8518 8523 1:CAS:528:DyaE28XktFOmuw%3D%3D 811657
44. K Nakazawa K Furukawa H Narimatsu A Kobata 1993 Kinetic study of human β-1,4-galactosyltransferase expressed in E. coli. J Biochem (Tokyo) 113 747 753 1:CAS:528:DyaK3sXltlChsLs%3D
45. A Regina-Todeschini S Hakomori 2008 Functional role of glycosphingolipids and gangliosides in control of cell adhesion, motility, and growth, through glycosynaptic microdomains Biochim Biophys Acta 1780 421 433 1:CAS:528:DC%2BD1cXjsVSisLc%3D 17991443
46. T Yamashita A Hashiramoto M Haluzik H Mizukami S Beck A Norton M Kono S Tsuji JL Daniotti N Werth R Sandhoff K Sandhoff RL Proia 2003 Enhanced insulin sensitivity in mice lacking ganglioside GM3 Proc Natl Acad Sci USA 100 3445 3449 1:CAS:528:DC%2BD3sXisVCnurk%3D 10.1073/pnas.0635898100 12629211 (Pubitemid 36356603)
47. T Okuda N Tokuda S Numata M Ito M Ohta K Kawamura J Wiels T Urano O Tajima K Furukawa K Furukawa 2006 Targeted disruption of Gb3/CD77 synthase gene resulted in the complete deletion of globo-series glycosphingolipids and loss of sensitivity to verotoxins J Biol Chem 281 10230 10232 1:CAS:528: DC%2BD28Xjt1Knsr8%3D 10.1074/jbc.M600057200 16476743 (Pubitemid 43864560)
48. Y Kawakami K Kawakami WF Steelant M Ono RC Baek K Handa DA Withers S Hakomori 2002 Tetraspanin CD9 is a "proteolipid," and its interaction with α3 integrin in microdomain is promoted by GM3 ganglioside, leading to inhibition of laminin-5-dependent cell motility J Biol Chem 277 34349 34358 1:CAS:528:DC%2BD38Xnt1Wjs7o%3D 10.1074/jbc.M200771200 12068006
49. K Mitsuzuka K Handa M Satoh Y Arai S Hakomori 2005 A specific microdomain ("glycosynapse 3") controls phenotypic conversion and reversion of bladder cancer cells through GM3-mediated interaction of α3β1 integrin with CD9 J Biol Chem 280 35545 35553 1:CAS:528:DC%2BD2MXhtFWmur3F 10.1074/jbc.M505630200 16103120 (Pubitemid 41532746)
50. SJ Yoon K Nakayama T Hikita K Handa S Hakomori 2005 Epidermal growth factor receptor tyrosine kinase is modulated by GM3 interaction with N-linked GlcNAc termini of the receptor Proc Natl Acad Sci USA 50 18987 18991
51. DS Harburger DA Calderwood 2009 Integrin signalling at a glance J Cell Sci 122 159 163 1:CAS:528:DC%2BD1MXit1GqtLw%3D 10.1242/jcs.018093 19118207
52. W Xu H Baribault ED Adamson 1998 Vinculin knockout results in heart and brain defects during embryonic development Development 125 327 337 1:CAS:528:DyaK1cXhtlGgtbY%3D 9486805
53. SJ Monkley XH Zhou SJ Kinston SM Giblett L Hemmings H Priddle JE Brown CA Pritchard DR Critchley R Fässler 2000 Disruption of the talin gene arrests mouse development at the gastrulation stage Dev Dyn 219 560 574 1:CAS:528:DC%2BD3cXovVSgtrs%3D 10.1002/1097-0177(2000)9999:9999<::AID- DVDY1079>3.0.CO;2-Y 11084655
54. M Hagel EL George A Kim R Tamimi SL Opitz CE Turner A Imamoto SM Thomas 2002 The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling Mol Cell Biol 22 901 915 1:CAS:528:DC%2BD38Xmt12ntg%3D%3D 10.1128/MCB.22.3.901-915.2002 11784865
55. D Ilić Y Furuta S Kanazawa N Takeda K Sobue N Nakatsuji S Nomura J Fujimoto M Okada T Yamamoto 1995 Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice Nature 377 539 544 10.1038/377539a0 7566154
56. K Takamiya A Yamamoto K Furukawa S Yamashiro M Shin M Okada S Fukumoto M Haraguchi N Takeda K Fujimura M Sakae M Kishikawa H Shiku K Furukawa S Aizawa 1996 Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system Proc Natl Acad Sci USA 93 10662 10667 1:CAS:528:DyaK28XmtVOlt78%3D 10.1073/pnas.93.20.10662 8855236 (Pubitemid 26333045)
57. KA Sheikh J Sun Y Liu H Kawai TO Crawford RL Proia JW Griffin RL Schnaar 1999 Mice lacking complex gangliosides develop Wallerian degeneration and myelination defects Proc Natl Acad Sci USA 96 7532 7537 1:CAS:528: DyaK1MXltVOqsLk%3D 10.1073/pnas.96.13.7532 10377449 (Pubitemid 29299696)
58. H Kawai ML Allende R Wada M Kono K Sango C Deng T Miyakawa JN Crawley N Werth U Bierfreund K Sandhoff RL Proia 2001 Mice expressing only monosialoganglioside GM3 exhibit lethal audiogenic seizures J Biol Chem 276 6885 6888 1:CAS:528:DC%2BD3MXitVKlsb8%3D 10.1074/jbc.C000847200 11133999
59. M Okada M Itoh M Haraguchi T Okajima M Inoue H Oishi Y Matsuda T Iwamoto T Kawano S Fukumoto H Miyazaki K Furukawa S Aizawa K Furukawa 2002 b-series Ganglioside deficiency exhibits no definite changes in the neurogenesis and the sensitivity to Fas-mediated apoptosis but impairs regeneration of the lesioned hypoglossal nerve J Biol Chem 277 1633 1636 1:CAS:528:DC%2BD38XosFaqtQ%3D%3D 10.1074/jbc.C100395200 11682464 (Pubitemid 34968730)
60. T Okuda N Tokuda S Numata M Ito M Ohta K Kawamura J Wiels T Urano O Tajima K Furukawa K Furukawa 2006 Targeted disruption of Gb3/CD77 synthase gene resulted in the complete deletion of globo-series glycosphingolipids and loss of sensitivity to verotoxins J Biol Chem 281 10230 10232 1:CAS:528: DC%2BD28Xjt1Knsr8%3D 10.1074/jbc.M600057200 16476743 (Pubitemid 43864560)
61. S Porubsky AO Speak B Luckow V Cerundolo FM Platt H Gröne 2007 Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency Proc Natl Acad Sci USA 104 5977 5982 1:CAS:528:DC%2BD2sXkt1Gjsbg%3D 10.1073/pnas.0611139104 17372206 (Pubitemid 47175644)