New azoles with antifungal activity: Design, synthesis, and molecular docking

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 2, 2011, Pages 686-689

  Chai, Xiaoyun ^a   Zhang, Jun ^a   Cao, Yongbing ^a   Zou, Yan ^a   Wu, Qiuye ^a   Zhang, Dazhi ^a   Jiang, Yuanying ^a   Sun, Qingyan ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Antifungal activity; Azole; CYP51; Molecular docking; Synthesis

Indexed keywords

PYRROLE DERIVATIVE;

ANTIFUNGAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; MOLECULAR DOCKING; NONHUMAN;

14-ALPHA DEMETHYLASE INHIBITORS; ANTIFUNGAL AGENTS; AZOLES; FUNGI; HUMANS; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; MYCOSES; PROTEIN BINDING; STEROL 14-DEMETHYLASE; STRUCTURE-ACTIVITY RELATIONSHIP;

FUNGI;

EID: 78651233022     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.12.006     Document Type: Article

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