메뉴 건너뛰기




Volumn 97, Issue 3, 2009, Pages 722-729

Synchronization of pancreatic islet oscillations by intrapancreatic ganglia: A modeling study

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; MUSCARINIC AGENT;

EID: 68949090231     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2009.05.016     Document Type: Article
Times cited : (35)

References (64)
  • 2
    • 0036310201 scopus 로고    scopus 로고
    • Primary in vivo oscillations of metabolism in the pancreas
    • Bergsten, P., J. Westerlund, P. Liss, and P. O. Carlsson. 2002. Primary in vivo oscillations of metabolism in the pancreas. Diabetes. 51:699-703.
    • (2002) Diabetes , vol.51 , pp. 699-703
    • Bergsten, P.1    Westerlund, J.2    Liss, P.3    Carlsson, P.O.4
  • 3
    • 0029746149 scopus 로고    scopus 로고
    • Effects of glucose ingestion versus infusion on pulsatile insulin secretion: The incretin effect is achieved by amplification of insulin secretory burst mass
    • Porksen, N., S. Munn, J. Steers, J. D. Veldhuis, and P. C. Butler. 1996. Effects of glucose ingestion versus infusion on pulsatile insulin secretion: the incretin effect is achieved by amplification of insulin secretory burst mass. Diabetes. 45:1317-1323.
    • (1996) Diabetes , vol.45 , pp. 1317-1323
    • Porksen, N.1    Munn, S.2    Steers, J.3    Veldhuis, J.D.4    Butler, P.C.5
  • 4
    • 0034489574 scopus 로고    scopus 로고
    • Direct measurement of pulsatile insulin secretion from the portal vein in human subjects
    • Song, S. H., S. S. McIntyre, H. Shah, J. D. Veldhuis, P. C. Hayes, et al. 2000. Direct measurement of pulsatile insulin secretion from the portal vein in human subjects. J. Clin. Endocrinol. Metab. 85:4491-4499.
    • (2000) J. Clin. Endocrinol. Metab , vol.85 , pp. 4491-4499
    • Song, S.H.1    McIntyre, S.S.2    Shah, H.3    Veldhuis, J.D.4    Hayes, P.C.5
  • 5
    • 0019415621 scopus 로고
    • Brief, irregular oscillations of basal plasma insulin and glucose concentrations in diabetic man
    • Lang, D. A., D. R. Matthews, M. Burnet, and R. C. Turner. 1981. Brief, irregular oscillations of basal plasma insulin and glucose concentrations in diabetic man. Diabetes. 30:435-439.
    • (1981) Diabetes , vol.30 , pp. 435-439
    • Lang, D.A.1    Matthews, D.R.2    Burnet, M.3    Turner, R.C.4
  • 6
    • 0023951171 scopus 로고
    • Impaired pulsatile secretion of insulin in relatives of patients with non-insulin dependent diabetes
    • O'Rahilly, S., R. C. Turner, and D. R. Matthews. 1988. Impaired pulsatile secretion of insulin in relatives of patients with non-insulin dependent diabetes. N. Engl. J. Med. 318:1225-1230.
    • (1988) N. Engl. J. Med , vol.318 , pp. 1225-1230
    • O'Rahilly, S.1    Turner, R.C.2    Matthews, D.R.3
  • 7
    • 0030955017 scopus 로고    scopus 로고
    • Disorderly and nonstationary insulin secretion in relatives of patients with NIDDM
    • Schmitz, O., N. Pørksen, B. Nyholm, C. Skjærbæk, P. C. Butler, et al. 1997. Disorderly and nonstationary insulin secretion in relatives of patients with NIDDM. Am. J. Physiol. 272:E218-E226.
    • (1997) Am. J. Physiol , vol.272
    • Schmitz, O.1    Pørksen, N.2    Nyholm, B.3    Skjærbæk, C.4    Butler, P.C.5
  • 8
    • 0036360977 scopus 로고    scopus 로고
    • 2+ oscillations and pulsatile insulin secretion in islets from ob/ob mice
    • 2+ oscillations and pulsatile insulin secretion in islets from ob/ob mice. Diabetologia. 45:1154-1163.
