Protective effect of Spirulina against 4-nitroquinoline-1-oxide induced toxicity

Molecular Biology Reports

Volumn 38, Issue 1, 2011, Pages 309-317

  Viswanadha, Vijaya Padma ^a   Sivan, Siddharth ^b   Rajendra Shenoi, Roopesh ^a  

^a BHARATHIAR UNIVERSITY   (India)

^b KONGUNADU ARTS AND SCIENCE COLLEGE   (India)

Author keywords

4NQO; Antioxidants; Hepatic markers; Lipid peroxidation; Renal markers; Spirulina

Indexed keywords

4 NITROQUINOLINE 1 OXIDE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CATALASE; CREATININE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; LACTATE DEHYDROGENASE; SPIRULINA EXTRACT; SUPEROXIDE DISMUTASE; UREA; URIC ACID;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG DETERMINATION; DRUG ISOLATION; ENZYME LOCALIZATION; LACTATE DEHYDROGENASE BLOOD LEVEL; LIPID PEROXIDATION; LIVER PROTECTION; LIVER TOXICITY; MALE; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; RAT; RENAL PROTECTION; SPIRULINA; TISSUE DISTRIBUTION; UREA BLOOD LEVEL; URIC ACID BLOOD LEVEL;

4-NITROQUINOLINE-1-OXIDE; ANIMALS; BIOLOGICAL MARKERS; CATALASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; KIDNEY; LIVER; MALE; PROTECTIVE AGENTS; RATS; RATS, WISTAR; SPIRULINA; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

ANIMALIA; RATTUS; SPIRULINA;

EID: 78651060872     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-010-0109-z     Document Type: Article

References (67)

