High-throughput screening of improved protease inhibitors using a yeast cell surface display system and a yeast cell chip

Journal of Bioscience and Bioengineering

Volumn 111, Issue 1, 2011, Pages 16-18

  Aoki, Wataru ^a,b   Yoshino, Yuichi ^b   Morisaka, Hironobu ^b   Tsunetomo, Keiji ^c   Koyo, Hirotaka ^c   Kamiya, Shinji ^c   Kawata, Noriyuki ^c   Kuroda, Kouichi ^b   Ueda, Mitsuyoshi ^b  

^a JAPAN SOCIETY FOR THE PROMOTION OF SCIENCE   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c NIPPON SHEET GLASS CO LTD   (Japan)

Author keywords

Automatic single cell pickup machine; High throughput screening system; Matrix metalloprotease; Neurolysin; Protease inhibitor; Yeast cell chip; Yeast cell surface display

Indexed keywords

AUTOMATIC SINGLE-CELL PICKUP MACHINE; HIGH-THROUGHPUT SCREENING SYSTEMS; MATRIX METALLOPROTEASE; NEUROLYSIN; PROTEASE INHIBITOR; YEAST CELL CHIP; YEAST CELL SURFACE DISPLAY;

CELL MEMBRANES; DISPLAY DEVICES; ENZYME INHIBITION; THROUGHPUT; YEAST;

CYTOLOGY;

HYBRID PROTEIN; MATRIX METALLOPROTEINASE 2/9 INHIBITOR III; MATRIX METALLOPROTEINASE INHIBITOR; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CELL SURFACE; CONTROLLED STUDY; DISPLAY SYSTEM; ENZYME INHIBITION; HIGH THROUGHPUT SCREENING; NONHUMAN; YEAST CELL; YEAST CELL SURFACE DISPLAY;

DRUG EVALUATION, PRECLINICAL; HIGH-THROUGHPUT SCREENING ASSAYS; IMMUNOGLOBULIN LIGHT CHAINS; METALLOENDOPEPTIDASES; PROTEASE INHIBITORS; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE;

EID: 78650992445     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiosc.2010.08.006     Document Type: Article

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