    • (2002) Diabetologia , vol.45 , pp. 1154-1163
    • Ravier, M.A.1    Sehlin, J.2    Henquin, J.-C.3
  • 9
    • 0020791738 scopus 로고
    • Pulsatile insulin has greater hypoglycemic effect than continuous delivery
    • Matthews, D. R., B. A. Naylor, R. G. Jones, G. M. Ward, and R. C. Turner. 1983. Pulsatile insulin has greater hypoglycemic effect than continuous delivery. Diabetes. 32:617-621.
    • (1983) Diabetes , vol.32 , pp. 617-621
    • Matthews, D.R.1    Naylor, B.A.2    Jones, R.G.3    Ward, G.M.4    Turner, R.C.5
  • 10
    • 0022497629 scopus 로고
    • Efficacy of pulsatile versus continuous insulin administration on hepatic glucose production and glucose utilization in type I diabetic humans
    • Bratusch-Marrain, P. R., M. Komjati, and W. K. Waldhausl. 1986. Efficacy of pulsatile versus continuous insulin administration on hepatic glucose production and glucose utilization in type I diabetic humans. Diabetes. 35:922-926.
    • (1986) Diabetes , vol.35 , pp. 922-926
    • Bratusch-Marrain, P.R.1    Komjati, M.2    Waldhausl, W.K.3
  • 11
    • 0022641752 scopus 로고
    • Superior efficacy of pulsatile versus continuous hormone exposure on hepatic glucose production in vitro
    • Komjati, M., P. Bratusch-Marrain, and W. Waldhausl. 1986. Superior efficacy of pulsatile versus continuous hormone exposure on hepatic glucose production in vitro. Endocrinology. 118:312-319.
    • (1986) Endocrinology , vol.118 , pp. 312-319
    • Komjati, M.1    Bratusch-Marrain, P.2    Waldhausl, W.3
  • 12
    • 0025802673 scopus 로고
    • Pulsatile insulin delivery has greater metabolic effects than continuous hormone administration in man: Importance of pulse frequency
    • Paolisso, G., A. J. Scheen, D. Giugliano, S. Sgambato, A. Albert, et al. 1991. Pulsatile insulin delivery has greater metabolic effects than continuous hormone administration in man: importance of pulse frequency. J. Clin. Endocrinol. Metab. 72:607-615.
    • (1991) J. Clin. Endocrinol. Metab , vol.72 , pp. 607-615
    • Paolisso, G.1    Scheen, A.J.2    Giugliano, D.3    Sgambato, S.4    Albert, A.5
  • 13
    • 34247134694 scopus 로고    scopus 로고
    • The ins and outs of secretion from pancreatic β-cells: Control of single-vesicle exo- and endocytosis
    • MacDonald, P. E., and P. Rorsman. 2007. The ins and outs of secretion from pancreatic β-cells: control of single-vesicle exo- and endocytosis. Physiology (Bethesda). 22:113-121.
    • (2007) Physiology (Bethesda) , vol.22 , pp. 113-121
    • MacDonald, P.E.1    Rorsman, P.2
  • 14
    • 0020620416 scopus 로고
    • Isolated islets of Langerhans have slow oscillations of electrical activity
    • Cook, D. L. 1983. Isolated islets of Langerhans have slow oscillations of electrical activity. Metabolism. 32:681-685.
    • (1983) Metabolism , vol.32 , pp. 681-685
    • Cook, D.L.1
  • 16
    • 0037961599 scopus 로고    scopus 로고
    • 2+ dynamics of isolated mouse β-cells and islets: Implications for mathematical models
    • 2+ dynamics of isolated mouse β-cells and islets: implications for mathematical models. Biophys. J. 84:2852-2870.
    • (2003) Biophys. J , vol.84 , pp. 2852-2870
    • Zhang, M.1    Goforth, P.2    Sherman, A.3    Bertram, R.4    Satin, L.5
  • 17
    • 33644677761 scopus 로고    scopus 로고
    • Individual mice can be distinguished by the period of their islet calcium oscillations: Is there an intrinsic islet period that is imprinted in vivo?