1. H Endo T Ono T Sugimura 1971 Chemistry and biological action of 4-nitroquinoline-1-oxide Recent Results Cancer Res 34 17 30
2. J McCann NE Spingarn J Kobori BN Ames 1975 Detection of carcinogen as mutagens: bacterial tester strains with R factor plasmids Proc Natl Acad Sci USA 72 979 983 1:CAS:528:DyaE2MXkt1ejsbs%3D 10.1073/pnas.72.3.979 165497
3. M Kitano 2000 Host genes controlling the susceptibility and resistance to squamous cell carcinoma of the tongue in a rat model Pathol Int 50 353 362 1:CAS:528:DC%2BD3cXlsF2htbs%3D 10.1046/j.1440-1827.2000.01058.x 10849324 (Pubitemid 30451478)
4. M Nagao T Sugimura 1976 Molecular biology of the carcinogen, 4-nitroquinoline 1-oxide Adv Cancer Res 23 131 169 1:CAS:528:DyaE28XltVOjtb0%3D 10.1016/S0065-230X(08)60545-X 818888
5. M Tada 1975 Seryl-tRNA synthetase and activation of the carcinogen 4-nitroquinoline-1-oxide Nature 255 510 512 1:CAS:528:DyaE2MXlsFyrtLw%3D 10.1038/255510a0 166317
6. K Kohdab Y Kawazoe Y Minoura M Tada 1991 Separation and identification of N4-(guanosine-7-yl)-4-aminoquinoline-1-oxide, a novel nucleic acid adduct of carcinogen 4-nitroquinoline 1-oxide Carcinogenesis 12 1523 1525 10.1093/carcin/12.8.1523
7. Y Arima C Nishigori T Takeuchi S Oka K Morimoto A Utani Y Miyachi 2006 4-Nitroquinoline-1-oxide forms 8-hydroxydeoxyguanosine in human fibroblasts through reactive oxygen species Toxicol Sci 91 2 382 392 1:CAS:528: DC%2BD28XkvVSkurw%3D 10.1093/toxsci/kfj161 16547075 (Pubitemid 43827291)
8. Collin G, Höke H (2005) "Quinoline and isoquinoline" Ullmann's encyclopedia of chemical technology. Wiley-VCH, Weinheim. doi: 10.1002/14356007.a22-465
9. T Tanaka 1995 Chemoprevention of oral carcinogenesis Eur J Cancer 31 3 15
10. T Sugimura M Nagao Y Okada 1966 Carcinogenic action of N-methyl-N-nitro-N-nitrosoguanidine Nature 210 962 963 1:CAS:528: DyaF28Xktlejsb8%3D 10.1038/210962b0 5960331
11. H Yoshimura S Yoshihara N Koga K Nagata I Wada J Kuroki Y Hokama 1985 Inductive effect on hepatic enzymes and toxicity of congeners of PCBs and PCDFs Environ Health Perspect 59 113 119 1:CAS:528:DyaL2MXkvVartb0%3D 10.2307/3429883 3921354
12. R Doll 1992 The lessons of life: keynote address to the nutrition and cancer conference Cancer Res 52 2024s 2029s 1:STN:280:DyaK387otlWjtg%3D%3D 1311987
13. AE Rogers SH Zeisel J Groopman 1993 Diet and carcinogenesis Carcinogenesis 14 2205 2217 1:CAS:528:DyaK2cXltlCksg%3D%3D 10.1093/carcin/14.11. 2205 8242845 (Pubitemid 23335172)
14. N Verma M Vinayak 2008 Antioxidant action of Andrographis paniculata on lymphoma Mol Biol Rep 35 535 540 1:CAS:528:DC%2BD1cXhsVKjtrjN 10.1007/s11033-007-9119-x 17805989
15. B Ganesan S Buddhan R Anandan R Sivakumar R AnbinEzhilan 2010 Antioxidant defense of betaine against isoprenaline-induced myocardial infarction in rats Mol Biol Rep 37 1319 1327 1:CAS:528:DC%2BC3cXhtlajtbs%3D 10.1007/s11033-009- 9508-4 19288277
16. N Verma M Vinayak 2009 Effect of Terminalia arjuna on antioxidant defense system in cancer Mol Biol Rep 36 159 164 1:CAS:528:DC%2BD1cXhtl2mu73F 10.1007/s11033-008-9279-3 18537039
17. SH Oh SC Lima 2006 A rapid and transient ROS generation by cadmium triggers apoptosis via caspase-dependent pathway in HepG2 cells and this is inhibited through N-acetylcysteine mediated catalase upregulation Toxicol Appl Pharmacol 212 212 223 1:CAS:528:DC%2BD28XktVGiurY%3D 10.1016/j.taap.2005.07.018 16169029
