A proteomic analysis of C-reactive protein stimulated THP-1 monocytes

Proteome Science

Volumn 9, Issue , 2011, Pages

  Eisenhardt, Steffen U ^a,b   Habersberger, Jonathon ^a   Oliva, Karen ^a   Lancaster, Graeme I ^a   Ayhan, Mustafa ^a   Woollard, Kevin J ^a   Bannasch, Holger ^b   Rice, Greg E ^a,c   Peter, Karlheinz ^a  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTININ 4; ALPHA ENOLASE; C REACTIVE PROTEIN; HEAT SHOCK PROTEIN 70; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; POLYSTYRENE; UBIQUITIN PROTEIN LIGASE;

ARTICLE; CELL LYSATE; HUMAN; HUMAN CELL; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MONOCYTE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN EXPRESSION; PROTEOMICS; UPREGULATION; WESTERN BLOTTING;

EID: 78650974075     PISSN: None     EISSN: 14775956     Source Type: Journal    
DOI: 10.1186/1477-5956-9-1     Document Type: Article

References (44)

1. Eisenhardt SU, Habersberger J, Murphy A, Chen YC, Woollard KJ, Bassler N, Qian H, von Zur Muhlen C, Hagemeyer CE, Ahrens I, et al. Dissociation of pentameric to monomeric C-reactive protein on activated platelets localizes inflammation to atherosclerotic plaques. Circ Res 2009, 105:128-137. 10.1161/CIRCRESAHA.108.190611, 19520972.
2. Khreiss T, Jozsef L, Potempa LA, Filep JG. Conformational rearrangement in C-reactive protein is required for proinflammatory actions on human endothelial cells. Circulation 2004, 109:2016-2022. 10.1161/01.CIR.0000125527.41598.68, 15051635.
3. Khreiss T, Jozsef L, Potempa LA, Filep JG. Loss of pentameric symmetry in C-reactive protein induces interleukin-8 secretion through peroxynitrite signaling in human neutrophils. Circ Res 2005, 97:690-697. 10.1161/01.RES.0000183881.11739.CB, 16123332.
4. Molins B, Pena E, Vilahur G, Mendieta C, Slevin M, Badimon L. C-reactive protein isoforms differ in their effects on thrombus growth. Arterioscler Thromb Vasc Biol 2008, 28:2239-2246. 10.1161/ATVBAHA.108.174359, 18787187.
5. Khreiss T, Jozsef L, Potempa LA, Filep JG. Opposing effects of C-reactive protein isoforms on shear-induced neutrophil-platelet adhesion and neutrophil aggregation in whole blood. Circulation 2004, 110:2713-2720. 10.1161/01.CIR.0000146846.00816.DD, 15492312.
6. Verma S, Devaraj S, Jialal I. Is C-reactive protein an innocent bystander or proatherogenic culprit? C-reactive protein promotes atherothrombosis. Circulation 2006, 113:2135-2150. discussion 2150.
7. Libby P, Ridker PM, Maseri A. Inflammation and atherosclerosis. Circulation 2002, 105:1135-1143. 10.1161/hc0902.104353, 11877368.
8. Guha M, Mackman N. LPS induction of gene expression in human monocytes. Cell Signal 2001, 13:85-94. 10.1016/S0898-6568(00)00149-2, 11257452.
9. Xie L, Chang L, Guan Y, Wang X. C-reactive protein augments interleukin-8 secretion in human peripheral blood monocytes. J Cardiovasc Pharmacol 2005, 46:690-696. 10.1097/01.fjc.0000183568.48389.a1, 16220077.
10. Woollard KJ, Phillips DC, Griffiths HR. Direct modulatory effect of C-reactive protein on primary human monocyte adhesion to human endothelial cells. Clin Exp Immunol 2002, 130:256-262. 10.1046/j.1365-2249.2002.01978.x, 1906519, 12390313.
11. Devaraj S, Davis B, Simon SI, Jialal I. CRP promotes monocyte-endothelial cell adhesion via Fcgamma receptors in human aortic endothelial cells under static and shear flow conditions. Am J Physiol Heart Circ Physiol 2006, 291:H1170-1176. 10.1152/ajpheart.00150.2006, 16603696.
12. Hanriot D, Bello G, Ropars A, Seguin-Devaux C, Poitevin G, Grosjean S, Latger-Cannard V, Devaux Y, Zannad F, Regnault V, et al. C-reactive protein induces pro- and anti-inflammatory effects, including activation of the liver X receptor alpha, on human monocytes. Thromb Haemost 2008, 99:558-569.
