메뉴 건너뛰기




Volumn 155, Issue 1, 2011, Pages 282-292

Biosynthesis of the cyanogenic glucosides linamarin and lotaustralin in cassava: Isolation, biochemical characterization, and expression pattern of cyp71e7, the oxime-metabolizing cytochrome P450 enzyme

Author keywords

[No Author keywords available]

Indexed keywords

MANIHOT ESCULENTA; SORGHUM BICOLOR;

EID: 78650993977     PISSN: 00320889     EISSN: 15322548     Source Type: Journal    
DOI: 10.1104/pp.110.164053     Document Type: Article
Times cited : (75)

References (59)
  • 1
    • 0034695491 scopus 로고    scopus 로고
    • Cytochromes P-450 from cassava (Manihot esculenta Crantz) catalyzing the first steps in the biosynthesis of the cyanogenic glucosides linamarin and lotaustralin: Cloning, functional expression in Pichia pastoris, and substrate specificity of the isolated recombinant enzymes
    • Andersen MD, Busk PK, Svendsen I, Møller BL (2000) Cytochromes P-450 from cassava (Manihot esculenta Crantz) catalyzing the first steps in the biosynthesis of the cyanogenic glucosides linamarin and lotaustralin: cloning, functional expression in Pichia pastoris, and substrate specificity of the isolated recombinant enzymes. J Biol Chem 275: 1966-1975
    • (2000) J Biol Chem , vol.275 , pp. 1966-1975
    • Andersen, M.D.1    Busk, P.K.2    Svendsen, I.3    Møller, B.L.4
  • 2
    • 0034824595 scopus 로고    scopus 로고
    • The involvement of two P450 enzymes, CYP83B1 and CYP83A1, in auxin homeostasis and glucosinolate biosynthesis
    • Bak S, Feyereisen R (2001) The involvement of two P450 enzymes, CYP83B1 and CYP83A1, in auxin homeostasis and glucosinolate biosynthesis. Plant Physiol 127: 108-118
    • (2001) Plant Physiol , vol.127 , pp. 108-118
    • Bak, S.1    Feyereisen, R.2
  • 3
    • 0032005917 scopus 로고    scopus 로고
    • Cloning of three A-type cytochromes P450, CYP71E1, CYP98, and CYP99 from Sorghum bicolor (L.) Moench by a PCR approach and identification by expression in Escherichia coli of CYP71E1 as a multifunctional cytochrome P450 in the biosynthesis of the cyanogenic glucoside dhurrin
    • Bak S, Kahn RA, Nielsen HL, Møller BL, Halkier BA (1998) Cloning of three A-type cytochromes P450, CYP71E1, CYP98, and CYP99 from Sorghum bicolor (L.) Moench by a PCR approach and identification by expression in Escherichia coli of CYP71E1 as a multifunctional cytochrome P450 in the biosynthesis of the cyanogenic glucoside dhurrin. Plant Mol Biol 36: 393-405
    • (1998) Plant Mol Biol , vol.36 , pp. 393-405
    • Bak, S.1    Kahn, R.A.2    Nielsen, H.L.3    Møller, B.L.4    Halkier, B.A.5
  • 4
    • 0033367009 scopus 로고    scopus 로고
    • Metabolic engineering of p-hydroxybenzylglucosinolate in Arabidopsis by expression of the cyanogenic CYP79A1 from Sorghum bicolor
    • Bak S, Olsen CE, Petersen BL, Møller BL, Halkier BA (1999) Metabolic engineering of p-hydroxybenzylglucosinolate in Arabidopsis by expression of the cyanogenic CYP79A1 from Sorghum bicolor. Plant J 20: 663-671
    • (1999) Plant J , vol.20 , pp. 663-671
    • Bak, S.1    Olsen, C.E.2    Petersen, B.L.3    Møller, B.L.4    Halkier, B.A.5
  • 6
    • 0035108851 scopus 로고    scopus 로고
    • CYP83B1, a cytochrome P450 at the metabolic branch point in auxin and indole glucosinolate biosynthesis in Arabidopsis
