-
2
-
-
57349160286
-
Medical management of hyperglycaemia in type 2 diabetes mellitus: A consensus algorithm for the initiation and adjustment of therapy: A consensus statement from the American Diabetes Association and the European Association for the Study of Diabetes
-
American Diabetes Association; European Association for the Study of Diabetes
-
Nathan DM, Buse JB, Davidson MB, Ferrannini E, Holman RR, Sherwin R, Zinman B, American Diabetes Association; European Association for the Study of Diabetes. Medical management of hyperglycaemia in type 2 diabetes mellitus: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement from the American Diabetes Association and the European Association for the Study of Diabetes. Diabetologia 2009 52 17-30
-
(2009)
Diabetologia
, vol.52
, pp. 17-30
-
-
Nathan, D.M.1
Buse, J.B.2
Davidson, M.B.3
Ferrannini, E.4
Holman, R.R.5
Sherwin, R.6
Zinman, B.7
-
3
-
-
33749479230
-
AMP-activated protein kinase: Role in metabolism and therapeutic implications
-
Schimmack G, Defronzo RA, Musi N. AMP-activated protein kinase: Role in metabolism and therapeutic implications. Diabetes Obes Metab 2006 8 591-602
-
(2006)
Diabetes Obes Metab
, vol.8
, pp. 591-602
-
-
Schimmack, G.1
Defronzo, R.A.2
Musi, N.3
-
4
-
-
74949121815
-
AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK- and PDK1-dependent activation of atypical PKC
-
Sajan MP, Bandyopadhyay G, Miura A, Standaert ML, Nimal S, Longnus SL, Van Obberghen E, Hainault I, Foufelle F, Kahn R, Braun U, Leitges M, Farese RV. AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK- and PDK1-dependent activation of atypical PKC. Am J Physiol Endocrinol Metab 2010 298 E179-E192
-
(2010)
Am J Physiol Endocrinol Metab
, vol.298
-
-
Sajan, M.P.1
Bandyopadhyay, G.2
Miura, A.3
Standaert, M.L.4
Nimal, S.5
Longnus, S.L.6
Van Obberghen, E.7
Hainault, I.8
Foufelle, F.9
Kahn, R.10
Braun, U.11
Leitges, M.12
Farese, R.V.13
-
5
-
-
77954933558
-
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
-
Foretz M, Hebrard S, Leclerc J, Zarrinpashneh E, Soty M, Mithieux G, Sakamoto K, Andreelli F, Viollet B. Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state. J Clin Invest 2010 120 2355-2369
-
(2010)
J Clin Invest
, vol.120
, pp. 2355-2369
-
-
Foretz, M.1
Hebrard, S.2
Leclerc, J.3
Zarrinpashneh, E.4
Soty, M.5
Mithieux, G.6
Sakamoto, K.7
Andreelli, F.8
Viollet, B.9
-
6
-
-
70649104753
-
Glucose, metformin, and AICAR regulate the expression of G protein-coupled receptor members in INS-1 beta cell
-
Pan QR, Li WH, Wang H, Sun Q, Xiao XH, Brock B, Schmitz O. Glucose, metformin, and AICAR regulate the expression of G protein-coupled receptor members in INS-1 beta cell. Horm Metab Res 2009 41 799-804
-
(2009)
Horm Metab Res
, vol.41
, pp. 799-804
-
-
Pan, Q.R.1
Li, W.H.2
Wang, H.3
Sun, Q.4
Xiao, X.H.5
Brock, B.6
Schmitz, O.7
-
7
-
-
77955044321
-
Metformin attenuates production of nitric oxide in response to lipopolysaccharide by inhibiting MyD88-independent pathway
-
Kato Y, Koide N, Komatsu T, Tumurkhuu G, Dagvadorj J, Kato K, Yokochi T. Metformin attenuates production of nitric oxide in response to lipopolysaccharide by inhibiting MyD88-independent pathway. Horm Metab Res 2010 42 632-636
-
(2010)
Horm Metab Res
, vol.42
, pp. 632-636
-
-
Kato, Y.1
Koide, N.2
Komatsu, T.3
Tumurkhuu, G.4
Dagvadorj, J.5
Kato, K.6
Yokochi, T.7
