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Volumn 23, Issue 2, 2011, Pages 158-167

Blocking Dopamine D2 Receptors by Haloperidol Curtails the Beneficial Impact of Calorie Restriction on the Metabolic Phenotype of High-Fat Diet Induced Obese Mice

Author keywords

Calorie restriction; Dopamine receptor D2; High fat diet; Insulin resistance; Mice

Indexed keywords

DOPAMINE 2 RECEPTOR; HALOPERIDOL; DOPAMINE RECEPTOR BLOCKING AGENT; INSULIN;

EID: 78651086857     PISSN: 09538194     EISSN: 13652826     Source Type: Journal    
DOI: 10.1111/j.1365-2826.2010.02092.x     Document Type: Article
Times cited : (15)

References (70)
  • 1
    • 0031549576 scopus 로고    scopus 로고
    • Seminars in medicine of the Beth Israel Deaconess Medical Center. Caloric intake and aging
    • Weindruch R, Sohal RS. Seminars in medicine of the Beth Israel Deaconess Medical Center. Caloric intake and aging. N Engl J Med 1997; 337: 986-994.
    • (1997) N Engl J Med , vol.337 , pp. 986-994
    • Weindruch, R.1    Sohal, R.S.2
  • 2
    • 0028787256 scopus 로고
    • Longevity, body weight, and neoplasia in ad libitum-fed and diet-restricted C57BL6 mice fed NIH-31 open formula diet
    • Blackwell BN, Bucci TJ, Hart RW, Turturro A. Longevity, body weight, and neoplasia in ad libitum-fed and diet-restricted C57BL6 mice fed NIH-31 open formula diet. Toxicol Pathol 1995; 23: 570-582.
    • (1995) Toxicol Pathol , vol.23 , pp. 570-582
    • Blackwell, B.N.1    Bucci, T.J.2    Hart, R.W.3    Turturro, A.4
  • 3
    • 0030746765 scopus 로고    scopus 로고
    • Calorie restriction induces a p53-independent delay of spontaneous carcinogenesis in p53-deficient and wild-type mice
    • Hursting SD, Perkins SN, Brown CC, Haines DC, Phang JM. Calorie restriction induces a p53-independent delay of spontaneous carcinogenesis in p53-deficient and wild-type mice. Cancer Res 1997; 57: 2843-2846.
    • (1997) Cancer Res , vol.57 , pp. 2843-2846
    • Hursting, S.D.1    Perkins, S.N.2    Brown, C.C.3    Haines, D.C.4    Phang, J.M.5
  • 4
    • 2342647592 scopus 로고    scopus 로고
    • Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans
    • Fontana L, Meyer TE, Klein S, Holloszy JO. Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans. Proc Natl Acad Sci USA 2004; 101: 6659-6663.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 6659-6663
    • Fontana, L.1    Meyer, T.E.2    Klein, S.3    Holloszy, J.O.4
  • 7
  • 8
    • 0033958461 scopus 로고    scopus 로고
    • Decrease in triglyceride accumulation in tissues by restricted diet and improvement of diabetes in Otsuka Long-Evans Tokushima fatty rats, a non-insulin-dependent diabetes model
    • Man ZW, Hirashima T, Mori S, Kawano K. Decrease in triglyceride accumulation in tissues by restricted diet and improvement of diabetes in Otsuka Long-Evans Tokushima fatty rats, a non-insulin-dependent diabetes model. Metabolism 2000; 49: 108-114.
    • (2000) Metabolism , vol.49 , pp. 108-114
    • Man, Z.W.1    Hirashima, T.2    Mori, S.3    Kawano, K.4
  • 9
    • 33749684748 scopus 로고    scopus 로고
    • Calorie restriction initiated at middle age improved glucose tolerance without affecting age-related impairments of insulin signaling in rat skeletal muscle
    • Park S, Komatsu T, Hayashi H, Yamaza H, Chiba T, Higami Y, Kuramoto K, Shimokawa I. Calorie restriction initiated at middle age improved glucose tolerance without affecting age-related impairments of insulin signaling in rat skeletal muscle. Exp Gerontol 2006; 41: 837-845.