    • Bak S, Tax FE, Feldmann KA, Galbraith DW, Feyereisen R (2001) CYP83B1, a cytochrome P450 at the metabolic branch point in auxin and indole glucosinolate biosynthesis in Arabidopsis. Plant Cell 13: 101-111
    • (2001) Plant Cell , vol.13 , pp. 101-111
    • Bak, S.1    Tax, F.E.2    Feldmann, K.A.3    Galbraith, D.W.4    Feyereisen, R.5
  • 7
    • 0031455842 scopus 로고    scopus 로고
    • Geographical and seasonal association between linamarin and cyanide exposure from cassava and the upper motor neurone disease konzo in former Zaire
    • Banea-Mayambu JP, Tylleskär T, Gitebo N, Matadi N, Gebre-Medhin M, Rosling H (1997) Geographical and seasonal association between linamarin and cyanide exposure from cassava and the upper motor neurone disease konzo in former Zaire. TropMed Int Health 2: 1143-1151
    • (1997) TropMed Int Health , vol.2 , pp. 1143-1151
    • Banea-Mayambu, J.P.1    Tylleskär, T.2    Gitebo, N.3    Matadi, N.4    Gebre-Medhin, M.5    Rosling, H.6
  • 8
    • 0001384282 scopus 로고
    • Distribution of cyanogenic potential in cassava germplasm
    • In M Bokanga, AJA Essers, N Poulter, H Rosling, O Tewe, eds, WOCAS, Ibadan, Nigeria
    • Bokanga M (1994) Distribution of cyanogenic potential in cassava germplasm. In M Bokanga, AJA Essers, N Poulter, H Rosling, O Tewe, eds, International Workshop on Cassava Safety. WOCAS, Ibadan, Nigeria, pp 117-123
    • (1994) International Workshop on Cassava Safety , pp. 117-123
    • Bokanga, M.1
  • 9
    • 0028240839 scopus 로고
    • Dehydration of alkyl- and arylaldoximes as a new cytochrome P450-catalyzed reaction: Mechanism and stereochemical characteristics
    • Boucher JL, Delaforge M, Mansuy D (1994) Dehydration of alkyl- and arylaldoximes as a new cytochrome P450-catalyzed reaction: mechanism and stereochemical characteristics. Biochemistry 33: 7811-7818
    • (1994) Biochemistry , vol.33 , pp. 7811-7818
    • Boucher, J.L.1    Delaforge, M.2    Mansuy, D.3
  • 11
    • 0031570338 scopus 로고    scopus 로고
    • Characterization of linamarase of latex and its localization in petioles in cassava
    • Elias M, Nambisan B, Sudhakaran PR (1997) Characterization of linamarase of latex and its localization in petioles in cassava. Arch Biochem Biophys 341: 222-228
    • (1997) Arch Biochem Biophys , vol.341 , pp. 222-228
    • Elias, M.1    Nambisan, B.2    Sudhakaran, P.R.3
  • 12
    • 2442689485 scopus 로고    scopus 로고
    • Biosynthesis of the nitrile glucosides rhodiocyanoside A and D and the cyanogenic glucosides lotaustralin and linamarin in Lotus japonicus
    • Forslund K, Morant M, Jørgensen B, Olsen CE, Asamizu E, Sato S, Tabata S, Bak S (2004) Biosynthesis of the nitrile glucosides rhodiocyanoside A and D and the cyanogenic glucosides lotaustralin and linamarin in Lotus japonicus. Plant Physiol 135: 71-84
    • (2004) Plant Physiol , vol.135 , pp. 71-84
    • Forslund, K.1    Morant, M.2    Jørgensen, B.3    Olsen, C.E.4    Asamizu, E.5    Sato, S.6    Tabata, S.7    Bak, S.8
  • 14
    • 38249018984 scopus 로고
    • Formation of sulfatoglucosides from exogenous aldoximes in plant-cell cultures and organs
    • Grootwassink JWD, Balsevich JJ, Kolenovsky AD (1990) Formation of sulfatoglucosides from exogenous aldoximes in plant-cell cultures and organs. Plant Sci 66: 11-20
