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Volumn 6, Issue 12, 2010, Pages

Phase-locked signals elucidate circuit architecture of an oscillatory pathway

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CHEMICAL ANALYSIS; ELECTRIC NETWORK ANALYSIS; LOCKS (FASTENERS); SIGNAL PROCESSING; SIGNALING;

EID: 78651229043     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1001040     Document Type: Article
Times cited : (36)

References (62)
  • 1
    • 37349129852 scopus 로고    scopus 로고
    • STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2+ levels
    • Brandman O, Liou J, Park WS, Meyer T (2007) STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2+ levels. Cell 131: 1327-1339.
    • (2007) Cell , vol.131 , pp. 1327-1339
    • Brandman, O.1    Liou, J.2    Park, W.S.3    Meyer, T.4
  • 2
    • 21844432686 scopus 로고    scopus 로고
    • STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx
    • Liou J, Kim ML, Heo WD, Jones JT, Myers JW, et al. (2005) STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx. Curr Biol 15: 1235-1241.
    • (2005) Curr Biol , vol.15 , pp. 1235-1241
    • Liou, J.1    Kim, M.L.2    Heo, W.D.3    Jones, J.T.4    Myers, J.W.5
  • 4
    • 0027486748 scopus 로고
    • The Inositol Phosphate-Calcium Signaling System in Nonexcitable Cells
    • Putney JW, Bird GS (1993) The Inositol Phosphate-Calcium Signaling System in Nonexcitable Cells. Endocr Rev 14: 610-631.
    • (1993) Endocr Rev , vol.14 , pp. 610-631
    • Putney, J.W.1    Bird, G.S.2
  • 5
    • 32444447226 scopus 로고    scopus 로고
    • A method for determining the dependence of calcium oscillations on inositol trisphosphate oscillations
    • Sneyd J, Tsaneva-Atanasova K, Reznikov V, Bai Y, Sanderson MJ, et al. (2006) A method for determining the dependence of calcium oscillations on inositol trisphosphate oscillations. Proc Natl Acad Sci USA 103: 1675-1680.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 1675-1680
    • Sneyd, J.1    Tsaneva-Atanasova, K.2    Reznikov, V.3    Bai, Y.4    Sanderson, M.J.5
  • 6
    • 0019815049 scopus 로고
    • Phase Locking, Period-Doubling Bifurcations, and Irregular Dynamics in Periodically Stimulated Cardiac-Cells
    • Guevara MR, Glass L, Shrier A (1981) Phase Locking, Period-Doubling Bifurcations, and Irregular Dynamics in Periodically Stimulated Cardiac-Cells. Science 214: 1350-1353.
    • (1981) Science , vol.214 , pp. 1350-1353
    • Guevara, M.R.1    Glass, L.2    Shrier, A.3
  • 7
    • 0028871337 scopus 로고
    • In vitro study of phase resetting and phase locking in a timecomparison circuit in the electric fish, Eigenmannia
    • Wessel R (1995) In vitro study of phase resetting and phase locking in a timecomparison circuit in the electric fish, Eigenmannia. Biophys J 69: 1880-1890.
    • (1995) Biophys J , vol.69 , pp. 1880-1890
    • Wessel, R.1
  • 8
    • 55149109908 scopus 로고    scopus 로고
    • Simplified model of cytosolic Ca2+ dynamics in the presence of one or several clusters of Ca2+- release channels
    • Solovey G, Fraiman D, Pando B, Ponce Dawson S (2008) Simplified model of cytosolic Ca2+ dynamics in the presence of one or several clusters of Ca2+- release channels. Phys Rev E 78: 041915.
    • (2008) Phys Rev E , vol.78 , pp. 041915
    • Solovey, G.1    Fraiman, D.2    Pando, B.3    Ponce Dawson, S.4
  • 10
    • 0029061307 scopus 로고
    • Appearance of phase-locked Wenckebach-like rhythms, devil's staircase and unviersality in intracellular calcium spikes in nonexcitable cell models
    • Chay TR, Lee YS, Fan YS (1995) Appearance of phase-locked Wenckebach-like rhythms, devil's staircase and unviersality in intracellular calcium spikes in nonexcitable cell models. J Theor Biol 174: 21-44.