    • (2006) Exp Gerontol , vol.41 , pp. 837-845
    • Park, S.1    Komatsu, T.2    Hayashi, H.3    Yamaza, H.4    Chiba, T.5    Higami, Y.6    Kuramoto, K.7    Shimokawa, I.8
  • 10
    • 0021242030 scopus 로고
    • Delayed loss of striatal dopamine receptors during aging of dietarily restricted rats
    • Roth GS, Ingram DK, Joseph JA. Delayed loss of striatal dopamine receptors during aging of dietarily restricted rats. Brain Res 1984; 300: 27-32.
    • (1984) Brain Res , vol.300 , pp. 27-32
    • Roth, G.S.1    Ingram, D.K.2    Joseph, J.A.3
  • 12
    • 34447303786 scopus 로고    scopus 로고
    • Effects of life-long caloric restriction and voluntary exercise on age-related changes in levels of catecholamine biosynthetic enzymes and angiotensin II receptors in the rat adrenal medulla and hypothalamus
    • Erdos B, Broxson CS, Landa T, Scarpace PJ, Leeuwenburgh C, Zhang Y, Tumer N. Effects of life-long caloric restriction and voluntary exercise on age-related changes in levels of catecholamine biosynthetic enzymes and angiotensin II receptors in the rat adrenal medulla and hypothalamus. Exp Gerontol 2007; 42: 745-752.
    • (2007) Exp Gerontol , vol.42 , pp. 745-752
    • Erdos, B.1    Broxson, C.S.2    Landa, T.3    Scarpace, P.J.4    Leeuwenburgh, C.5    Zhang, Y.6    Tumer, N.7
  • 13
    • 0038094515 scopus 로고    scopus 로고
    • Evidence of increased dopamine receptor signaling in food-restricted rats
    • Carr KD, Tsimberg Y, Berman Y, Yamamoto N. Evidence of increased dopamine receptor signaling in food-restricted rats. Neuroscience 2003; 119: 1157-1167.
    • (2003) Neuroscience , vol.119 , pp. 1157-1167
    • Carr, K.D.1    Tsimberg, Y.2    Berman, Y.3    Yamamoto, N.4
  • 14
    • 0029588435 scopus 로고
    • Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic
    • Zhou QY, Palmiter RD. Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic. Cell 1995; 83: 1197-1209.
    • (1995) Cell , vol.83 , pp. 1197-1209
    • Zhou, Q.Y.1    Palmiter, R.D.2
  • 16
    • 0030445765 scopus 로고    scopus 로고
    • Circadian rhythms regulate the expression of the thrifty genotype/phenotype
    • Meier AH, Cincotta AH. Circadian rhythms regulate the expression of the thrifty genotype/phenotype. Diabetes Rev 1996; 4: 464-487.
    • (1996) Diabetes Rev , vol.4 , pp. 464-487
    • Meier, A.H.1    Cincotta, A.H.2
  • 17
    • 0028600049 scopus 로고
    • Hard target: understanding dopaminergic neurotransmission
    • Nestler EJ. Hard target: understanding dopaminergic neurotransmission. Cell 1994; 79: 923-926.
    • (1994) Cell , vol.79 , pp. 923-926
    • Nestler, E.J.1
  • 18
    • 0029009779 scopus 로고
    • LHA dopaminergic activity in obese and lean Zucker rats
    • Yang ZJ, Meguid MM. LHA dopaminergic activity in obese and lean Zucker rats. Neuroreport 1995; 6: 1191-1194.