    • (1990) Plant Sci , vol.66 , pp. 11-20
    • Grootwassink, J.W.D.1    Balsevich, J.J.2    Kolenovsky, A.D.3
  • 15
    • 12044256272 scopus 로고
    • Involvement of cytochrome P-450 in the biosynthesis of dhurrin in Sorghum bicolor (L.) Moench
    • Halkier BA, Møller BL (1991) Involvement of cytochrome P-450 in the biosynthesis of dhurrin in Sorghum bicolor (L.) Moench. Plant Physiol 96: 10-17
    • (1991) Plant Physiol , vol.96 , pp. 10-17
    • Halkier, B.A.1    Møller, B.L.2
  • 16
    • 0029153022 scopus 로고
    • Purification and characterization of recombinant cytochrome P450TYR expressed at high levels in Escherichia coli
    • Halkier BA, Nielsen HL, Koch B, Møller BL (1995) Purification and characterization of recombinant cytochrome P450TYR expressed at high levels in Escherichia coli. Arch Biochem Biophys 322: 369-377
    • (1995) Arch Biochem Biophys , vol.322 , pp. 369-377
    • Halkier, B.A.1    Nielsen, H.L.2    Koch, B.3    Møller, B.L.4
  • 17
    • 0024351594 scopus 로고
    • The biosynthesis of cyanogenic glucosides in higher plants: The (E)- and (Z)-isomers of p-hydroxyphenylacetaldehyde oxime as intermediates in the biosynthesis of dhurrin in Sorghum bicolor (L.) Moench
    • Halkier BA, Olsen CE, Møller BL (1989) The biosynthesis of cyanogenic glucosides in higher plants: the (E)- and (Z)-isomers of p-hydroxyphenylacetaldehyde oxime as intermediates in the biosynthesis of dhurrin in Sorghum bicolor (L.) Moench. J Biol Chem 264: 19487-19494
    • (1989) J Biol Chem , vol.264 , pp. 19487-19494
    • Halkier, B.A.1    Olsen, C.E.2    Møller, B.L.3
  • 19
    • 0032501390 scopus 로고    scopus 로고
    • New catalytic properties of iron porphyrins: Model systems for cytochrome P450- catalyzed dehydration of aldoximes
    • Hart-Davis J, Battioni P, Boucher JL, Mansuy D (1998) New catalytic properties of iron porphyrins: model systems for cytochrome P450- catalyzed dehydration of aldoximes. J Am Chem Soc 120: 12524-12530
    • (1998) J Am Chem Soc , vol.120 , pp. 12524-12530
    • Hart-Davis, J.1    Battioni, P.2    Boucher, J.L.3    Mansuy, D.4
  • 20
    • 0037256698 scopus 로고    scopus 로고
    • The Arabidopsis ref2 mutant is defective in the gene encoding CYP83A1 and shows both phenylpropanoid and glucosinolate phenotypes
    • Hemm MR, Ruegger MO, Chapple C (2003) The Arabidopsis ref2 mutant is defective in the gene encoding CYP83A1 and shows both phenylpropanoid and glucosinolate phenotypes. Plant Cell 15: 179-194
    • (2003) Plant Cell , vol.15 , pp. 179-194
    • Hemm, M.R.1    Ruegger, M.O.2    Chapple, C.3
  • 21
    • 0017794351 scopus 로고
    • Substrate and inhibitor binding to cytochrome P450 by optical difference spectroscopy
    • Jefcoate CR (1978) Substrate and inhibitor binding to cytochrome P450 by optical difference spectroscopy. Methods Enzymol 27: 258-279
    • (1978) Methods Enzymol , vol.27 , pp. 258-279
    • Jefcoate, C.R.1
  • 22
    • 73649131594 scopus 로고    scopus 로고
    • Plant NADPH-cytochrome P450 oxidoreductases
    • Jensen K, Møller BL (2010) Plant NADPH-cytochrome P450 oxidoreductases. Phytochemistry 71: 132-141
    • (2010) Phytochemistry , vol.71 , pp. 132-141
    • Jensen, K.1    Møller, B.L.2
  • 23
    • 0031985773 scopus 로고    scopus 로고
    • Why are so many food plants cyanogenic?
