The arabidopsis ref2 mutant is defective in the gene encoding CYP83A1 and shows both phenylpropanoid and glucosinolate phenotypes

Plant Cell

Volumn 15, Issue 1, 2003, Pages 179-194

  Hemm, Matthew R ^a   Ruegger, Max O ^a,b   Chapple, Clint ^a  

^a PURDUE UNIVERSITY   (United States)

^b DOW AGROSCIENCES LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CLONING; ENZYMES; FLUORESCENCE; GENES; LIGNIN; METABOLISM; MUTAGENESIS; SEED; ULTRAVIOLET RADIATION;

GLUCOSINOLATE; PHENYLPROPANOID;

PLANTS (BOTANY);

ARABIDOPSIS; BRASSICALES; EMBRYOPHYTA; SPERMATOPHYTA;

EID: 0037256698     PISSN: 10404651     EISSN: None     Source Type: Journal    
DOI: 10.1105/tpc.006544     Document Type: Article

References (60)

1. Bak, S., and Feyereisen, R. (2001). The involvement of two P450 enzymes, CYP83B1 and CYP83A1, in auxin homeostasis and glucosinolate biosynthesis. Plant Physiol. 127, 108-118.
2. Bak, S., Tax, F.E., Feldmann, K.A., Galbraith, D.W., and Feyereisen, R. (2001). CYP83B1, a cytochrome P450 at the metabolic branch paint in auxin and indole glucosinolate biosynthesis in Arabidopsis. Plant Cell 13, 101-111.
3. Barlier, I., Kowalczyk, M., Marchant, A., Ljung, K., Bhalerao, R., Bennett, M., Sandberg, G., and Bellini, C. (2000). The SUR2 gene of Arabidopsis thaliana encodes the cytochrome P450 CYP83B1, a modulator of auxin homeostasis. Proc. Natl. Acad. Sci. USA 97, 14819-14824.
4. Bell, C.J., and Ecker, J.R. (1994). Assignment of 30 microsatellite loci to the linkage map of Arabidopsis. Genomics 19, 137-144.
5. Bennett, R.N., Hick, A.J., Dawson, G.W., and Wallsgrove, R.M. (1995). Glucosinolate biosynthesis: Further characterization of the aldoxime-forming microsomal monooxygenases in oilseed rape leaves. Plant Physiol. 109, 299-305.
6. Bilodeau, P., Udvardi, M.K., Peacock, W.J., and Dennis, E.S. (1999). A prolonged cold treatment-induced cytochrome P450 gene from Arabidopsis thaliana. Plant Cell Environ. 22, 791-800.
7. Booij-James, I.S., Dube, S.K., Jansen, M.A.K., Edelman, M., and Mattoo, A.K. (2000). Ultraviolet-B radiation impacts light-mediated turnover of the photosystem II reaction center heterodimer in Arabidopsis mutants altered in phenolic metabolism. Plant Physiol. 124, 1275-1283.
8. Chapple, C. (1998). Molecular-genetic analysis of plant cytochrome P450-dependent monooxygenases. Annu. Rev. Plant Physiol. Plant Mol. Biol. 49, 311-343.
9. Chapple, C.C.S. (1995). A cDNA encoding a novel cytochrome P450-dependent monooxygenase from Arabidopsis thaliana. Plant Physiol. 108, 875-876.
10. Chapple, C.C.S., Shirley, B.W., Zook, M., Hammerschmidt, R., and Somerville, S.C. (1994). Secondary metabolism in Arabidopsis. In Arabidopsis, E.M. Meyerowitz and C.R. Somerville, eds (Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press), pp. 989-1030.
11. Chapple, C.C.S., Vogt, T., Ellis, B.E., and Somerville, C.R. (1992). An Arabidopsis mutant defective in the general phenylpropanoid pathway. Plant Cell 4, 1413-1424.
12. Chen, S., and Andreassan, E. (2001). Update on glucosinolate metabolism and transport. Plant Physiol. Biochem. 39, 743-759.
13. Chow, I.T., and Gasser, C.S. (1997). Characterization of the cyclophilin gene family of Arabidopsis thaliana and phylogenetic analysis of known cyclophilin proteins. Plant Mol. Biol. 35, 873-892.