    • (1995) Neuroreport , vol.6 , pp. 1191-1194
    • Yang, Z.J.1    Meguid, M.M.2
  • 19
    • 0031684918 scopus 로고    scopus 로고
    • Combined effect of obesity and aging on feeding-induced monoamine release in the rostromedial hypothalamus of the Zucker rat
    • Lemierre S, Rouch C, Nicolaidis S, Orosco M. Combined effect of obesity and aging on feeding-induced monoamine release in the rostromedial hypothalamus of the Zucker rat. Int J Obes Relat Metab Disord 1998; 22: 993-999.
    • (1998) Int J Obes Relat Metab Disord , vol.22 , pp. 993-999
    • Lemierre, S.1    Rouch, C.2    Nicolaidis, S.3    Orosco, M.4
  • 20
    • 0029076922 scopus 로고
    • Spontaneous feeding-related monoamine changes in rostromedial hypothalamus of the obese Zucker rat: a microdialysis study
    • Orosco M, Rouch C, Meile MJ, Nicolaidis S. Spontaneous feeding-related monoamine changes in rostromedial hypothalamus of the obese Zucker rat: a microdialysis study. Physiol Behav 1995; 57: 1103-1106.
    • (1995) Physiol Behav , vol.57 , pp. 1103-1106
    • Orosco, M.1    Rouch, C.2    Meile, M.J.3    Nicolaidis, S.4
  • 21
    • 0242499401 scopus 로고    scopus 로고
    • Reduced dopaminergic tone in hypothalamic neural circuits: expression of a 'thrifty' genotype underlying the metabolic syndrome?
    • Pijl H. Reduced dopaminergic tone in hypothalamic neural circuits: expression of a 'thrifty' genotype underlying the metabolic syndrome? Eur J Pharmacol 2003; 480: 125-131.
    • (2003) Eur J Pharmacol , vol.480 , pp. 125-131
    • Pijl, H.1
  • 22
    • 0036785545 scopus 로고    scopus 로고
    • Expression of dopaminergic receptors in the hypothalamus of lean and obese Zucker rats and food intake
    • Fetissov SO, Meguid MM, Sato T, Zhang LH. Expression of dopaminergic receptors in the hypothalamus of lean and obese Zucker rats and food intake. Am J Physiol Regul Integr Comp Physiol 2002; 283: R905-R910.
    • (2002) Am J Physiol Regul Integr Comp Physiol , vol.283
    • Fetissov, S.O.1    Meguid, M.M.2    Sato, T.3    Zhang, L.H.4
  • 24
    • 0037032660 scopus 로고    scopus 로고
    • Comparative effects of the antipsychotics sulpiride or risperidone in rats. I: bodyweight, food intake, body composition, hormones and glucose tolerance
    • Baptista T, Araujo dB, Ying Kin NM, Beaulieu S, Walker D, Joober R, Lalonde J, Richard D. Comparative effects of the antipsychotics sulpiride or risperidone in rats. I: bodyweight, food intake, body composition, hormones and glucose tolerance. Brain Res 2002; 957: 144-151.
    • (2002) Brain Res , vol.957 , pp. 144-151
    • Baptista, T.1    Araujo, dB.2    Ying Kin, N.M.3    Beaulieu, S.4    Walker, D.5    Joober, R.6    Lalonde, J.7    Richard, D.8
  • 25
    • 0023269179 scopus 로고
    • Long term administration of some antipsychotic drugs increases body weight and feeding in rats. Are D2 dopamine receptors involved?
    • Baptista T, Parada M, Hernandez L. Long term administration of some antipsychotic drugs increases body weight and feeding in rats. Are D2 dopamine receptors involved? Pharmacol Biochem Behav 1987; 27: 399-405.
    • (1987) Pharmacol Biochem Behav , vol.27 , pp. 399-405
    • Baptista, T.1    Parada, M.2    Hernandez, L.3
  • 26
    • 18744366088 scopus 로고    scopus 로고
    • Second-generation (atypical) antipsychotics and metabolic effects: a comprehensive literature review
    • Newcomer JW. Second-generation (atypical) antipsychotics and metabolic effects: a comprehensive literature review. CNS Drugs 2005; 19(Suppl 1): 1-93.