    • Jones DA (1998) Why are so many food plants cyanogenic? Phytochemistry 47: 155-162
    • (1998) Phytochemistry , vol.47 , pp. 155-162
    • Jones, D.A.1
  • 24
    • 77957813628 scopus 로고    scopus 로고
    • The biosynthesis, degradation, transport and possible function of cyanogenic glucosides
    • In JT Romeo, R Ibrahim, LVarin, V De Luca, eds, Elsevier Science, New York
    • Jones PR, Andersen MD, Nielsen JS, Høj PB, Møller BL (2000) The biosynthesis, degradation, transport and possible function of cyanogenic glucosides. In JT Romeo, R Ibrahim, LVarin, V De Luca, eds, Evolution of Metabolic Pathways. Elsevier Science, New York, pp 191-247
    • (2000) Evolution of Metabolic Pathways , pp. 191-247
    • Jones, P.R.1    Andersen, M.D.2    Nielsen, J.S.3    Høj, P.B.4    Møller, B.L.5
  • 25
    • 0033544872 scopus 로고    scopus 로고
    • The UDP-glucose:P-hydroxymandelonitrile- O-glucosyltransferase that catalyzes the last step in synthesis of the cyanogenic glucoside dhurrin in Sorghum bicolor: Isolation, cloning, heterologous expression, and substrate specificity
    • Jones PR, Møller BL, Høj PB (1999) The UDP-glucose:p-hydroxymandelonitrile- O-glucosyltransferase that catalyzes the last step in synthesis of the cyanogenic glucoside dhurrin in Sorghum bicolor: isolation, cloning, heterologous expression, and substrate specificity. J Biol Chem 274: 35483-35491
    • (1999) J Biol Chem , vol.274 , pp. 35483-35491
    • Jones, P.R.1    Møller, B.L.2    Høj, P.B.3
  • 26
    • 33644803873 scopus 로고    scopus 로고
    • Cassava plants with a depleted cyanogenic glucoside content in leaves and tubers: Distribution of cyanogenic glucosides, their site of synthesis and transport, and blockage of the biosynthesis by RNA interference technology
    • Jørgensen K, Bak S, Busk PK, Sørensen C, Olsen CE, Puonti-Kaerlas J, Møller BL (2005a) Cassava plants with a depleted cyanogenic glucoside content in leaves and tubers: distribution of cyanogenic glucosides, their site of synthesis and transport, and blockage of the biosynthesis by RNA interference technology. Plant Physiol 139: 363-374
    • (2005) Plant Physiol , vol.139 , pp. 363-374
    • Jørgensen, K.1    Bak, S.2    Busk, P.K.3    Sørensen, C.4    Olsen, C.E.5    Puonti-Kaerlas, J.6    Møller, B.L.7
  • 28
    • 0031397803 scopus 로고    scopus 로고
    • Isolation and reconstitution of cytochrome P450ox and in vitro reconstitution of the entire biosynthetic pathway of the cyanogenic glucoside dhurrin from sorghum
    • Kahn RA, Bak S, Svendsen I, Halkier BA, Møller BL (1997) Isolation and reconstitution of cytochrome P450ox and in vitro reconstitution of the entire biosynthetic pathway of the cyanogenic glucoside dhurrin from sorghum. Plant Physiol 115: 1661-1670
    • (1997) Plant Physiol , vol.115 , pp. 1661-1670
    • Kahn, R.A.1    Bak, S.2    Svendsen, I.3    Halkier, B.A.4    Møller, B.L.5
  • 29
    • 0026530834 scopus 로고
    • The biosynthesis of cyanogenic glucosides in seedlings of cassava (Manihot esculenta Crantz)