    • (1995) J Theor Biol , vol.174 , pp. 21-44
    • Chay, T.R.1    Lee, Y.S.2    Fan, Y.S.3
  • 11
    • 33646153534 scopus 로고    scopus 로고
    • Models of IP3 and Ca2+ oscillations: Frequency encoding and identification of underlying feedbacks
    • Politi A, Gaspers LD, Thomas AP, Hofer T (2006) Models of IP3 and Ca2+ oscillations: Frequency encoding and identification of underlying feedbacks. Biophys J 90: 3120-3133.
    • (2006) Biophys J , vol.90 , pp. 3120-3133
    • Politi, A.1    Gaspers, L.D.2    Thomas, A.P.3    Hofer, T.4
  • 12
    • 0030064650 scopus 로고    scopus 로고
    • Calcium dependence of calcium extrusion and calcium uptake in mouse pancreatic acinar cells
    • Camello P, Gardner J, Petersen OH, Tepikin AV (1996) Calcium dependence of calcium extrusion and calcium uptake in mouse pancreatic acinar cells. J Physiol (Lond) 490: 585-593.
    • (1996) J Physiol (Lond) , vol.490 , pp. 585-593
    • Camello, P.1    Gardner, J.2    Petersen, O.H.3    Tepikin, A.V.4
  • 13
    • 0028178965 scopus 로고
    • Equations for INSP(3) Receptor-mediated [Ca2+](i) oscillations derived from a detailed kinetic-model- a Hodgkin-Huxley-like formalism
    • Li YX, Rinzel J (1994) Equations for INSP(3) Receptor-mediated [Ca2+](i) oscillations derived from a detailed kinetic-model- a Hodgkin-Huxley-like formalism. J Theor Biol 166: 461-473.
    • (1994) J Theor Biol , vol.166 , pp. 461-473
    • Li, Y.X.1    Rinzel, J.2
  • 14
    • 0026691835 scopus 로고
    • Functional Comparisons between Isoforms of the Sarcoplasmic or Endoplasmic-Reticulum Family of Calcium Pumps
    • Lytton J, Westlin M, Burk SE, Shull GE, Maclennan DH (1992) Functional Comparisons between Isoforms of the Sarcoplasmic or Endoplasmic-Reticulum Family of Calcium Pumps. J Biol Chem 267: 14483-14489.
    • (1992) J Biol Chem , vol.267 , pp. 14483-14489
    • Lytton, J.1    Westlin, M.2    Burk, S.E.3    Shull, G.E.4    Maclennan, D.H.5
  • 15
    • 33748786047 scopus 로고    scopus 로고
    • Modeling IP3-dependent calcium dynamics in non-excitable cells
    • Sneyd J (2005) Modeling IP3-dependent calcium dynamics in non-excitable cells. Tutor Math Biosci II 1867: 15-61.
    • (2005) Tutor Math Biosci , vol.2 , Issue.1867 , pp. 15-61
    • Sneyd, J.1
  • 16
    • 0027421180 scopus 로고
    • A Single-Pool Model for Intracellular Calcium Oscillations and Waves in the Xenopus-Laevis Oocyte
    • Atri A, Amundson J, Clapham D, Sneyd J (1993) A Single-Pool Model for Intracellular Calcium Oscillations and Waves in the Xenopus-Laevis Oocyte. Biophys J 65: 1727-1739.
    • (1993) Biophys J , vol.65 , pp. 1727-1739
    • Atri, A.1    Amundson, J.2    Clapham, D.3    Sneyd, J.4
  • 17
    • 0030786064 scopus 로고    scopus 로고
    • Simulations of the effects of inositol 1,4,5- trisphosphate 3-kinase and 5-phosphatase activities on Ca2+ oscillations
    • Dupont G, Erneux C (1997) Simulations of the effects of inositol 1,4,5- trisphosphate 3-kinase and 5-phosphatase activities on Ca2+ oscillations. Cell Calcium 22: 321-331.
