Management of blood pressure instability in severe tetanus: The use of clonidine

Intensive Care Medicine

Volumn 23, Issue 8, 1997, Pages 893-895

  Gregorakos, L ^a   Kerezoudi, E ^b   Dimopoulos, G ^a   Thomaides, T ^c  

^a Chest Hospital of Athens   (Greece)

^b Polycliniki Hospital   (Greece)

^c Neurology Department   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CLONIDINE; DIAZEPAM; MUSCLE RELAXANT AGENT; SEDATIVE AGENT;

ADULT; AGED; ARTICLE; AUTONOMIC DYSFUNCTION; BLOOD PRESSURE REGULATION; CLINICAL ARTICLE; CLINICAL TRIAL; FEMALE; HUMAN; INTENSIVE CARE; INTRAVENOUS DRUG ADMINISTRATION; MALE; TETANUS;

ADRENERGIC ALPHA-AGONISTS; ADULT; AGED; AGED, 80 AND OVER; AUTONOMIC NERVOUS SYSTEM DISEASES; BLOOD PRESSURE; CLONIDINE; FEMALE; GREECE; HUMANS; MALE; MIDDLE AGED; STATISTICS, NONPARAMETRIC; SURVIVAL RATE; TETANUS;

EID: 0030869570     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001340050428     Document Type: Article

References (10)

1. Wright DK, Lalloo UG, Nayiagez S, Govender P (1989) Autonomic nervous system dysfunction in severe tetanus: current perspectives. Crit Care Med 17: 371-375
2. Buchanan N, Cane RD, Wolfson G, De Andrade M (1979) Autonomic dysfunction in tetanus. The effects of a variety of therapeutic agents with special reference to morphine. Intensive Care Med 5: 565-568
3. Edmudson RS, Flowers MW (1979) Intensive care in tetanus: management, complications and mortality in 100 cases. BMJ 1: 1401-1404
4. Wesley AG, Hariparsad D, Pather M, Rocke DA (1983) Labetalol in tetanus. Anaesthesia 38: 243-249
5. Sutton DN, Tremlett MR, Woodcock TE, Nielsen MS (1990) Management of autonomic dysfunction in severe tetanus: the use of magnesium sulphate and clonidine. Intensive Care Med 16: 75-80
6. Brown JL, Sinding H, Mathias CJ (1994) Autonomic disturbance in severe tetanus: failure of parenteral clonidine to control blood pressure. J Infect 29: 67-71
7. Kerr JH, Corbett JL, Prys-Roberts C, Crampton Smith A, Spalding JMK (1968) Involvement of the sympathetic nervous system in tetanus studies on 82 cases. Lancet II:236-241
8. Erdman G, Weigard H, Wellhoner HH (1975) Intraaxonal and extraaxonal transport of 125 I-tetanus toxin in early local tetanus. Naunyn Schmiedehergs Arch Pharmacol 290: 357
9. Bleck TP (1991) Tetanus. In: Scheid WM, Whitley RJ, Durack DT (eds) Infections of the central nervous system. Raven Press, New York, pp 603-624
10. 1-Imidazoline and alpha 2-adrenergic receptors in the antihypertensive responses evoked by central administration of clonidine agonists in conscious spontaneously hypertensive rats J Pharmacol Exp Ther 273: 1162-1171