-
8
-
-
3843115467
-
Imidazoline binding sites and their ligands: An overview of the different chemical structures
-
Dardonville C, Rozas I. Imidazoline binding sites and their ligands: an overview of the different chemical structures. Med Res Rev 2004 24 639-661
-
(2004)
Med Res Rev
, vol.24
, pp. 639-661
-
-
Dardonville, C.1
Rozas, I.2
-
9
-
-
0028990748
-
I1-imidazoline receptors. Definition, characterization, distribution, and transmembrane signaling
-
Ernsberger P, Graves ME, Graff LM, Zakieh N, Nguyen P, Collins LA, Westbrooks KL, Johnson GG. I1-imidazoline receptors. Definition, characterization, distribution, and transmembrane signaling. Ann NY Acad Sci 1995 763 22-42
-
(1995)
Ann NY Acad Sci
, vol.763
, pp. 22-42
-
-
Ernsberger, P.1
Graves, M.E.2
Graff, L.M.3
Zakieh, N.4
Nguyen, P.5
Collins, L.A.6
Westbrooks, K.L.7
Johnson, G.G.8
-
10
-
-
0032799426
-
Imidazolines and pancreatic hormone secretion
-
Morgan NG, Chan SL, Mourtada M, Monks LK, Ramsden CA. Imidazolines and pancreatic hormone secretion. Ann NY Acad Sci 1999 881 217-228
-
(1999)
Ann NY Acad Sci
, vol.881
, pp. 217-228
-
-
Morgan, N.G.1
Chan, S.L.2
Mourtada, M.3
Monks, L.K.4
Ramsden, C.A.5
-
11
-
-
77951499084
-
Activation of imidazoline I2B receptors is linked with AMP kinase pathway to increase glucose uptake in cultured C2C12 cells
-
Lui TN, Tsao CW, Huang SY, Chang CH, Cheng JT. Activation of imidazoline I2B receptors is linked with AMP kinase pathway to increase glucose uptake in cultured C2C12 cells. Neurosci Lett 2010 474 144-147
-
(2010)
Neurosci Lett
, vol.474
, pp. 144-147
-
-
Lui, T.N.1
Tsao, C.W.2
Huang, S.Y.3
Chang, C.H.4
Cheng, J.T.5
-
12
-
-
72549092423
-
Increase of beta-endorphin secretion by agmatine is induced by activation of imidazoline I(2A) receptors in adrenal gland of rats
-
Chang CH, Wu HT, Cheng KC, Lin HJ, Cheng JT. Increase of beta-endorphin secretion by agmatine is induced by activation of imidazoline I(2A) receptors in adrenal gland of rats. Neurosci Lett 2010 468 297-299
-
(2010)
Neurosci Lett
, vol.468
, pp. 297-299
-
-
Chang, C.H.1
Wu, H.T.2
Cheng, K.C.3
Lin, H.J.4
Cheng, J.T.5
-
13
-
-
0026074359
-
Subcellular distribution of imidazoline-guanidinium-receptive sites in human and rabbit liver. Major localization to the mitochondrial outer membrane
-
Tesson F, Prip-Buus C, Lemoine A, Pegorier JP, Parini A. Subcellular distribution of imidazoline-guanidinium-receptive sites in human and rabbit liver. Major localization to the mitochondrial outer membrane. J Biol Chem 1991 266 155-160
-
(1991)
J Biol Chem
, vol.266
, pp. 155-160
-
-
Tesson, F.1
Prip-Buus, C.2
Lemoine, A.3
Pegorier, J.P.4
Parini, A.5
-
14
-
-
0036810873
-
Plasma glucose-lowering effect of beta-endorphin in streptozotocin- induced diabetic rats
-
Cheng JT, Liu IM, Tzeng TF, Tsai CC, Lai TY. Plasma glucose-lowering effect of beta-endorphin in streptozotocin-induced diabetic rats. Horm Metab Res 2002 34 570-576
-
(2002)
Horm Metab Res
, vol.34
, pp. 570-576
-
-
Cheng, J.T.1
Liu, I.M.2
Tzeng, T.F.3
Tsai, C.C.4
Lai, T.Y.5
-
15
-
-
33644767124
-
Novel mechanism for plasma glucose-lowering action of metformin in streptozotocin-induced diabetic rats
-
Cheng JT, Huang CC, Liu IM, Tzeng TF, Chang CJ. Novel mechanism for plasma glucose-lowering action of metformin in streptozotocin-induced diabetic rats. Diabetes 2006 55 819-825
