Alpha-2 adrenoceptor agonists and sepsis: Improved survival?

Critical Care

Volumn 14, Issue 4, 2010, Pages

  Quintin, Luc ^a  

^a UNIVERSITÉ DE LYON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CLONIDINE; DEXMEDETOMIDINE; DROTRECOGIN; FENTANYL; HYPERTENSIVE FACTOR; LORAZEPAM; OPIATE; SEDATIVE AGENT;

ANALGESIA; HUMAN; LETTER; LUNG VENTILATION; PRIORITY JOURNAL; RISK ASSESSMENT; SEPSIS; SURVIVAL RATE; SYSTOLIC BLOOD PRESSURE; MORTALITY; NOTE; SURVIVAL;

ADRENERGIC ALPHA-2 RECEPTOR AGONISTS; DEXMEDETOMIDINE; FENTANYL; HUMANS; SEPSIS; SURVIVAL ANALYSIS;

EID: 78651228701     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc9096     Document Type: Letter

References (9)

1. Pandharipande PP, Sanders RD, Girard TD, McGrane S, Thompson JL, Shintani AK, Herr DL, Maze M, Ely EW, Mends IT. Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial. Crit Care 2010, 14:R38. 2887145, 20233428, 10.1186/cc8916.
2. Gregorakos L, Kerezoudi E, Dimopoulos G, Thomaides T. Management of blood pressure instability in severe tetanus: the use of clonidine. Intensive Care Med 1997, 23:893-895. 10.1007/s001340050428, 9310809.
3. Pichot C, Mathern P, Khettab F, Ghignone M, Geloen A, Quintin L. Increased pressor response to noradrenaline during septic shock following clonidine?. Anesthesia Intensive Care (Sydney) 2010,
4. Venn RM, Newman PJ, Grounds RM. A phase II study to evaluate the efficacy of dexmedetomidine for sedation in the medical intensive care unit. Int Care Med 2003, 29:201-207.
5. Spies CD, Dubisz N, Neumann T, Blum S, Muller C, Rommelspacher H, Brummer G, Specht M, Sanft C, Hannemann L, Striebel HW, Schaff artzik W. Therapy of alcohol withdrawal syndrome in intensive care unit patients following trauma: results of a prospective, randomized trial. Crit Care Med 1996, 24:414-422. 10.1097/00003246-199603000-00009, 8625628.
6. Riker RR, Shehabi Y, Bokesch PM, Ceraso D, Wisemandle W, Koura F, Whitten P, Margolis BD, Byrne DW, Ely EW, Rocha MG. Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial. JAMA 2009, 301:489-499. 10.1001/jama.2009.56, 19188334.
7. Pandharipande PP, Pun BT, Herr DL, Maze M, Girard TD, Miller RR, Shintani AK, Thompson JL, Jackson JC, Deppen SA, Stiles RA, Dittus RS, Bernard GR, Ely EW. Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial. JAMA 2007, 298:2644-2653. 10.1001/jama.298.22.2644, 18073360.
8. Arain SR, Ruehlow RM, Uhrich TD, Ebert TJ. The efficacy of dexmedetomidine versus morphine for postoperative analgesia after major inpatient surgery. Anesth Analg 2004, 98:153-158. 10.1213/01.ANE.0000093225.39866.75, 14693611.
9. Venn RM, Grounds RM. Comparison between dexmedetomidine and propofol for sedation in the intensive care unit: patient and clinician perceptions. Br J Anaesth 2001, 87:684-690. 10.1093/bja/87.5.684, 11878517.