    • Nunemaker, C. S., M. Zhang, D. H. Wasserman, O. P. McGuinness, A. C. Powers, et al. 2005. Individual mice can be distinguished by the period of their islet calcium oscillations: is there an intrinsic islet period that is imprinted in vivo? Diabetes. 54:3517-3522.
    • (2005) Diabetes , vol.54 , pp. 3517-3522
    • Nunemaker, C.S.1    Zhang, M.2    Wasserman, D.H.3    McGuinness, O.P.4    Powers, A.C.5
  • 19
    • 0011648510 scopus 로고    scopus 로고
    • The in vivo regulation of pulsatile insulin secretion
    • Pørksen, N. 2002. The in vivo regulation of pulsatile insulin secretion. Am. J. Physiol. 45:E3-E20.
    • (2002) Am. J. Physiol , vol.45
    • Pørksen, N.1
  • 20
    • 85031349858 scopus 로고    scopus 로고
    • Reference deleted in proof
    • Reference deleted in proof.
  • 21
    • 0030756468 scopus 로고    scopus 로고
    • Are metabolic oscillations responsible for normal oscillatory insulin secretion?
    • Tornheim, K. 1997. Are metabolic oscillations responsible for normal oscillatory insulin secretion? Diabetes. 46:1375-1380.
    • (1997) Diabetes , vol.46 , pp. 1375-1380
    • Tornheim, K.1
  • 22
    • 23244441271 scopus 로고    scopus 로고
    • Intra- and interislet synchronization of metabolically driven insulin secretion
    • Pedersen, M. G., R. Bertram, and A. Sherman. 2005. Intra- and interislet synchronization of metabolically driven insulin secretion. Biophys. J. 89:107-119.
    • (2005) Biophys. J , vol.89 , pp. 107-119
    • Pedersen, M.G.1    Bertram, R.2    Sherman, A.3
  • 23
    • 0018906755 scopus 로고
    • Sustained oscillations of insulin, glucagon, and somatostatin from the isolated canine pancreas during exposure to a constant glucose concentration
    • Stagner, J. I., E. Samols, and G. C. Weir. 1980. Sustained oscillations of insulin, glucagon, and somatostatin from the isolated canine pancreas during exposure to a constant glucose concentration. J. Clin. Invest. 65:939-942.
    • (1980) J. Clin. Invest , vol.65 , pp. 939-942
    • Stagner, J.I.1    Samols, E.2    Weir, G.C.3
  • 24
    • 0027989677 scopus 로고
    • Alterations in pulsatile insulin secretion in the Zucker diabetic fatty rat
    • Sturis, J., W. L. Pugh, J. Tang, D. M. Ostrega, J. S. Polonsky, et al. 1994. Alterations in pulsatile insulin secretion in the Zucker diabetic fatty rat. Am. J. Physiol. 267:E250-E259.
    • (1994) Am. J. Physiol , vol.267
    • Sturis, J.1    Pugh, W.L.2    Tang, J.3    Ostrega, D.M.4    Polonsky, J.S.5
  • 25
    • 0034001450 scopus 로고    scopus 로고
    • Autonomic regulation of islet hormone secretion - implications for health and disease
    • Ahren, B. 2000. Autonomic regulation of islet hormone secretion - implications for health and disease. Diabetologia. 43:393-410.
    • (2000) Diabetologia , vol.43 , pp. 393-410
    • Ahren, B.1
  • 26
    • 0022869282 scopus 로고
    • Neuropeptidergic versus cholinergic and adrenergic regulation of islet hormone secretion
    • Ahren, B., G. J. Taborsky, Jr., and D. Porte, Jr. 1986. Neuropeptidergic versus cholinergic and adrenergic regulation of islet hormone secretion. Diabetologia. 29:827-836.