    • Koch B, Nielsen VS, Halkier BA, Olsen CE, Møller BL (1992) The biosynthesis of cyanogenic glucosides in seedlings of cassava (Manihot esculenta Crantz). Arch Biochem Biophys 292: 141-150
    • (1992) Arch Biochem Biophys , vol.292 , pp. 141-150
    • Koch, B.1    Nielsen, V.S.2    Halkier, B.A.3    Olsen, C.E.4    Møller, B.L.5
  • 30
    • 0028834385 scopus 로고
    • The primary sequence of cytochrome P450tyr, the multifunctional N-hydroxylase catalyzing the conversion of L-tyrosine to p-hydroxyphenylacetaldehyde oxime in the biosynthesis of the cyanogenic glucoside dhurrin in Sorghum bicolor (L.) Moench
    • Koch BM, Sibbesen O, Halkier BA, Svendsen I, Møller BL (1995) The primary sequence of cytochrome P450tyr, the multifunctional N-hydroxylase catalyzing the conversion of L-tyrosine to p-hydroxyphenylacetaldehyde oxime in the biosynthesis of the cyanogenic glucoside dhurrin in Sorghum bicolor (L.) Moench. Arch Biochem Biophys 323: 177-186
    • (1995) Arch Biochem Biophys , vol.323 , pp. 177-186
    • Koch, B.M.1    Sibbesen, O.2    Halkier, B.A.3    Svendsen, I.4    Møller, B.L.5
  • 31
    • 13444249488 scopus 로고    scopus 로고
    • Metabolic engineering of dhurrin in transgenic Arabidopsis plants with marginal inadvertent effects on the metabolome and transcriptome
    • Kristensen C, Morant M, Olsen CE, Ekstrøm CT, Galbraith DW, Møller BL, Bak S (2005) Metabolic engineering of dhurrin in transgenic Arabidopsis plants with marginal inadvertent effects on the metabolome and transcriptome. Proc Natl Acad Sci USA 102: 1779-1784
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 1779-1784
    • Kristensen, C.1    Morant, M.2    Olsen, C.E.3    Ekstrøm, C.T.4    Galbraith, D.W.5    Møller, B.L.6    Bak, S.7
  • 32
    • 78650982295 scopus 로고    scopus 로고
    • Conformational changes of the NADPH-dependent cytochrome P450 reductase in the course of electron transfer to cytochromes P450
    • (in press)
    • Laursen T, Jensen K, Møller BL (2010) Conformational changes of the NADPH-dependent cytochrome P450 reductase in the course of electron transfer to cytochromes P450. Biochim Biophys Acta (in press)
    • (2010) Biochim Biophys Acta
    • Laursen, T.1    Jensen, K.2    Møller, B.L.3
  • 33
    • 0011216893 scopus 로고
    • Cyanogenic glycosides in cassava, Manihot esculenta Crantz
    • Lykkesfeldt J, Møller BL (1994) Cyanogenic glycosides in cassava, Manihot esculenta Crantz. Acta Chem Scand A 48: 178-180
    • (1994) Acta Chem Scand A , vol.48 , pp. 178-180
    • Lykkesfeldt, J.1    Møller, B.L.2
  • 34
    • 70450199290 scopus 로고    scopus 로고
    • Changes in total carotenoid content at different stages of traditional processing of yellowfleshed cassava genotypes
    • Maziya-Dixon B, Dixon AGO, Ssemakula G (2009) Changes in total carotenoid content at different stages of traditional processing of yellowfleshed cassava genotypes. Int J Food Sci Technol 44: 2350-2357
    • (2009) Int J Food Sci Technol , vol.44 , pp. 2350-2357
    • Maziya-Dixon, B.1    Dixon, A.G.O.2    Ssemakula, G.3
  • 35
    • 78650981453 scopus 로고    scopus 로고
    • Functioning dependent metabolons