    • (1997) Cell Calcium , vol.22 , pp. 321-331
    • Dupont, G.1    Erneux, C.2
  • 18
    • 0028178965 scopus 로고
    • Equations for Insp(3) Receptor-Mediated [Ca2+](I) Oscillations Derived from a Detailed Kinetic-Model - a Hodgkin-Huxley Like Formalism
    • Li YX, Rinzel J (1994) Equations for Insp(3) Receptor-Mediated [Ca2+](I) Oscillations Derived from a Detailed Kinetic-Model - a Hodgkin-Huxley Like Formalism. J Theor Biol 166: 461-473.
    • (1994) J Theor Biol , vol.166 , pp. 461-473
    • Li, Y.X.1    Rinzel, J.2
  • 19
    • 70450257869 scopus 로고    scopus 로고
    • Effectors of the frequency of calcium oscillations in HEK-293 cells: Wavelet analysis and a computer model
    • Szekely D, Brennan SC, Mun HC, Conigrave AD, Kuchel PW (2009) Effectors of the frequency of calcium oscillations in HEK-293 cells: wavelet analysis and a computer model. Eur Biophys J 39: 149-165.
    • (2009) Eur Biophys J , vol.39 , pp. 149-165
    • Szekely, D.1    Brennan, S.C.2    Mun, H.C.3    Conigrave, A.D.4    Kuchel, P.W.5
  • 20
    • 0023789925 scopus 로고
    • Repetitive spikes in cytoplasmic calcium evoked by histamine in human endothelial cells
    • Jacob R, Merritt JE, Hallam TJ, Rink TJ (1988) Repetitive spikes in cytoplasmic calcium evoked by histamine in human endothelial cells. Nature 335: 40-45.
    • (1988) Nature , vol.335 , pp. 40-45
    • Jacob, R.1    Merritt, J.E.2    Hallam, T.J.3    Rink, T.J.4
  • 21
    • 0023800051 scopus 로고
    • Cell-specific patterns of oscillating free Ca2+ in carbamylcholinestimulated insulinoma cells
    • Prentki M, Glennon MC, Thomas AP, Morris RL, Matschinsky FM, et al. (1988) Cell-specific patterns of oscillating free Ca2+ in carbamylcholinestimulated insulinoma cells. J Biol Chem 263: 11044-11047.
    • (1988) J Biol Chem , vol.263 , pp. 11044-11047
    • Prentki, M.1    Glennon, M.C.2    Thomas, A.P.3    Morris, R.L.4    Matschinsky, F.M.5
  • 22
    • 0022575044 scopus 로고
    • Repetitive transient rises in cytoplasmic free calcium in hormone-stimulated hepatocytes
    • Woods NM, Cuthbertson KS, Cobbold PH (1986) Repetitive transient rises in cytoplasmic free calcium in hormone-stimulated hepatocytes. Nature 319: 600-602.
    • (1986) Nature , vol.319 , pp. 600-602
    • Woods, N.M.1    Cuthbertson, K.S.2    Cobbold, P.H.3
  • 23
    • 0019224260 scopus 로고
    • Driven Oscillations of a Limit-Cycle Oscillator
    • Machlup S, Sluckin TJ (1980) Driven Oscillations of a Limit-Cycle Oscillator. J Theor Biol 84: 119-134.
    • (1980) J Theor Biol , vol.84 , pp. 119-134
    • Machlup, S.1    Sluckin, T.J.2
  • 24
    • 77951763153 scopus 로고    scopus 로고
    • Periodic cyclin-Cdk activity entrains an autonomous Cdc14 release oscillator
    • Lu Y, Cross FR. Periodic cyclin-Cdk activity entrains an autonomous Cdc14 release oscillator. Cell 141: 268-279.
    • Cell , vol.141 , pp. 268-279
    • Lu, Y.1    Cross, F.R.2
  • 25
    • 33644841800 scopus 로고    scopus 로고
    • Handheld recirculation system and customized media for microfluidic cell culture
    • Futai N, Gu W, Song JW, Takayama S (2006) Handheld recirculation system and customized media for microfluidic cell culture. Lab Chip 6: 149-154.
    • (2006) Lab Chip , vol.6 , pp. 149-154
    • Futai, N.1    Gu, W.2    Song, J.W.3    Takayama, S.4
  • 26
    • 0035874471 scopus 로고    scopus 로고
    • Single-cell imaging of graded Ins(1,4,5)P-3 production following G-protein-coupledreceptor activation
    • Nash MS, Young KW, Willars GB, Challiss RAJ, Nahorski SR (2001) Single-cell imaging of graded Ins(1,4,5)P-3 production following G-protein-coupledreceptor activation. Biochem J 356: 137-142.
