Increased pressor response to noradrenaline during septic shock following clonidine?

Anaesthesia and Intensive Care

Volumn 38, Issue 4, 2010, Pages 784-785

  Pichot, C ^a   Mathern, P ^a   Khettab, F ^a   Ghignone, M ^a   Geloen, A ^a   Quintin, L ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CLONIDINE; FUROSEMIDE; HYDROCORTISONE; NORADRENALIN; STEROID; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT;

ADULT RESPIRATORY DISTRESS SYNDROME; CHOLECYSTECTOMY; COLOSTOMY; DIURESIS; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG DOSE TITRATION; ECHOCARDIOGRAPHY; FEVER; HEART RATE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HYPOTENSION; IMMUNOCOMPROMISED PATIENT; INTENSIVE CARE UNIT; INTESTINE OBSTRUCTION; LETTER; LOW DRUG DOSE; LUNG LAVAGE; OLIGURIA; PRESSOR RESPONSE; PSEUDOMONAS AERUGINOSA; QUADRIPLEGIA; SEDATION; SEPTIC SHOCK; SINGLE DRUG DOSE; SYSTOLIC BLOOD PRESSURE; BLOOD PRESSURE; CASE REPORT; DRUG EFFECT; DRUG INTERACTION; MALE; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY;

ADRENERGIC ALPHA-AGONISTS; BLOOD PRESSURE; CLONIDINE; DRUG INTERACTIONS; HUMANS; MALE; MIDDLE AGED; NOREPINEPHRINE; SHOCK, SEPTIC;

EID: 77956626363     PISSN: 0310057X     EISSN: 14480271     Source Type: Journal    
DOI: None     Document Type: Letter

References (6)

1. Bellissant E, Annane D. Effect of hydrocortisone on phenylephrine - mean arterial pressure dose-response relationship in septic shock. Clin Pharmacol Ther 2000; 68:293-303.
2. Butler J, Kelly JG, O'Malley O, Pidgeon F. Beta-adrenoceptor adaptation to acute exercise. J Physiol 1983; 344:113-117.
3. Zoukos Y, Thomaides T, Pavitt DV, Leonard JP, Cuzner ML, Mathias CJ. Upregulation of beta adrenoceptors on circulating mononuclear cells after reduction of central sympathetic outflow by clonidine in normal subjects. Clin Auton Res 1992; 2:165-170.
4. Guthrie GP, Kotchen TA. Effects of oral clonidine on baroreflex function in patients with essential hypertension. Chest 1983; 83:S327-328.
5. Dollery CT, Harington M, Hodge JV. Haemodynamic studies with methyldopa: effect on cardiac output and response to pressor amines. Br Heart J 1963; 25:670-676.
6. Robertson D, Goldberg MR, Hollister AS, Wade D, Robertson RM. Clonidine raises blood pressure in severe idiopathic orthostatic hypotension. Am J Med 1983; 74:193-200 (Pubitemid 13192173)