    • (1986) Diabetologia , vol.29 , pp. 827-836
    • Ahren, B.1    Taborsky Jr., G.J.2    Porte Jr., D.3
  • 28
    • 0025278729 scopus 로고
    • Identification of vagal preganglionics that mediate cephalic phase insulin response
    • Berthoud, H. R., and T. L. Powley. 1990. Identification of vagal preganglionics that mediate cephalic phase insulin response. Am. J. Physiol. 258:R523-R530.
    • (1990) Am. J. Physiol , vol.258
    • Berthoud, H.R.1    Powley, T.L.2
  • 29
    • 0025425559 scopus 로고
    • Innervation of the pancreas by neurons in the gut
    • Kirchgessner, A. L., and M. D. Gershon. 1990. Innervation of the pancreas by neurons in the gut. J. Neurosci. 10:1626-1642.
    • (1990) J. Neurosci , vol.10 , pp. 1626-1642
    • Kirchgessner, A.L.1    Gershon, M.D.2
  • 30
    • 0000822864 scopus 로고
    • The innervation of pancreas of the rat, cat, and rabbit as revealed by the cholinesterase technique
    • Coupland, R. E. 1958. The innervation of pancreas of the rat, cat, and rabbit as revealed by the cholinesterase technique. J. Anat. 92:143-149.
    • (1958) J. Anat , vol.92 , pp. 143-149
    • Coupland, R.E.1
  • 31
    • 0024791928 scopus 로고
    • Intracellular recordings from pancreatic ganglia of the cat
    • King, B. F., J. A. Love, and J. H. Szurszewski. 1989. Intracellular recordings from pancreatic ganglia of the cat. J. Physiol. 419:379-403.
    • (1989) J. Physiol , vol.419 , pp. 379-403
    • King, B.F.1    Love, J.A.2    Szurszewski, J.H.3
  • 32
    • 0026429665 scopus 로고
    • Guinea pig pancreatic ganglia: Projections, transmitter content, and the type-specific localization of monoamine oxidase
    • Kirchgessner, A. L., and J. E. Pintar. 1991. Guinea pig pancreatic ganglia: projections, transmitter content, and the type-specific localization of monoamine oxidase. J. Comp. Neurol. 305:613-631.
    • (1991) J. Comp. Neurol , vol.305 , pp. 613-631
    • Kirchgessner, A.L.1    Pintar, J.E.2
  • 33
    • 0030790832 scopus 로고    scopus 로고
    • Distribution and ultrastructure of the autonomic nerves in the mouse pancreas
    • Ushiki, T., and S. Watanabe. 1997. Distribution and ultrastructure of the autonomic nerves in the mouse pancreas. Microsc. Res. Tech. 37:399-406.
    • (1997) Microsc. Res. Tech , vol.37 , pp. 399-406
    • Ushiki, T.1    Watanabe, S.2
  • 34
    • 0019393678 scopus 로고
    • Pancreatic endocrine responses to stimulation of the peripheral ends of the vagus nerves in conscious calves
    • Bloom, S. R., and A. V. Edwards. 1980. Pancreatic endocrine responses to stimulation of the peripheral ends of the vagus nerves in conscious calves. J. Physiol. 315:31-41.
    • (1980) J. Physiol , vol.315 , pp. 31-41
    • Bloom, S.R.1    Edwards, A.V.2
  • 35
    • 0022455497 scopus 로고
    • The mechanism of vagal nerve stimulation of glucagon and insulin secretion in the dog
    • Ahren, B., and G. J. Taborsky, Jr. 1986. The mechanism of vagal nerve stimulation of glucagon and insulin secretion in the dog. Endocrinology. 118:1551-1557.
    • (1986) Endocrinology , vol.118 , pp. 1551-1557
    • Ahren, B.1    Taborsky Jr., G.J.2
  • 36
    • 0023274082 scopus 로고
    • Vagal regulation of insulin, glucagon, and somatostatin secretion in vitro in the rat
    • Nishi, S., Y. Seino, H. Ishida, M. Seno, T. Taminato, et al. 1987. Vagal regulation of insulin, glucagon, and somatostatin secretion in vitro in the rat. J. Clin. Invest. 79:1191-1196.