    • (2005) CNS Drugs , vol.19 , Issue.SUPPL. 1 , pp. 1-93
    • Newcomer, J.W.1
  • 27
    • 14644415476 scopus 로고    scopus 로고
    • Metabolic dysregulation with atypical antipsychotics occurs in the absence of underlying disease: a placebo-controlled study of olanzapine and risperidone in dogs
    • Ader M, Kim SP, Catalano KJ, Ionut V, Hucking K, Richey JM, Kabir M, Bergman RN. Metabolic dysregulation with atypical antipsychotics occurs in the absence of underlying disease: a placebo-controlled study of olanzapine and risperidone in dogs. Diabetes 2005; 54: 862-871.
    • (2005) Diabetes , vol.54 , pp. 862-871
    • Ader, M.1    Kim, S.P.2    Catalano, K.J.3    Ionut, V.4    Hucking, K.5    Richey, J.M.6    Kabir, M.7    Bergman, R.N.8
  • 30
    • 0033048184 scopus 로고    scopus 로고
    • Intracerebroventricular administration of bromocriptine ameliorates the insulin-resistant/glucose-intolerant state in hamsters
    • Luo S, Liang Y, Cincotta AH. Intracerebroventricular administration of bromocriptine ameliorates the insulin-resistant/glucose-intolerant state in hamsters. Neuroendocrinology 1999; 69: 160-166.
    • (1999) Neuroendocrinology , vol.69 , pp. 160-166
    • Luo, S.1    Liang, Y.2    Cincotta, A.H.3
  • 31
    • 0035991892 scopus 로고    scopus 로고
    • Co-administration of dopamine D1 and D2 agonists additively decreases daily food intake, body weight and hypothalamic neuropeptide Y level in rats
    • Kuo DY. Co-administration of dopamine D1 and D2 agonists additively decreases daily food intake, body weight and hypothalamic neuropeptide Y level in rats. J Biomed Sci 2002; 9: 126-132.
    • (2002) J Biomed Sci , vol.9 , pp. 126-132
    • Kuo, D.Y.1
  • 32
    • 0034917841 scopus 로고    scopus 로고
    • Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review
    • Geyer MA, Krebs-Thomson K, Braff DL, Swerdlow NR. Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review. Psychopharmacology (Berl) 2001; 156: 117-154.
    • (2001) Psychopharmacology (Berl) , vol.156 , pp. 117-154
    • Geyer, M.A.1    Krebs-Thomson, K.2    Braff, D.L.3    Swerdlow, N.R.4
  • 34
    • 0035514162 scopus 로고    scopus 로고
    • In muscle-specific lipoprotein lipase-overexpressing mice, muscle triglyceride content is increased without inhibition of insulin-stimulated whole-body and muscle-specific glucose uptake
    • Voshol PJ, Jong MC, Dahlmans VE, Kratky D, Levak-Frank S, Zechner R, Romijn JA, Havekes LM. In muscle-specific lipoprotein lipase-overexpressing mice, muscle triglyceride content is increased without inhibition of insulin-stimulated whole-body and muscle-specific glucose uptake. Diabetes 2001; 50: 2585-2590.
    • (2001) Diabetes , vol.50 , pp. 2585-2590
    • Voshol, P.J.1    Jong, M.C.2    Dahlmans, V.E.3    Kratky, D.4    Levak-Frank, S.5    Zechner, R.6    Romijn, J.A.7    Havekes, L.M.8
  • 35
    • 0004209977 scopus 로고    scopus 로고
    • The Mouse Brain in Stereotaxic Coordinates
    • San Diego, CA: Academic Press,
    • Paxinos G, Franklin KBJ. The Mouse Brain in Stereotaxic Coordinates. San Diego, CA: Academic Press, 2001.