    • (2001) Biochem J , vol.356 , pp. 137-142
    • Nash, M.S.1    Young, K.W.2    Willars, G.B.3    Challiss, R.A.J.4    Nahorski, S.R.5
  • 27
    • 0032580202 scopus 로고    scopus 로고
    • Calcium oscillations increase the efficiency and specificity of gene expression
    • Dolmetsch RE, Xu KL, Lewis RS (1998) Calcium oscillations increase the efficiency and specificity of gene expression. Nature 392: 933-936.
    • (1998) Nature , vol.392 , pp. 933-936
    • Dolmetsch, R.E.1    Xu, K.L.2    Lewis, R.S.3
  • 28
    • 0030888186 scopus 로고    scopus 로고
    • Differential activation of transcription factors induced by Ca2+ response amplitude and duration
    • Dolmetsch RE, Lewis RS, Goodnow CC, Healy JI (1997) Differential activation of transcription factors induced by Ca2+ response amplitude and duration. Nature 386: 855-858.
    • (1997) Nature , vol.386 , pp. 855-858
    • Dolmetsch, R.E.1    Lewis, R.S.2    Goodnow, C.C.3    Healy, J.I.4
  • 29
    • 21644438992 scopus 로고    scopus 로고
    • Precision of intracellular calcium spike timing in primary rat hepatocytes
    • Prank K, Waring M, Ahlvers U, Bader A, Penner E, et al. (2005) Precision of intracellular calcium spike timing in primary rat hepatocytes. Syst Biol 2: 31-34.
    • (2005) Syst Biol , vol.2 , pp. 31-34
    • Prank, K.1    Waring, M.2    Ahlvers, U.3    Bader, A.4    Penner, E.5
  • 30
    • 33847795362 scopus 로고    scopus 로고
    • A quantitative kinetic model for ATPinduced intracellular Ca2+ oscillations
    • Wang JH, Huang XD, Huang WD (2007) A quantitative kinetic model for ATPinduced intracellular Ca2+ oscillations. J Theor Biol 245: 510-519.
    • (2007) J Theor Biol , vol.245 , pp. 510-519
    • Wang, J.H.1    Huang, X.D.2    Huang, W.D.3
  • 31
    • 62549154852 scopus 로고    scopus 로고
    • Stimulus perturbation induced signal: A case study in mesoscopic intracellular calcium system
    • Ji L, Lang XF, Li YP, Li QS (2009) Stimulus perturbation induced signal: A case study in mesoscopic intracellular calcium system. Biophys Chem 141: 231-235.
    • (2009) Biophys Chem , vol.141 , pp. 231-235
    • Ji, L.1    Lang, X.F.2    Li, Y.P.3    Li, Q.S.4
  • 32
    • 0025144620 scopus 로고
    • Computer-Simulation of a Cytosolic Calcium Oscillator
    • Swillens S, Mercan D (1990) Computer-Simulation of a Cytosolic Calcium Oscillator. Biochem J 271: 835-838.
    • (1990) Biochem J , vol.271 , pp. 835-838
    • Swillens, S.1    Mercan, D.2
  • 33
    • 68949090231 scopus 로고    scopus 로고
    • Synchronization of pancreatic islet oscillations by intrapancreatic ganglia: A modeling study
    • Fendler B, Zhang M, Satin L, Bertram R (2009) Synchronization of pancreatic islet oscillations by intrapancreatic ganglia: a modeling study. Biophys J 97: 722-729.
    • (2009) Biophys J , vol.97 , pp. 722-729
    • Fendler, B.1    Zhang, M.2    Satin, L.3    Bertram, R.4
  • 34
    • 77954596479 scopus 로고    scopus 로고
    • Global Entrainment of Transcriptional Systems to Periodic Inputs
    • Russo G, di Bernardo M, Sontag ED (2010) Global Entrainment of Transcriptional Systems to Periodic Inputs. PLoS Comput Biol 6(4): e1000739.