14. Clough, S.J., and Bent, A.F. (1998). Floral dip: A simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana. Plant J. 16, 735-743.
15. Dawson, G.W., Hick, A.J., Bennett, R.N., Donald, A., Pickett, J.A., and Wallsgrove, R.M. (1993). Synthesis of glucosinolate precursors and investigations into the biosynthesis of phenylalkyl- and methylthioalkylglucosinolates. J. Biol. Chem. 268, 27154-27159.
16. Delarue, M., Prinsen, E., Onckelen, H.V., Caboche, M., and Bellini, C. (1998). sur2 mutations of Arabidopsis thaliana define a new locus involved in the control of auxin homeostasis. Plant J. 14, 603-611.
17. Edwards, R., and Dixon, R.A. (1991). Purification and characterization of S-adenosyl-L-methionine:caffeic acid 3-O-methyltransferase from suspension cultures of alfalfa (Medicago sativa L.). Arch. Biochem. Biophys. 287, 372-379.
18. Fabri, C.O., and Schaffner, A.R. (1994). An Arabidopsis thaliana RFLP mapping set to localize mutations to chromosomal regions. Plant J. 5, 149-156.
19. Franke, R., Hemm, M.R., Denault, J.W., Ruegger, M.O., Humphreys, J.M., and Chapple, C. (2002a). Changes in secondary metabolism and deposition of an unusual lignin in the ref8 mutant of Arabidopsis. Plant J. 30, 47-59.
20. Franke, R., Humphreys, J.M., Hemm, M.R., Denault, J.W., Ruegger, M.O., Cusumano, J.C., and Chapple, C. (2002b). The Arabidopsis REF8 gene encodes the 3-hydroxylase of phenylpropanoid metabolism. Plant J. 30, 33-45.
21. Franke, R., McMichael, C.M., Meyer, K., Shirley, A.M., Cusumano, J.C., and Chapple, C. (2000). Modified lignin in tobacco and poplar plants over-expressing the Arabidopsis gene encoding ferulate 5-hydroxylase. Plant J. 22, 223-234.
22. Glover, J.R., Chapple, C.C.S., Rothwell, S., Tober, I., and Ellis, B.E. (1988). Allylglucosinolate biosynthesis in Brassica carinata. Phytochemistry 27, 1345-1348.
23. Goldsbrough, P.B., and Cullis, C.A. (1981). Characterization of the genes for ribosomal RNA in flax. Nucleic Acids Res. 9, 1301-1309.
24. Graham, S.E., and Peterson, J.A. (1999). How similar are P450s and what can their differences teach us? Arch. Biochem. Biophys. 369, 24-29.
25. Graser, G., Oldham, N.J., Brown, P.D., Temp, U., and Gershenzon, J. (2001). The biosynthesis of benzoic acid glucosinolate esters in Arabidopsis thaliana. Phytochemistry 57, 23-32.
26. Halkier, B.A., and Du, L. (1997). The biosynthesis of glucosinolates. Trends Plant Sci. 2, 425-431.
27. Hansen, C.H., Du, L.C., Naur, P., Olsen, C.E., Axelsen, K.B., Hick, A.J., Pickett, J.A., and Halkier, B.A. (2001). CYP83B1 is the oxime-metabolizing enzyme in the glucosinolate pathway in Arabidopsis. J. Biol. Chem. 276, 24790-24796.
28. Hilleren, P., and Parker, R. (1999). mRNA surveillance in eukaryotes: Kinetic proofreading of proper translation termination as assessed by mRNP domain organization? RNA 5, 711-719.
29. Hull, A.K., Vij, R., and Celenza, J.L. (2000). Arabidopsis cytochrome P450s that catalyze the first step of tryptophan-dependent indole-3-acetic acid biosynthesis. Proc. Natl. Acad. Sci. USA 97, 2379-2384.
30. Humphreys, J.M., and Chapple, C. (2002). Rewriting the lignin roadmap. Curr. Opin. Plant Biol. 5, 224-229.