    • (2001)
    • Paxinos, G.1    Franklin, K.B.J.2
  • 37
    • 0000567961 scopus 로고    scopus 로고
    • Caloric restriction reverses hepatic insulin resistance in aging rats by decreasing visceral fat
    • Barzilai N, Banerjee S, Hawkins M, Chen W, Rossetti L. Caloric restriction reverses hepatic insulin resistance in aging rats by decreasing visceral fat. J Clin Invest 1998; 101: 1353-1361.
    • (1998) J Clin Invest , vol.101 , pp. 1353-1361
    • Barzilai, N.1    Banerjee, S.2    Hawkins, M.3    Chen, W.4    Rossetti, L.5
  • 38
    • 0028942913 scopus 로고
    • Is caloric restriction effective in preventing diabetes mellitus in the Otsuka Long Evans Tokushima fatty rat, a model of spontaneous non-insulin-dependent diabetes mellitus?
    • Okauchi N, Mizuno A, Yoshimoto S, Zhu M, Sano T, Shima K. Is caloric restriction effective in preventing diabetes mellitus in the Otsuka Long Evans Tokushima fatty rat, a model of spontaneous non-insulin-dependent diabetes mellitus? Diabetes Res Clin Pract 1995; 27: 97-106.
    • (1995) Diabetes Res Clin Pract , vol.27 , pp. 97-106
    • Okauchi, N.1    Mizuno, A.2    Yoshimoto, S.3    Zhu, M.4    Sano, T.5    Shima, K.6
  • 39
    • 71949096402 scopus 로고    scopus 로고
    • Improved insulin sensitivity by calorie restriction is associated with reduction of ERK and p70S6K activities in the liver of obese Zucker rats
    • Zheng Y, Zhang W, Pendleton E, Leng S, Wu J, Chen R, Sun XJ. Improved insulin sensitivity by calorie restriction is associated with reduction of ERK and p70S6K activities in the liver of obese Zucker rats. J Endocrinol 2009; 203: 337-347.
    • (2009) J Endocrinol , vol.203 , pp. 337-347
    • Zheng, Y.1    Zhang, W.2    Pendleton, E.3    Leng, S.4    Wu, J.5    Chen, R.6    Sun, X.J.7
  • 40
    • 0038623652 scopus 로고    scopus 로고
    • Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake
    • Anson RM, Guo Z, de Cabo R, Iyun T, Rios M, Hagepanos A, Ingram DK, Lane MA, Mattson MP. Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake. Proc Natl Acad Sci USA 2003; 100: 6216-6220.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 6216-6220
    • Anson, R.M.1    Guo, Z.2    de Cabo, R.3    Iyun, T.4    Rios, M.5    Hagepanos, A.6    Ingram, D.K.7    Lane, M.A.8    Mattson, M.P.9
  • 41
    • 19444375435 scopus 로고    scopus 로고
    • Two days of a very low calorie diet reduces endogenous glucose production in obese type 2 diabetic patients despite the withdrawal of blood glucose-lowering therapies including insulin
    • Jazet IM, Pijl H, Frolich M, Romijn JA, Meinders AE. Two days of a very low calorie diet reduces endogenous glucose production in obese type 2 diabetic patients despite the withdrawal of blood glucose-lowering therapies including insulin. Metabolism 2005; 54: 705-712.
    • (2005) Metabolism , vol.54 , pp. 705-712
    • Jazet, I.M.1    Pijl, H.2    Frolich, M.3    Romijn, J.A.4    Meinders, A.E.5
  • 43
    • 0031824622 scopus 로고    scopus 로고
    • Bromocriptine/SKF38393 ameliorates islet dysfunction in the diabetic (db/db) mouse
    • Liang Y, Jetton TL, Lubkin M, Meier AH, Cincotta AH. Bromocriptine/SKF38393 ameliorates islet dysfunction in the diabetic (db/db) mouse. Cell Mol Life Sci 1998; 54: 703-711.