    • (in press)
    • Møller BL (2010) Functioning dependent metabolons. Science (in press)
    • (2010) Science
    • Møller, B.L.1
  • 36
    • 0002958809 scopus 로고
    • The biosynthesis of cyanogenic glucosides in higher plants: N-hydroxytyrosine as an intermediate in the biosynthesis of dhurrin by Sorghum bicolor (Linn) Moench
    • Møller BL, Conn EE (1979) The biosynthesis of cyanogenic glucosides in higher plants: N-hydroxytyrosine as an intermediate in the biosynthesis of dhurrin by Sorghum bicolor (Linn) Moench. J Biol Chem 254: 8575-8583
    • (1979) J Biol Chem , vol.254 , pp. 8575-8583
    • Møller, B.L.1    Conn, E.E.2
  • 37
    • 0040106748 scopus 로고
    • The biosynthesis of cyanogenic glucosides in higher plants: Channeling of intermediates in dhurrin biosynthesis by a microsomal system from Sorghum bicolor (Linn) Moench
    • Møller BL, Conn EE (1980) The biosynthesis of cyanogenic glucosides in higher plants: channeling of intermediates in dhurrin biosynthesis by a microsomal system from Sorghum bicolor (Linn) Moench. J Biol Chem 255: 3049-3056
    • (1980) J Biol Chem , vol.255 , pp. 3049-3056
    • Møller, B.L.1    Conn, E.E.2
  • 41
    • 0141787883 scopus 로고    scopus 로고
    • CYP83A1 and CYP83B1, two nonredundant cytochrome P450 enzymes metabolizing oximes in the biosynthesis of glucosinolates in Arabidopsis
    • Naur P, Petersen BL, Mikkelsen MD, Bak S, Rasmussen H, Olsen CE, Halkier BA (2003) CYP83A1 and CYP83B1, two nonredundant cytochrome P450 enzymes metabolizing oximes in the biosynthesis of glucosinolates in Arabidopsis. Plant Physiol 133: 63-72
    • (2003) Plant Physiol , vol.133 , pp. 63-72
    • Naur, P.1    Petersen, B.L.2    Mikkelsen, M.D.3    Bak, S.4    Rasmussen, H.5    Olsen, C.E.6    Halkier, B.A.7
  • 42
    • 0002590197 scopus 로고
    • Evolutionary argument for a connection between drug metabolism and signal transduction
    • In, Libbey Eurotext, Paris
    • Nebert DW, Feyereisen R (1994) Evolutionary argument for a connection between drug metabolism and signal transduction. In Cytochrome P450 8th International Conference. Libbey Eurotext, Paris, pp 3-13
    • (1994) Cytochrome P450 8th International Conference , pp. 3-13
    • Nebert, D.W.1    Feyereisen, R.2
  • 43
    • 3042674420 scopus 로고    scopus 로고
    • Comparative genomics of rice and Arabidopsis: Analysis of 727 cytochrome P450 genes and pseudogenes from a monocot and a dicot
    • Nelson DR, Schuler MA, Paquette SM, Werck-Reichhart D, Bak S (2004) Comparative genomics of rice and Arabidopsis: analysis of 727 cytochrome P450 genes and pseudogenes from a monocot and a dicot. Plant Physiol 135: 756-772
    • (2004) Plant Physiol , vol.135 , pp. 756-772
    • Nelson, D.R.1    Schuler, M.A.2    Paquette, S.M.3    Werck-Reichhart, D.4    Bak, S.5
  • 44
    • 33746010247 scopus 로고    scopus 로고
    • Acute cyanide toxicity: Mechanisms and manifestations
    • Nelson L (2006) Acute cyanide toxicity: mechanisms and manifestations. J Emerg Nurs (Suppl) 32: S8-S11
    • (2006) J Emerg Nurs , vol.32 , Issue.SUPPL.