    • (2010) PLoS Comput Biol , vol.6 , Issue.4
    • Russo, G.1    di Bernardo, M.2    Sontag, E.D.3
  • 35
    • 0024454029 scopus 로고
    • Trypanosoma-Cruzi - Infection of Cultured Human-Endothelial Cells Alters Inositol Phosphate Synthesis
    • Morris SA, Bilezikian JP, Hatcher V, Weiss LM, Tanowitz HB, et al. (1989) Trypanosoma-Cruzi - Infection of Cultured Human-Endothelial Cells Alters Inositol Phosphate Synthesis. Exp Parasitol 69: 330-339.
    • (1989) Exp Parasitol , vol.69 , pp. 330-339
    • Morris, S.A.1    Bilezikian, J.P.2    Hatcher, V.3    Weiss, L.M.4    Tanowitz, H.B.5
  • 36
    • 0031033944 scopus 로고    scopus 로고
    • Synergism of constitutive activity in alpha(1)-adrenergic receptor activation
    • Hwa J, Gaivin R, Porter JE, Perez DM (1997) Synergism of constitutive activity in alpha(1)-adrenergic receptor activation. Biochem 36: 633-639.
    • (1997) Biochem , vol.36 , pp. 633-639
    • Hwa, J.1    Gaivin, R.2    Porter, J.E.3    Perez, D.M.4
  • 37
    • 0023819320 scopus 로고
    • Formation and Metabolism of [H-3]Inositol Phosphates in Ar42j Pancreatoma Cells - Substance P-Induced Ca-2+ Mobilization in the Apparent Absence of Inositol 1,4,5-Trisphosphate 3- Kinase Activity
    • Horstman DA, Takemura H, Putney JW (1988) Formation and Metabolism of [H-3]Inositol Phosphates in Ar42j Pancreatoma Cells - Substance P-Induced Ca-2+ Mobilization in the Apparent Absence of Inositol 1,4,5-Trisphosphate 3- Kinase Activity. J Biol Chem 263: 15297-15303.
    • (1988) J Biol Chem , vol.263 , pp. 15297-15303
    • Horstman, D.A.1    Takemura, H.2    Putney, J.W.3
  • 38
    • 0025752377 scopus 로고
    • Modeling receptor-controlled intracellular calcium oscillators
    • Cuthbertson KSR, Chay TR (1991) Modeling receptor-controlled intracellular calcium oscillators. Cell Calcium 12: 97-109.
    • (1991) Cell Calcium , vol.12 , pp. 97-109
    • Cuthbertson, K.S.R.1    Chay, T.R.2
  • 39
  • 40
    • 0018647858 scopus 로고
    • A simple model for phase locking of biological oscillators
    • Glass L, Mackey MC (1979) A simple model for phase locking of biological oscillators. J Math Biol 7: 339-352.
    • (1979) J Math Biol , vol.7 , pp. 339-352
    • Glass, L.1    Mackey, M.C.2
  • 41
    • 50649111625 scopus 로고    scopus 로고
    • Systems biology - Reverse engineering the cell
    • Ingolia NT, Weissman JS (2008) Systems biology - Reverse engineering the cell. Nature 454: 1059-1062.
    • (2008) Nature , vol.454 , pp. 1059-1062
    • Ingolia, N.T.1    Weissman, J.S.2
  • 43
  • 44
    • 71449121678 scopus 로고    scopus 로고
    • Rapid and sustained nuclear-cytoplasmic ERK oscillations induced by epidermal growth factor
    • Shankaran H, Ippolito DL, Chrisler WB, Resat H, Bollinger N, et al. (2009) Rapid and sustained nuclear-cytoplasmic ERK oscillations induced by epidermal growth factor. Mol Syst Biol 5: 332.
    • (2009) Mol Syst Biol , vol.5 , pp. 332
    • Shankaran, H.1    Ippolito, D.L.2    Chrisler, W.B.3    Resat, H.4    Bollinger, N.5
  • 45
    • 7444254365 scopus 로고    scopus 로고
    • Oscillations in NF-kappa B signaling control the dynamics of gene expression
    • Nelson DE, Ihekwaba AEC, Elliott M, Johnson JR, Gibney CA, et al. (2004) Oscillations in NF-kappa B signaling control the dynamics of gene expression. Science 306: 704-708.