18. 2+-ATPase activities: protection by l-cysteine Basic Clin Pharmacol Toxicol 94 112 118 1:CAS:528:DC%2BD2cXis1alt7c%3D 10.1111/j.1742-7843.2004. pto940303.x 15049340
19. B Liu W Li Y Li Z Wang H Li P Liu J Fu 2009 Protective effects of N-acetylcysteine in isoproterenol-induced myocardium injury in rats Mol Biol Rep 36 761 765 10.1007/s11033-008-9241-4 18389381
20. CV Seshadri BV Umesh R Manoharan 1991 B-carotene studies in Spirulina Bioresour Technol 38 111 113 1:CAS:528:DyaK38XitFehu78%3D 10.1016/0960-8524(91) 90140-F
21. MS Miranda RG Cintra SB Barros J Mancini Filho 1998 Antioxidant activity of the microalga Spirulina maxima Braz J Med Biol Res 31 1075 1079 1:CAS:528:DyaK1cXlvFyhu7w%3D 10.1590/S0100-879X1998000800007 9777014
22. A Mittal PV Kumar S Banerjee AR Rao A Kumar 1999 Modulatory potential of Spirulina fusiforms on carcinogen metabolizing enzymes in Swiss albino mice Phytother Res 13 111 114 1:STN:280:DyaK1M3gs1Wrsg%3D%3D 10.1002/(SICI)1099- 1573(199903)13:2<111::AID-PTR386>3.0.CO;2-2 10190182 (Pubitemid 29129442)
23. K Hayashi T Hayashi I Kojima 1996 A natural sulphated polysaccharide, calcium Spirulin isolated from Spirulina plantensis: in vitro and ex vivo evaluation of antiherpes simplex virus and antihuman immunodeficiency virus activities AIDS Res Hum Retroviruses 12 15 1463 1471 1:CAS:528: DyaK28XmsFOksL4%3D 10.1089/aid.1996.12.1463 8893054
24. S Ayehunie A Belay TW Baba RM Ruprecht 1998 Inhibition of HIV-1 replication by an aqueous extract of Spirulina platensis (Arthrospira platensis) J AIDS Hum Retrovirol 18 7 12 1:STN:280:DyaK1c3lsVartg%3D%3D
25. MA Qureshi JD Garlich MT Kidd 1996 Dietary Spirulina platensis enhances humoral and cell-mediated immune functions in chickens Immunopharmacol Immunotoxicol 18 465 476 1:STN:280:DyaK2s%2Fis1eiug%3D%3D 10.3109/ 08923979609052748 8872497
26. MK Sharma A Sharma A Kumar M Kumar 2007 Spirulina fusiformis provides protection against mercury chloride induced oxidative stress in Swiss albino mice Food Chem Toxicol 45 2412 2419 1:CAS:528:DC%2BD2sXht1ahsrfP 10.1016/j.fct.2007.06.023 17706852 (Pubitemid 47600450)
27. M Rasool EP Sabina B Lavanya 2006 Anti-inflammatory effect of Spirulina fusiforms on adjuvant-induced arthritis in mice Biol Pharm Bull 29 1 2483 2487 1:CAS:528:DC%2BD2sXpsVOhtw%3D%3D 10.1248/bpb.29.2483 17142986 (Pubitemid 44885873)
28. Y Takai Y Hossayamada T Kato 1991 Effect of water soluble and water insoluble fractions of Spirulina over serum lipids and glucose resistance of rats J Jpn Soc Nutr Food Sci 44 273 277
29. A Ramamoorthy S Premakumari 1996 Effect of supplementation of Spirulina on hypercholesterolemic patients J Food Sci Technol 33 124 128
30. B Mathew R Sankaranarayanan P Nair C Varghese T Somanathan P Amma 1995 Evaluation of chemo prevention of oral cancer with Spirulina fusiformis Nutr Cancer 24 197 202 1:STN:280:DyaK287hslaluw%3D%3D 10.1080/01635589509514407 8584455
31. J Schwartz RF Troxler BG Saffer 1987 Algae-derived phycocyanin is both cytostatic and cytotoxic to oral squamous cell carcinoma (human or hamster) J Dent Res 66 160 164