-
(2006)
Diabetes
, vol.55
, pp. 819-825
-
-
Cheng, J.T.1
Huang, C.C.2
Liu, I.M.3
Tzeng, T.F.4
Chang, C.J.5
-
16
-
-
17844362774
-
Activation of imidazoline receptors in adrenal gland to lower plasma glucose in streptozotocin-induced diabetic rats
-
Hwang SL, Liu IM, Tzeng TF, Cheng JT. Activation of imidazoline receptors in adrenal gland to lower plasma glucose in streptozotocin-induced diabetic rats. Diabetologia 2005 48 767-775
-
(2005)
Diabetologia
, vol.48
, pp. 767-775
-
-
Hwang, S.L.1
Liu, I.M.2
Tzeng, T.F.3
Cheng, J.T.4
-
17
-
-
70350780057
-
Activation of imidazoline I(2B) receptors by guanidine to increase glucose uptake in skeletal muscle of rats
-
Chang CH, Tsao CW, Huang SY, Cheng JT. Activation of imidazoline I(2B) receptors by guanidine to increase glucose uptake in skeletal muscle of rats. Neurosci Lett 2009 467 147-149
-
(2009)
Neurosci Lett
, vol.467
, pp. 147-149
-
-
Chang, C.H.1
Tsao, C.W.2
Huang, S.Y.3
Cheng, J.T.4
-
18
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
Zhou G, Myers R, Li Y, Chen Y, Shen X, Fenyk-Melody J, Wu M, Ventre J, Doebber T, Fujii N, Musi N, Hirshman MF, Goodyear LJ, Moller DE. Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest 2001 108 1167-1174
-
(2001)
J Clin Invest
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
Myers, R.2
Li, Y.3
Chen, Y.4
Shen, X.5
Fenyk-Melody, J.6
Wu, M.7
Ventre, J.8
Doebber, T.9
Fujii, N.10
Musi, N.11
Hirshman, M.F.12
Goodyear, L.J.13
Moller, D.E.14
-
19
-
-
27944459864
-
Mediation of Endogenous beta-endorphin by Tetrandrine to Lower Plasma Glucose in Streptozotocin-induced Diabetic Rats
-
Hsu JH, Wu YC, Liou SS, Liu IM, Huang LW, Cheng JT. Mediation of Endogenous beta-endorphin by Tetrandrine to Lower Plasma Glucose in Streptozotocin-induced Diabetic Rats. Evid Based Complement Alternat Med 2004 1 193-201
-
(2004)
Evid Based Complement Alternat Med
, vol.1
, pp. 193-201
-
-
Hsu, J.H.1
Wu, Y.C.2
Liou, S.S.3
Liu, I.M.4
Huang, L.W.5
Cheng, J.T.6
-
20
-
-
32544432088
-
Mediation of beta-endorphin by myricetin to lower plasma glucose in streptozotocin-induced diabetic rats
-
Liu IM, Liou SS, Cheng JT. Mediation of beta-endorphin by myricetin to lower plasma glucose in streptozotocin-induced diabetic rats. J Ethnopharmacol 2006 104 199-206
-
(2006)
J Ethnopharmacol
, vol.104
, pp. 199-206
-
-
Liu, I.M.1
Liou, S.S.2
Cheng, J.T.3
-
21
-
-
0030971211
-
Effect of beta-endorphin C-terminal peptides on glucose uptake in isolated skeletal muscles of the mouse
-
Evans A, Smith ME. Effect of beta-endorphin C-terminal peptides on glucose uptake in isolated skeletal muscles of the mouse. Peptides 1997 18 165-167
-
(1997)
Peptides
, vol.18
, pp. 165-167
-
-
Evans, A.1
Smith, M.E.2
-
22
-
-
33645721222
-
Metformin increases insulin sensitivity and plasma beta-endorphin in human subjects
-
Ou HY, Cheng JT, Yu EH, Wu TJ. Metformin increases insulin sensitivity and plasma beta-endorphin in human subjects. Horm Metab Res 2006 38 106-111
-
(2006)
Horm Metab Res
, vol.38
, pp. 106-111
-
-
Ou, H.Y.1
Cheng, J.T.2
Yu, E.H.3
Wu, T.J.4
-
23
-
-
0037169233
-
Increase of beta-endorphin biosynthesis in the adrenal gland of streptozotocin-induced diabetic rats
-
Hsu CT, Liu IM, Cheng JT. Increase of beta-endorphin biosynthesis in the adrenal gland of streptozotocin-induced diabetic rats. Neurosci Lett 2002 318 57-60
-
(2002)