    • (2004) Science , vol.306 , pp. 704-708
    • Nelson, D.E.1    Ihekwaba, A.E.C.2    Elliott, M.3    Johnson, J.R.4    Gibney, C.A.5
  • 46
    • 0033593306 scopus 로고    scopus 로고
    • Molecular bases for circadian clocks
    • Dunlap JC (1999) Molecular bases for circadian clocks. Cell 96: 271-290.
    • (1999) Cell , vol.96 , pp. 271-290
    • Dunlap, J.C.1
  • 47
    • 69949126005 scopus 로고    scopus 로고
    • Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription
    • Stavreva DA, Wiench M, John S, Conway-Campbell BL, McKenna MA, et al. (2009) Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription. Nat Cell Biol 11: 1093-U1111.
    • (2009) Nat Cell Biol , vol.11
    • Stavreva, D.A.1    Wiench, M.2    John, S.3    Conway-Campbell, B.L.4    McKenna, M.A.5
  • 48
    • 0032758081 scopus 로고    scopus 로고
    • A simple model of circadian rhythms based on dimerization and proteolysis of PER and TIM
    • Tyson JJ, Hong CI, Thron CD, Novak B (1999) A simple model of circadian rhythms based on dimerization and proteolysis of PER and TIM. Biophys J 77: 2411-2417.
    • (1999) Biophys J , vol.77 , pp. 2411-2417
    • Tyson, J.J.1    Hong, C.I.2    Thron, C.D.3    Novak, B.4
  • 49
    • 0029094843 scopus 로고
    • A Model for Circadian Oscillations in the Drosophila Period Protein (Per)
    • Goldbeter A (1995) A Model for Circadian Oscillations in the Drosophila Period Protein (Per). Proc R Soc Lond Ser B Biol Sci 261: 319-324.
    • (1995) Proc R Soc Lond Ser B Biol Sci , vol.261 , pp. 319-324
    • Goldbeter, A.1
  • 50
    • 3242706582 scopus 로고    scopus 로고
    • Expanded dynamic range of fluorescent indicators for Ca2+ by circularly permuted yellow fluorescent proteins
    • Nagai T, Yamada S, Tominaga T, Ichikawa M, Miyawaki A (2004) Expanded dynamic range of fluorescent indicators for Ca2+ by circularly permuted yellow fluorescent proteins. Proc Natl Acad Sci USA 101: 10554-10559.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 10554-10559
    • Nagai, T.1    Yamada, S.2    Tominaga, T.3    Ichikawa, M.4    Miyawaki, A.5
  • 52
    • 4544236971 scopus 로고    scopus 로고
    • Rapid prototyping of microstructures with bell-shaped cross-sections and its application to deformation-based microfluidic valves
    • Futai N, Gu W, Takayama S (2004) Rapid prototyping of microstructures with bell-shaped cross-sections and its application to deformation-based microfluidic valves. Adv Mater 16: 1320-1323.
    • (2004) Adv Mater , vol.16 , pp. 1320-1323
    • Futai, N.1    Gu, W.2    Takayama, S.3
  • 53
    • 8644241679 scopus 로고    scopus 로고
    • Computerized microfluidic cell culture using elastomeric channels and Braille displays
    • Gu W, Zhu XY, Futai N, Cho BS, Takayama S (2004) Computerized microfluidic cell culture using elastomeric channels and Braille displays. Proc Natl Acad Sci USA 101: 15861-15866.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 15861-15866
    • Gu, W.1    Zhu, X.Y.2    Futai, N.3    Cho, B.S.4    Takayama, S.5
  • 54
    • 34347230164 scopus 로고    scopus 로고
    • Measuring calcium signaling using genetically targetable fluorescent indicators
    • Palmer AE, Tsien RY (2006) Measuring calcium signaling using genetically targetable fluorescent indicators. Nat Protoc 1: 1057-1065.