32. H Fukino Y Takagi Y Yamane 1990 Effect of Spirulina (S. platensis) on the renal toxicity induced by inorganic mercury and cisplatin Eisei Kagaku 36 5 9
33. Z Zhi-gang L Zhi-li L Xue-xian 1997 Study on the isolation, purification and antioxidation properties of polysaccharides from Spirulina maxima Acta Bot Sin 39 77 81
34. EP Sabina J Samuel S RajappaRamya S Patel N Mandal P Pranatharthiiharan PP Mishra MK Rasool 2009 Hepatoprotective and antioxidant potential of Spirulina fusiformis on acetaminophen-induced hepatotoxicity in mice IJIB 6 1 1 5 1:CAS:528:DC%2BD1MXmvVClsbw%3D
35. S Reitman SA Frankel 1959 Colorimetric method for determination of serum glutamate oxalo acetate and glutamic pyruvic transaminases Am J Clin Pathol 28 56 63
36. Nieland A (1955) Lactic acid dehydrogenase of heart muscle. In: Methods in Enzymology, vol 1. Academic Press, New York, pp 394
37. WG Nichans D Samuelson 1968 Formation of malondialdehyde from phospholipid arachidonate during microsomal lipid peroxidation Eur J Biochem 6 26 30
38. K Moore LJ Roberts 1998 Measurement of lipid peroxidation Free Radic Res 28 6 659 671 1:CAS:528:DyaK1cXlvFegtbo%3D 10.3109/10715769809065821 9736317
39. P Kakkar B Das PN Viswanathan 1984 A modified spectrophotometric assay of superoxide dismutase Ind J Biochem Biophys 21 130 132 1:CAS:528: DyaL2cXksFSmsL0%3D
40. KA Sinha 1972 Colorimetric assay of catalase Ann Biochem 47 389 394 1:CAS:528:DyaE38XktVahsLo%3D 10.1016/0003-2697(72)90132-7
41. JT Rotruck AL Pope HE Ganther AB Swanson 1984 Selenium biochemical roles as a component of glutathione peroxidase Science 179 588 590 10.1126/science.179.4073.588
42. WR Habig MJ Pbst WB Jakpoly 1974 Glutathione transferase A first enzymatic step in mercaturic acid formation J Biol Chem 249 7130 7139 1:CAS:528:DyaE2MXltlahtg%3D%3D 4436300
43. GL Ellman 1959 Tissue sulfhydryl groups Arch Biochem Biophys 82 7077 10.1016/0003-9861(59)90090-6
44. S Natelson ML Scott N Vessac 1951 Rapid method for the estimation of urea in biological fluid by means of reaction between diacetyl and urea Am J Clin Pathol 21 275 278 1:CAS:528:DyaG3MXisVCmug%3D%3D 14818981
45. J Broad JH Sirota 1948 Clearance of endogenous creatine in man J Clin Investig 27 645 654 10.1172/JCI102012
46. Caraway WT (1963) In: Seligson D (ed) Standard methods of clinical chemistry. Academic Press, New York, pp 239-247
47. OH Lowry MJ Roesborough AL Farr RJ Randall 1951 Protein measurement with folin-phenol reagent J Biol Chem 193 265 275 1:CAS:528:DyaG38XhsVyrsw%3D%3D 14907713
48. TP Devasagayam JC Tilak KK Boloor KS Sane SS Ghaskadbi RD Lele 2004 Free radicals and antioxidants in human health: current status and future prospects J Assoc Physicians India 52 794 804 1:STN:280:DC%2BD2M3msl2iuw%3D%3D 15909857
49. AR Collins 2005 Antioxidant intervention as a route to cancer prevention Eur J Cancer 41 13 1923 1930 1:CAS:528:DC%2BD2MXpslyitrY%3D 10.1016/j.ejca.2005. 06.004 16111883 (Pubitemid 41557678)
50. W Nakahara 1961 Critique of carcinogenic mechanism Prog Exp Tumor Res 2 158 202 1:STN:280:DyaF38%2FnvFGqtA%3D%3D 14478105
51. W Nakahara F Fukuoka T Sugimura 1957 Carcinogenic action of 4-nitroquinoline A oxide Gann 48 129 137 1:STN:280:DyaG1c%2Fhs1ygsw%3D%3D