31. Humphreys, J.M., Hemm, M.R., and Chapple, C. (1999). New routes for lignin biosynthesis defined by biochemical characterization of recombinant ferulate 5-hydroxylase, a multifunctional cytochrome P450-dependent monooxygenase. Proc. Natl. Acad. Sci. USA 96, 10045-10050.
32. Inoue, K., Sewalt, V.J.H., Balance, G.M., Ni, W., Stürzer, C., and Dixon, R. (1998). Developmental expression and substrate specificities of alfalfa caffeic acid 3-O-methyltransferase and caffeoyl coenzyme A 3-O-methyltransferase in relation to lignification. Plant Physiol. 117, 761-770.
33. Jones, M.L., and Woodson, W.R. (1999). Differential expression of three members of the 1-aminocyclopropane-1-carboxylate synthase gene family in carnation. Plant Physiol. 119, 755-764.
34. Kaar, W.E., and Brink, D.L. (1991). Simplified analysis of acid-soluble lignin. J. Wood Chem. Technol. 11, 465-477.
35. Kiddle, G., Bennett, R.N., Botting, N.P., Davidson, N.E., Robertson, A.A.B., and Wallsgrove, R.M. (2001). High-performance liquid chromatographic separation of natural and synthetic desulphoglucosinolates and their chemical validation by UV, NMR, and chemical ionisation-MS methods. Phytochem. Anal. 12, 226-242.
36. Kliebenstein, D.J., Gershenzon, J., and Mitchell-Olds, T. (2001). Comparative quantitative trait loci mapping of aliphatic, indolic and benzylic glucosinolate production in Arabidopsis thaliana leaves and seeds. Genetics 159, 359-370.
37. Konieczny, A., and Ausubel, F.M. (1993). A procedure for mapping Arabidopsis mutations using co-dominant ecotype-specific PCR-based markers. Plant J. 4, 403-410.
38. Lambrix, V., Reichelt, M., Mitchell-Olds, T., Kliebenstein, D.J., and Gershenzon, J. (2001). The Arabidopsis epithiospecifier protein promotes the hydrolysis of glucosinolates to nitriles and influences Trichoplusia ni herbivory. Plant Cell 13, 2793-2807.
39. Landry, L.G., Chapple, C.C.S., and Last, R.L. (1995). Arabidopsis mutants lacking phenolic sunscreens exhibit enhanced ultraviolet-B injury and oxidative damage. Plant Physiol. 109, 1159-1166.
40. Lehfeldt, C., Shirley, A.M., Meyer, K., Ruegger, M.O., Cusumano, J.C., Viitanen, P.V., Strack, D., and Chapple, C. (2000). Cloning of the SNG1 gene of Arabidopsis reveals a role for serine carboxy-peptidase-like protein as an acyltransferase in secondary metabolism. Plant Cell 12, 1295-1306.
41. Lewis, N.G., and Yamamoto, E. (1990). Lignin: Occurrence, biogenesis and biodegradation. Annu. Rev. Plant Physiol. Plant Mol. Biol. 41, 455-496.
42. Lu, F.C., and Ralph, J. (1997). Derivatization followed by reductive cleavage (DFRC method), a new method for lignin analysis: Protocol for analysis of DFRC monomers. J. Agric. Food Chem. 45, 2590-2592.
43. Meyer, K., Benning, G., and Grill, E. (1996). Cloning of plant genes based on genetic map location. In Genome Mapping in Plants, A.H. Paterson, ed (New York: Academic Press/Austin, TX: Landes Bioscience Publishers), pp. 137-154.
44. Meyer, K., Shirley, A.M., Cusumano, J.C., Bell-Lelong, D.A., and Chapple, C. (1998). Lignin monomer composition is determined by the expression of a cytochrome P450-dependent monooxygenase in Arabidopsis. Proc. Natl. Acad. Sci. USA 95, 6619-6623.