    • (1987) J. Clin. Invest , vol.79 , pp. 1191-1196
    • Nishi, S.1    Seino, Y.2    Ishida, H.3    Seno, M.4    Taminato, T.5
  • 37
    • 0014250994 scopus 로고
    • A histochemical study of neuroinsular complexes in the pancreas of the rat
    • Morgan, C. R., and R. T. Lobl. 1968. A histochemical study of neuroinsular complexes in the pancreas of the rat. Anat. Rec. 160:231-237.
    • (1968) Anat. Rec , vol.160 , pp. 231-237
    • Morgan, C.R.1    Lobl, R.T.2
  • 38
    • 0035171313 scopus 로고    scopus 로고
    • Nerve cells associated with the endocrine pancreas in young mice: An ultrastructural analysis of the neuroinsular complex type I
    • Persson-Sjögren, S., A. Zashihin, and S. Forsgren. 2001. Nerve cells associated with the endocrine pancreas in young mice: an ultrastructural analysis of the neuroinsular complex type I. Histochem. J. 33:373-378.
    • (2001) Histochem. J , vol.33 , pp. 373-378
    • Persson-Sjögren, S.1    Zashihin, A.2    Forsgren, S.3
  • 39
    • 0023676354 scopus 로고
    • The muscarinic receptor subtype in mouse pancreatic β-cells
    • Henquin, J.-C., and M. Nenquin. 1988. The muscarinic receptor subtype in mouse pancreatic β-cells. FEBS Lett. 236:89-92.
    • (1988) FEBS Lett , vol.236 , pp. 89-92
    • Henquin, J.-C.1    Nenquin, M.2
  • 40
    • 0025213226 scopus 로고
    • Muscarinic receptor subtypes in rat pancreatic islets: Binding and functional studies
    • Verspohl, E. J., R. Tacke, E. Mutschler, and G. Lambrecht. 1990. Muscarinic receptor subtypes in rat pancreatic islets: binding and functional studies. Eur. J. Pharmacol. 178:303-311.
    • (1990) Eur. J. Pharmacol , vol.178 , pp. 303-311
    • Verspohl, E.J.1    Tacke, R.2    Mutschler, E.3    Lambrecht, G.4
  • 41
    • 0031417396 scopus 로고    scopus 로고
    • Guinea pig pancreatic neurons: Morphology, neurochemistry, electrical properties, and response to 5-HT
    • Liu, M., and A. L. Kirchgessner. 1997. Guinea pig pancreatic neurons: morphology, neurochemistry, electrical properties, and response to 5-HT. Am. J. Physiol. 273:G1273-G1289.
    • (1997) Am. J. Physiol , vol.273
    • Liu, M.1    Kirchgessner, A.L.2
  • 42
    • 0028338938 scopus 로고
    • Coordinate pulsatile insulin secretion by chronic intraportally transplanted islets in the isolated perfused rat liver
    • Pørksen, N., S. Munn, D. Ferguson, T. O'Brien, J. Veldhuis, et al. 1994. Coordinate pulsatile insulin secretion by chronic intraportally transplanted islets in the isolated perfused rat liver. J. Clin. Invest. 94: 219-227.
    • (1994) J. Clin. Invest , vol.94 , pp. 219-227
    • Pørksen, N.1    Munn, S.2    Ferguson, D.3    O'Brien, T.4    Veldhuis, J.5
  • 43
    • 10044256230 scopus 로고    scopus 로고
    • Calcium and glycolysis mediate multiple bursting modes in pancreatic islets
    • Bertram, R., L. Satin, M. Zhang, P. Smolen, and A. Sherman. 2004. Calcium and glycolysis mediate multiple bursting modes in pancreatic islets. Biophys. J. 87:3074-3087.
    • (2004) Biophys. J , vol.87 , pp. 3074-3087
    • Bertram, R.1    Satin, L.2    Zhang, M.3    Smolen, P.4    Sherman, A.5
  • 44
    • 33847772664 scopus 로고    scopus 로고
    • Interaction of glycolysis and mitochondrial respiration in metabolic oscillations of pancreatic islets
    • Bertram, R., L. S. Satin, M. G. Pedersen, D. S. Luciani, and A. Sherman. 2007. Interaction of glycolysis and mitochondrial respiration in metabolic oscillations of pancreatic islets. Biophys. J. 92:1544-1555.