13. Schwedler SB, Amann K, Wernicke K, Krebs A, Nauck M, Wanner C, Potempa LA, Galle J. Native C-reactive protein increases whereas modified C-reactive protein reduces atherosclerosis in apolipoprotein E-knockout mice. Circulation 2005, 112:1016-1023. 10.1161/CIRCULATIONAHA.105.556530, 16087790.
14. Zouki C, Haas B, Chan JS, Potempa LA, Filep JG. Loss of pentameric symmetry of C-reactive protein is associated with promotion of neutrophil-endothelial cell adhesion. J Immunol 2001, 167:5355-5361.
15. Khreiss T, Jozsef L, Hossain S, Chan JS, Potempa LA, Filep JG. Loss of pentameric symmetry of C-reactive protein is associated with delayed apoptosis of human neutrophils. J Biol Chem 2002, 277:40775-40781. 10.1074/jbc.M205378200, 12198121.
16. Singh U, Devaraj S, Dasu MR, Ciobanu D, Reusch J, Jialal I. C-reactive protein decreases interleukin-10 secretion in activated human monocyte-derived macrophages via inhibition of cyclic AMP production. Arterioscler Thromb Vasc Biol 2006, 26:2469-2475. 10.1161/01.ATV.0000241572.05292.fb, 16917108.
17. Eisenhardt SU, Habersberger J, Peter K. Monomeric C-reactive protein generation on activated platelets: the missing link between inflammation and atherothrombotic risk. Trends Cardiovasc Med 2009, 19:232-237. 10.1016/j.tcm.2010.02.002, 20382347.
18. Eisenhardt SU, Thiele JR, Bannasch H, Stark GB, Peter K. C-reactive protein: how conformational changes influence inflammatory properties. Cell Cycle 2009, 8:3885-3892.
19. Habersberger J, Eisenhardt S, Peter K. C-reactive protein measurement and cardiovascular disease. Lancet 2010, 375:1078. 10.1016/S0140-6736(10)60470-9, 20346805.
20. Herrmann J, Soares SM, Lerman LO, Lerman A. Potential role of the ubiquitin-proteasome system in atherosclerosis: aspects of a protein quality disease. J Am Coll Cardiol 2008, 51:2003-2010. 10.1016/j.jacc.2008.02.047, 18498952.
21. Bukau B, Weissman J, Horwich A. Molecular chaperones and protein quality control. Cell 2006, 125:443-451. 10.1016/j.cell.2006.04.014, 16678092.
22. Herrmann J, Edwards WD, Holmes DR, Shogren KL, Lerman LO, Ciechanover A, Lerman A. Increased ubiquitin immunoreactivity in unstable atherosclerotic plaques associated with acute coronary syndromes. J Am Coll Cardiol 2002, 40:1919-1927. 10.1016/S0735-1097(02)02564-0, 12475450.
23. Versari D, Herrmann J, Gossl M, Mannheim D, Sattler K, Meyer FB, Lerman LO, Lerman A. Dysregulation of the ubiquitin-proteasome system in human carotid atherosclerosis. Arterioscler Thromb Vasc Biol 2006, 26:2132-2139. 10.1161/01.ATV.0000232501.08576.73, 16778122.
24. Marfella R, D'Amico M, Di Filippo C, Baldi A, Siniscalchi M, Sasso FC, Portoghese M, Carbonara O, Crescenzi B, Sangiuolo P, et al. Increased activity of the ubiquitin-proteasome system in patients with symptomatic carotid disease is associated with enhanced inflammation and may destabilize the atherosclerotic plaque: effects of rosiglitazone treatment. J Am Coll Cardiol 2006, 47:2444-2455. 10.1016/j.jacc.2006.01.073, 16781372.
25. Nouspikel T, Hanawalt PC. Impaired nucleotide excision repair upon macrophage differentiation is corrected by E1 ubiquitin-activating enzyme. Proc Natl Acad Sci USA 2006, 103:16188-16193. 10.1073/pnas.0607769103, 1621053, 17060614.
26. Ryan KA, Smith MF, Sanders MK, Ernst PB. Reactive oxygen and nitrogen species differentially regulate Toll-like receptor 4-mediated activation of NF-kappa B and interleukin-8 expression. Infect Immun 2004, 72:2123-2130. 10.1128/IAI.72.4.2123-2130.2004, 375203, 15039334.
27. Berberian PA, Myers W, Tytell M, Challa V, Bond MG. Immunohistochemical localization of heat shock protein-70 in normal-appearing and atherosclerotic specimens of human arteries. Am J Pathol 1990, 136:71-80. 1877454, 2297051.
28. Radford NB, Fina M, Benjamin IJ, Moreadith RW, Graves KH, Zhao P, Gavva S, Wiethoff A, Sherry AD, Malloy CR, Williams RS. Cardioprotective effects of 70-kDa heat shock protein in transgenic mice. Proc Natl Acad Sci USA 1996, 93:2339-2342. 10.1073/pnas.93.6.2339, 39797, 8637874.