45. Mikkelsen, M.D., Hansen, C.H., Wittstock, U., and Halkier, B.A. (2000). Cytochrome P450CYP79B2 from Arabidopsis catalyzes the conversion of tryptophan to indole-3-acetaldoxime, a precursor of indole glucosinolates and indole-3-acetic acid. J. Biol. Chem. 275, 33712-33717.
46. Murashige, T., and Skoog, F. (1962). A revised medium for rapid growth and bioassays with tobacco tissue culture. Physiol. Plant. 15, 473-497.
47. Osakabe, K., Tsao, C.C., Li, L.G., Popko, J.L., Umezawa, T., Carraway, D.T., Smetzer, R.H., Joshi, C.P., and Chiang, V.L. (1999). Coniferyl aldehyde 5-hydroxylation and methylation direct syringyl lignin biosynthesis in angiosperms. Proc. Natl. Acad. Sci. USA 96, 8955-8960.
48. Petersen, B.L., Chen, S.X., Hansen, C.H., Olsen, C.E., and Halkier, B.A. (2002). Composition and content of glucosinolates in developing Arabidopsis thaliana. Planta 214, 562-571.
49. Reintanz, B., Lehnen, M., Reichelt, M., Gershenzon, J., Kowalczyk, M., Sandberg, G., Godde, M., Uhl, R., and Palme, K. (2001). bus, a bushy Arabidopsis CYP79F1 knockout mutant with abolished synthesis of short-chain aliphatic glucosinolates. Plant Cell 13, 351-367.
50. Ruegger, M., and Chapple, C. (2001). Mutations that reduce sinapoylmalate accumulation in Arabidopsis thaliana define loci with diverse roles in phenylpropanoid metabolism. Genetics 159, 1741-1749.
51. Ruegger, M., Meyer, K., Cusumano, J.C., and Chapple, C. (1999). Regulation of ferulate-5-hydroxylase expression in Arabidopsis in the context of sinapate ester biosynthesis. Plant Physiol. 119, 101-110.
52. Schaffner, A. (1996). pARMS, multiple marker-containing plasmids for easy RFLP analysis in Arabidopsis thaliana. Plant Mol. Biol. Rep. 14, 11-16.
53. Shirley, A.M., McMichael, C.M., and Chapple, C. (2001). The sng2 mutant of Arabidopsis is defective in the gene encoding the serine carboxypeptidase-like protein sinapoylglucose:choline sinapoyl-transferase. Plant J. 28, 83-94.
54. Siminszky, B., Corbin, F.T., Ward, E.R., Fleischmann, T.J., and Dewey, R.E. (1999). Expression of a soybean cytochrome P450 monooxygenase cDNA in yeast and tobacco enhances the metabolism of phenylurea herbicides. Proc. Natl. Acad. Sci. USA 96, 1750-1755.
55. Simpson, G.S., McQuade, C., Lyon, J., and Brown, J.W.S. (1998). Characterization of exon skipping mutants of the COP1 gene from Arabidopsis. Plant J. 15, 125-131.
56. Strack, D. (1977). Sinapic acid ester fluctuations in cotyledons of Raphanus sativus. Z. Pflanzenphysiol. 84, 139-145.
57. Strack, D. (1981). Sinapine as a supply of choline for the biosynthesis of phosphatidylcholine in Raphanus sativus seedlings. Z. Naturforsch. 36c, 215-221.
58. Tahara, S., and Ibrahim, R.K. (1995). Prenylated isoflavonoids: An update. Phytochemistry 38, 1073-1094.
59. Tantikanjana, T., Yong, J.W.H., Letham, D.S., Griffith, M., Ljung, K., Sandberg, G., and Sundaresan, V. (2001). Control of axillary bud initiation and shoot architecture in Arabidopsis through the SUPERSHOOT gene. Genes Dev. 15, 1577-1588.
60. Zambrisky, P., Joos, H., Genetello, C., Leemans, J., van Montagu, M., and Schell, J. (1983). Ti plasmid vector for the introduction of DNA into plant cells without alteration of their normal regeneration capacity. EMBO J. 2, 2143-2150.