    • Nelson, L.1
  • 49
    • 50449100139 scopus 로고
    • Carbon monoxide-binding pigment of liver microsomes. II. Solubilization, purification and properties
    • Omura T, Sato R (1964) Carbon monoxide-binding pigment of liver microsomes. II. Solubilization, purification and properties. J Biol Chem 239: 2379-2385
    • (1964) J Biol Chem , vol.239 , pp. 2379-2385
    • Omura, T.1    Sato, R.2
  • 50
    • 0033866508 scopus 로고    scopus 로고
    • Intron-exon organization and phylogeny in a large superfamily, the paralogous cytochrome P450 genes of Arabidopsis thaliana
    • Paquette SM, Bak S, Feyereisen R (2000) Intron-exon organization and phylogeny in a large superfamily, the paralogous cytochrome P450 genes of Arabidopsis thaliana. DNA Cell Biol 19: 307-317
    • (2000) DNA Cell Biol , vol.19 , pp. 307-317
    • Paquette, S.M.1    Bak, S.2    Feyereisen, R.3
  • 51
    • 70549098814 scopus 로고    scopus 로고
    • A Web-based resource for the Arabidopsis P450, cytochromes b5, NADPH-cytochrome P450 reductases, and family 1 glycosyltransferases
    • Paquette SM, Jensen K, Bak S (2009) A Web-based resource for the Arabidopsis P450, cytochromes b5, NADPH-cytochrome P450 reductases, and family 1 glycosyltransferases (http://www.P450.kvl.dk). Phytochemistry 70: 1940-1947
    • (2009) Phytochemistry , vol.70 , pp. 1940-1947
    • Paquette, S.M.1    Jensen, K.2    Bak, S.3
  • 52
    • 0029776005 scopus 로고    scopus 로고
    • Yeast expression of animal and plant P450s in optimized redox environments
    • Pompon D, Louerat B, Bronine A, Urban P (1996) Yeast expression of animal and plant P450s in optimized redox environments. Cytochrome P450 272: 51-64
    • (1996) Cytochrome P450 , vol.272 , pp. 51-64
    • Pompon, D.1    Louerat, B.2    Bronine, A.3    Urban, P.4
  • 53
    • 70350722406 scopus 로고    scopus 로고
    • Evolution of camalexin and structurally related indolic compounds
    • Rauhut T, Glawischnig E (2009) Evolution of camalexin and structurally related indolic compounds. Phytochemistry 70: 1638-1644
    • (2009) Phytochemistry , vol.70 , pp. 1638-1644
    • Rauhut, T.1    Glawischnig, E.2
  • 54
    • 0001743005 scopus 로고
    • Measuring effects in humans of dietary cyanide exposure from cassava
    • Rosling H (1994) Measuring effects in humans of dietary cyanide exposure from cassava. Acta Hortic 375: 271-283
    • (1994) Acta Hortic , vol.375 , pp. 271-283
    • Rosling, H.1
  • 55
    • 0028985451 scopus 로고
    • Cytochrome P-450TYR is a multifunctional heme-thiolate enzyme catalyzing the conversion of L-tyrosine to p-hydroxyphenylacetaldehyde oxime in the biosynthesis of the cyanogenic glucoside dhurrin in Sorghum bicolor (L.) Moench
    • Sibbesen O, Koch B, Halkier BA, Møller BL (1995) Cytochrome P-450TYR is a multifunctional heme-thiolate enzyme catalyzing the conversion of L-tyrosine to p-hydroxyphenylacetaldehyde oxime in the biosynthesis of the cyanogenic glucoside dhurrin in Sorghum bicolor (L.) Moench. J Biol Chem 270: 3506-3511
    • (1995) J Biol Chem , vol.270 , pp. 3506-3511
    • Sibbesen, O.1    Koch, B.2    Halkier, B.A.3    Møller, B.L.4
  • 57
    • 3242655621 scopus 로고    scopus 로고
    • Metabolic channeling in plants
    • Winkel BSJ (2004) Metabolic channeling in plants. Annu Rev Plant Biol 55: 85-107
    • (2004) Annu Rev Plant Biol , vol.55 , pp. 85-107
    • Winkel, B.S.J.1
  • 58
    • 1642465417 scopus 로고    scopus 로고
    • Two cassava promoters related to vascular expression and storage root formation
    • Zhang P, Bohl-Zenger S, Puonti-Kaerlas J, Potrykus I, Gruissem W (2003) Two cassava promoters related to vascular expression and storage root formation. Planta 218: 192-203
    • (2003) Planta , vol.218 , pp. 192-203
    • Zhang, P.1    Bohl-Zenger, S.2    Puonti-Kaerlas, J.3    Potrykus, I.4    Gruissem, W.5
  • 59
    • 0036206383 scopus 로고    scopus 로고
    • Method optimization for the determination of carbonyl compounds in disinfected water by DNPH derivatization and LC-ESI-MS-MS
    • Zwiener C, Glauner T, Frimmel FH (2002) Method optimization for the determination of carbonyl compounds in disinfected water by DNPH derivatization and LC-ESI-MS-MS. Anal Bioanal Chem 372: 615-621
    • (2002) Anal Bioanal Chem , vol.372 , pp. 615-621
    • Zwiener, C.1    Glauner, T.2    Frimmel, F.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.