29. Mestril R, Chi SH, Sayen MR, O'Reilly K, Dillmann WH. Expression of inducible stress protein 70 in rat heart myogenic cells confers protection against simulated ischemia-induced injury. J Clin Invest 1994, 93:759-767. 10.1172/JCI117030, 293923, 8113409.
30. Barderas MG, Tunon J, Darde VM, De la Cuesta F, Duran MC, Jimenez-Nacher JJ, Tarin N, Lopez-Bescos L, Egido J, Vivanco F. Circulating human monocytes in the acute coronary syndrome express a characteristic proteomic profile. J Proteome Res 2007, 6:876-886. 10.1021/pr0601990, 17269745.
31. Yasuda K, Ishihara K, Nakashima K, Hatayama T. Genomic cloning and promoter analysis of the mouse 105-kDa heat shock protein (HSP105) gene. Biochem Biophys Res Commun 1999, 256:75-80. 10.1006/bbrc.1999.0283, 10066425.
32. Hatayama T, Yasuda K. Association of HSP105 with HSC70 in high molecular mass complexes in mouse FM3A cells. Biochem Biophys Res Commun 1998, 248:395-401. 10.1006/bbrc.1998.8979, 9675148.
33. Yamagishi N, Ishihara K, Saito Y, Hatayama T. Hsp105 but not Hsp70 family proteins suppress the aggregation of heat-denatured protein in the presence of ADP. FEBS Lett 2003, 555:390-396. 10.1016/S0014-5793(03)01292-4, 14644449.
34. Das R, Burke T, Plow EF. Histone H2B as a functionally important plasminogen receptor on macrophages. Blood 2007, 110:3763-3772. 10.1182/blood-2007-03-079392, 2077321, 17690254.
35. Bottalico LA, Kendrick NC, Keller A, Li Y, Tabas I. Cholesteryl ester loading of mouse peritoneal macrophages is associated with changes in the expression or modification of specific cellular proteins, including increase in an alpha-enolase isoform. Arterioscler Thromb 1993, 13:264-275.
36. Celli L, Ryckewaert JJ, Delachanal E, Duperray A. Evidence of a functional role for interaction between ICAM-1 and nonmuscle alpha-actinins in leukocyte diapedesis. J Immunol 2006, 177:4113-4121.
37. Li N, Mak A, Richards DP, Naber C, Keller BO, Li L, Shaw AR. Monocyte lipid rafts contain proteins implicated in vesicular trafficking and phagosome formation. Proteomics 2003, 3:536-548. 10.1002/pmic.200390067, 12687620.
38. Jovic M, Naslavsky N, Rapaport D, Horowitz M, Caplan S. EHD1 regulates beta1 integrin endosomal transport: effects on focal adhesions, cell spreading and migration. J Cell Sci 2007, 120:802-814. 10.1242/jcs.03383, 17284518.
39. Hynes RO. Integrins: bidirectional, allosteric signaling machines. Cell 2002, 110:673-687. 10.1016/S0092-8674(02)00971-6, 12297042.
40. Pepys MB, Hawkins PN, Kahan MC, Tennent GA, Gallimore JR, Graham D, Sabin CA, Zychlinsky A, de Diego J. Proinflammatory effects of bacterial recombinant human C-reactive protein are caused by contamination with bacterial products, not by C-reactive protein itself. Circ Res 2005, 97:e97-103. 10.1161/01.RES.0000193595.03608.08, 1400607, 16254214.
41. Marnell L, Mold C, Du Clos TW. C-reactive protein: ligands, receptors and role in inflammation. Clin Immunol 2005, 117:104-111. 10.1016/j.clim.2005.08.004, 16214080.
42. Ji SR, Ma L, Bai CJ, Shi JM, Li HY, Potempa LA, Filep JG, Zhao J, Wu Y. Monomeric C-reactive protein activates endothelial cells via interaction with lipid raft microdomains. Faseb J 2009, 23:1806-1816. 10.1096/fj.08-116962, 19136614.
43. Kang JH, Kim HT, Choi MS, Lee WH, Huh TL, Park YB, Moon BJ, Kwon OS. Proteome analysis of human monocytic THP-1 cells primed with oxidized low-density lipoproteins. Proteomics 2006, 6:1261-1273. 10.1002/pmic.200500290, 16402358.
44. Potempa LA, Siegel JN, Fiedel BA, Potempa RT, Gewurz H. Expression, detection and assay of a neoantigen (Neo-CRP) associated with a free, human C-reactive protein subunit. Mol Immunol 1987, 24:531-541. 10.1016/0161-5890(87)90028-9, 2443837.