    • (2007) Biophys. J , vol.92 , pp. 1544-1555
    • Bertram, R.1    Satin, L.S.2    Pedersen, M.G.3    Luciani, D.S.4    Sherman, A.5
  • 45
    • 0016254180 scopus 로고
    • The purine nucleotide cycle. IV. Interactions with oscillations of the glycolytic pathway in muscle extracts
    • Tornheim, K., and J. M. Lowenstein. 1974. The purine nucleotide cycle. IV. Interactions with oscillations of the glycolytic pathway in muscle extracts. J. Biol. Chem. 249:3241-3247.
    • (1974) J. Biol. Chem , vol.249 , pp. 3241-3247
    • Tornheim, K.1    Lowenstein, J.M.2
  • 47
    • 0030583177 scopus 로고    scopus 로고
    • Characterization of expression of phosphofructokinase isoforms in isolated rat pancreatic islets and purified β-cells and cloning and expression of the rat phosphofructokinase-A isoform
    • Ma, Z., S. Ramanadham, K. Kempe, Z. Hu, J. Ladenson, et al. 1996. Characterization of expression of phosphofructokinase isoforms in isolated rat pancreatic islets and purified β-cells and cloning and expression of the rat phosphofructokinase-A isoform. Biochim. Biophys. Acta. 1308:151-163.
    • (1996) Biochim. Biophys. Acta , vol.1308 , pp. 151-163
    • Ma, Z.1    Ramanadham, S.2    Kempe, K.3    Hu, Z.4    Ladenson, J.5
  • 48
    • 58149314256 scopus 로고    scopus 로고
    • Long lasting synchronization of calcium oscillations by cholinergic stimulation in isolated pancreatic islets
    • Zhang, M., B. Fendler, B. Peercy, P. Goel, R. Bertram, et al. 2008. Long lasting synchronization of calcium oscillations by cholinergic stimulation in isolated pancreatic islets. Biophys. J. 95:467-468.
    • (2008) Biophys. J , vol.95 , pp. 467-468
    • Zhang, M.1    Fendler, B.2    Peercy, B.3    Goel, P.4    Bertram, R.5
  • 50
    • 1942518752 scopus 로고    scopus 로고
    • Pancreatic β-cells communicate via intermittent release of ATP
    • Hellman, B., H. Dansk, and E. Grapengiesser. 2004. Pancreatic β-cells communicate via intermittent release of ATP. Am. J. Physiol. 286:E759-E765.
    • (2004) Am. J. Physiol , vol.286
    • Hellman, B.1    Dansk, H.2    Grapengiesser, E.3
  • 51
    • 0029031338 scopus 로고
    • A model for glycolytic oscillations based on skeletal muscle phosphofructokinase kinetics
    • Smolen, P. 1995. A model for glycolytic oscillations based on skeletal muscle phosphofructokinase kinetics. J. Theor. Biol. 174:137-148.
    • (1995) J. Theor. Biol , vol.174 , pp. 137-148
    • Smolen, P.1
  • 52
    • 0028178965 scopus 로고
    • i oscillations derived from a detailed kinetic model: A Hodgkin-Huxley like formalism
    • i oscillations derived from a detailed kinetic model: a Hodgkin-Huxley like formalism. J. Theor. Biol. 166:461-473.
    • (1994) J. Theor. Biol , vol.166 , pp. 461-473
    • Li, Y.-X.1    Rinzel, J.2
  • 53
    • 0021741559 scopus 로고
    • Glucose induces closure of single potassium channels in isolated rat pancreatic β-cells
    • Ashcroft, F. M., D. E. Harrison, and S. J. H. Ashcroft. 1984. Glucose induces closure of single potassium channels in isolated rat pancreatic β-cells. Nature. 312:446-448.