    • (2006) Nat Protoc , vol.1 , pp. 1057-1065
    • Palmer, A.E.1    Tsien, R.Y.2
  • 55
    • 33846999007 scopus 로고    scopus 로고
    • Characterization and resolution of evaporation-mediated osmolality shifts that constrain microfluidic cell culture in poly(dimethylsiloxane) devices
    • Heo YS, Cabrera LM, Song JW, Futai N, Tung YC, et al. (2007) Characterization and resolution of evaporation-mediated osmolality shifts that constrain microfluidic cell culture in poly(dimethylsiloxane) devices. Anal Chem 79: 1126-1134.
    • (2007) Anal Chem , vol.79 , pp. 1126-1134
    • Heo, Y.S.1    Cabrera, L.M.2    Song, J.W.3    Futai, N.4    Tung, Y.C.5
  • 56
    • 0036696824 scopus 로고    scopus 로고
    • Lateral propagation of EGF signaling after local stimulation is dependent on receptor density
    • Sawano A, Takayama S, Matsuda M, Miyawaki A (2002) Lateral propagation of EGF signaling after local stimulation is dependent on receptor density. Dev Cell 3: 245-257.
    • (2002) Dev Cell , vol.3 , pp. 245-257
    • Sawano, A.1    Takayama, S.2    Matsuda, M.3    Miyawaki, A.4
  • 57
    • 0027975229 scopus 로고
    • Calcium Signaling in Individual Bc(3)H1 Cells - Speed of Calcium Mobilization and Heterogeneity
    • Mahama PA, Linderman JJ (1994) Calcium Signaling in Individual Bc(3)H1 Cells - Speed of Calcium Mobilization and Heterogeneity. Biotechnol Prog 10: 45-54.
    • (1994) Biotechnol Prog , vol.10 , pp. 45-54
    • Mahama, P.A.1    Linderman, J.J.2
  • 58
    • 0035937155 scopus 로고    scopus 로고
    • Signaling pathways underlying muscarinic receptor-induced [Ca2+](i) oscillations in HEK293 cells
    • Luo D, Broad LM, Bird GSJ, Putney JW (2001) Signaling pathways underlying muscarinic receptor-induced [Ca2+](i) oscillations in HEK293 cells. J Biol Chem 276: 5613-5621.
    • (2001) J Biol Chem , vol.276 , pp. 5613-5621
    • Luo, D.1    Broad, L.M.2    Bird, G.S.J.3    Putney, J.W.4
  • 59
    • 21344476293 scopus 로고
    • Sensitivity and uncertainty analysis of complex-models of disease transmission- an HIV model, as an example
    • Blower SM, Dowlatabadi H (1994) Sensitivity and uncertainty analysis of complex-models of disease transmission- an HIV model, as an example. In Stat Rev 62: 229-243.
    • (1994) Stat Rev , vol.62 , pp. 229-243
    • Blower, S.M.1    Dowlatabadi, H.2
  • 60
    • 45449094504 scopus 로고    scopus 로고
    • A methodology for performing global uncertainty and sensitivity analysis in systems biology
    • Marino S, Hogue IB, Ray CJ, Kirschner DE (2008) A methodology for performing global uncertainty and sensitivity analysis in systems biology. J Theor Biol 254: 178-196.
    • (2008) J Theor Biol , vol.254 , pp. 178-196
    • Marino, S.1    Hogue, I.B.2    Ray, C.J.3    Kirschner, D.E.4
  • 61
    • 0018468345 scopus 로고
    • Comparison of 3 methods for selecting values of input variables in the analysis of output from a computer code
    • McKay MD, Beckman RJ, Conover WJ (1979) Comparison of 3 methods for selecting values of input variables in the analysis of output from a computer code. Technometrics 21: 239-245.
    • (1979) Technometrics , vol.21 , pp. 239-245
    • McKay, M.D.1    Beckman, R.J.2    Conover, W.J.3
  • 62
    • 33846503153 scopus 로고    scopus 로고
    • Both ligand- and cell-specific parameters control ligand agonism in a kinetic model of G protein-coupled receptor signaling
    • Kinzer-Ursem TL, Linderman JJ (2007) Both ligand- and cell-specific parameters control ligand agonism in a kinetic model of G protein-coupled receptor signaling. PLoS Comput Biol 3(1): e6
    • (2007) PLoS Comput Biol , vol.3 , Issue.1
    • Kinzer-Ursem, T.L.1    Linderman, J.J.2


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