Atypical antipsychotic drugs induce derangements in glucose homeostasis by acutely increasing glucagon secretion and hepatic glucose output in the rat

Diabetologia

Volumn 51, Issue 12, 2008, Pages 2309-2317

  Smith, G C ^a   Chaussade, C ^a   Vickers, M ^b   Jensen, J ^c   Shepherd, P R ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c NATIONAL INSTITUTE OF OCCUPATIONAL HEALTH   (Norway)

Author keywords

Clozapine; Glucagon; Gluconeogenesis; Hepatic glucose production; Schizophrenia; Type 2 diabetes

Indexed keywords

ATYPICAL ANTIPSYCHOTIC AGENT; CLOZAPINE; GLUCAGON; GLUCOSE; GLYCEROL; HALOPERIDOL; PROTEIN KINASE B; PYRUVIC ACID; QUETIAPINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; GLUCAGON RELEASE; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; INSULIN RELEASE; INSULIN RESISTANCE; MALE; NONHUMAN; OBESITY; PRIORITY JOURNAL; RAT; WEIGHT GAIN;

ANIMALS; ANTIPSYCHOTIC AGENTS; BODY COMPOSITION; BODY WEIGHT; CELL LINE; ENZYME ACTIVATION; FEEDING BEHAVIOR; GLUCAGON; GLUCOSE; HOMEOSTASIS; LIVER; MALE; MICE; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 55649115291     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-008-1152-3     Document Type: Article

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