52. M Tada M Tada 1976 Main binding sites of the carcinogen, 4-nitroquinoline-1-oxide in nucleic acids Biochem Biophys Acta 454 558 566 1:CAS:528:DyaE2sXjvVCisQ%3D%3D 826278
53. M Tada K Kohda Y Kawazoe 1984 Biomimetic preparation and structure determination of QGI, one of the quinoline-DNA base adducts formed in cells treated with 4-nitroquinoline-1-oxide Gann 75 976 985 1:CAS:528: DyaL2MXntlyksQ%3D%3D 6097493
54. M Ishizawa H Endo 1967 On the mode of action of a potent carcinogen. 4-Hydroxylamino quinoline-1-oxide on bacteriophage T4 Biochem Pharmacol 16 637 646 1:CAS:528:DyaF2sXhtFeis78%3D 10.1016/0006-2952(67)90075-5 6033784
55. T Sugimura H Otake T Matsushima 1968 Single strand scissions of DNA caused by a carcinogen, 4-hydroxylamino-quinoline-l-oxide Nature (Lond) 218 392 393 1:CAS:528:DyaF1cXktVWgtL8%3D 10.1038/218392a0
56. M Hozumi 1969 Production of hydrogen peroxide by 4- hydroxylaminoquinoline-l-oxide Gann 60 83 90 1:CAS:528:DyaF1MXpsV2isw%3D%3D 5781978
57. T Nunoshiba B Demple 1993 Potent intracellular oxidative stress exerted by the carcinogen 4-nitroquinoline-N-oxide Cancer Res 53 3250 3252 1:CAS:528:DyaK3sXlsFersLg%3D 8391920
58. S Balasenthil CR Ramachandran S Nagini 2001 Prevention of 4-nitroquinoline-1-oxide-induced rat tongue carcinogenesis by garlic Fitoterapia 72 5 524 531 1:CAS:528:DC%2BD3MXks1Okurc%3D 10.1016/S0367-326X(01)00262-3 11429247 (Pubitemid 32594804)
59. Henrikson R (1989) Earth food Spirulina. Cited from Recolina Ltd. Renore Enterprises Inc, Launa Beach, California, pp 27-65
60. VB Bhat KM Madyastha 2000 C-phycocyanin: a potent peroxyl radical scavenger in vivo and in vitro Biochem Biophys Res Commun 275 20 25 1:CAS:528:DC%2BD3cXls1Cnt7c%3D 10.1006/bbrc.2000.3270 10944434 (Pubitemid 30663622)
61. P Viitala IJ Newhouse 2004 Vitamin E supplementation, exercise and lipid peroxidation in human participants Eur J Appl Physiol 93 1-2 108 115 1:CAS:528:DC%2BD2cXptlygsbo%3D 10.1007/s00421-004-1178-2 15248069 (Pubitemid 39485586)
62. MA Qureshi RA Ali 1996 Spirulina platensis exposure enhances macrophage phagocytic function in cats Immunopharmacol Immunotoxicol 18 457 463 1:STN:280:DyaK2s%2Fis1eitQ%3D%3D 10.3109/08923979609052747 8872496
63. S Karthikeyan 2004 Hepatotoxicity of isoniazid: a study on the activity of marker enzymes of liver toxicity in serum and liver tissue of rabbits Indian J Pharmacol 36 4 247 249 1:CAS:528:DC%2BD2cXns1Sjtbc%3D
64. LB Seeff BA Cuccherini HJ Zimmerman 1986 Acetaminophen hepatotoxicity in alcoholics: a therapeutic misadventure Ann Intern Med 104 3 399 404 1:STN:280:DyaL287ivVKlsg%3D%3D 3511825
65. BB Vadiraja NW Gaikwad KM Madyastha 1998 Hepatoprotective effect of C-phycocyanin: protection for carbon tetrachloride and R-(+)-pulegone-mediated hepatotoxicity in rats Biochem Biophys Res Commun 249 428 431 1:CAS:528:DyaK1cXls12gtb0%3D 10.1006/bbrc.1998.9149 9712713 (Pubitemid 28431770)
66. A Amin AA Hamza S Daoud W Hamza 2006 Spirulina protects against cadmium-induced hepatotoxicity in rats Am J Pharmacol Toxicol 1 2 21 25 10.3844/ajptsp.2006.21.25
67. SM Farooq D Asokan R Sakthivel P Kalaiselvi P Varalakshmi 2004 Salubrious effect of C-phycocyanin against oxalate mediated renal cell injury Clin Chim Acta 348 199 205 1:CAS:528:DC%2BD2cXnsFSktrs%3D 10.1016/j.cccn.2004.05.016 15369755 (Pubitemid 39209020)