Neurosci Lett
, vol.318
, pp. 57-60
-
-
Hsu, C.T.1
Liu, I.M.2
Cheng, J.T.3
-
24
-
-
50249104779
-
Adrenocortical dysfunction in obesity and the metabolic syndrome
-
Krug AW, Ehrhart-Bornstein M. Adrenocortical dysfunction in obesity and the metabolic syndrome. Horm Metab Res 2008 40 515-517
-
(2008)
Horm Metab Res
, vol.40
, pp. 515-517
-
-
Krug, A.W.1
Ehrhart-Bornstein, M.2
-
25
-
-
0025973233
-
Imidazoline-guanidinium and alpha 2-adrenergic binding sites in basolateral membranes from human kidney
-
Lachaud-Pettiti V, Podevin RA, Chretien Y, Parini A. Imidazoline- guanidinium and alpha 2-adrenergic binding sites in basolateral membranes from human kidney. Eur J Pharmacol 1991 206 23-31
-
(1991)
Eur J Pharmacol
, vol.206
, pp. 23-31
-
-
Lachaud-Pettiti, V.1
Podevin, R.A.2
Chretien, Y.3
Parini, A.4
-
26
-
-
0025156752
-
Imidazoline-guanidinium receptive site in renal proximal tubule: Asymmetric distribution, regulation by cations and interaction with an endogenous clonidine displacing substance
-
Coupry I, Atlas D, Podevin RA, Uzielli I, Parini A. Imidazoline- guanidinium receptive site in renal proximal tubule: asymmetric distribution, regulation by cations and interaction with an endogenous clonidine displacing substance. J Pharmacol Exp Ther 1990 252 293-299
-
(1990)
J Pharmacol Exp Ther
, vol.252
, pp. 293-299
-
-
Coupry, I.1
Atlas, D.2
Podevin, R.A.3
Uzielli, I.4
Parini, A.5
-
27
-
-
34547206822
-
Receptor-mediated activation of nitric oxide synthesis by arginine in endothelial cells
-
Joshi MS, Ferguson TB Jr, Johnson FK, Johnson RA, Parthasarathy S, Lancaster JR Jr. Receptor-mediated activation of nitric oxide synthesis by arginine in endothelial cells. Proc Natl Acad Sci USA 2007 104 9982-9987
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 9982-9987
-
-
Joshi, M.S.1
Ferguson, Jr.T.B.2
Johnson, F.K.3
Johnson, R.A.4
Parthasarathy, S.5
Lancaster, Jr.J.R.6
-
28
-
-
0032796367
-
Pharmacologic and molecular discrimination of I2-imidazoline receptor subtypes
-
Olmos G, Alemany R, Boronat MA, Garcia-Sevilla JA. Pharmacologic and molecular discrimination of I2-imidazoline receptor subtypes. Ann NY Acad Sci 1999 881 144-160
-
(1999)
Ann NY Acad Sci
, vol.881
, pp. 144-160
-
-
Olmos, G.1
Alemany, R.2
Boronat, M.A.3
Garcia-Sevilla, J.A.4
-
29
-
-
0027441984
-
Discrimination and pharmacological characterization of I2-imidazoline sites with [3H]idazoxan and alpha-2 adrenoceptors with [3H]RX821002 (2-methoxy idazoxan) in the human and rat brains
-
Miralles A, Olmos G, Sastre M, Barturen F, Martin I, Garcia-Sevilla JA. Discrimination and pharmacological characterization of I2-imidazoline sites with [3H]idazoxan and alpha-2 adrenoceptors with [3H]RX821002 (2-methoxy idazoxan) in the human and rat brains. J Pharmacol Exp Ther 1993 264 1187-1197
-
(1993)
J Pharmacol Exp Ther
, vol.264
, pp. 1187-1197
-
-
Miralles, A.1
Olmos, G.2
Sastre, M.3
Barturen, F.4
Martin, I.5
Garcia-Sevilla, J.A.6
-
30
-
-
0026579106
-
Imidazoline binding sites in human placenta: Evidence for heterogeneity and a search for physiological function
-
Diamant S, Eldar-Geva T, Atlas D. Imidazoline binding sites in human placenta: evidence for heterogeneity and a search for physiological function. Br J Pharmacol 1992 106 101-108
-
(1992)
Br J Pharmacol
, vol.106
, pp. 101-108
-
-
Diamant, S.1
Eldar-Geva, T.2
Atlas, D.3
|