    • (1998) Cell Mol Life Sci , vol.54 , pp. 703-711
    • Liang, Y.1    Jetton, T.L.2    Lubkin, M.3    Meier, A.H.4    Cincotta, A.H.5
  • 44
    • 0035655521 scopus 로고    scopus 로고
    • Systemic treatment with sympatholytic dopamine agonists improves aberrant beta-cell hyperplasia and GLUT2, glucokinase, and insulin immunoreactive levels in ob/ob mice
    • Jetton TL, Liang Y, Cincotta AH. Systemic treatment with sympatholytic dopamine agonists improves aberrant beta-cell hyperplasia and GLUT2, glucokinase, and insulin immunoreactive levels in ob/ob mice. Metabolism 2001; 50: 1377-1384.
    • (2001) Metabolism , vol.50 , pp. 1377-1384
    • Jetton, T.L.1    Liang, Y.2    Cincotta, A.H.3
  • 46
    • 33744964843 scopus 로고    scopus 로고
    • Effects of typical and atypical antipsychotics on glucose-insulin homeostasis and lipid metabolism in first-episode schizophrenia
    • Wu RR, Zhao JP, Liu ZN, Zhai JG, Guo XF, Guo WB, Tang JS. Effects of typical and atypical antipsychotics on glucose-insulin homeostasis and lipid metabolism in first-episode schizophrenia. Psychopharmacology (Berl) 2006; 186: 572-578.
    • (2006) Psychopharmacology (Berl) , vol.186 , pp. 572-578
    • Wu, R.R.1    Zhao, J.P.2    Liu, Z.N.3    Zhai, J.G.4    Guo, X.F.5    Guo, W.B.6    Tang, J.S.7
  • 48
    • 34548362074 scopus 로고    scopus 로고
    • Hypothalamic leptin regulation of energy homeostasis and glucose metabolism
    • Morton GJ. Hypothalamic leptin regulation of energy homeostasis and glucose metabolism. J Physiol 2007; 583: 437-443.
    • (2007) J Physiol , vol.583 , pp. 437-443
    • Morton, G.J.1
  • 49
    • 69349089612 scopus 로고    scopus 로고
    • Aripiprazole differentially affects mesolimbic and nigrostriatal dopaminergic transmission: implications for long-term drug efficacy and low extrapyramidal side-effects
    • Han M, Huang XF, Deng C. Aripiprazole differentially affects mesolimbic and nigrostriatal dopaminergic transmission: implications for long-term drug efficacy and low extrapyramidal side-effects. Int J Neuropsychopharmacol 2009; 12: 941-952.
    • (2009) Int J Neuropsychopharmacol , vol.12 , pp. 941-952
    • Han, M.1    Huang, X.F.2    Deng, C.3
  • 50
    • 33644554848 scopus 로고    scopus 로고
    • Antipsychotic-induced alterations in D2 dopamine receptor interacting proteins within the cortex
    • Kabbani N, Levenson R. Antipsychotic-induced alterations in D2 dopamine receptor interacting proteins within the cortex. Neuroreport 2006; 17: 299-301.
    • (2006) Neuroreport , vol.17 , pp. 299-301
    • Kabbani, N.1    Levenson, R.2
  • 51
    • 0029853502 scopus 로고    scopus 로고
    • Effect of chronic treatment with typical and atypical neuroleptics on the expression of dopamine D2 and D3 receptors in rat brain
    • Hurley MJ, Stubbs CM, Jenner P, Marsden CD. Effect of chronic treatment with typical and atypical neuroleptics on the expression of dopamine D2 and D3 receptors in rat brain. Psychopharmacology (Berl) 1996; 128: 362-370.
    • (1996) Psychopharmacology (Berl) , vol.128 , pp. 362-370
    • Hurley, M.J.1    Stubbs, C.M.2    Jenner, P.3    Marsden, C.D.4
  • 52
    • 55649115291 scopus 로고    scopus 로고
    • Atypical antipsychotic drugs induce derangements in glucose homeostasis by acutely increasing glucagon secretion and hepatic glucose output in the rat
    • Smith GC, Chaussade C, Vickers M, Jensen J, Shepherd PR. Atypical antipsychotic drugs induce derangements in glucose homeostasis by acutely increasing glucagon secretion and hepatic glucose output in the rat. Diabetologia 2008; 51: 2309-2317.