    • (1984) Nature , vol.312 , pp. 446-448
    • Ashcroft, F.M.1    Harrison, D.E.2    Ashcroft, S.J.H.3
  • 54
    • 0023754427 scopus 로고
    • + channels may control glucose-induced electrical activity in pancreatic β-cells
    • + channels may control glucose-induced electrical activity in pancreatic β-cells. Biochem. Biophys. Res. Commun. 156:769-775.
    • (1988) Biochem. Biophys. Res. Commun , vol.156 , pp. 769-775
    • Henquin, J.-C.1
  • 56
    • 20744449792 scopus 로고    scopus 로고
    • The design and implementation of FFTW3
    • Frigo, M., and S. G. Johnson. 2005. The design and implementation of FFTW3. Proc. IEEE. 93:216-231.
    • (2005) Proc. IEEE , vol.93 , pp. 216-231
    • Frigo, M.1    Johnson, S.G.2
  • 57
    • 0032999920 scopus 로고    scopus 로고
    • Glucose entrainment of high-frequency plasma insulin oscillations in control and type 2 diabetic subjects
    • Mao, C. S., N. Berman, K. Roberts, and E. Ipp. 1999. Glucose entrainment of high-frequency plasma insulin oscillations in control and type 2 diabetic subjects. Diabetes. 48:714-721.
    • (1999) Diabetes , vol.48 , pp. 714-721
    • Mao, C.S.1    Berman, N.2    Roberts, K.3    Ipp, E.4
  • 58
    • 0022065722 scopus 로고
    • Role of intrapancreatic ganglia in regulation of periodic insular secretions
    • Stagner, J. I., and E. Samols. 1985. Role of intrapancreatic ganglia in regulation of periodic insular secretions. Am. J. Physiol. 248:E522-E530.
    • (1985) Am. J. Physiol , vol.248
    • Stagner, J.I.1    Samols, E.2
  • 60
    • 0022067872 scopus 로고
    • Perturbation of insulin oscillations by nerve blockade in the in vitro canine pancreas
    • Stagner, J. I., and E. Samols. 1985. Perturbation of insulin oscillations by nerve blockade in the in vitro canine pancreas. Am. J. Physiol. 248:E516-E521.
    • (1985) Am. J. Physiol , vol.248
    • Stagner, J.I.1    Samols, E.2
  • 61
    • 0022545770 scopus 로고
    • Modulation of insulin secretion by pancreatic ganglionic nicotinic receptors
    • Stagner, J. I., and E. Samols. 1986. Modulation of insulin secretion by pancreatic ganglionic nicotinic receptors. Diabetes. 35:849-854.
    • (1986) Diabetes , vol.35 , pp. 849-854
    • Stagner, J.I.1    Samols, E.2
  • 62
    • 0034786750 scopus 로고    scopus 로고
    • Mechanisms and physiological significance of the cholinergic control of pancreatic β-cell function
    • Gilon, P., and J.-C. Henquin. 2001. Mechanisms and physiological significance of the cholinergic control of pancreatic β-cell function. Endocr. Rev. 22:565-604.
    • (2001) Endocr. Rev , vol.22 , pp. 565-604
    • Gilon, P.1    Henquin, J.-C.2
  • 63
    • 3242697081 scopus 로고    scopus 로고
    • 2+ oscillations in cell clusters prepared from single or multiple mouse pancreatic islets
    • 2+ oscillations in cell clusters prepared from single or multiple mouse pancreatic islets. Am. J. Physiol. 287:E340-E347.
    • (2004) Am. J. Physiol , vol.287
    • Zarkovic, M.1    Henquin, J.-C.2
  • 64
    • 21344449293 scopus 로고    scopus 로고
    • Inhibition of purinoceptors amplifies glucose-stimulated insulin release with removal of its pulsatility
    • Salehi, A., S. S. Quader, E. Grapengiesser, and B. Hellman. 2005. Inhibition of purinoceptors amplifies glucose-stimulated insulin release with removal of its pulsatility. Diabetes. 54:2126-2131.
    • (2005) Diabetes , vol.54 , pp. 2126-2131
    • Salehi, A.1    Quader, S.S.2    Grapengiesser, E.3    Hellman, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.