    • (2008) Diabetologia , vol.51 , pp. 2309-2317
    • Smith, G.C.1    Chaussade, C.2    Vickers, M.3    Jensen, J.4    Shepherd, P.R.5
  • 55
    • 0034000298 scopus 로고    scopus 로고
    • Predicting how equipotent doses of chlorpromazine, haloperidol, sulpiride, raclopride and clozapine reduce locomotor activity in mice
    • Simon VM, Parra A, Minarro J, Arenas MC, Vinader-Caerols C, Aguilar MA. Predicting how equipotent doses of chlorpromazine, haloperidol, sulpiride, raclopride and clozapine reduce locomotor activity in mice. Eur Neuropsychopharmacol 2000; 10: 159-164.
    • (2000) Eur Neuropsychopharmacol , vol.10 , pp. 159-164
    • Simon, V.M.1    Parra, A.2    Minarro, J.3    Arenas, M.C.4    Vinader-Caerols, C.5    Aguilar, M.A.6
  • 56
    • 54349089567 scopus 로고    scopus 로고
    • Evaluation of age and sex differences in locomotion and catalepsy during repeated administration of haloperidol and clozapine in adolescent and adult rats
    • Wiley JL, Evans RL. Evaluation of age and sex differences in locomotion and catalepsy during repeated administration of haloperidol and clozapine in adolescent and adult rats. Pharmacol Res 2008; 58: 240-246.
    • (2008) Pharmacol Res , vol.58 , pp. 240-246
    • Wiley, J.L.1    Evans, R.L.2
  • 57
    • 79952702945 scopus 로고    scopus 로고
    • Olanzapine promotes fat accumulation in male rats by decreasing physical activity, repartitioning energy and increasing adipose tissue lipogenesis while impairing lipolysis
    • ; doi:10.1038/mp.2010.33
    • Albaugh VL, Judson JG, She P, Lang CH, Maresca KP, Joyal JL, Lynch CJ. Olanzapine promotes fat accumulation in male rats by decreasing physical activity, repartitioning energy and increasing adipose tissue lipogenesis while impairing lipolysis. Mol Psychiatry 2010; doi:10.1038/mp.2010.33.
    • (2010) Mol Psychiatry
    • Albaugh, V.L.1    Judson, J.G.2    She, P.3    Lang, C.H.4    Maresca, K.P.5    Joyal, J.L.6    Lynch, C.J.7
  • 59
    • 73249129989 scopus 로고    scopus 로고
    • Impact of 9 days of bed rest on hepatic and peripheral insulin action, insulin secretion, and whole-body lipolysis in healthy young male offspring of patients with type 2 diabetes
    • Alibegovic AC, Hojbjerre L, Sonne MP, van Hall G, Stallknecht B, Dela F, Vaag A. Impact of 9 days of bed rest on hepatic and peripheral insulin action, insulin secretion, and whole-body lipolysis in healthy young male offspring of patients with type 2 diabetes. Diabetes 2009; 58: 2749-2756.
    • (2009) Diabetes , vol.58 , pp. 2749-2756
    • Alibegovic, A.C.1    Hojbjerre, L.2    Sonne, M.P.3    van Hall, G.4    Stallknecht, B.5    Dela, F.6    Vaag, A.7
  • 60
    • 77950575039 scopus 로고    scopus 로고
    • Effect of 10 days of bedrest on metabolic and vascular insulin action: a study in individuals at risk for type 2 diabetes
    • Sonne MP, Alibegovic AC, Hojbjerre L, Vaag A, Stallknecht B, Dela F. Effect of 10 days of bedrest on metabolic and vascular insulin action: a study in individuals at risk for type 2 diabetes. J Appl Physiol 2010; 108: 830-837.
    • (2010) J Appl Physiol , vol.108 , pp. 830-837
    • Sonne, M.P.1    Alibegovic, A.C.2    Hojbjerre, L.3    Vaag, A.4    Stallknecht, B.5    Dela, F.6
  • 62
    • 0028124472 scopus 로고
    • Effect of detraining on GLUT-4 protein in human skeletal muscle
    • McCoy M, Proietto J, Hargreves M. Effect of detraining on GLUT-4 protein in human skeletal muscle. J Appl Physiol 1994; 77: 1532-1536.
    • (1994) J Appl Physiol , vol.77 , pp. 1532-1536
    • McCoy, M.1    Proietto, J.2    Hargreves, M.3
  • 63
    • 0022875855 scopus 로고
    • Modulatory role for prolactin in the elevation of striatal dopamine receptor density induced by chronic treatment with dopamine receptor antagonists
    • Hruska RE. Modulatory role for prolactin in the elevation of striatal dopamine receptor density induced by chronic treatment with dopamine receptor antagonists. Brain Res Bull 1986; 16: 331-339.
    • (1986) Brain Res Bull , vol.16 , pp. 331-339
    • Hruska, R.E.1
  • 64
    • 0037036057 scopus 로고    scopus 로고
    • The effects of dopamine and D2 receptor antagonists on pituitary hormone secretion are intact in mice lacking dopamine D2L receptor
    • Xu R, Parlow AF, Wang Y. The effects of dopamine and D2 receptor antagonists on pituitary hormone secretion are intact in mice lacking dopamine D2L receptor. Brain Res 2002; 939: 95-99.
    • (2002) Brain Res , vol.939 , pp. 95-99
    • Xu, R.1    Parlow, A.F.2    Wang, Y.3
  • 65
    • 0018961538 scopus 로고
    • Correlation of hyperprolactinemia with altered plasma insulin and glucagon: similarity to effects of late human pregnancy
    • Gustafson AB, Banasiak MF, Kalkhoff RK, Hagen TC, Kim HJ. Correlation of hyperprolactinemia with altered plasma insulin and glucagon: similarity to effects of late human pregnancy. J Clin Endocrinol Metab 1980; 51: 242-246.
    • (1980) J Clin Endocrinol Metab , vol.51 , pp. 242-246
    • Gustafson, A.B.1    Banasiak, M.F.2    Kalkhoff, R.K.3    Hagen, T.C.4    Kim, H.J.5
  • 66
    • 70350294653 scopus 로고    scopus 로고
    • Evaluation of insulin sensitivity in hyperprolactinemic subjects by euglycemic hyperinsulinemic clamp technique
    • Tuzcu A, Yalaki S, Arikan S, Gokalp D, Bahcec M, Tuzcu S. Evaluation of insulin sensitivity in hyperprolactinemic subjects by euglycemic hyperinsulinemic clamp technique. Pituitary 2009; 12: 330-334.
    • (2009) Pituitary , vol.12 , pp. 330-334
    • Tuzcu, A.1    Yalaki, S.2    Arikan, S.3    Gokalp, D.4    Bahcec, M.5    Tuzcu, S.6
  • 67
    • 33846264544 scopus 로고    scopus 로고
    • Acute effects of atypical antipsychotics on whole-body insulin resistance in rats: implications for adverse metabolic effects
    • Houseknecht KL, Robertson AS, Zavadoski W, Gibbs EM, Johnson DE, Rollema H. Acute effects of atypical antipsychotics on whole-body insulin resistance in rats: implications for adverse metabolic effects. Neuropsychopharmacology 2007; 32: 289-297.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 289-297
    • Houseknecht, K.L.1    Robertson, A.S.2    Zavadoski, W.3    Gibbs, E.M.4    Johnson, D.E.5    Rollema, H.6
  • 69


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.